Fast Facts Lymphoma

Author : P.L. Haun,J.J. Scarisbrick
Publisher : Karger Medical and Scientific Publishers
Page : 112 pages
File Size : 43,5 Mb
Release : 2019-04-25
Category : Medical
ISBN : 9781912776313

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Fast Facts: Cutaneous T-cell Lymphoma by P.L. Haun,J.J. Scarisbrick Pdf

Cutaneous T-cell lymphoma (CTCL) has been described as a 'great mimicker'. The correct diagnosis hinges on effective collaboration between clinicians and pathologists to correlate pathological and clinical findings. The patient's history, lesion description and diagnostic work-up will help the pathologist interpret the histopathology, whilst the clinician’s diagnosis is aided by a clear understanding the terminology used in the pathology report. The treatment of early and advanced mycosis fungoides and its variants is potentially lifelong, with patients typically cycling among treatments, interspersed with periods of expectant therapy providing palliation and symptomatic relief. Effective management requires knowledge of the wide range of options, how they are used, and their side-effect profile, in order to tailor treatment to the individual patient. ' Fast Facts: Cutaneous T-Cell Lymphoma' is designed to help primary care providers, dermatologists, and oncologists to communicate effectively with pathologists in the diagnosis of this chronic condition, aided by over 100 superb clinical and pathological images, and to provide tailored long-term care for their patients. This concise, practical handbook will ensure clear communication with respect to the clinical presentation, histopathology, immunophenotyping and treatment of: • early and advanced mycosis fungoides and its variants • Sézary syndrome • other non-mycosis fungoides CTCLs. It is essential reading for pathologists, non-specialist clinicians and dermatology and oncology trainees.

Author : C. Hatton,G. Collins,J. Sweetenham
Publisher : Karger Medical and Scientific Publishers
Page : 161 pages
File Size : 45,5 Mb
Release : 2018-10-16
Category : Medical
ISBN : 9781910797952

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Fast Facts: Lymphoma by C. Hatton,G. Collins,J. Sweetenham Pdf

Lymphoma affects all ages. Advances in diagnostic cellular and molecular techniques coupled with new treatment options are improving patient outcomes. This third edition of our bestselling 'Fast Facts: Lymphoma' distills the most important aspects of diagnosis and management into an up-to-date and highly accessible well-illustrated overview that includes: • a clear outline of the nature of lymphoma • the essentials of clinical presentation, biopsy and histology • a synopsis of current laboratory diagnostics, including immunophenotyping, cytogenetics and microarray technology, and updated to include the latest molecular genetic techniques • key aspects of staging and initial therapy • clearly illustrated overviews of the pathology, presentation, treatment and prognosis of each lymphoma subtype • new treatment options, including targeted biological therapies and chimeric antigen receptor T cells (CAR T cells) • a practical overview of supportive care for the complications of lymphoma. Written by three lymphoma experts from the UK and USA, 'Fast Facts: Lymphoma' gives an interesting international perspective to this challenging disease. Its clarity and colorful format make it a valuable resource for senior health professionals seeking an accessible update in this area of hemato-oncology, trainee doctors and specialist nurses who are new to it, and individuals affected by lymphoma and seeking more information. Contents: • Epidemiology • Cellular and molecular aspects • Presentation, biopsy and diagnostic laboratory techniques • Staging and general management principles • Aggressive B-cell lymphomas • Indolent B-cell lymphomas • T-cell and natural-killer cell lymphomas • Immunocompromised and HIV-positive patients • Hodgkin lymphoma • Treatment modalities • Supportive care

Author : Chris Hatton,Graham Collins,John Sweetenham
Publisher : Karger Medical and Scientific Publishers
Page : 142 pages
File Size : 54,9 Mb
Release : 2018-10-16
Category : Medical
ISBN : 9781910797945

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Fast Facts: Lymphoma by Chris Hatton,Graham Collins,John Sweetenham Pdf

