Extrachromosomal Dna

Author : Donald Cummings
Publisher : Elsevier
Page : 581 pages
File Size : 54,7 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323145350

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Extrachromosomal DNA by Donald Cummings Pdf

Extrachromosomal DNA contains the proceedings of the 1979 ICN-UCLA Symposia on Molecular and Cellular Biology held in Keystone, Colorado. Contributors focus on extrachromosomal DNA, paying particular attention to the biogenesis of yeast mitochondria. They discuss topics based on the premise that the diversity and complexity of primitive mitochondrial and perhaps chloroplast DNA structure and replication have more in common with many viral systems than with either prokaryotic or eukaryotic systems. This is especially striking in the case of so-called split genes. This book is organized into nine sections encompassing 34 chapters and begins with an overview of extranuclear genetics and the evolution and regulation of mitochondrial biogenesis. The following chapters explore the genetic capacity and structure of chloroplast DNA, viral replication and function, and viral nucleic acids. The possibility of isolating mutants in some intervening sequences and analyzing their effect in loci of known genetic function is demonstrated. The reader is also introduced to the analysis of intervening genes and its importance in yeast mitochondria, as well as the sequencing of a variety of genes of known function. This book also considers the organization, function, and expression of extrachromosomal DNA in yeast, along with the genetics and biogenesis of mitochondrial DNA from higher eukaryotes, and then concludes with a description of the biological and structural characteristics of kinetoplast and Podospora mitochondrial DNA. This book will be of interest to researchers involved in mitochondrial, chloroplast, plasmid, and viral DNA function and replication.

Author : Reed Wickner
Publisher : Springer Science & Business Media
Page : 550 pages
File Size : 52,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781468452518

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Extrachromosomal Elements in Lower Eukaryotes by Reed Wickner Pdf

Author : Herbert Pfister
Publisher : CRC Press
Page : 272 pages
File Size : 51,8 Mb
Release : 1990-04-05
Category : Medical
ISBN : 0849358604

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Papillomaviruses and Human Cancer by Herbert Pfister Pdf

This volume gives special reference to papillomaviruses in benign precursor lesions related to genital tumors, plus it provides a basis for a more reproducible evaluation of the pathology of papillomavirus-induced lesions. It deals with the molecular biology of papillomaviruses as it relates to our understanding of viral cell transformation and malignant conversion. Written in a comprehensive, easy-to-read format, this book covers points of medical interest such as diagnosis, therapy, and prospects for vaccination. This fascinating text provides current, state-of-the-art practices for immediate and future medical research. Virologists, microbiologists, and cancer researchers will find this work interesting and resourceful.

Author : Tzvi Tzfira,Vitaly Citovsky
Publisher : Springer Science & Business Media
Page : 250 pages
File Size : 53,6 Mb
Release : 2005-04-12
Category : Science
ISBN : 030648241X

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Nuclear Import and Export in Plants and Animals by Tzvi Tzfira,Vitaly Citovsky Pdf

Nuclear Import and Export in Plants and Animals provides insight into the remarkable mechanisms of nuclear import and export. This book covers a range of topics from the nuclear pore structure, to nuclear import and export of macromolecules in plant and animal cells. In addition, the book covers the special cases of nuclear import of Agrobacterium T-DNA during plant genetic transformation, nuclear import and export of animal viruses, and nuclear intake of foreign DNA. A chapter on research methods to study nuclear transport concludes the book.

Author : H. Akai,R.C. King
Publisher : Springer Science & Business Media
Page : 498 pages
File Size : 48,5 Mb
Release : 2013-11-09
Category : Science
ISBN : 9781461572664

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Insect Ultrastructure by H. Akai,R.C. King Pdf

