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Author : Stanley E. Lazic
Publisher : Cambridge University Press
Page : 429 pages
File Size : 48,8 Mb
Release : 2016-12-08
Category : Family & Relationships
ISBN : 9781107074293
A guide to designing lab-based biological experiments that have low bias, high precision and widely applicable results.
Author : David J. Glass
Publisher : CSHL Press
Page : 211 pages
File Size : 48,9 Mb
Release : 2007
Category : Biology
ISBN : 9780879697358
The effective design of scientific experiments is critical to success, yet graduate students receive very little formal training in how to do it. Based on a well-received course taught by the author, Experimental Design for Biologistsfills this gap. Experimental Design for Biologistsexplains how to establish the framework for an experimental project, how to set up a system, design experiments within that system, and how to determine and use the correct set of controls. Separate chapters are devoted to negative controls, positive controls, and other categories of controls that are perhaps less recognized, such as “assumption controls†and “experimentalist controls†. Furthermore, there are sections on establishing the experimental system, which include performing critical “system controls†. Should all experimental plans be hypothesis-driven? Is a question/answer approach more appropriate? What was the hypothesis behind the Human Genome Project? What color is the sky? How does one get to Carnegie Hall? The answers to these kinds of questions can be found in Experimental Design for Biologists. Written in an engaging manner, the book provides compelling lessons in framing an experimental question, establishing a validated system to answer the question, and deriving verifiable models from experimental data. Experimental Design for Biologistsis an essential source of theory and practical guidance in designing a research plan.
Author : Gerald Peter Quinn,Michael J. Keough
Publisher : Cambridge University Press
Page : 560 pages
File Size : 53,5 Mb
Release : 2002-03-21
Category : Mathematics
ISBN : 0521009766
Regression, analysis of variance, correlation, graphical.
Author : Graeme D. Ruxton,Nick Colegrave
Publisher : Unknown
Page : 0 pages
File Size : 40,9 Mb
Release : 2023
Category : Experimental design
ISBN : 0191975206
Providing students with clear and practical advice on how best to organise experiments and collect data so as to make the subsequent analysis easier and their conclusions more robust, this text assumes no specialist knowledge.
Author : Bruno J. Strasser
Publisher : University of Chicago Press
Page : 421 pages
File Size : 51,7 Mb
Release : 2019-06-07
Category : Technology & Engineering
ISBN : 9780226635187
Databases have revolutionized nearly every aspect of our lives. Information of all sorts is being collected on a massive scale, from Google to Facebook and well beyond. But as the amount of information in databases explodes, we are forced to reassess our ideas about what knowledge is, how it is produced, to whom it belongs, and who can be credited for producing it. Every scientist working today draws on databases to produce scientific knowledge. Databases have become more common than microscopes, voltmeters, and test tubes, and the increasing amount of data has led to major changes in research practices and profound reflections on the proper professional roles of data producers, collectors, curators, and analysts. Collecting Experiments traces the development and use of data collections, especially in the experimental life sciences, from the early twentieth century to the present. It shows that the current revolution is best understood as the coming together of two older ways of knowing—collecting and experimenting, the museum and the laboratory. Ultimately, Bruno J. Strasser argues that by serving as knowledge repositories, as well as indispensable tools for producing new knowledge, these databases function as digital museums for the twenty-first century.
Author : Steve McKillup
Publisher : Cambridge University Press
Page : 430 pages
File Size : 43,5 Mb
Release : 2011-11-03
Category : Medical
ISBN : 9781139502948
An understanding of statistics and experimental design is essential for life science studies, but many students lack a mathematical background and some even dread taking an introductory statistics course. Using a refreshingly clear and encouraging reader-friendly approach, this book helps students understand how to choose, carry out, interpret and report the results of complex statistical analyses, critically evaluate the design of experiments and proceed to more advanced material. Taking a straightforward conceptual approach, it is specifically designed to foster understanding, demystify difficult concepts and encourage the unsure. Even complex topics are explained clearly, using a pictorial approach with a minimum of formulae and terminology. Examples of tests included throughout are kept simple by using small data sets. In addition, end-of-chapter exercises, new to this edition, allow self-testing. Handy diagnostic tables help students choose the right test for their work and remain a useful refresher tool for postgraduates.