Lymphoma affects all ages. Advances in diagnostic cellular and molecular techniques coupled with new treatment options are improving patient outcomes. This third edition of our bestselling 'Fast Facts: Lymphoma' distills the most important aspects of diagnosis and management into an up-to-date and highly accessible well-illustrated overview that includes: • a clear outline of the nature of lymphoma • the essentials of clinical presentation, biopsy and histology • a synopsis of current laboratory diagnostics, including immunophenotyping, cytogenetics and microarray technology, and updated to include the latest molecular genetic techniques • key aspects of staging and initial therapy • clearly illustrated overviews of the pathology, presentation, treatment and prognosis of each lymphoma subtype • new treatment options, including targeted biological therapies and chimeric antigen receptor T cells (CAR T cells) • a practical overview of supportive care for the complications of lymphoma. Written by three lymphoma experts from the UK and USA, 'Fast Facts: Lymphoma' gives an interesting international perspective to this challenging disease. Its clarity and colorful format make it a valuable resource for senior health professionals seeking an accessible update in this area of hemato-oncology, trainee doctors and specialist nurses who are new to it, and individuals affected by lymphoma and seeking more information. Contents: • Epidemiology • Cellular and molecular aspects • Presentation, biopsy and diagnostic laboratory techniques • Staging and general management principles • Aggressive B-cell lymphomas • Indolent B-cell lymphomas • T-cell and natural-killer cell lymphomas • Immunocompromised and HIV-positive patients • Hodgkin lymphoma • Treatment modalities • Supportive care

Author : Graham P. Collins,Toby A. Eyre,Eliza Hawkes
Publisher : Karger Medical and Scientific Publishers
Page : 188 pages
File Size : 54,7 Mb
Release : 2023-07-20
Category : Medical
ISBN : 9783318072860

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Fast Facts: Lymphoma by Graham P. Collins,Toby A. Eyre,Eliza Hawkes Pdf

Lymphoma can be broadly defined as a cancer of mature lymphocytes. Our understanding of the biology of normal lymphocytes and lymphoma has grown at a tremendous pace, and this is now directly translating into changes in clinical practice. This became evident with the introduction of one of the first therapeutic monoclonal antibodies into cancer medicine, the CD20-directed antibody rituximab, which has led to significant benefit for patients with B-cell lymphomas. Since then, a raft of novel agents has entered clinical practice, including targeted small molecules, antibody-drug conjugates, bispecific antibodies, and chimeric antigen receptor (CAR) T cells. This new edition of 'Fast Facts: Lymphoma' has been updated to include recent changes in our understanding of lymphoma biology as well as improvements in diagnostics and therapeutics.

Author : Foss, Francine,Ahearne, Matthew,Fox, Christopher P.
Publisher : Karger Medical and Scientific Publishers
Page : 101 pages
File Size : 52,5 Mb
Release : 2019-06-20
Category : Medical
ISBN : 9781912776184

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Fast Facts: Peripheral T-cell Lymphoma by Foss, Francine,Ahearne, Matthew,Fox, Christopher P. Pdf

The peripheral T-cell lymphomas (PTCLs) are a heterogenous group of rare entities. Whilst cytogenetic and molecular identifiers are being identified, accurate diagnosis remains challenging, requiring careful, expert integration of the clinical and pathological findings. The treatment of PTCL is also challenging. Protocols for the different subtypes are only just beginning to emerge, hindered by the complexities of conducting trials in such uncommon and varied conditions. While first-line treatment with conventional chemotherapy is seldom curative, patients who achieve remission may be eligible for stem cell transplantation, offering the possibility of long-term disease control if not cure. Targeted biologics are also being developed as unique cytotoxic markers are identified. 'Fast Facts: Peripheral T-Cell Lymphomas' is a new title in the Fast Facts extensive hemato-oncology library, written by experts in this emerging field. This handbook will be useful to anyone involved in the care of patients with PTCL, including haematologists, oncologists, specialist nurses and primary care providers, raising awareness of these rare lymphomas and the current – and emerging – approaches to diagnosis and treatment.

Author : Paul L Haun,Julia J Scarisbrick
Publisher : Karger Medical and Scientific Publishers
Page : 112 pages
File Size : 55,5 Mb
Release : 2019-04-25
Category : Lymphomas
ISBN : 9781912776306

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Fast Facts: Cutaneous T-cell Lymphoma by Paul L Haun,Julia J Scarisbrick Pdf

Cutaneous T-cell lymphoma (CTCL) has been described as a 'great mimicker'. The correct diagnosis hinges on effective collaboration between clinicians and pathologists to correlate pathological and clinical findings. The patient's history, lesion description and diagnostic work-up will help the pathologist interpret the histopathology, whilst the clinician’s diagnosis is aided by a clear understanding the terminology used in the pathology report. The treatment of early and advanced mycosis fungoides and its variants is potentially lifelong, with patients typically cycling among treatments, interspersed with periods of expectant therapy providing palliation and symptomatic relief. Effective management requires knowledge of the wide range of options, how they are used, and their side-effect profile, in order to tailor treatment to the individual patient.

