Exploring Protein Structure Principles And Practice

Author : Tim Skern
Publisher : Springer
Page : 255 pages
File Size : 46,7 Mb
Release : 2018-07-04
Category : Science
ISBN : 9783319768588

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Exploring Protein Structure: Principles and Practice by Tim Skern Pdf

This textbook introduces the basics of protein structure and logically explains how to use online software to explore the information in protein structure databases. Readers will find easily understandable, step-by step exercises and video-trainings to support them in grasping the fundamental concepts. After reading this book, readers will have the skills required to independently explore and analyze macromolecular structures, will be versed in extracting information from protein databases and will be able to visualize protein structures using specialized software and on-line algorithms. This book is written for advanced undergraduates and PhD students wishing to use information from structural biology in their assignments and research and will be a valuable source of information for all those interested in applied and theoretical aspects of structural biology.

Author : G.E. Schulz,R.H. Schirmer
Publisher : Springer Science & Business Media
Page : 328 pages
File Size : 54,5 Mb
Release : 2013-12-01
Category : Science
ISBN : 9781461261377

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Principles of Protein Structure by G.E. Schulz,R.H. Schirmer Pdf

New textbooks at all levels of chemistry appear with great regularity. Some fields like basic biochemistry, organic reaction mechanisms, and chemical thermodynamics are well represented by many excellent texts, and new or revised editions are published sufficiently often to keep up with progress in research. However, some areas of chemistry, especially many of those taught at the graduate level, suffer from a real lack of up-to-date textbooks. The most serious needs occur in fields that are rapidly changing. Textbooks in these subjects usually have to be written by scientists actually involved in the research which is advancing the field. It is not often easy to persuade such individuals to set time aside to help spread the knowledge they have accumulated. Our goal, in this series, is to pinpoint areas of chemistry where recent progress has outpaced what is covered in any available textbooks, and then seek out and persuade experts in these fields to produce relatively concise but instructive introductions to their fields. These should serve the needs of one semester or one quarter graduate courses in chemistry and biochemistry. In some cases the availability of texts in active research areas should help stimulate the creation of new courses.

Author : Jeffrey L. Cleland,Charles S. Craik
Publisher : Wiley-Liss
Page : 558 pages
File Size : 44,8 Mb
Release : 1996-02-07
Category : Science
ISBN : UOM:39015037309690

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Protein Engineering by Jeffrey L. Cleland,Charles S. Craik Pdf

PROTEIN ENGINEERING Principles and Practice Edited by JEFFREY L. CLELAND CHARLES S. CRAIK Proteins are involved in every aspect of life-structure, motion, catalysis, recognition and regulation. Protein Engineering: Principles and Practice provides a basic framework for understanding both proteins and protein engineering. This comprehensive book covers general, yet essential knowledge required for successful protein engineering, including everything from the fundamentals to modifying existing proteins and developing new proteins. The book begins by introducing the main concepts of protein engineering, including: understanding protein conformation, comprehending the relationship between protein composition and structure, and potential methods for predicting a protein's conformation. Other major subjects addressed are: * Using different host cell expression systems to produce specific proteins * Protein folding * Structure and function of proteins in relation to drug design * Construction of synthetic metal binding sites in proteins * Manufacture of tissue plasminogen activator * Generation of therapeutic antibodies This broad range of topics provides a solid foundation in protein engineering and supplies readers with knowledge essential to the design and production of proteins. Of primary interest to protein scientists-both students and researchers, in academia as well as industry-Protein Engineering is also extremely useful to chemical engineers, protein chemists, biochemists, and pharmaceutical chemists.

