Experimental Organic Medicinal Chemistry

Author : N. Swathi,T Durai Ananda Kumar
Publisher : Unknown
Page : 472 pages
File Size : 40,8 Mb
Release : 2016-09-27
Category : Science
ISBN : 9352300793

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Experimental Organic & Medicinal Chemistry by N. Swathi,T Durai Ananda Kumar Pdf

The modern medicinal chemistry utilizes several novel drug discovery tools to identify the drug-like molecules (lead) and to convert them into therapeutically potential molecules. The advanced and adequate practice in synthetic medicinal chemistry is essential for pharmacy graduates (B. Pharmacy and M. Pharmacy) to receive recognition in academia and industry sectors. This book titled Experimental Organic and Medicinal Chemistry-Principles & Practice consists of several topics covering both theory and practical concepts. The material spreads into synthetic and analytical approaches. The synthetic approach includes synthesis of drugs and drug intermediates and green synthetic strategy. The analytical approach deals with estimations of drugs, qualitative analysis of inorganic, organic and natural products, isolation and determination of active principles from natural sources. In addition, safety measurements, general laboratory practices, preparation of a few solutions and reagents are included as a ready reference. This book is a good companion for students of B. Pharmacy and a source book for M. Pharmacy (Pharmaceutical chemistry, Medicinal Chemistry) and other Pharmaceutical and medicinal chemistry disciplines. Salient features of this book are Systematic descriptions in simple language. Neat and self explanatory chemical reaction mechanisms. The role of reagents, alternative reagents and hazards associated are highlighted. Pharmaceutical relevance of chemical reactions are described. Limit tests, qualitative analysis of inorganic, natural and synthetic organic compounds are described in a lucid manner. Estimations of natural and organic-medicinal compounds along with isolation of active principles are discussed.

Author : Surya K. De
Publisher : John Wiley & Sons
Page : 856 pages
File Size : 53,5 Mb
Release : 2021-03-08
Category : Science
ISBN : 9783527347858

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Applied Organic Chemistry by Surya K. De Pdf

An indispensable guide for all synthetic chemists who want to learn about the most relevant reactions and reagents employed to synthesize important heterocycles and drugs! The synthesis of natural products, bioactive compounds, pharmaceuticals, and drugs is of fundamental interest in modern organic chemistry. New reagents and reaction methods towards these molecules are being constantly developed. By understanding the mechanisms involved and scope and limitations of each reaction applied, organic chemists can further improve existing reaction protocols and develop novel efficient synthetic routes towards frequently used drugs, such as Aspirin or Penicillin. Applied Organic Chemistry provides a summary of important (name) reactions and reagents applied in modern organic chemistry and drug synthesis. It covers rearrangement, condensation, olefination, metathesis, aromatic electrophilic substitutions, Pd-catalyzed C-C bond forming reactions, multi-component reactions, as well as oxidations and reductions. Each chapter is clearly structured, providing valuable information on reaction details, step-by-step mechanism, experimental procedures, applications, and (patent) references. By providing mechanistic information and representative experimental procedures, this book is an indispensable guide for researchers and professionals in organic chemistry, natural product synthesis, pharmaceutical, and medicinal chemistry, as well as post-graduates preparing themselves for a job in the pharmaceutical industry. Hot Topic: Reviews important classes of organic reactions (incl. name reactions) and reagents in medicinal chemistry. Useful: Provides information on reaction details, common reagents, and functional group transformations used to synthesize natural products, bioactive compounds, drugs, and pharmaceuticals, e.g. Aspirin, Penicillin. Unique: For every reaction the mechanism is explained step by step, and representative experimental procedures are given, unlike most books in this area. User-friendly: Chapters are clearly structured making it easy for the reader to compare different reactions. Applied Organic Chemistry is an indispensable guide for researchers and professionals in organic chemistry, natural product synthesis, pharmaceutical, and medicinal chemistry, as well as post-graduates preparing themselves for a job in the pharmaceutical industry.

Author : Laurence M. Harwood,Christopher J. Moody
Publisher : Wiley-Blackwell
Page : 778 pages
File Size : 47,9 Mb
Release : 1989-01
Category : Science
ISBN : 0632020164

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Experimental Organic Chemistry by Laurence M. Harwood,Christopher J. Moody Pdf

Author : Charles Dickson
Publisher : CRC Press
Page : 160 pages
File Size : 46,6 Mb
Release : 2014-02-21
Category : Medical
ISBN : 9781482225105

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Experiments in Pharmaceutical Chemistry by Charles Dickson Pdf

Written by an author with more than 40 years of teaching experience in the field, Experiments in Pharmaceutical Chemistry, Second Edition responds to a critical classroom need for material on directed laboratory investigations in biological and pharmaceutical chemistry. This new edition supplies 75 experiments, expanding the range of topics to 22 m

Author : Anees Ahmad Siddiqui
Publisher : CBS Publishers & Distributors Private Limited
Page : 9 pages
File Size : 53,8 Mb
Release : 2024-07-01
Category : Electronic
ISBN : 9789387085145

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ORGANIC MEDICINAL CHEMISTRY PRACTICAL MANUAL FOR PHARMACY AND SCIENCE STUDENTS by Anees Ahmad Siddiqui Pdf

The manual illustrates the concept of basic techniques in practical organic medicinal chemistry. It aims to meet the requirements of B Pharmacy students under the new syllabus prescribed by Pharmacy Council of India. It will also be useful to BSc, BSc (Hons) and MSc medicinal chemistry students.

