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Eugene Braunwald and the Rise of Modern Medicine by Thomas H. Lee Pdf
Much of the improved survival rate from heart attack can be traced to Eugene Braunwald's work. He proved that myocardial infarction was an hours-long dynamic process which could be altered by treatment. Thomas H. Lee tells the life story of a physician whose activist approach transformed not just cardiology but the culture of American medicine.
Eugene Braunwald and the Rise of Modern Medicine by Thomas H. Lee Pdf
Much of the improved survival rate from heart attack can be traced to Eugene Braunwald's work. He proved that myocardial infarction was an hours-long dynamic process which could be altered by treatment. Thomas H. Lee tells the life story of a physician whose activist approach transformed not just cardiology but the culture of American medicine.
Eugene Braunwald and the Rise of Modern Medicine by Thomas H. Lee Pdf
Since the 1950s, the death rate from heart attacks has plunged from 35 percent to about 5 percent--and fatalistic attitudes toward this disease and many others have faded into history. Much of the improved survival and change in attitudes can be traced to the work of Eugene Braunwald, MD. In the 1960s, he proved that myocardial infarction was not a "bolt from the blue" but a dynamic process that plays out over hours and thus could be altered by treatment. By redirecting cardiology from passive, risk-averse observation to active intervention, he helped transform not just his own field but the culture of American medicine. Braunwald's personal story demonstrates how the forces of history affected the generation of researchers responsible for so many medical advances in the second half of the twentieth century. In 1938 Nazi occupiers forced his family to flee Vienna for Brooklyn. Because of Jewish quotas in medical schools, he was the last person admitted to his class, but went on to graduate number one. When the Doctor Draft threatened to interrupt his medical training during the Korean War, he joined the National Institutes of Health instead of the Navy, and there he began the research that made him the most influential cardiologist of his time. In Eugene Braunwald and the Rise of Modern Medicine, Thomas H. Lee offers insights that only authoritative firsthand interviews can provide, to bring us closer to this iconic figure in modern medicine.
Seven million people die from cancer each year around the world, and many more are impacted by this universal scourge. In Betrayed by Nature, research scientist and lecturer Robin Hesketh demystifies the nature of cancer. Hesketh provides a concise and comprehensive history of both the science and the medical advances made over the decades. He takes the reader on a riveting tour of human biology; he explains how cancers start, what is meant by ‘a mutation', and how mutations can make cells grow abnormally and spread around our bodies. Drawing on the latest discoveries from the Human Genome Project, Hesketh reveals the strides being made in understanding this malevolent disease and makes accessible the science of today's treatments. Betrayed by Nature looks forward to the day when many cancers can be treated readily and effectively. With cancer afflicting one in three people worldwide, this is an illuminating and optimistic look at the past, present, and future of cancer.
At the turn of the twentieth century, smallpox claimed the lives of two million people per year. By 1979, the disease had been eradicated and victory was declared across the globe. Yet the story of smallpox remains the exception, as today a host of deadly contagions, from polio to AIDS, continue to threaten human health around the world. Spanning three centuries, The End of Plagues weaves together the discovery of vaccination, the birth and growth of immunology, and the fight to eradicate the world's most feared diseases. From Edward Jenner's discovery of vaccination in 1796, to the early nineteenth-century foundling voyages in which chains of orphans, vaccinated one by one, were sent to colonies around the globe, to the development of polio vaccines and the stockpiling of smallpox as a biological weapon in the Cold War, world-renown immunologist John Rhodes charts our fight against these plagues, and shows how vaccinations gave humanity the upper hand. Today, aid groups including the Bill and Melinda Gates Foundation and the World Health Organization have made the eradication of polio a priority, and Rhodes takes us behind the scenes to witness how soon we may be celebrating the eradication of polio.
Author : Thomas H. Lee,James J. Mongan Publisher : MIT Press Page : 295 pages File Size : 47,9 Mb Release : 2012-02-10 Category : Medical ISBN : 9780262258364
Chaos and Organization in Health Care by Thomas H. Lee,James J. Mongan Pdf
Two leading physicians' prescription for solving our health care problems: organizing the fragmented system that delivers care. One of the most daunting challenges facing the new U.S. administration is health care reform. The size of the system, the number of stakeholders, and ever-rising costs make the problem seem almost intractable. But in Chaos and Organization in Health Care, two leading physicians offer an optimistic prognosis. In their frontline work as providers, Thomas Lee and James Mongan see the inefficiency, the missed opportunities, and the occasional harm that can result from the current system. The root cause of these problems, they argue, is chaos in the delivery of care. If the problem is chaos, the solution is organization, and in this timely and outspoken book, they offer a plan. In many ways, this chaos is caused by something good: the dramatic progress in medical science—the explosion of medical knowledge and the exponential increase in treatment options. Imposed on a fragmented system of small practices and individual patients with multiple providers, progress results in chaos. Lee and Mongan argue that attacking this chaos is even more important than whether health care is managed by government or controlled by market forces. Some providers are already tightly organized, adapting management principles from business and offering care that is by many measures safer, better, and less costly. Lee and Mongan propose multiple strategies that can be adopted nationwide, including electronic medical records and information systems for sharing knowledge; team-based care, with doctors and other providers working together; and disease management programs to coordinate care for the sickest patients.
