Excitation Contraction Coupling In Skeletal Cardiac And Smooth Muscle

Author : George B. Frank,C. Paul Bianchi,Henk Keurs
Publisher : Springer Science & Business Media
Page : 450 pages
File Size : 42,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461533627

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Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle by George B. Frank,C. Paul Bianchi,Henk Keurs Pdf

The Third International Symposium on Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle, organized by George Frank, C. Paul Bianchi, and Henk E. DJ. ter Keurs, was held in Banff Centre, Banff, Alberta, Canada during June 26 to June 30, 1991. The theme of these symposia has been to recognize the similarities and dissimilarities of excitation-contraction coupling in skeletal, cardiac, and smooth muscle. Cross fertilization of concepts of excitation-contraction coupling in these three types of muscle has occurred since the early studies in the late fifties and early sixties on skeletal muscle. Investigators in each field meet only at specialized symposia which exclude investigators in the other fields. The purpose of the symposia has been to bring together international investigators studying excitation-contraction coupling in skeletal, cardiac, and smooth muscle so that we may learn from each other and hence provide a more global concept of excitation-contraction. The Third International Symposia has accomplished its objective as we recognize that calcium channels of the sarcolemma and the sarcoplasmic reticulum play key essential roles in excitation-contraction coupling in all three types of muscles. In skeletal muscle the recognition that E-C coupling consists of two parallel mechanisms, one dependent upon a dihydropyridine voltage-sensitive sensors coupled to calcium release from the terminal cisternae via the ryanodine sensitive channel in the foot structure of the triad.

Author : Anonim
Publisher : Unknown
Page : 0 pages
File Size : 54,7 Mb
Release : 1982
Category : Electronic
ISBN : OCLC:499480529

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Excitation-contraction Coupling in Skeletal, Cardiac and Smooth Muscle by Anonim Pdf

Author : Anonim
Publisher : Unknown
Page : 174 pages
File Size : 40,9 Mb
Release : 1982
Category : Electronic
ISBN : OCLC:923075974

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Excitation-contraction Coupling in Skeletal, Cardiac and Smooth Muscle by Anonim Pdf

Author : Donald Bers
Publisher : Springer Science & Business Media
Page : 427 pages
File Size : 47,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401006583

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Excitation-Contraction Coupling and Cardiac Contractile Force by Donald Bers Pdf

How is the heartbeat generated? What controls the strength of contraction of heart muscle? What are the links between cardiac structure and function? How does our understanding of skeletal and smooth muscle and non-muscle cells influence our thinking about force development in the heart? Are there important species differences in how contraction is regulated in the heart? How do the new molecular data fit together in understanding the heart beat? What goes wrong in ischemia, hypertrophy, and heart failure? This book paints a modern `portrait' of how the heart works and in this picture the author shows a close-up of the structural, biochemical, and physiological links between excitation and contraction. The author takes the reader through a series of important, interrelated topics with great clarity and continuity and also includes many useful illustrations and tables. The book starts by considering the cellular structures involved in excitation-contraction coupling and then described the characteristics of the myofilaments as the end effector of excitation-contraction coupling. A general scheme of calcium regulation is described and the possible sources and sinks of calcium are discussed in simple, but quantitative terms. The cardiac action potential and its many underlying currents are reviewed. Then the characteristics of some key calcium transport systems (calcium channels, sodium/calcium exchange and SR calcium uptake and release) are discussed in detail. This is then built into a more integrated picture of calcium regulation in succeeding chapters by detailed discussions of excitation-calcium coupling mechanisms (in skeletal, cardiac, and smooth muscle), the interplay between calcium regulatory processes, and finally mechanisms of cardiac inotropy, calcium overload, and dysfunction (e.g., ischemia, hypertrophy, and heart failure). Excitation-Contraction Coupling and Cardiac Contractile Force – Second Edition is an invaluable source of information for anyone who is interested in how the heart beat is controlled and especially suited for students of the cardiovascular system at all levels from medical/graduate students through senior investigators in related fields.