Author : Prasenjit Mondal,Sumanta Mondal
Publisher : Educreation Publishing
Page : 262 pages
File Size : 50,5 Mb
Release : 2019-02-20
Category : Education
ISBN : 8210379456XXX

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Handbook of Practical Pharmaceutical Organic, Inorganic and Medicinal Chemistry by Prasenjit Mondal,Sumanta Mondal Pdf

This book described about the concept and procedure involved in various important inorganic laboratory experiments, with all the possible explanation. This book explains about the detail’s steps involved the identification of unknown chemical compounds, synthesis of numbers of drugs and intermediates with reaction mechanisms and calculation. The assay methods of various drugs and calculation of drug content also included. This book covers the entire inorganic, organic and medicinal chemistry experiments as per the Pharmacy council of India’s B. Pharm and Pharm D syllabus

Author : Tahmeena Khan,Abdul Rahman Khan,Saman Raza,Iqbal Azad,Alfred J. Lawrence
Publisher : Bentham Science Publishers
Page : 270 pages
File Size : 52,6 Mb
Release : 2021-09-02
Category : Science
ISBN : 9789814998284

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Medicinal and Environmental Chemistry: Experimental Advances and Simulations (Part I) by Tahmeena Khan,Abdul Rahman Khan,Saman Raza,Iqbal Azad,Alfred J. Lawrence Pdf

Medicinal and Environmental Chemistry: Experimental Advances and Simulations is a collection of topics that highlight the use of pharmaceutical chemistry to assess the environment or make drug design and chemical testing more environment friendly. The ten chapters included in the first part of this book set cover diverse topics, blending the fields of environmental chemistry and medicinal chemistry and have been authored by experts, scientists and academicians from renowned institutions. The book introduces the reader to environmental contaminants and techniques for their quantification and removal. A medicinal perspective for effects and remediation of environmental hazards, and therapeutic strategies available to design new and safer drugs, is addressed with a focus on knowledge about experimental and simulation methods. To further elaborate the importance of environmentally safe chemical practice, the concept of green chemistry has also been covered. Specialized chapters have been included in the book about persistent organic pollutants, heavy metal and plastic pollutants, the effect of environmental xenoesterogens on human health and the potential of natural products to combat ecotoxicity. Key Features: 1. 10 topics which blend environmental chemistry and medicinal chemistry 2. Contributions from more than 30 experts 3. Includes introductory topics on environmental pollutants, investigative techniques in drug design and environmental risk assessment and green chemistry 4. Includes specialized topics on persistent pollutants, ecotoxicity remediation and xenoestrogens 5. Bibliographic references This reference is an essential source of information for readers and scholars involved in environmental chemistry, pollution management and pharmaceutical chemistry courses at graduate and undergraduate levels. Professionals and students involved in occupational medicine will also benefit from the wide range of topics covered.

Author : Carlos A. M. Afonso,Nuno R. Candeias,Dulce Pereira Simão,Alexandre F. Trindade,Jaime A. S. Coelho,Bin Tan,Robert Franzén
Publisher : Royal Society of Chemistry
Page : 976 pages
File Size : 48,5 Mb
Release : 2016-12-16
Category : Science
ISBN : 9781849739634

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Comprehensive Organic Chemistry Experiments for the Laboratory Classroom by Carlos A. M. Afonso,Nuno R. Candeias,Dulce Pereira Simão,Alexandre F. Trindade,Jaime A. S. Coelho,Bin Tan,Robert Franzén Pdf

This expansive and practical textbook contains organic chemistry experiments for teaching in the laboratory at the undergraduate level covering a range of functional group transformations and key organic reactions.The editorial team have collected contributions from around the world and standardized them for publication. Each experiment will explore a modern chemistry scenario, such as: sustainable chemistry; application in the pharmaceutical industry; catalysis and material sciences, to name a few. All the experiments will be complemented with a set of questions to challenge the students and a section for the instructors, concerning the results obtained and advice on getting the best outcome from the experiment. A section covering practical aspects with tips and advice for the instructors, together with the results obtained in the laboratory by students, has been compiled for each experiment. Targeted at professors and lecturers in chemistry, this useful text will provide up to date experiments putting the science into context for the students.