Fourteen years have passed since the publication of David Spencer Smith's Insect Cells: Their Structure and Function. Here the results of a decade of electronmicroscopic studies on insect cells were summarized in an organized and integrated fashion for the first time, and the ultrastructural characteristics of different specialized cells and tissues were abundantly illustrated in the 117 plates this monograph contained. In the intervening period great progress has been made in the field of Insect Ultrastructure. Organelles not even mentioned in Smith's book, such as synaptonemal complexes, clathrin baskets, fusomes, and retinular junc tions, have been identified and functions proposed for them. There have also been many technical advances that have profoundly influenced the direction of subsequent research. A spectacular example would be the development by Miller and Beatty of the chromosomal spreading technique which allowed for the first time ultrastructural studies on segments of chromosomes containing genes in various stages of replication and transcription. Then there is the freeze-fracture procedure first described by Moor and his colleagues. This technique permitted an analysis of intercellular junctions that was impossible with the conventional sectioning methods. The results greatly clarified our understanding of the channels for ion movement and the permeability barriers between cells and also the membrane changes that occur during the embryonic differentiation and metamorphosis of various types of insect cells.

Author : Thomas C. Cheng
Publisher : Springer Science & Business Media
Page : 189 pages
File Size : 41,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461593881

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Pathogens of Invertebrates by Thomas C. Cheng Pdf

Invertebrate pathology, like medical and veterinary pathology, for many years has been spearheaded by practical applications al though in more recent times many investigators have elected to focus their attention on basic mechanisms and the elucidation of basic phenomena. Although Elie Metachnikoff and Louis Pasteur may be considered the forerunners of invertebrate pathology, in modern times the late Edward A. Steinhaus and the late Arthur M. Heimpel, among others, must be considered the principal disciples. Con sequently, in recent years several symposia have been organized in honor of the memory of Steinhaus and Heimpel. When the proceedings of these occasions were examined and reviewed, it was decided that these could naturally be considered chapters of a single volume of Comparative Pathobiology under the subtitle selected. We wish to note that the chapters devoted to various aspects of Bacillus thuringiensis were originally presented at the thirteenth annual meeting of the Society for Invertebrate Pathology held in Seattle, Washington, on July 26 - August 2, 1980, under the title of the "Edward A. Steinhaus Memorial Symposium". This includes the contribution by Dr. Robert M. Faust on the professional contributions of Dr. Arthur M. Heimpel. Art, as he was known to his friends, was a founding member of the Society and later served as its president. The circle of his professional associates was international.

Author : H.H. Hagedorn,J.G. Hildebrand,M.G. Kidwell,J.H. Law
Publisher : Springer Science & Business Media
Page : 400 pages
File Size : 41,9 Mb
Release : 2013-12-14
Category : Science
ISBN : 9781489936684

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Molecular Insect Science by H.H. Hagedorn,J.G. Hildebrand,M.G. Kidwell,J.H. Law Pdf

This volume contains the scientific papers and abstracts of posters presented at the International Symposium on Molecular Insect Science held in Tucson, Arizona, October 22-27, 1989. This meeting was organized by the Center for Insect Science at the University of Arizona in response to the growing need for a forum dedicated to the impact of modern biology on insect science. While scientific studies of a few insects, notably Drosophila melanogaster, have always had a central role in the development of biology, it is only recently that tools have become available to extend these studies to other insects, including those having economic and medical importance. The Tucson meeting was evidence of how far we have come in extending modern biological tools to the study of insects. It is also evident from the contents of this book that the study of insects is making an increasingly important contribution to the advancement of biology generally. Given the large impact of insects on human life, such a development has considerable importance for human welfare, and of the welfare of the ecosystem as a whole. It should be noted that several of the participants who presented posters were invited to prepare full length papers to ensure that the book covered the major areas of insect science. The financial support of the National Science Foundation and the Monsanto Corporation is gratefully acknowledged. Thanks are also due to Sharon Richards for her dedicated work on the manuscripts. Henry H.

Author : Danni Gilmore
Publisher : Scientific e-Resources
Page : 320 pages
File Size : 55,9 Mb
Release : 2019-04-19
Category : Electronic
ISBN : 9781839471742

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Biochemistry and Molecular Biology of Plants by Danni Gilmore Pdf

