Extinction Reversed

Author : J.S. Morin
Publisher : Magical Scrivener Press
Page : 421 pages
File Size : 44,9 Mb
Release : 2017-04-21
Category : Fiction
ISBN : 9781942642237

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Extinction Reversed by J.S. Morin Pdf

These days, even the humans are built by robots. Charlie7 is the progenitor of a mechanical race he built from the ashes of a dead world—Earth. He is a robot of leisure and idle political meddling—a retirement well-earned. Or he was, until a human girl named Eve was dropped in his lap. Geneticists have restored Earth’s biome and begun repopulation. But primate cloning is in its infancy; human cloning is banned. Far from a failed genetics experiment, Eve is brilliant, curious, and heartbreakingly naïve about her species’ history. But Eve’s creator wants her back and has a gruesome fate planned for her. There is only one robot qualified to protect her. For the first time in a thousand years, Charlie7 has a human race to protect. A.I. didn’t destroy humanity. It didn’t save us, either. The robots we built in our final days preserved human minds. They survived the end of life on Earth and embarked on the greatest single project in all recorded history. They rebuilt. The result of 1,000 years of genetic engineering, terraforming, and painstaking toxic cleanup has resulted in the ultimate achievement of the Post-Invasion Age: a healthy human. Her name is Eve14. Don’t ask about the 13 Eves before her. Or do, because that’s the reason why she’s in danger, and why one brave robot puts his millennium-long life on the line to save her. Welcome back to the Golden Age of science fiction, when scientists had planet-sized dreams and robots were robots. Grab your copy while there’s still an Earth left to read it on.

Author : Israel Liberzon,Shane Alan Perrine
Publisher : Frontiers Media SA
Page : 194 pages
File Size : 51,9 Mb
Release : 2019-12-17
Category : Electronic
ISBN : 9782889632510

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Pre-Clinical Models of PTSD by Israel Liberzon,Shane Alan Perrine Pdf

Author : Denise Manahan-Vaughan,Onur Gunturkun,Oliver T. Wolf
Publisher : Frontiers Media SA
Page : 279 pages
File Size : 50,9 Mb
Release : 2016-08-08
Category : Extinction (Psychology)
ISBN : 9782889199082

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Extinction Learning from a Mechanistic and Systems Perspective by Denise Manahan-Vaughan,Onur Gunturkun,Oliver T. Wolf Pdf

Throughout their lifetime, animals learn to associate stimuli with their consequences. Following memory acquisition and consolidation, circumstances may arise that necessitate that initially learned behaviour is no longer relevant. The ensuing process is called extinction learning and involves a novel and complex learning procedure that involves a large number of neural entities. While the neural fundaments of the initial acquisition are well studied, our understanding of the behavioural and neural basis of extinction is still limited and derives mostly from rodent data acquired through fear conditioning paradigms. Fear conditioning and extinction in rodents is a spectacularly successful paradigm within behavioral neuroscience. However, in recent years, new approaches have been emerging that examine the mechanisms of extinction learning in different setting that also involve appetitive models, a broader comparative perspective, a focus on other brain systems, an examination of hormonal factors, and conditioning of immune responses. Only a broader analysis of the neural fundaments of extinction learning will finally uncover shared and distinct mechanisms that underlie extinction learning in different functional systems. The papers compiled in this Research Topic offer new and valuable insights into the mechanisms and functional implementation of extinction learning at its different levels of complexity, and form the basis for new concepts and research ideas in this field.

Author : Christa McIntyre,Jonathan Eric Ploski
Publisher : Frontiers Media SA
Page : 137 pages
File Size : 50,6 Mb
Release : 2015-08-21
Category : Electronic book
ISBN : 9782889196067

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Emotional Modulation of the Synapse by Christa McIntyre,Jonathan Eric Ploski Pdf

Highly emotional events tend to be well remembered. The adaptive value in this is clear – those events that have a bearing on survival should be stored for future use as long-term memories whereas memories of inconsequential events would not as likely contribute to future survival. Enduring changes in the structure and function of synapses, neural circuitry, and ultimately behavior, can be modulated by highly aversive or rewarding experiences. In the last decade, the convergence of cellular, molecular, and systems neuroscience has produced new insights into the biological mechanisms that determine whether a memory will be stored for the long-term or lost forever. This Research Topic brings together leading experts, who work at multiple levels of analysis, to reveal recent discoveries and concepts regarding the synaptic mechanisms of consolidation and extinction of emotionally arousing memories.

