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Evolutionary Systems Biology by Orkun S. Soyer Pdf
The book aims to introduce the reader to the emerging field of Evolutionary Systems Biology, which approaches classical systems biology questions within an evolutionary framework. An evolutionary approach might allow understanding the significance of observed diversity, uncover “evolutionary design principles” and extend predictions made in model organisms to others. In addition, evolutionary systems biology can generate new insights into the adaptive landscape by combining molecular systems biology models and evolutionary simulations. This insight can enable the development of more detailed mechanistic evolutionary hypotheses.
Evolutionary Systems Biology by Anton Crombach Pdf
This new edition captures the advances made in the field of evolutionary systems biology since the publication of the first edition. The first edition focused on laying the foundations of evolutionary systems biology as an interdisciplinary field, where a way of thinking and asking questions is combined with a wide variety of tools, both experimental and theoretical/computational. Since publication of the first edition, evolutionary systems biology is now a well-known term describing this growing field. The new edition provides an overview of the current status and future developments of this interdisciplinary field. Chapters highlight several key achievements from the last decade and outline exciting new developments, including an understanding of the interplay between complexity and predictability in evolutionary systems, new viewpoints and methods to study organisms in evolving populations at the level of the genome, gene regulatory network, and metabolic network, and better analysis and modeling techniques that will open new avenues of scientific inquiry.
Systems Evolutionary Biology: Biological Network Evolution Theory, Stochastic Evolutionary Game Strategies, and Applications to Systems Synthetic Biology discusses the evolutionary game theory and strategies of nonlinear stochastic biological networks under random genetic variations and environmental disturbances and their application to systematic synthetic biology design. The book provides more realistic stochastic biological system models to mimic the real biological systems in evolutionary process and then introduces network evolvability, stochastic evolutionary game theory and strategy based on nonlinear stochastic networks in evolution. Readers will find remarkable, revolutionary information on genetic evolutionary biology that be applied to economics, engineering and bioscience. Explains network fitness, network evolvability and network robustness of biological networks from the systematic perspective Discusses the evolutionary noncooperative and cooperative game strategies of biological networks Offers detailed diagrams to help readers understand biological networks, their systematic behaviors and the simulational results of evolutionary biological networks Includes examples in every chapter with computational simulation to illustrate the solution procedure of evolutionary theory, strategy and results
Evolutionary Genomics and Systems Biology by Gustavo Caetano-Anollés Pdf
A comprehensive, authoritative look at an emergent area in post-genomic science, Evolutionary genomics is an up-and-coming, complex field that attempts to explain the biocomplexity of the living world. Evolutionary Genomics and Systems Biology is the first full-length book to blend established and emerging concepts in bioinformatics, evolution, genomics, and structural biology, with the integrative views of network and systems biology. Three key aspects of evolutionary genomics and systems biology are covered in clear detail: the study of genomic history, i.e., understanding organismal evolution at the genomic level; the study of macromolecular complements, which encompasses the evolution of the protein and RNA machinery that propels life; and the evolutionary and dynamic study of wiring diagrams—macromolecular components in interaction—in the context of genomic complements. The book also features: A solid, comprehensive treatment of phylogenomics, the evolution of genomes, and the evolution of biological networks, within the framework of systems biology A special section on RNA biology—translation, evolution of structure, and micro RNA and regulation of gene expression Chapters on the mapping of genotypes to phenotypes, the role of information in biology, protein architecture and biological function, chromosomal rearrangements, and biological networks and disease Contributions by leading authorities on each topic Evolutionary Genomics and Systems Biology is an ideal book for students and professionals in genomics, bioinformatics, evolution, structural biology, complexity, origins of life, systematic biology, and organismal diversity, as well as those individuals interested in aspects of biological sciences as they interface with chemistry, physics, and computer science and engineering.