Author : Michael Bliss Publisher : University of Toronto Press Page : 626 pages File Size : 41,5 Mb Release : 2002-04-01 Category : History ISBN : 0802085415
In his time the most famous physician in the world, Canadian-born William Osler (1849-1919) is still the best-known figure in the history of medicine. This new, definitive biography by Michael Bliss is the first full-scale life of Osler to appear since 1925. An award-winning medical historian, Bliss draws on many untapped sources to recreate Osler's life and medical times for a new generation of readers. Born at Bond Head, north of Toronto, Osler rose from obscurity to become the greatest medical teacher and writer in three countries. At Canada's McGill University, America's Johns Hopkins University, and finally as regius professor at Oxford, Osler was idolized by two generations of medical students and practitioners, for whom he came to personify the ideal doctor. His quest was to bring high standards and scientific methods into general practice in the medical world and to give teaching hospitals a solid place in the education of doctors. The publication of his book, The Principles and Practice of Medicine (1892), established him as the authority of modern medicine, a position he held well into the new century. Osler was revered as the high priest of the advent of twentieth-century medicine. In this fine biography, Michael Bliss animates the epic quality of Osler's life - not only in telling his personal story, but in setting that story against the dramatic backdrop of the coming of modern medicine. Winner of the Jason A. Hannah Medal, awarded by the Royal Society of Canada and the Hannah Institute for the History of Medicine
In 1862 the Salpêtrière Hospital in Paris became the epicenter of the study of hysteria, the mysterious illness then thought to affect half of all women. There, prominent neurologist Jean-Martin Charcot's contentious methods caused furore within the church and divided the medical community. Treatments included hypnosis, piercing and the evocation of demons and, despite the controversy they caused, the experiments became a fascinating and fashionable public spectacle. Medical Muses tells the stories of the women institutionalised in the Salpêtrière. Theirs is a tale of science and ideology, medicine and the occult, of hypnotism, sadism, love and theatre. Combining hospital records, municipal archives, memoirs and letters, Medical Muses sheds new light on a crucial moment in psychiatric history.
Did you know... Medical interventions have become the third leading cause of death in America. An estimated 10 percent of Americans are implanted with medical devices -- like pacemakers, artificial hips, cardiac stents, etc. The overwhelming majority of high-risk implanted devices have never undergone a single clinical trial. In The Danger Within Us, award-winning journalist Jeanne Lenzer brings these horrifying statistics to life through the story of one working class man who, after his "cure" nearly kills him, ends up in a battle for justice against the medical establishment. His crusade leads Lenzer on a journey through the dark underbelly of the medical device industry, a fascinating and disturbing world that hasn't been written about before. What Lenzer exposes will shock readers: rampant corruption, elaborate cover-ups, shameless profiteering, and astonishing lack of oversight, all of which leads to dangerous devices (from artificial hips to pacemakers) going to market and into our bodies. In the vein of America's Bitter Pill and A Civil Action, The Danger Within Us is a stirring call for reform and a must-read for anyone who cares about the future of American healthcare. "Before you get anything implanted in your body, read this book."-Shannon Brownlee, author of Overtreated
This study explores the parallel histories of the Mayo Clinic, the care of patients with heart disease, and specialization in cardiology during the twentieth century. Chapters are devoted to such technologies as open-heart surgery, coronary angiography, and echocardiography, and to the key individuals, instituions, and innovations that played vital roles in the technologies that transformed heart care.--From publisher description.
Medicine: Preserving the Passion by Phil R. Manning,Lois DeBakey Pdf
In Medicine: Preserving the Passion, Phil R. Manning, a pioneer and recognized authority in continuing medical education, and Lois DeBakey, a passionate advocate of critical reasoning and leading scholar in scientific communication, endeavor to shift the focus in lifelong learning from group exercises in a lecture hall to self-directed, practice-related activities. Al though most experts have applauded this new concept, few publications have addressed methods for implementation. The Manning-DeBakey book describes such methods as devised by outstanding clinicians and acade micians to obtain educational benefit from their clinical experience. Some techniques inspired by quality assurance, for example, these master cli nicians have used successfully to improve their knowledge, skills, and patient care. This book not only identifies the primary concerns in con tinuing medical education, but also offers sound recommendations and effective solutions and suggests future directions and approaches. The authors have analyzed the continuing educational practices of phy sicians in a wide range of environments, from small communities to the most acclaimed medical centers, and have extracted additional advice from the writings of past authorities like Osler. The resulting concepts will un doubtedly attract wide public attention. Office practice audit, self-directed learning, case indexing, patient education, computer-assisted education, and collegial networks, as well as regular reading, writing, and teaching, are among the successful methods described by physicians and surgeons who exemplify the highest standards of medical practice.