Author : Georg E. Schulz,R. Heiner Schirmer
Publisher : Unknown
Page : 314 pages
File Size : 46,5 Mb
Release : 1988
Category : Electronic
ISBN : OCLC:799586471

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Principles of Protein Structure by Georg E. Schulz,R. Heiner Schirmer Pdf

Author : G.D. Fasman
Publisher : Springer Science & Business Media
Page : 796 pages
File Size : 52,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461315711

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Prediction of Protein Structure and the Principles of Protein Conformation by G.D. Fasman Pdf

The prediction of the conformation of proteins has developed from an intellectual exercise into a serious practical endeavor that has great promise to yield new stable enzymes, products of pharmacological significance, and catalysts of great potential. With the application of predic tion gaining momentum in various fields, such as enzymology and immunology, it was deemed time that a volume be published to make available a thorough evaluation of present methods, for researchers in this field to expound fully the virtues of various algorithms, to open the field to a wider audience, and to offer the scientific public an opportunity to examine carefully its successes and failures. In this manner the practitioners of the art could better evaluate the tools and the output so that their expectations and applications could be more realistic. The editor has assembled chapters by many of the main contributors to this area and simultaneously placed their programs at three national resources so that they are readily available to those who wish to apply them to their personal interests. These algorithms, written by their originators, when utilized on pes or larger computers, can instantaneously take a primary amino acid sequence and produce a two-or three-dimensional artistic image that gives satisfaction to one's esthetic sensibilities and food for thought concerning the structure and function of proteins. It is in this spirit that this volume was envisaged.

Author : Pablo Carbonell
Publisher : Springer Nature
Page : 168 pages
File Size : 54,6 Mb
Release : 2019-11-05
Category : Medical
ISBN : 9783030298654

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Metabolic Pathway Design by Pablo Carbonell Pdf

This textbook presents solid tools for in silico engineering biology, offering students a step-by-step guide to mastering the smart design of metabolic pathways. The first part explains the Design-Build-Test-Learn-cycle engineering approach to biology, discussing the basic tools to model biological and chemistry-based systems. Using these basic tools, the second part focuses on various computational protocols for metabolic pathway design, from enzyme selection to pathway discovery and enumeration. In the context of industrial biotechnology, the final part helps readers understand the challenges of scaling up and optimisation. By working with the free programming language Scientific Python, this book provides easily accessible tools for studying and learning the principles of modern in silico metabolic pathway design. Intended for advanced undergraduates and master’s students in biotechnology, biomedical engineering, bioinformatics and systems biology students, the introductory sections make it also useful for beginners wanting to learn the basics of scientific coding and find real-world, hands-on examples.

Author : Michela Milano
Publisher : Springer
Page : 1015 pages
File Size : 41,9 Mb
Release : 2012-10-03
Category : Mathematics
ISBN : 9783642335587

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Principles and Practice of Constraint Programming - CP 2012 by Michela Milano Pdf

This book constitutes the thoroughly refereed post-conference proceedings of the 18th International Conference on Principles and Practice of Constraint Programming (CP 2012), held in Québec, Canada, in October 2012. The 68 revised full papers were carefully selected from 186 submissions. Beside the technical program, the conference featured two special tracks. The former was the traditional application track, which focused on industrial and academic uses of constraint technology and its comparison and integration with other optimization techniques (MIP, local search, SAT, etc.) The second track, featured for the first time in 2012, concentrated on multidisciplinary papers: cross-cutting methodology and challenging applications collecting papers that link CP technology with other techniques like machine learning, data mining, game theory, simulation, knowledge compilation, visualization, control theory, and robotics. In addition, the track focused on challenging application fields with a high social impact such as CP for life sciences, sustainability, energy efficiency, web, social sciences, finance, and verification.

Author : Mohammed Zaki,Chris Bystroff
Publisher : Springer Science & Business Media
Page : 338 pages
File Size : 50,5 Mb
Release : 2007-09-12
Category : Science
ISBN : 9781588297525

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Protein Structure Prediction by Mohammed Zaki,Chris Bystroff Pdf

This book covers elements of both the data-driven comparative modeling approach to structure prediction and also recent attempts to simulate folding using explicit or simplified models. Despite the unsolved mystery of how a protein folds, advances are being made in predicting the interactions of proteins with other molecules. Also rapidly advancing are the methods for solving the inverse folding problem, the problem of finding a sequence to fit a structure. This book focuses on the various computational methods for prediction, their successes and their limitations, from the perspective of their most well known practitioners.