Author : Daniel W. McShea,Robert N. Brandon Publisher : University of Chicago Press Page : 186 pages File Size : 49,5 Mb Release : 2010-07-15 Category : Science ISBN : 9780226562278
Biology's First Law by Daniel W. McShea,Robert N. Brandon Pdf
Life on earth is characterized by three striking phenomena that demand explanation: adaptation—the marvelous fit between organism and environment; diversity—the great variety of organisms; and complexity—the enormous intricacy of their internal structure. Natural selection explains adaptation. But what explains diversity and complexity? Daniel W. McShea and Robert N. Brandon argue that there exists in evolution a spontaneous tendency toward increased diversity and complexity, one that acts whether natural selection is present or not. They call this tendency a biological law—the Zero-Force Evolutionary Law, or ZFEL. This law unifies the principles and data of biology under a single framework and invites a reconceptualization of the field of the same sort that Newton’s First Law brought to physics. Biology’s First Law shows how the ZFEL can be applied to the study of diversity and complexity and examines its wider implications for biology. Intended for evolutionary biologists, paleontologists, and other scientists studying complex systems, and written in a concise and engaging format that speaks to students and interdisciplinary practitioners alike, this book will also find an appreciative audience in the philosophy of science.
Creative Evolutionary Systems by Peter Bentley,David W. Corne Pdf
Written for computer scientists and students, and computer literate artists, designers and specialists in evolutionary computation, this text brings together the most advanced work in the use of evolutionary computation for creative results.
Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics by Elena Marchiori Pdf
This book constitutes the refereed proceedings of the 5th European Conference on Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics, EvoBIO 2007, held in Valencia, Spain, April 2007. Coverage brings together experts in computer science with experts in bioinformatics and the biological sciences. It presents contributions on fundamental and theoretical issues along with papers dealing with different applications areas.
Evolutionary Biology—A Transdisciplinary Approach by Pierre Pontarotti Pdf
This book includes 16 selected contributions presented at the 23rd Evolutionary Biology Meeting, which took place in Marseille in September 2019. The annual Evolutionary Biology Meetings in Marseille serve to gather leading evolutionary biologists and other scientists using evolutionary biology concepts, e.g. for medical research. The aim of these meetings is to promote the exchange of ideas to encourage interdisciplinary collaborations. Offering an up-to-date overview of recent findings in the field of evolutionary biology, this book is an invaluable source of information for scientists, teachers and advanced students.
Principles of Evolution covers all aspects of the subject. Following an introductory section that provides necessary background, it has chapters on the evidence for evolution that cover the fossil record, DNA-sequence homologies, and protein homologies (evo-devo). It also includes a full history of life from the first universal common ancestor, through the rise of the eukaryote and on to the major groups of phyla. This section is followed by one on the mechanism of evolution with chapters on variation, selection and speciation. The main part of the book ends with a chapter on human evolution and this is followed by appendices that expand on the making of fossils, the history of the subject and creationism. What marks this book as different from others on evolution is its systems-biology perspective. This new area focuses on the role of protein networks and on multi-level complexity, and is used in three contexts. First, most biological activity is driven by such networks and this has direct implications for understanding evo-devo and for seeing how variation is initiated, mainly during embryogenesis. Second, it provides the natural language for discussing phylogenetics. Third, evolutionary change involves events at levels ranging from the genome to the ecosystem and systems biology provides a context for integrating material of this complexity. The book assumes a basic grounding in biology but little mathematics as the difficult subject of evolutionary population genetics is mainly covered qualitatively, with major results being discussed and used rather than derived. Principles of Evolution will be an interesting and thought-provoking text for undergraduates and graduates across the biological sciences.
An Introduction to Systems Biology by Uri Alon Pdf
Thorough and accessible, this book presents the design principles of biological systems, and highlights the recurring circuit elements that make up biological networks. It provides a simple mathematical framework which can be used to understand and even design biological circuits. The textavoids specialist terms, focusing instead on several well-studied biological systems that concisely demonstrate key principles. An Introduction to Systems Biology: Design Principles of Biological Circuits builds a solid foundation for the intuitive understanding of general principles. It encourages the reader to ask why a system is designed in a particular way and then proceeds to answer with simplified models.
Plant Systems Biology by Sacha Baginsky,Alisdair R. Fernie Pdf
This volume aims to provide a timely view of the state-of-the-art in systems biology. The editors take the opportunity to define systems biology as they and the contributing authors see it, and this will lay the groundwork for future studies. The volume is well-suited to both students and researchers interested in the methods of systems biology. Although the focus is on plant systems biology, the proposed material could be suitably applied to any organism.