Author : R. M. Gilbert,J. R. Millenson
Publisher : Academic Press
Page : 303 pages
File Size : 55,7 Mb
Release : 2014-05-10
Category : Psychology
ISBN : 9781483266244

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Reinforcement by R. M. Gilbert,J. R. Millenson Pdf

Reinforcement: Behavioral Analyses covers the proceedings of the 1970 Symposium on Schedule-induced and Schedule-Dependent Phenomena, held in Toronto, Ontario, Canada. This symposium highlights theoretically inclined papers on reinforcement processes. This text contains 10 chapters and begins with a description of how behavior is induced by various environmental events, especially reinforcing events, as well as the relationship between control by inducing stimuli and reinforceability. The subsequent chapters deal with reinforcement phenomena in terms of preference relations and the conditioned emotional responses in terms of opposing motivational processes. These topics are followed by reviews of schedule-dependent effects of preaversive stimuli and the maintenance of behavior by apparent reinforcers that might be expected to punish, as well as the identification of critical variable that underlie the phenomenon. Other chapters examine the interactions between operant and responded conditioning processes. The final chapters outline the experiments on behavior stream whose hallmark is reinforcement if the absence of specified behavior. These chapters emphasize the analogy between the evolution of species and the modification of behavior. This book will be of value to behaviorists and psychologists.

Author : Christopher Belshaw
Publisher : Routledge
Page : 304 pages
File Size : 49,9 Mb
Release : 2020-10-28
Category : Philosophy
ISBN : 9781000199932

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The Value and Meaning of Life by Christopher Belshaw Pdf

In this book Christopher Belshaw draws on earlier work concerning death, identity, animals, immortality, and extinction, and builds a large-scale argument dealing with questions of both value and meaning. Rejecting suggestions that life is sacred or intrinsically valuable, he argues instead that its value varies, and varies considerably, both within and between different kinds of things. So in some cases we might have reason to improve or save a life, while in others that reason will be lacking. What about starting lives? The book’s central section takes this as its focus, and asks whether we ever have reason to start lives, just for the sake of the one whose life it is. Not only is it denied that there is any such reason, but some sympathy is afforded to the anti-natalist contention that there is always reason against. The final chapters deal with meaning. There is support here for the sober and familiar view that meaning derives from an enthusiasm for, and some success with, the pursuit of worthwhile projects. Now suppose we are immortal. Or suppose, in contrast, that we face imminent extinction. Would either of these threaten meaning? The claim is made that the force of such threats is often exaggerated. The Value and Meaning of Life is essential reading for students and researchers in philosophy, ethics, and religion, and will be of interest to all those concerned with how to live, and how to think about the lives of others.

Author : Anonim
Publisher : Unknown
Page : 356 pages
File Size : 54,7 Mb
Release : 1889
Category : Mineralogy
ISBN : STANFORD:36105006925031

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Mineralogical Magazine by Anonim Pdf

Author : Anonim
Publisher : Unknown
Page : 364 pages
File Size : 44,9 Mb
Release : 1889
Category : Mineralogy
ISBN : IND:30000145713107

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The Mineralogical Magazine and Journal of the Mineralogical Society by Anonim Pdf

Author : Barbara McEwen
Publisher : Academic Press
Page : 791 pages
File Size : 55,5 Mb
Release : 2004-09-15
Category : Science
ISBN : 9780080524511

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Roles of Vasopressin and Oxytocin in Memory Processing by Barbara McEwen Pdf