Author : Timothy Skern
Publisher : UTB GmbH
Page : 218 pages
File Size : 46,8 Mb
Release : 2019-10-07
Category : Law
ISBN : 9783825250669

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Writing Scientific English by Timothy Skern Pdf

Das Verfassen wissenschaftlicher Arbeiten in englischer Sprache ist heute in vielen Studienrichtungen unerlässlich. Gleichzeitig stellt es für Studierende meist eine große Herausforderung dar. Dieses Buch leitet zur richtigen Arbeitsweise und zum korrekten Sprachgebrauch an und schließt damit eine Lücke in der einschlägigen Literatur. Anhand zahlreicher Beispiele werden sowohl gelungene Texte analysiert als auch typische Fehler deutschsprachiger Studierender korrigiert. Success in science depends nowadays on effective communication in English. This workbook is specifically designed to give under- and post-graduates confidence in writing scientific English. Examples and exercises show how to avoid common errors and how to rephrase and improve scientific texts. The generation of a model manuscript enables the reader to recognise how scientific English is constructed and how to follow the conventions of scientific writing. Guidelines for structuring written work and vocabulary lists will encourage young scientists to develop a concise and mature style. The workbook is accessible to students of many fields, including those of the natural and technical sciences, medicine, psychology and economics.

Author : Ivet Bahar,Robert L. Jernigan,Ken A. Dill
Publisher : Garland Science
Page : 336 pages
File Size : 50,7 Mb
Release : 2017-02-14
Category : Science
ISBN : 9781351815017

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Protein Actions: Principles and Modeling by Ivet Bahar,Robert L. Jernigan,Ken A. Dill Pdf

Protein Actions: Principles and Modeling is aimed at graduates, advanced undergraduates, and any professional who seeks an introduction to the biological, chemical, and physical properties of proteins. Broadly accessible to biophysicists and biochemists, it will be particularly useful to student and professional structural biologists and molecular biophysicists, bioinformaticians and computational biologists, biological chemists (particularly drug designers) and molecular bioengineers. The book begins by introducing the basic principles of protein structure and function. Some readers will be familiar with aspects of this, but the authors build up a more quantitative approach than their competitors. Emphasizing concepts and theory rather than experimental techniques, the book shows how proteins can be analyzed using the disciplines of elementary statistical mechanics, energetics, and kinetics. These chapters illuminate how proteins attain biologically active states and the properties of those states. The book ends with a synopsis the roles of computational biology and bioinformatics in protein science.

Author : Leonard J. Banaszak
Publisher : Elsevier
Page : 168 pages
File Size : 54,8 Mb
Release : 2000-02-08
Category : Science
ISBN : 0080521843

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Foundations of Structural Biology by Leonard J. Banaszak Pdf

Imagine trying to understand an engine without visualizing its moving parts. Biological processes involve far more complex chemical reactions and components than any engine. Furthermore, the parts work together to do many more functions than an engine which sole task is to turn a shaft. Understanding the implications of the three-dimensional coordinates for a molecule with several thousand atoms requires an understanding of, and practice with, 3D imaging. For many biologists, this means acquiring a whole new set of skills. Foundations of Structural Biology is aimed at helping the reader develop visualization skills for protein or DNA segments, while also describing the fundamental principles underlying the organization and interaction between these complex molecules. Key Features * Explains how to use coordinate databases and atomic coordinates of biological macromolecules * Teaches the skills of stereoviewing * Contains computer-generated stereographics * Describes the principles of symmetry and handedness in proteins and DNA * Introduces metal and lipid binding proteins and DNA-protein interactions * Explains the principles involved in understanding secondary and quaternary structure * Includes coverage of protein-metal, protein-nucleic acid, and protein-lipid interactions

Author : Carl-Ivar Brändén,John Tooze
Publisher : Taylor & Francis
Page : 410 pages
File Size : 40,7 Mb
Release : 1999
Category : Medical
ISBN : 9780815323051

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Introduction to Protein Structure by Carl-Ivar Brändén,John Tooze Pdf

This new edition gives an up-to-date account of the principles of protein structure, with examples of key proteins in their biological context, illustrated in colour to illuminate the structural principles described in the text.