Author : T. B. Bolton,T. Tomita
Publisher : Unknown
Page : 568 pages
File Size : 43,7 Mb
Release : 1996
Category : Medical
ISBN : UOM:39015038154343

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Smooth Muscle Excitation by T. B. Bolton,T. Tomita Pdf

This book is a compendium of the latest electrophysiological research on smooth muscles from an international collection of authors. It includes recent discoveries in calcium stores and their relationship to contraction and to electrical changes in the membrane. A major section of the book concentrates on calcium release mechanisms in the cell, their control, and the consequences of calcium release in the cell for membrane events. Smooth Muscle Excitation also covers the effects of chemicals released from adjacent cells. Key Features * State-of-the-art volume that represents a synopsis of all work currently being undertaken in this area throughout the world * Content covers both basic and clinical research * Provides a range of drug development studies * Presents contributions from many internationally recognized smooth muscle physiologists

Author : R. D. Keynes,D. J. Aidley
Publisher : Cambridge University Press
Page : 196 pages
File Size : 49,7 Mb
Release : 2001-03-15
Category : Medical
ISBN : 0521805848

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Nerve and Muscle by R. D. Keynes,D. J. Aidley Pdf

Essential textbook for all undergraduate students of neurobiology, physiology, cell biology and preclinical medicine.

Author : Christopher L.-H. Huang
Publisher : Cambridge University Press
Page : 327 pages
File Size : 45,6 Mb
Release : 2020-11-19
Category : Medical
ISBN : 9781108495059

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Keynes & Aidley's Nerve and Muscle by Christopher L.-H. Huang Pdf

Editions previous to this one had R.D. Keynes and David J. Aidley as primary and secondary authors.

Author : Lindsay Biga,Devon Quick,Sierra Dawson,Amy Harwell,Robin Hopkins,Joel Kaufmann,Mike LeMaster,Philip Matern,Katie Morrison-Graham,Jon Runyeon
Publisher : Unknown
Page : 128 pages
File Size : 43,6 Mb
Release : 2019-09-26
Category : Electronic
ISBN : 1955101159

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Anatomy & Physiology by Lindsay Biga,Devon Quick,Sierra Dawson,Amy Harwell,Robin Hopkins,Joel Kaufmann,Mike LeMaster,Philip Matern,Katie Morrison-Graham,Jon Runyeon Pdf

A version of the OpenStax text

Author : Colin Pinnock,Ted Lin,Robert Jones,Tim Smith
Publisher : Cambridge University Press
Page : 990 pages
File Size : 53,8 Mb
Release : 2002-12
Category : Medical
ISBN : 052169079X

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Fundamentals of Anaesthesia by Colin Pinnock,Ted Lin,Robert Jones,Tim Smith Pdf

The second edition of Fundamentals of Anaesthesia builds upon the success of the first edition, and encapsulates the modern practice of anaesthesia in a single volume. Written and edited by a team of expert contributors, it provides a comprehensive but easily readable account of all of the information required by the FRCA Primary examination candidate and has been expanded to include more detail on all topics and to include new topics now covered in the examination. As with the previous edition, presentation of information is clear and concise, with the use of lists, tables, summary boxes and line illustrations where necessary to highlight important information and aid the understanding of complex topics. Great care has been taken to ensure an unrivalled consistency of style and presentation throughout.

Author : J. Gordon Betts,Peter DeSaix,Jody E. Johnson,Oksana Korol,Dean H. Kruse,Brandon Poe,James A. Wise,Mark Womble,Kelly A. Young
Publisher : Unknown
Page : 0 pages
File Size : 51,7 Mb
Release : 2013-04-25
Category : Electronic
ISBN : 1947172808

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Anatomy and Physiology by J. Gordon Betts,Peter DeSaix,Jody E. Johnson,Oksana Korol,Dean H. Kruse,Brandon Poe,James A. Wise,Mark Womble,Kelly A. Young Pdf

Author : David Chambers,Christopher Huang,Gareth Matthews
Publisher : Cambridge University Press
Page : 469 pages
File Size : 50,8 Mb
Release : 2019-07-25
Category : Medical
ISBN : 9781108463997

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Basic Physiology for Anaesthetists by David Chambers,Christopher Huang,Gareth Matthews Pdf

Easily understood, up-to-date and clinically relevant, this book provides junior anaesthetists with an essential physiology resource.