Author : Chris Hatton,Graham Collins,John Sweetenham
Publisher : Karger Medical and Scientific Publishers
Page : 142 pages
File Size : 44,6 Mb
Release : 2014-10-31
Category : Medical
ISBN : 9781908541772

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Fast Facts: Lymphoma by Chris Hatton,Graham Collins,John Sweetenham Pdf

Hodgkin lymphoma and the many different subtypes of non-Hodgkin lymphoma (NHL) have different responses to treatment, so accurate diagnosis and a rational approach to management are essential. 'Fast Facts: Lymphoma' distills the most important aspects of the diagnosis and management of these complex disorders into a highly accessible well-illustrated summary of the key facts. This fully updated second edition provides: • a clear outline of the nature of lymphoma • the essentials of clinical presentation, biopsy and basic histology • the latest laboratory diagnostics, including immunophenotyping, cytogenetics and microarray technology • key aspects of staging and initial therapy • superbly illustrated overviews of the pathology, presentation, treatment and prognosis of each lymphoma subtype • new treatment options, including targeted biological therapies • a practical overview of supportive care for the complications of lymphoma Written by three experts in the field from the UK and USA, 'Fast Facts: Lymphoma' applies an international perspective to this challenging disease in a unique format within the context of clinical practice. It is a valuable resource for trainee doctors and specialist nurses working in the field of hemato-oncology. It will also be of interest to the inquiring patient or carer who wishes to know more about lymphoma. Contents: • Epidemiology • Cellular and molecular aspects • Presentation, biopsy and diagnostic laboratory techniques • Staging and general management principles • Aggressive B-cell lymphomas • Indolent B-cell lymphomas • T-cell and natural-killer cell lymphomas • Immunocompromised and HIV-positive patients • Hodgkin lymphoma • Treatment modalities • Supportive care

Author : Chris Hatton (Hematologist),Graham Collins (Hematologist),J. W. Sweetenham
Publisher : Unknown
Page : 0 pages
File Size : 42,5 Mb
Release : 2014
Category : Electronic
ISBN : 1908541784

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Lymphoma by Chris Hatton (Hematologist),Graham Collins (Hematologist),J. W. Sweetenham Pdf

Author : Owen A. O'Connor,Won Seog Kim,Pier L. Zinzani
Publisher : John Wiley & Sons
Page : 434 pages
File Size : 50,9 Mb
Release : 2021-06-01
Category : Medical
ISBN : 9781119671312

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The Peripheral T-Cell Lymphomas by Owen A. O'Connor,Won Seog Kim,Pier L. Zinzani Pdf

THE PERIPHERAL T-CELL LYMPHOMAS Provides a comprehensive look at Peripheral T-Cell lymphomas, including the group’s unique geographic distribution, underlying genetics, and novel treatments Peripheral T-Cell lymphomas (PTCL) are a diverse group of lymphoid malignancies that develop from mature T cells and natural killer (NK) cells. PTCL represent 10-15% of all cases of non-Hodgkin lymphoma in the US, and up to 20-25% of cases in South America, Asia, and other regions around the world. The role of different etiologic factors and the variation of geographic distribution makes PTCL one of the most difficult types of cancer to understand and treat. For the first time in a single volume, The Peripheral T-Cell Lymphomas presents a comprehensive survey of this complex and rare group of blood cancers. Featuring contributions from an international team of leading authorities in the various aspects of PTCL, this authoritative text covers biology, epidemiology, classification, approved and emerging drugs, molecular genetics, and more. Detailed clinical chapters address diagnosis, prognosis, and treatment of each of the major PTCL subtypes identified in the 2018 WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues. This much-needed resource: Covers the biological basis, epidemiology, classification, and treatment of PTCL Discusses the future of the field, including global collaboration efforts and novel approaches to PCTL Explores the role of biologics in PTCL and autologous and allogeneic stem-cell transplantation Offers new insights on molecular pathogenesis, innovative therapeutics, and novel drug combinations Features contributions from the Chairs The T-Cell Lymphoma Forum: the world’s largest meeting focused on PTCL Reflecting the unique epidemiology and genetic diversity of the PTCL, The Peripheral T-Cell Lymphomas is an indispensable source of data, insight, and references for the medical community, particularly oncologists and hematologists in both training and practice.