Author : Gregory A. Petsko,Dagmar Ringe
Publisher : New Science Press
Page : 220 pages
File Size : 47,8 Mb
Release : 2004
Category : Proteins
ISBN : 9780878936632

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Protein Structure and Function by Gregory A. Petsko,Dagmar Ringe Pdf

Each title in the 'Primers in Biology' series is constructed on a modular principle that is intended to make them easy to teach from, to learn from, and to use for reference.

Author : Carl Ivar Branden,John Tooze
Publisher : Garland Science
Page : 424 pages
File Size : 41,7 Mb
Release : 2012-03-26
Category : Science
ISBN : 9781136969898

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Introduction to Protein Structure by Carl Ivar Branden,John Tooze Pdf

The VitalBook e-book of Introduction to Protein Structure, Second Edition is inly available in the US and Canada at the present time. To purchase or rent please visit http://store.vitalsource.com/show/9780815323051Introduction to Protein Structure provides an account of the principles of protein structure, with examples of key proteins in their bio

Author : Gail Wiscarz Stuart
Publisher : Elsevier Health Sciences
Page : 832 pages
File Size : 49,7 Mb
Release : 2014-04-14
Category : Medical
ISBN : 9780323294126

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Principles and Practice of Psychiatric Nursing by Gail Wiscarz Stuart Pdf

Using the latest clinical research and diagnoses, Principles and Practice of Psychiatric Nursing, 10th Edition provides a holistic, biopsychosocial approach to psychiatric nursing care. It follows the popular Stuart stress-adaptation framework and includes comprehensive coverage to simplify important nursing and medical concepts, promote quality and safety in care, and address psychobiology and psychopharmacology topics integral to today’s psychiatry. New to this edition is a chapter on psychiatric care of military personnel, plus the latest on health care reform, prescription abuse, and obesity issues. Written by psychiatric nursing expert Gail W. Stuart, this market-leading text makes it easy to apply classroom theory to clinical practice. An easy-to-follow writing style makes it easy to understand both simple and complex topics. A well-rounded, collaborative approach provides coverage of all major psychiatric disorders from nursing and medical perspectives. The Stuart Stress Adaptation Model of health and wellness provides a consistent nursing-oriented framework, with clear explanations of biological, psychological, sociocultural, environmental, and legal-ethical components. An evidence-based practice approach bridges the gap between clinical research and everyday practice. Learning from a Clinical Case boxes begin disorders chapters with thought-provoking questions and end chapters with answers and feedback. Summarizing the Evidence boxes in the disorders chapters examine the research and findings that support psychiatric nursing care. A family focus and discussions of outpatient care reflect current trends in psychiatric nursing. A Patient Speaks and A Family Speaks boxes present short vignettes with the patient’s and family’s perspectives of the caregiving process. Competent Caring: A Clinical Exemplar of a Psychiatric Nurse boxes feature the experiences and personal insights of practicing psychiatric nurses. Medical and Nursing Diagnoses boxes and Detailed Diagnoses tables emphasize the interdisciplinary approach to patient care by presenting NANDA diagnoses relevant to specific disorders and describing the essential features of the related DSM-IV-TR diagnoses. Nursing Treatment Plan Summary tables present care plans including patient goals with nursing interventions and rationales. Patient Education Plan and Family Education Plan tables include key information that you need to share with the patient and his or her family to facilitate shorter hospital stays and more outpatient care. Therapeutic Dialogue boxes offer examples of nurse-patient interactions. Clinical examples include selected nursing diagnoses. Focus Points provide a comprehensive, point-by-point review of the important information in each chapter.