Evolutionary Systems by G. Vijver,Stanley N. Salthe,M. Delpos Pdf
The three well known revolutions of the past centuries - the Copernican, the Darwinian and the Freudian - each in their own way had a deflating and mechanizing effect on the position of humans in nature. They opened up a richness of disillusion: earth acquired a more modest place in the universe, the human body and mind became products of a long material evolutionary history, and human reason, instead of being the central, immaterial, locus of understanding, was admitted into the theater of discourse only as a materialized and frequently out-of-control actor. Is there something objectionable to this picture? Formulated as such, probably not. Why should we resist the idea that we are in certain ways, and to some degree, physically, biologically or psychically determined? Why refuse to acknowledge the fact that we are materially situated in an ever evolving world? Why deny that the ways of inscription (traces of past events and processes) are co-determinative of further "evolutionary pathways"? Why minimize the idea that each intervention, of each natural being, is temporally and materially situated, and has, as such, the inevitable consequence of changing the world? The point is, however, that there are many, more or less radically different, ways to consider the "mechanization" of man and nature. There are, in particular, many ways to get the message of "material and evolutionary determination", as well as many levels at which this determination can be thought of as relevant or irrelevant.
Encyclopedia of Evolutionary Biology by Anonim Pdf
Encyclopedia of Evolutionary Biology, Four Volume Set is the definitive go-to reference in the field of evolutionary biology. It provides a fully comprehensive review of the field in an easy to search structure. Under the collective leadership of fifteen distinguished section editors, it is comprised of articles written by leading experts in the field, providing a full review of the current status of each topic. The articles are up-to-date and fully illustrated with in-text references that allow readers to easily access primary literature. While all entries are authoritative and valuable to those with advanced understanding of evolutionary biology, they are also intended to be accessible to both advanced undergraduate and graduate students. Broad topics include the history of evolutionary biology, population genetics, quantitative genetics; speciation, life history evolution, evolution of sex and mating systems, evolutionary biogeography, evolutionary developmental biology, molecular and genome evolution, coevolution, phylogenetic methods, microbial evolution, diversification of plants and fungi, diversification of animals, and applied evolution. Presents fully comprehensive content, allowing easy access to fundamental information and links to primary research Contains concise articles by leading experts in the field that ensures current coverage of each topic Provides ancillary learning tools like tables, illustrations, and multimedia features to assist with the comprehension process
Evolutionary Theory by Niles Eldredge,Telmo Pievani,Emanuele Serrelli,Ilya Tëmkin Pdf
The natural world is infinitely complex and hierarchically structured, with smaller units forming the components of progressively larger systems: molecules make up cells, cells comprise tissues and organs that are, in turn, parts of individual organisms, which are united into populations and integrated into yet more encompassing ecosystems. In the face of such awe-inspiring complexity, there is a need for a comprehensive, non-reductionist evolutionary theory. Having emerged at the crossroads of paleobiology, genetics, and developmental biology, the hierarchical approach to evolution provides a unifying perspective on the natural world and offers an operational framework for scientists seeking to understand the way complex biological systems work and evolve. Coedited by one of the founders of hierarchy theory and featuring a diverse and renowned group of contributors, this volume provides an integrated, comprehensive, cutting-edge introduction to the hierarchy theory of evolution. From sweeping historical reviews to philosophical pieces, theoretical essays, and strictly empirical chapters, it reveals hierarchy theory as a vibrant field of scientific enterprise that holds promise for unification across the life sciences and offers new venues of empirical and theoretical research. Stretching from molecules to the biosphere, hierarchy theory aims to provide an all-encompassing understanding of evolution and—with this first collection devoted entirely to the concept—will help make transparent the fundamental patterns that propel living systems.
Modeling Methods for Medical Systems Biology by María Elena Álvarez-Buylla Roces,Juan Carlos Martínez-García,José Dávila-Velderrain,Elisa Domínguez-Hüttinger,Mariana Esther Martínez-Sánchez Pdf
This book contributes to better understand how lifestyle modulations can effectively halt the emergence and progression of human diseases. The book will allow the reader to gain a better understanding of the mechanisms by which the environment interferes with the bio-molecular regulatory processes underlying the emergence and progression of complex diseases, such as cancer. Focusing on key and early cellular bio-molecular events giving rise to the emergence of degenerative chronic disease, it builds on previous experience on the development of multi-cellular organisms, to propose a mathematical and computer based framework that allows the reader to analyze the complex interplay between bio-molecular processes and the (micro)-environment from an integrative, mechanistic, quantitative and dynamical perspective. Taking the wealth of empirical evidence that exists it will show how to build and analyze models of core regulatory networks involved in the emergence and progression of chronic degenerative diseases, using a bottom-up approach.