Author : Paul L. Haun,Julia J. Scarisbrick
Publisher : Karger Medical and Scientific Publishers
Page : 98 pages
File Size : 47,9 Mb
Release : 2016-08-18
Category : Medical
ISBN : 9781910797204

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Fast Facts: Diagnosing Cutaneous T-Cell Lymphoma by Paul L. Haun,Julia J. Scarisbrick Pdf

Cutaneous T-cell lymphoma (CTCL) is one of the 'great mimickers'. To be certain of the diagnosis, there must be clear correlation between the pathological and clinical findings, making collaboration between clinicians and pathologists essential. Knowing the patient's history, lesion description and diagnostic work-up will help the pathologist make a more informed decision with respect to the histopathology under the microscope. Likewise, understanding the terminology used in the pathology report will improve the clarity of the clinician’s diagnosis. 'Fast Facts: Diagnosing Cutaneous T-Cell Lymphoma' is designed to help primary care providers, dermatologists and pathologists speak the same language. With over 100 superb clinical and pathological images, this concise, practical handbook will ensure clear communication with respect to the clinical presentation, histopathology and immunophenotyping of: • early and advanced mycosis fungoides and its variants • Sézary syndrome • other non-mycosis fungoides CTCLs. It is therefore essential reading for all pathologists, non-specialist clinicians and dermatology trainees.

Author : Geoffrey Holmes,Carlo Catassi,Alessio Fasano
Publisher : Karger Medical and Scientific Publishers
Page : 130 pages
File Size : 51,6 Mb
Release : 2009-08-01
Category : Medical
ISBN : 9781905832569

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Fast Facts: Celiac Disease by Geoffrey Holmes,Carlo Catassi,Alessio Fasano Pdf

Remarkable progress has been made in our knowledge of celiac disease, yet the diagnosis is often overlooked. The practical challenge for healthcare professionals is to identify the disease and offer patients a gluten-free diet that will restore most to full health and help to prevent further complications. This comprehensively revised second edition of 'Fast Facts: Celiac Disease', written by three international experts, considers: • Celiac disease in all its forms - typical, atypical, silent, potential and latent • Gluten sensitivity, genetic risk and predisposing physiological abnormalities • The variable presentation of disease in both adults and children • Associated immune disorders • The puzzle of diagnosis, solved by clinical, serological, histological and genetic investigation • Troublesome, and sometimes life-threatening, non-malignant complications • The close links between celiac disease and dermatitis herpetiformis • The risk of malignancy, its treatment and prognosis • Management with a gluten-free diet, and the emotional and social implications of the diet • Potential new therapies Highly readable with informative illustrations, 'Fast Facts: Celiac Disease' provides an up-to-date account of this common yet easily missed condition. It is an excellent clinical resource for the primary care team, gastroenterologists in training and anyone who wants to know more about this challenging disease. Contents: • Definition • Epidemiology • Pathophysiology • Clinical manifestations • Diagnosis • Non-malignant complications • Dermatitis herpetiformis • Malignant complications • Management • Future trends • Useful resources

Author : R.J. Buka,D. Moloney
Publisher : Karger Medical and Scientific Publishers
Page : 95 pages
File Size : 54,9 Mb
Release : 2021-09-30
Category : Medical
ISBN : 9783318069358

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Fast Facts: CAR T-Cell Therapy in Diffuse Large B-Cell Lymphoma by R.J. Buka,D. Moloney Pdf

Diffuse large B-cell lymphoma (DLBCL) is the most common form of high-grade non-Hodgkin lymphoma. While treatment with immunochemotherapy has generally shown good outcomes, specific subgroups of patients with high-risk disease have an unfavorable prognosis. Extensive efforts have been made to improve outcomes in these patients. As such, CD19-targeted chimeric antigen receptor (CAR) T-cell therapy has become the new standard of care for patients with relapsed or refractory DLBCL after at least two prior lines of therapy. It is an exciting new therapeutic intervention that is integral to the concept of personalized medicine. Table of Contents: • DLBCL: an overview • CAR T cells • CAR T-cell products • Delivering CAR T-cell therapy and managing patient expectations • CAR T-cell therapy-related toxicities