The Roles of Vasopressin and Oxytocin in Memory Processing reviews research progress in a subfield of Behavioral Pharmacology concerned with vasopressin’s (VP’s) and oxytocin (OT’s) roles in memory processing (MP). As hormones, VP is well-known for its pressor and antidiuretic action, and OT for its contribution to parturition and nursing. As neurotransmitters, they participate in a wide variety of self- and species-preserving functions expressed at psychological, physiological and behavioral levels. Advances in Pharmacology is available online on ScienceDirect — full-text online of volumes 48 onwards. Elsevier book series on ScienceDirect gives multiple users throughout an institution simultaneous online access to an important compliment to primary research. Digital delivery ensures users reliable, 24-hour access to the latest peer-reviewed content. The Elsevier book series are compiled and written by the most highly regarded authors in their fields and are selected from across the globe using Elsevier’s extensive researcher network. For more information about the Elsevier Book Series on ScienceDirect Program, please visit:http://www.info.sciencedirect.com/bookseries/ * Comprehensive coverage of both alternative theories and relevant research* Several key chapters reviewed by researchers whose studies and theories formed the subject matter of these chapters* Basic laboratory research focus with potential application for understanding and treating human memory disorders

Author : Alia Benali,Ken-Ichiro Tsutsui,Friederike Pfeiffer,Masaki Sekino
Publisher : Frontiers Media SA
Page : 294 pages
File Size : 53,8 Mb
Release : 2022-12-08
Category : Science
ISBN : 9782832507575

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Brain stimulation: from basic research to clinical use by Alia Benali,Ken-Ichiro Tsutsui,Friederike Pfeiffer,Masaki Sekino Pdf

Author : Patrizia Campolongo,Liana Fattore
Publisher : Springer
Page : 471 pages
File Size : 44,9 Mb
Release : 2015-05-18
Category : Medical
ISBN : 9781493922949

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Cannabinoid Modulation of Emotion, Memory, and Motivation by Patrizia Campolongo,Liana Fattore Pdf

The endocannabinoid system consists of cannabinoid receptors, their endogenous lipid ligands (endocannabinoids) and the enzymatic machinery for their synthesis and degradation. In the brain, endocannabinoids regulate ion channel activity and neurotransmitter release and thereby contribute to various aspects of brain function, including memory, reward and emotions. Their ability to modulate synaptic efficacy has a wide range of functional consequences and provides unique therapeutic possibilities. Unprecedented advances have been made in the understanding of the role of endocannabinoids in the regulation of the emotional brain over the past few years. However, a comprehensive book encompassing all these aspects is still lacking. The book will provide an overview of the role played by the endocannabinoid system in the regulation of emotional processes with particular emphasis on the modulation of memory and reward for emotionally arousing events and for the regulation of motivational aspects in cannabis use.

Author : Nicholas W Gilpin,Remi Martin-Fardon
Publisher : Frontiers Media SA
Page : 185 pages
File Size : 52,5 Mb
Release : 2015-03-26
Category : Brain
ISBN : 9782889194575

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Brain Reward & Stress Systems in Addiction by Nicholas W Gilpin,Remi Martin-Fardon Pdf

Addiction to drugs and alcohol is a dynamic and multi-faceted disease process in humans, with devastating health and financial consequences for the individual and society-at-large. In humans, drug and alcohol use disorders (i.e., abuse and dependence) are defined by clusters of behavioral symptoms that can be modeled to various degrees in animals. Hallmark behavioral symptoms associated with drug and alcohol dependence are compulsive drug use, loss of control during episodes of drug use, the emergence of a negative emotional state in the absence of the drug, and chronic relapse vulnerability during drug abstinence. The transition to drug dependence is defined by neuroadaptations in brain circuits that, in the absence of drugs, mediate a variety of critical behavioral and physiological processes including natural reward, positive and negative emotional states, nociception, and feeding. Chronic drug exposure during the transition to dependence spurs (1) within-systems changes in neural circuits that contribute to the acute rewarding effects of the drug and (2) recruitment of brain stress systems (neuroendocrine and extra-hypothalamic). There are substantial genetic contributions to the propensity to use and abuse drugs, and drug abuse is highly co-morbid with various other psychiatric conditions (e.g., anxiety disorders, major depressive disorder) that may precede or follow the development of drug use problems. Across drugs of abuse, there are overlapping and dissociable aspects of the behavioral and neural changes that define the transition to dependence. Even within a single drug, people abuse drugs for a variety of reasons. The picture is further complicated by the fact that humans often abuse more than one drug concurrently. Even in the face of these challenges, pre-clinical and clinical research is making exponential gains into understanding the neurobiology of drug addiction. With the advent of new technologies and their combination with traditional approaches, the field is able to ask and answer addiction-related research questions in increasingly sophisticated ways. Here, we hope to assemble a collection of articles that provide an up-to-the-moment snapshot of the prevailing empirical, theoretical and technical directions in the addiction research field. We encourage submissions from all investigators working to understand the neurobiology of addiction, especially as it pertains to reward and stress pathways in the brain.