Membrane structures are spatial structures made out of tensioned membranes. The structural use of membranes can be divided into pneumatic structures, tensile membrane structures, and cable domes. In these three kinds of structure, membranes work together with cables, columns and other construction members to find a form. Peripheral membrane proteins are found on the outside and inside surfaces of membranes, attached either to integral proteins or to phospholipids. Unlike integral membrane proteins, peripheral membrane proteins do not stick into the hydrophobic core of the membrane, and they tend to be more loosely attached. Cells are the smallest units of life. They are a closed system, can self-replicate, and are the building blocks of our bodies. In order to understand how these tiny organisms work, we will look at a cell's internal structures. We will focus on eukaryotic cells, cells that contain a nucleus. Prokaryotic cells, cells that lack a nucleus, are structured differently. The cell membrane is an extremely pliable structure composed primarily of back-to-back phospholipids (a "e;bilayer"e;). Cholesterol is also present, which contributes to the fluidity of the membrane, and there are various proteins embedded within the membrane that have a variety of functions. Today, the DNA double helix is probably the most iconic of all biological molecules. It's inspired staircases, decorations, pedestrian bridges and more. A vesicular transport protein, or vesicular transporter, is a membrane protein that regulates or facilitates the movement of specific molecules across a vesicle's membrane. As a result, vesicular transporters govern the concentration of molecules within a vesicle. Plants require higher amounts of nitrogen as it is important in their structure and metabolism. Nearly, 80 per cent of the earth's atmosphere is composed of nitrogen, bathing the entire plant world, but unfortunately most plants cannot utilize it in its elementary form. The book is a meticulously organized and richly illustrated work, useful both for teaching and for reference. It is intended to serve plant biology and related disciplines, ranging from molecular biology and biotechnology to biochemistry, cell biology, physiology, and ecology. Researchers in the pharmaceutical, biotechnology, and agribusiness industries will find a wealth of information inside.

Author : Robert F. Ozols
Publisher : Springer Science & Business Media
Page : 314 pages
File Size : 45,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461538721

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Molecular and Clinical Advances in Anticancer Drug Resistance by Robert F. Ozols Pdf

The importance of drug resistance in cancer chemotherapy cannot be over stated. The 500,000 patients who die every year from cancer in the United States have, in most cases, been treated with chemotherapy. Many of these patients responded initially to chemotherapy, but death resulted from the development of drug-resistant tumors. In the first volume in the series. Drug Resistance in Chemotherapy the results of comprehensive laboratory studies aimed at understanding the mechanisms for resistance to individual agents and to the development of broad cross-resistance were described. In the past 2 years there has been substantial progress in understanding the molecular biology associated with these mechanisms of drug resistance. For the first time we are starting to understand which mechanisms are playing an im portant role in human tumors, and even more importantly, clinical trials have recently been initiated in an effort to reverse specific forms of drug resistance. The purpose of this volume is to describe the new advances, both at the molecular level and in the clinic regarding mechanisms of drug resistance and potential ways this resistance can be circumvented. This volume is focused upon mechanisms of resistance associated with two major classes of anticancer drugs: alkylating agents (including cisplatin) and the natural products (e. g. , adriamycin and vinblastine). The first section of the book describes new insights into the genetic mechanisms associated with drug resistance.

Author : Athena Aktipis
Publisher : Princeton University Press
Page : 256 pages
File Size : 40,5 Mb
Release : 2021-09-07
Category : Medical
ISBN : 9780691212197

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The Cheating Cell by Athena Aktipis Pdf

A fundamental and groundbreaking reassessment of how we view and manage cancer When we think of the forces driving cancer, we don’t necessarily think of evolution. But evolution and cancer are closely linked because the historical processes that created life also created cancer. The Cheating Cell delves into this extraordinary relationship, and shows that by understanding cancer’s evolutionary origins, researchers can come up with more effective, revolutionary treatments. Athena Aktipis goes back billions of years to explore when unicellular forms became multicellular organisms. Within these bodies of cooperating cells, cheating ones arose, overusing resources and replicating out of control, giving rise to cancer. Aktipis illustrates how evolution has paved the way for cancer’s ubiquity, and why it will exist as long as multicellular life does. Even so, she argues, this doesn’t mean we should give up on treating cancer—in fact, evolutionary approaches offer new and promising options for the disease’s prevention and treatments that aim at long-term management rather than simple eradication. Looking across species—from sponges and cacti to dogs and elephants—we are discovering new mechanisms of tumor suppression and the many ways that multicellular life-forms have evolved to keep cancer under control. By accepting that cancer is a part of our biological past, present, and future—and that we cannot win a war against evolution—treatments can become smarter, more strategic, and more humane. Unifying the latest research from biology, ecology, medicine, and social science, The Cheating Cell challenges us to rethink cancer’s fundamental nature and our relationship to it.