Author : Jenny E. Sabin,Peter Lloyd Jones (Spatial biologist)
Publisher : Unknown
Page : 0 pages
File Size : 43,7 Mb
Release : 2018
Category : Architecture and biology
ISBN : 113878396X
Cover -- Half Title -- Title Page -- Copyright Page -- Table of Contents -- Preface -- Foreword: Reinventing Nature -- Acknowledgments -- Part I Design Research in Practice: Methodology and Approach with Historical Precedents and Case Studies -- 1 Bioconstructivisms -- Trans-Disciplinary Research Practice: Contemporary Case Studies -- 2 Design Research in Practice: A New Model -- Part II Design Computation Tools for Architecture and Science: New Tools and Forms -- Introduction to Design Computation Tools for Architecture and Science: New Tools and Forms -- 3 Networking: Elasticity and Branching Morphogenesis -- Comments on the Role of the Matrix -- New Architectural Concerns -- 4 Motility: Adaptive Architecture and Personalized Medicine -- Topologically Free Cells -- Avoiding Biomimicry -- Visualizing in Another Dimension -- Positioning Mechanism -- Newness -- 5 Surface Design: The Mammary Gland as a Model of Architectural Connectivity -- On Geometry and Cellular Mechanics -- Biological Data and Intuition -- Case Study: Understanding Behavioral Rule Sets through Cell Motility -- Case Study: Motility and the Observation of Change -- Case Study: Microfabrication: Spatializing Cell Signaling and Sensing Mechanisms -- 6 BioInspired Materials and Design -- Part III Architectural Prototyping: Human-Scale Material Systems and Big Datascapes -- 7 The New Science of Making -- 8 Matter Design Computation: Biosynthesis and New Paradigms of Making -- Project: Branching Morphogenesis, 2008 -- Project: Ground Substance, 2009 -- Workshop: Nonlinear Systems Biology and Design, 2010 -- Part IV Personalized Architecture and Medicine -- 9 eSkin: BioInspired Adaptive Materials -- 10 myThread Pavilion -- Interview: RE(IN)FORM(ULAT)ING Health Care via Medicine + Creativity -- Conclusion -- Notes on Contributors -- Image Credits -- Index
Author : Robert E. Kohler
Publisher : University of Chicago Press
Page : 341 pages
File Size : 55,6 Mb
Release : 2010-11-15
Category : Science
ISBN : 9780226450117
What is it like to do field biology in a world that exalts experiments and laboratories? How have field biologists assimilated laboratory values and practices, and crafted an exact, quantitative science without losing their naturalist souls? In Landscapes and Labscapes, Robert E. Kohler explores the people, places, and practices of field biology in the United States from the 1890s to the 1950s. He takes readers into the fields and forests where field biologists learned to count and measure nature and to read the imperfect records of "nature's experiments." He shows how field researchers use nature's particularities to develop "practices of place" that achieve in nature what laboratory researchers can only do with simplified experiments. Using historical frontiers as models, Kohler shows how biologists created vigorous new border sciences of ecology and evolutionary biology.
Author : S.J. Welham,S.A. Gezan,S.J. Clark,A. Mead
Publisher : CRC Press
Page : 592 pages
File Size : 43,8 Mb
Release : 2014-08-22
Category : Mathematics
ISBN : 9781439898055
Written in simple language with relevant examples, Statistical Methods in Biology: Design and Analysis of Experiments and Regression is a practical and illustrative guide to the design of experiments and data analysis in the biological and agricultural sciences. The book presents statistical ideas in the context of biological and agricultural scien
Author : Jane Roskams,Linda Rodgers,Albert S. Mellick
Publisher : CSHL Press
Page : 259 pages
File Size : 46,7 Mb
Release : 2002
Category : Biochemistry
ISBN : 9780879698157
"The first Lab Ref volume compiled recipes and reference data drawn from a selection of our manuals and was intended to save time and spare frustration." ... "In the same spirit, Lab Ref 2 again assembles in one place a new selection of reference information that should maximize the volume's value in a crowded laboratory environment."--Note.
Author : Martina Bremer,Rebecca W. Doerge
Publisher : Unknown
Page : 0 pages
File Size : 52,5 Mb
Release : 2015
Category : Bioinformatics
ISBN : 1621821129
Using R at the Bench: Step-by-Step Data Analytics for Biologists is a convenient bench-side handbook for biologists, designed as a handy reference guide for elementary and intermediate statistical analyses using the free/public software package known as "R." The expectations for biologists to have a more complete understanding of statistics are growing rapidly. New technologies and new areas of science, such as microarrays, next-generation sequencing, and proteomics, have dramatically increased the need for quantitative reasoning among biologists when designing experiments and interpreting results. Even the most routine informatics tools rely on statistical assumptions and methods that need to be appreciated if the scientific results are to be correct, understood, and exploited fully. Although the original Statistics at the Bench is still available for sale and has all examples in Excel, this new book uses the same text and examples in R. A new chapter introduces the basics of R: where to download, how to get started, and some basic commands and resources. There is also a new chapter that explains how to analyze next-generation sequencing data using R (specifically, RNA-Seq). R is powerful statistical software with many specialized packages for biological applications and Using R at the Bench: Step-by-Step Data Analytics for Biologists is an excellent resource for those biologists who want to learn R. This handbook for working scientists provides a simple refresher for those who have forgotten what they once knew and an overview for those wishing to use more quantitative reasoning in their research. Statistical methods, as well as guidelines for the interpretation of results, are explained using simple examples. Throughout the book, examples are accompanied by detailed R commands for easy reference.
Author : Jean Dickey
Publisher : Benjamin-Cummings Publishing Company
Page : 546 pages
File Size : 50,9 Mb
Release : 1995
Category : Science
ISBN : 0805309225
An investigative approach actively involves students in the process of scientific discovery by allowing them to make observations, devise techniques, and draw conclusions. Twenty carefully chosen laboratory topics encourage students to use their critical thinking skills to solve problems using the scientific method.
Author : Stephen J. Royle
Publisher : Unknown
Page : 200 pages
File Size : 47,6 Mb
Release : 2019
Category : Science
ISBN : 1621822788
"Cell biology is becoming an increasingly quantitative field, as technical advances mean researchers now routinely capture vast amounts of data. This handbook is an essential guide to the computational approaches, image processing and analysis techniques, and basic programming skills that are now part of the skill set of anyone working in the field"--
Author : National Research Council,Institute of Medicine,Institute for Laboratory Animal Research,Commission on Life Sciences,Committee on the Use of Laboratory Animals in Biomedical and Behavioral Research
Publisher : National Academies Press
Page : 113 pages
File Size : 47,8 Mb
Release : 1988-02-01
Category : Science
ISBN : 9780309038393
Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.
Author : Marta Bertolaso
Publisher : Routledge
Page : 248 pages
File Size : 53,7 Mb
Release : 2015-10-06
Category : History
ISBN : 9781317316848
Focusing on cell dynamics, molecular medicine and robotics, contributors explore the interplay between biological, technological and theoretical ways of thinking. The collection makes a strong contribution to current debates in the philosophy of science and the changing role of scientific practice.