Author : Wayne W. Fisher,Cathleen C. Piazza,Henry S. Roane
Publisher : Guilford Publications
Page : 642 pages
File Size : 51,7 Mb
Release : 2021-06-01
Category : Psychology
ISBN : 9781462544110

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Handbook of Applied Behavior Analysis by Wayne W. Fisher,Cathleen C. Piazza,Henry S. Roane Pdf

Widely regarded as the authoritative work on the principles and practice of applied behavior analysis (ABA), this indispensable volume is now in a revised and expanded second edition. Leading experts present evidence-based procedures for supporting positive behaviors and reducing problem behaviors with children and adults in diverse contexts. Chapters delve into applications in education, autism treatment, addictions, behavioral pediatrics, and other areas. Covering everything from behavioral assessment and measurement to the design and implementation of individualized interventions, the Handbook is a complete reference and training tool for ABA practitioners and students. New to This Edition *Incorporates key advances in research, theory, and clinical practice. *Chapters on additional applications: school consultation, pediatric feeding disorders, and telehealth services. *Chapters on quantitative analysis of behavior (matching and behavioral momentum theory) and behavioral economics. *Updated discussions of professional issues, ABA certification, and technology tools.

Author : Wayne W. Fisher,Cathleen C. Piazza,Henry S. Roane
Publisher : Guilford Publications
Page : 642 pages
File Size : 42,9 Mb
Release : 2021-07-14
Category : Psychology
ISBN : 9781462543755

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Handbook of Applied Behavior Analysis, Second Edition by Wayne W. Fisher,Cathleen C. Piazza,Henry S. Roane Pdf

Widely regarded as the authoritative work on the principles and practice of applied behavior analysis (ABA), this indispensable volume is now in a revised and expanded second edition. Leading experts present evidence-based procedures for supporting positive behaviors and reducing problem behaviors with children and adults in diverse contexts. Chapters delve into applications in education, autism treatment, addictions, behavioral pediatrics, and other areas. Covering everything from behavioral assessment and measurement to the design and implementation of individualized interventions, the Handbook is a complete reference and training tool for ABA practitioners and students. New to This Edition *Incorporates key advances in research, theory, and clinical practice. *Chapters on additional applications: school consultation, pediatric feeding disorders, and telehealth services. *Chapters on quantitative analysis of behavior (matching and behavioral momentum theory) and behavioral economics. *Updated discussions of professional issues, ABA certification, and technology tools.

Author : Anonim
Publisher : ScholarlyEditions
Page : 235 pages
File Size : 42,7 Mb
Release : 2012-01-09
Category : Medical
ISBN : 9781464967573

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Issues in Pharmaceuticals by Disease, Disorder, or Organ System: 2011 Edition by Anonim Pdf

Issues in Pharmaceuticals by Disease, Disorder, or Organ System: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Pharmaceuticals by Disease, Disorder, or Organ System. The editors have built Issues in Pharmaceuticals by Disease, Disorder, or Organ System: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Pharmaceuticals by Disease, Disorder, or Organ System in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Pharmaceuticals by Disease, Disorder, or Organ System: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.