Author : H. Dupont Durst,George W. Gokel
Publisher : McGraw-Hill Science, Engineering & Mathematics
Page : 776 pages
File Size : 54,6 Mb
Release : 1987
Category : Science
ISBN : UOM:39015011621326

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Experimental Organic Chemistry by H. Dupont Durst,George W. Gokel Pdf

Author : Camille Georges Wermuth
Publisher : Elsevier
Page : 736 pages
File Size : 53,8 Mb
Release : 2003-06-11
Category : Science
ISBN : 9780080497778

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The Practice of Medicinal Chemistry by Camille Georges Wermuth Pdf

The Practice of Medicinal Chemistry, 2E, is a single-volume source on the practical aspects of medicinal chemistry. The successful first edition was nicknamed "The Bible" by medicinal chemists, and the second edition has been updated, expanded and refocused to reflect developments over the last decade. Emphasis is put on how medicinal chemists conduct their search for and design of new drug entities. In contrast to competing books, it focuses on the chemistry rather than pharmacological concepts or descriptions of the various therapeutic classes of drugs. Most medicinal chemists working in the pharmaceutical industry are organic synthetic chemists who must acquire a strong knowledge of medicinal chemistry as they enter the industry. This book aims to be their practical handbook - a complete guide to the drug discovery process. * The only book available dealing with the practical aspects of medicinal chemistry * Serves as a complete guide to the drug discovery process, from conception of the molecules to drug production * Updated chapters devoted to the discovery of new lead compounds, including combinatorial chemistry

Author : Jie Jack Li
Publisher : John Wiley & Sons
Page : 416 pages
File Size : 42,6 Mb
Release : 2020-06-29
Category : Medical
ISBN : 9781119607304

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Medicinal Chemistry for Practitioners by Jie Jack Li Pdf

Presenting both a panoramic introduction to the essential disciplines of drug discovery for novice medicinal chemists as well as a useful reference for veteran drug hunters, this book summarizes the state-of-the-art of medicinal chemistry. It covers key drug targets including enzymes, receptors, and ion channels, and hit and lead discovery. The book hen surveys a drug's pharmacokinetics and toxicity, with a solid chapter covering fundamental bioisosteres as a guide to structure-activity relationship investigations.

Author : B. R. Prashantha Kumar,T Durai Ananda Kumar,Swathi N
Publisher : Unknown
Page : 250 pages
File Size : 45,6 Mb
Release : 2021-09
Category : Electronic
ISBN : 938997495X

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Microwave Assisted Chemistry Experiments by B. R. Prashantha Kumar,T Durai Ananda Kumar,Swathi N Pdf

Author : K. S. Jain,T. S. Chitre
Publisher : Career Publishing (CA)
Page : 0 pages
File Size : 55,5 Mb
Release : 2007-10
Category : Medical
ISBN : 818873960X

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Experimental Pharmaceutical Organic Chemistry by K. S. Jain,T. S. Chitre Pdf

Topics 1. Safety In Laboratoy 2. Treatment Procedures For Various Kinds Of Injuries 3. Laboratory Techniques 4. Qualitative Organic Anylysis A. Preliminary Examination/Preliminary Test B. Detection Of Elements/Elemental Analysis C. Detection Of Functional Group D. Derivative Preparation E. Deterincation Of Binary Mixture F. Separation Of Functional Groups 5. Estimation Of Functional Groups 6. Analysis Of Oil 7. Organic Synthesis 8. Viva Voce Question Answers 9. Common Laboratory Reagents

Author : Daniel R. Palleros
Publisher : John Wiley & Sons
Page : 870 pages
File Size : 42,7 Mb
Release : 2000-02-04
Category : Science
ISBN : 9780471282501

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Experimental Organic Chemistry by Daniel R. Palleros Pdf

This cutting-edge lab manual takes a multiscale approach, presenting both micro, semi-micro, and macroscale techniques. The manual is easy to navigate with all relevant techniques found as they are needed. Cutting-edge subjects such as HPLC, bioorganic chemistry, multistep synthesis, and more are presented in a clear and engaging fashion.

Author : John Leonard,Barry Lygo,Garry Procter
Publisher : CRC Press
Page : 328 pages
File Size : 41,8 Mb
Release : 1994-06-02
Category : Science
ISBN : 0748740716

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Advanced Practical Organic Chemistry, Second Edition by John Leonard,Barry Lygo,Garry Procter Pdf

The first edition of this book achieved considerable success due to its ease of use and practical approach, and to the clear writing style of the authors. The preparation of organic compounds is still central to many disciplines, from the most applied to the highly academic and, more tan ever is not limited to chemists. With an emphasis on the most up-to-date techniques commonly used in organic syntheses, this book draws on the extensive experience of the authors and their association with some of the world's mleading laboratories of synthetic organic chemistry. In this new edition, all the figures have been re-drawn to bring them up to the highest possible standard, and the text has been revised to bring it up to date. Written primarily for postgraduate, advanced undergraduate and industrial organic chemists, particularly those involved in pharmaceutical, agrochemical and other areas of fine chemical research, the book is also a source of reference for biochemists, biologists, genetic engineers, material scientists and polymer researchers.