Author : Jian Ma
Publisher : Springer Nature
Page : 508 pages
File Size : 52,5 Mb
Release : 2024-07-03
Category : Electronic
ISBN : 9781071639894

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Research in Computational Molecular Biology by Jian Ma Pdf

Author : Ira Ida Skvortsova,Elvira V. Grigorieva,Simona Kranjc Brezar,Yue Zhao
Publisher : Frontiers Media SA
Page : 361 pages
File Size : 47,5 Mb
Release : 2023-03-24
Category : Science
ISBN : 9782832517949

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Cancer cell reprogramming: Impact on carcinogenesis and cancer progression by Ira Ida Skvortsova,Elvira V. Grigorieva,Simona Kranjc Brezar,Yue Zhao Pdf

Author : R Whitcomb
Publisher : Elsevier
Page : 681 pages
File Size : 46,5 Mb
Release : 2012-12-02
Category : Nature
ISBN : 9780323143554

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The Mycoplasmas V5 by R Whitcomb Pdf

The Mycoplasmas,Volume V: Spiroplasmas, Acholeplasmas,and Mycoplasmas of Plants and Arthropods focuses on existing knowledge and recent development in research on spiroplasmas, acholeplasmas, and other mollicutes of plants and arthropods. Organized into 11 chapters, this volume discusses the nutrition, cultivation, ecology, and molecular and cellular biology of spiroplasmas. Because the occurrence of other mollicutes (mycoplasma and acholeplasma) in plant and arthropod environments is not extensively discussed in other volumes, this volume shows the rapid progress in describing the new mollicutes from arthropods and plant surface that they contaminate. Molecular studies of mollicute phylogeny and plant infections incited by the so-called mycoplasma-like organisms are also presented. This book will provide a comprehensive reference source for all mycoplasmologists and a relevant and exhaustive summary of recent advances in the study of spiroplasmas, acholeplasmas, and mycoplasmas in plant and arthropod hosts for microbiologists, cellular and molecular biologists, plant pathologists, and entomologists.

Author : Dr. Anusha G,Dr. Maheshwary D,Mr. Sujith R,Dr. R. Ishwarya
Publisher : Academic Guru Publishing House
Page : 219 pages
File Size : 45,7 Mb
Release : 2024-07-03
Category : Young Adult Nonfiction
ISBN : 9788196241476

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Medical Microbiology by Dr. Anusha G,Dr. Maheshwary D,Mr. Sujith R,Dr. R. Ishwarya Pdf

The development of microorganisms poses a significant problem for the contemporary medical system and for public health. Since viruses like influenza, HIV, TB, malaria, and SARS are always changing, maintaining monitoring and gaining knowledge into the underlying mechanism is essential. In the field of medical microbiology, study the composition, diversity, and behaviors of microorganisms, as well as how they have an effect on human health and well-being, especially as infectious agents. Epidemiology as well as the biology of microorganisms are both broken down in great depth in the field of medical microbiology. It examines the factors that contribute to the pathogenicity & virulence in microbial organisms. It examines the innate propensity for sensitivity to antimicrobial agents or immunity to such drugs. The categorization of Neisseriaceae as well as its clinical significance are completely explored. There is an extensive discussion on both the definition of haemophiles and its infectious potential. This book provides an in-depth discussion on the categorization of spiral bacteria as well as their therapeutic significance. The process of isolating fungus as well as identifying them is explained in its entirety. The laboratory & serological diagnosis for systemic fungal infections are discussed in this book. The principles of microbiology & immunology are presented in an interesting way that is both clear and concise throughout this condensed and user-friendly book.

Author : Tomris Özben,Mordechai Chevion
Publisher : IOS Press
Page : 304 pages
File Size : 49,9 Mb
Release : 2004
Category : Brain
ISBN : 1586034286

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Frontiers in Neurodegenerative Disorders and Aging by Tomris Özben,Mordechai Chevion Pdf