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Flavins and Flavoproteins 1996 by Charles Haddon Williams Pdf
This publication, a collection of 174 papers, encompasses the fundamental and intricate photochemistry and electron transfer of flavins and flavoproteins, the mechanisms associated with enzymes utilising flavins (such as dehydrogenases, reductases, oxidases, monooxygenases, synthases, peroxidases), the three-dimensional structures of flavoproteins and flavoenzymes and the emerging role of flavins and flavoproteins in medicine. Flavins and Flavoproteins 1996 continues the series which has appeared every three years since 1965. Presented are overviews of key areas of flavin research, coupled with the most recent understanding of the chemistry/photochemistry of flavins and the structure/function relationship of numerous proteins/enzymes that use flavins as essential cofactors. Key Features: Detailed studies on the structure and mechanism of flavoenzymes are reported together with newly discovered medical aspects; New research of high quality with extensive data, figures and bibliographies; The interaction of flavins with other electron carriers such as the cytochromes, metals, and non-heme iron centres is investigated with a variety of spectrophotometric techniques; NMR and crystallography studies have provided new three-dimensional structures of several flavoenzymes and flavoproteins; Numerous papers on an extensive number of flavoenzymes and complex flavoproteins are presented.
Flavins and flavoproteins are a widely investigated and highly versatile group of compounds. Participation of these compounds in photochemistry and photobiology processes are of particular importance in the fields of biology, chemistry and medicine. Written by leading experts in the field each section of the book includes a historical overview of the subject, state of the art developments and future perspectives. Flavins: Photochemistry and Photobiology begins with the properties and applications of flavins, including their photochemistry in aqueous and organic solutions. Subsequent sections discuss riboflavin as a visible light sensitizer in the photo degradation of drugs, antiviral and antibacterial effects, the role of flavins in light induced toxicity and blue light initiated DNA repair by photolyase. Finally there are sections on the flavin based photoreceptors in plants, bacteria and eukaryotic photosynthetic flagelettes. This book brings together leading experts with a unique interdisciplinary emphasis, to provide an authoritative resource on flavins and their role in photochemistry and photobiology.
Complex Flavoproteins, Dehydrogenases and Physical Methods by Anonim Pdf
The dynamic field of flavin and flavoprotein biochemistry has seen rapid advancement in recent years. This comprehensive two volume set provides an overview of all aspects of contemporary research in this important class of enzymes. Topics treated include flavoproteins involved in energy generation, signal transduction and electron transfer (including respiration); oxygen activation by flavoproteins; the biology and biochemistry of complex flavoproteins; flavin and flavoprotein photochemistry/photophysics as well as biotechnological applications of flavoproteins. Recent developments in this field include new structures (including those of large membrane-integral electron transfer complexes containing FMN or FAD), elucidation of the role of flavoproteins in cell signalling pathways (including both phototaxis and the circadian cycle) and important new insights into the reaction mechanisms of flavin-containing enzymes. This volume focusing on complex flavoproteins and physical methods is an essential reference for all researchers in biochemistry, chemistry, photochemistry and photophysics working on flavoenzymes.
Flavin-based Catalysis by Radek Cibulka,Marco W. Fraaije Pdf
The book gives a unique overview of this rapidly developing research field, presenting structures and properties of flavin derivatives as well as their proven application as bioinspired catalysts in various organocatalytic, biocatalytic, and photocatalytic reactions.
Flavins and Flavoproteins 1996 by Charles Haddon Williams Pdf
This publication, a collection of 174 papers, encompasses the fundamental and intricate photochemistry and electron transfer of flavins and flavoproteins, the mechanisms associated with enzymes utilising flavins (such as dehydrogenases, reductases, oxidases, monooxygenases, synthases, peroxidases), the three-dimensional structures of flavoproteins and flavoenzymes and the emerging role of flavins and flavoproteins in medicine. Flavins and Flavoproteins 1996 continues the series which has appeared every three years since 1965. Presented are overviews of key areas of flavin research, coupled with the most recent understanding of the chemistry/photochemistry of flavins and the structure/function relationship of numerous proteins/enzymes that use flavins as essential cofactors. Key Features: Detailed studies on the structure and mechanism of flavoenzymes are reported together with newly discovered medical aspects; New research of high quality with extensive data, figures and bibliographies; The interaction of flavins with other electron carriers such as the cytochromes, metals, and non-heme iron centres is investigated with a variety of spectrophotometric techniques; NMR and crystallography studies have provided new three-dimensional structures of several flavoenzymes and flavoproteins; Numerous papers on an extensive number of flavoenzymes and complex flavoproteins are presented.
Alpha-Keto Acid Dehydrogenase Complexes by M.S. Patel,T.E. Roche,R.A. Harris Pdf
Found in all organisms, the alpha-keto acid dehydrogenase complexes have central roles in cellular metabolism and are major sites of regulation. The understanding of the organization, function and regulation of these quintessential multienzyme complexes has been greatly advanced by studies employing molecular biology and biophysical techniques. Although these enzyme systems have some features in common, their diversity in fulfilling unique organism - or tissue - specific roles is truly amazing. These systems have medical importance in areas ranging from defects in regulation (linked to diabetes, heart disease, obesity, nutrition defects), to inherited diseases (inborn errors, maple syrup urine disease) to acquired immune diseases (primary biliary cirrhosis). This book brings together wide-ranging recent findings on the structure(function relationships, gene regulation, and genetic defects of the alpha-keto acid dehydrogenase complexes, namely the pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase and the branched-chain alpha-keto acid dehydrogenase complexes. A wide variety of experimental approaches together with new results presented in this book should serve as a resource for beginning to established investigators in the field as well as scientists who are interested in mitochondria, dehydrogenases, kinases, phosphatases, lipoic acid, thiamine pyrophosphate, and enzyme complexes.
Flavin-Dependent Enzymes: Mechanisms, Structures and Applications by Anonim Pdf
The Enzymes, Volume 47, highlights new advances in the field, with this new volume presenting interesting chapters on The Multipurpose Family of Oxidases, Vanillyl alcohol oxidase, Choline oxidases, Aryl alcohol oxidase, D- and L-amino acid oxidases, Sugar oxidases, Phenolic Compounds hydroxylases, Baeyer-Villiger Monooxygenases, Flavin-dependent halogenases, Flavin-dependent dehalogenases, Styrene Monooxygenases, Bacterial luciferases, Cellobiose Dehydrogenases, Prenylated flavoenzymes, Ene-reductases, Flavoenzymes in Biocatalysis. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in The Enzymes series
FLAVINS and FLAVOPROTEINS 2011 by Susan Miller,Russ Hille,Bruce Palfey Pdf
This book contains articles based on oral and poster presentations at the 17th International Symposium on Flavins and Flavoproteins, which was held July 24-29, 2011 at the University of California Berkeley in the USA. These triennial conferences highlight the latest advances in the field and the conference proceedings book serves both as documentation of the event and as a reference.
This book summarizes recent advances made in the biophysics, biochemistry, and molecular biology of the enzyme known as Photosystem I, the light-induced plastocyanin: ferredoxin oxidoreductase. The volume provides a unique compilation of chapters that includes information highlighting controversial issues to indicate the frontiers of research and places special emphasis on methodology and practice for new researchers.