Author : Frank C. Mooren
Publisher : Springer
Page : 0 pages
File Size : 40,6 Mb
Release : 2012-04-19
Category : Medical
ISBN : 3540360654

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Encyclopedia of Exercise Medicine in Health and Disease by Frank C. Mooren Pdf

The Encyclopedia of Exercise Medicine is intelligently structured, easy accessible and user-friendly: A-Z format, clear, concise language and uniform essay structure as well as extensive cross references between keywords and related articles enables efficient searches in a user-friendly manner both for experts and newcomers. It is intended to be a comprehensive up-to-date data base on the adaptation of the human body to exercise and on the therapeutic use of exercise with up to 2,000 keywords. It covers all aspects within the full range of modern exercise medicine of each particular scientific discipline (cancer, parasitology, aging, etc.). This includes information on methodological approaches to measuring the principle components of motor fitness, and practical aspects of their enhancement by trainings regimes as well as by nutrition and the application of drugs. Such a wide range of entries, all written by leading experts in their respective fields, will therefore address both the basic/clinical scientist as well as the practitioner. Moreover, the Encyclopedia of Exercise Medicine is aimed at people in related fields, health care professionals, physiotherapists, trainers, students, informed athletes and interested laypersons. It is available both in print and as a fully searchable and hyperlinked electronic online edition.

Author : Andreas Rummel,Thomas Binz
Publisher : Springer Science & Business Media
Page : 322 pages
File Size : 40,8 Mb
Release : 2012-12-14
Category : Medical
ISBN : 9783642335709

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Botulinum Neurotoxins by Andreas Rummel,Thomas Binz Pdf

The extremely potent substance botulinum neurotoxin (BoNT) has attracted much interest in diverse fields. Originally identified as cause for the rare but deadly disease botulism, military and terrorist intended to misuse this sophisticated molecule as biological weapon. This caused its classification as select agent category A by the Centers for Diseases Control and Prevention and the listing in the Biological and Toxin Weapons Convention. Later, the civilian use of BoNT as long acting peripheral muscle relaxant has turned this molecule into an indispensable pharmaceutical world wide with annual revenues >$1.5 billion. Also basic scientists value the botulinum neurotoxin as molecular tool for dissecting mechanisms of exocytosis. This book will cover the most recent molecular details of botulinum neurotoxin, its mechanism of action as well as its detection and application.

Author : R. Casteels,Théophile Godfraind,Johann Caspar Rüegg
Publisher : North-Holland
Page : 512 pages
File Size : 48,9 Mb
Release : 1977
Category : Nature
ISBN : UOM:39015004413673

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Excitation-contraction Coupling in Smooth Muscle by R. Casteels,Théophile Godfraind,Johann Caspar Rüegg Pdf

Author : Jonathan H. Mackay,Joseph E. Arrowsmith
Publisher : Cambridge University Press
Page : 0 pages
File Size : 42,9 Mb
Release : 2012-03-15
Category : Medical
ISBN : 052119685X

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Core Topics in Cardiac Anesthesia by Jonathan H. Mackay,Joseph E. Arrowsmith Pdf

Since the publication of the first edition of Core Topics in Cardiac Anaesthesia, the clinical landscape has undergone significant change. Recent developments include the increased use of electrophysiology, the resurgence of primary percutaneous intervention in acute coronary syndromes, the use of percutaneous devices in patients previously considered inoperable, and the withdrawal of aprotinin. Against this landscape, this invaluable resource has been fully updated. New chapters are dedicated to right heart valves, pulmonary vascular disease, cardiac tumours and cardiac trauma. All other chapters have been updated according to the latest international guidelines. Written and edited by an international author team with a wealth of expertise in all aspects of the perioperative care of cardiac patients, topics are presented in an easy to digest and a readily accessible manner. Core Topics in Cardiac Anaesthesia, Second Edition is essential reading for residents and fellows in anaesthesia and cardiac surgery and clinical perfusionists.