Principles and Practice of Clinical Trials by Steven Piantadosi,Curtis L. Meinert Pdf
This is a comprehensive major reference work for our SpringerReference program covering clinical trials. Although the core of the Work will focus on the design, analysis, and interpretation of scientific data from clinical trials, a broad spectrum of clinical trial application areas will be covered in detail. This is an important time to develop such a Work, as drug safety and efficacy emphasizes the Clinical Trials process. Because of an immense and growing international disease burden, pharmaceutical and biotechnology companies continue to develop new drugs. Clinical trials have also become extremely globalized in the past 15 years, with over 225,000 international trials ongoing at this point in time. Principles in Practice of Clinical Trials is truly an interdisciplinary that will be divided into the following areas: 1) Clinical Trials Basic Perspectives 2) Regulation and Oversight 3) Basic Trial Designs 4) Advanced Trial Designs 5) Analysis 6) Trial Publication 7) Topics Related Specific Populations and Legal Aspects of Clinical Trials The Work is designed to be comprised of 175 chapters and approximately 2500 pages. The Work will be oriented like many of our SpringerReference Handbooks, presenting detailed and comprehensive expository chapters on broad subjects. The Editors are major figures in the field of clinical trials, and both have written textbooks on the topic. There will also be a slate of 7-8 renowned associate editors that will edit individual sections of the Reference.
In State of the Heart, Dr. Haider Warraich takes readers inside the ER, inside patients' rooms, and inside the history and science of cardiac disease. State of the Heart traces the entire arc of the heart, from the very first time it was depicted on stone tablets, to a future in which it may very well become redundant. While heart disease has been around for a while, the type of heart disease people have, why they have it, and how it’s treated is changing. Yet, the golden age of heart science is only just beginning. And with treatments of heart disease altering the very definitions of human life and death, there is no better time to look at the present and future of heart disease, the doctors and nurses who treat it, the patients and caregivers who live with it, and the stories they hold close to their chests. More people die of heart disease than any other disease in the world and when any form of heart disease progresses, it can result in the development of heart failure. Heart failure affects millions and can affect anyone at anytime, a child recovering from a viral infection, a woman who has just given birth or a cancer patient receiving chemotherapy. Yet new technology to treat heart failure is fundamentally changing just what it means to be human. Mechanical pumps can be surgically sown into patients’ hearts and when patients with these pumps get really sick, sometimes they don’t need a doctor or a surgeon—they need a mechanic. In State of the Heart, the journey to rid the world of heart disease is shown to be reflective of the journey of medical science at large. We are learning not only that women have as much heart disease as men, but that the type of heart disease women experience is diametrically different from that in men. We are learning that heart disease and cancer may have more in common than we could have imagined. And we are learning how human evolution itself may have led to the epidemic of heart disease. In understanding how our knowledge of the heart evolved, State of the Heart traces the twisting and turning road that science has taken—filled with potholes and blind turns—all the way back to its very origin.
Author : Thomas H Lee Publisher : McGraw Hill Professional Page : 240 pages File Size : 52,9 Mb Release : 2019-11-15 Category : Business & Economics ISBN : 9781260459210
The Good Doctor: What It Means, How to Become One, and How to Remain One by Thomas H Lee Pdf
What does it mean to be a good doctor today? Dr. Thomas Lee, a renowned practicing physician, healthcare executive, researcher, and policy expert, takes us to the frontlines of care delivery to meet inspiring, transformative doctors who are making a profound difference in patients’ lives—as well as their own. These revealing, intimate profiles of seven remarkable physicians are more than a reminder of the importance of putting patients first. They provide an invaluable working model of what it means to be a good doctor, how to become one, and how to remain one for the benefit of patients and colleagues alike. It’s a model that sustains physicians themselves over years and decades, combating the constant threat of burnout. These stories capture the daily challenges every caregiver faces—while highlighting the amazing personal triumphs that make their jobs so rewarding. You’ll meet Dr. Emily Sedgwick, the breast radiologist who redesigned screening techniques to reduce patients’ fears; Dr. Merit Cudkowicz, a neurologist who is leading the way in ALS research and treatments; Dr. Mike Englesbe, a transplant surgeon who is improving how physicians prescribe analgesics in response to the opioid epidemic; Dr. Laura Monson, a pediatric plastic surgeon addressing the long-term social effects of cleft palates; Dr. Lara Johnson, a primary care physician dedicated to providing care to the homeless; Dr. Joseph Sakran, a trauma surgeon who started a movement among healthcare providers to curb gun violence, and Dr. Babacar Cisse, a neurosurgeon who was an undocumented alien and once worked as a restaurant busboy, and epitomizes what it means to be a “Dreamer.” Their stories are not only powerful but offer practical lessons and insights into developing high reliability cultures, resilience, and improvement mindsets. This is what is takes to be a good doctor.