Author : Elizabeth M. Adler
Publisher : JHU Press
Page : 477 pages
File Size : 40,5 Mb
Release : 2016-02-01
Category : Medical
ISBN : 9781421418117

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Living with Lymphoma by Elizabeth M. Adler Pdf

The second edition of this award-winning guide reflects profound shifts in the lymphoma landscape, including new treatments that are extending survival. Winner, American Medical Writers Association Medical Book Award When neurobiologist Elizabeth M. Adler was diagnosed with non-Hodgkin lymphoma almost twenty years ago, she learned everything she could about the disease, both to cope with the emotional stress of her diagnosis and to make the best possible decisions for her treatment. In Living with Lymphoma, she combines her scientific expertise and personal knowledge with a desire to help other people who have lymphoma manage this complex and often baffling disease. With the availability of more effective treatment regimens, many people with lymphoma are living longer; in fact, there are more than 700,000 lymphoma survivors in the United States alone. Given this change in the lymphoma landscape, the second edition of this book places a greater emphasis on survivorship. The new edition includes the latest information on lymphoma diagnosis, treatment, and incidence and describes the most recent update to the WHO system of lymphoma classification and staging. Adler discusses new targeted therapies like ibrutinib and idelalisib and describes how other treatments, including radiation therapy and stem cell transplants, have been modified while others have been discontinued. She also addresses new developments, such as the possible role of lack of sunlight and vitamin D in the pathogenesis of lymphoma, and the use of medical marijuana. The book includes suggestions for further reading, including the latest material available online.

Author : Gilbert H. Daniels,Colin M. Dayan
Publisher : Karger Medical and Scientific Publishers
Page : 146 pages
File Size : 54,9 Mb
Release : 2006-01-01
Category : Medical
ISBN : 9781903734650

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Fast Facts: Thyroid Disorders by Gilbert H. Daniels,Colin M. Dayan Pdf

Abnormalities of thyroid function rival diabetes mellitus in terms of prevalence and can affect any system in the body. In the UK and North America it is estimated that palpable thyroid nodules are present in 1 in 20 of the population, and in the UK alone 20,000 tests are carried out each year in clinical chemistry laboratories. Thus, all doctors can expect to encounter thyroid disease in one form or another. Thyroid disorders are generally very responsive to treatment, but there are traps for the unwary - not least because of the frequent atypical presentations and the widespread prevalence of subclinical disease. 'Fast Facts: Thyroid Disorders' is written by two leading experts of international standing who share a wealth of clinical and research experience. The text, which is comprehensively illustrated to make core clinical information easily accessible, is a concise and practical guide for all who manage patients with these common conditions. • A concise guide to the recognition of thyroid disorders and the selection of appropriate thyroid function tests • Provides expert advice on when to test, when to treat and when to refer, ensuring rapid initiation of appropriate therapy • Highlights the particular challenges posed by thyroid disease during pregnancy • Covers the management of thyroid eye conditions • Sound, dependable advice for the healthcare team and patient in coping with these common conditions Contents: • Glossary • Introduction • Thyroid physiology and function tests • Hyperthyroidism: etiology and presentation • Hyperthyroidism: diagnosis and management • Hypothyroidism: etiology and presentation • Hypothyroidism: diagnosis and management • Pregnancy and the thyroid • Thyroid nodules and thyroid cancer

Author : Antonio Subtil
Publisher : Springer
Page : 320 pages
File Size : 45,6 Mb
Release : 2019-03-25
Category : Medical
ISBN : 9783030116545

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Diagnosis of Cutaneous Lymphoid Infiltrates by Antonio Subtil Pdf

This volume is the first of its kind to emphasize the visual approach in the diagnosis of cutaneous lymphoid infiltrates. Written and designed in an accessible yet highly detailed format by an expert in the field, this book bridges the knowledge gaps so often found when dealing with skin lymphomas. Complete with more than two hundred high quality images and illustrations, Diagnosis of Cutaneous Lymphoid Infiltrates offers pearls and pitfalls as well as differential diagnoses. Additionally, images are explained and decoded with the use of illustrations and analogies, proving to be an invaluable resource for pathologists, dermatologists, dermatopathologists, hematopathologists, and residents and fellows in these fields.