Fluoxetine

Author : Graziano Pinna
Publisher : Unknown
Page : 412 pages
File Size : 41,9 Mb
Release : 2015-04-01
Category : Electronic
ISBN : 1634820762

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Fluoxetine by Graziano Pinna Pdf

Fluoxetine, best known by the trade name Prozac®, unlike other psychotropic drugs whose effects were serendipitously stumbled upon, was the first developed for a precise mechanism of action, that is, the ability to selectively inhibit serotonin reuptake, based upon the theory that increasing the availability of serotonin would treat major depression. Once approved by the FDA in 1987, fluoxetine quickly became the most prescribed psychotropic drug worldwide and its success in improving mood disorders has triggered the development of a large number of congener molecules, commonly known as SSRIs after their purported mechanism of action. However, a quarter of a century after its development, the idea that fluoxetine asserts its positive behavioral effect through inhibition of serotonergic reuptake is not firmly established. This book reviews several preclinical and clinical reports suggesting that the pharmacological effects of fluoxetine may be mediated by means other than the regulation of serotonin, including the regulation of gene expression, modifying epigenetic mechanisms as well as modifying microRNAs. One of the most prominent mechanisms for the therapeutic relevance of fluoxetine relates to influencing neuroplasticity by enhancing neurotropic factors, including BDNF signaling and altering adult neurogenesis. The ability of fluoxetine to rapidly increase neurosteroid levels accounts for the fast anxiolytic effects of this drug. Fluoxetine action at sigma-1 receptor or modulating glutamatergic neurotransmission as well as the combination of fluoxetine with other psychotropic drugs is discussed in relation to its therapeutic effects. While fluoxetine was primarily prescribed as an antidepressant, this drug currently represents a treatment of choice for a broad spectrum of psychiatric disorders, including post-traumatic stress disorder and a range of anxiety disorders. This drug even possesses analgesic actions and is a valuable therapy for stroke. This book also highlights emerging evidence on the gender-specific effects of fluoxetine, its potential adverse features, including its addiction liability in combination with psychostimulants, and the impact of perinatal fluoxetine exposure.

Author : Anonim
Publisher : Academic Press
Page : 288 pages
File Size : 47,5 Mb
Release : 2019-07-13
Category : Medical
ISBN : 9780128173176

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Drug-Induced Liver Injury by Anonim Pdf

Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series

Author : Charles D. Ciccone
Publisher : F.A. Davis
Page : 1217 pages
File Size : 45,7 Mb
Release : 2013-03-21
Category : Medical
ISBN : 9780803640047

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Davis's Drug Guide for Rehabilitation Professionals by Charles D. Ciccone Pdf

A one-of-a-kind guide specifically for rehabilitation specialists! A leader in pharmacology and rehabilitation, Charles Ciccone, PT, PhD offers a concise, easy-to-access resource that delivers the drug information rehabilitation specialists need to know. Organized alphabetically by generic name, over 800 drug monographs offer the most up-to-date information on drug indications, therapeutic effects, potential adverse reactions, and much more! A list of implications for physical therapy at the end of each monograph helps you provide the best possible care for your patients. It’s the perfect companion to Pharmacology in Rehabilitation, 4th Edition!

Author : David Healy
Publisher : NYU Press
Page : 367 pages
File Size : 40,6 Mb
Release : 2006-10
Category : Medical
ISBN : 9780814736975

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Let Them Eat Prozac by David Healy Pdf

A psychiatrist provides an insider account on the controversial use of selective serotonin reuptake inhibitors (SSRIs) Prozac. Paxil. Zoloft. Turn on your television and you are likely to see a commercial for one of the many selective serotonin reuptake inhibitors (SSRIs) on the market. We hear a lot about them, but do we really understand how these drugs work and what risks are involved for anyone who uses them? Let Them Eat Prozac explores the history of SSRIs—from their early development to their latest marketing campaigns—and the controversies that surround them. Initially, they seemed like wonder drugs for those with mild to moderate depression. When Prozac was released in the late 1980s, David Healy was among the psychiatrists who prescribed it. But he soon observed that some of these patients became agitated and even attempted suicide. Could the new wonder drug actually be making patients worse? Healy draws on his own research and expertise to demonstrate the potential hazards associated with these drugs. He intersperses case histories with insider accounts of the research leading to the development and approval of SSRIs as a treatment for depression. Let Them Eat Prozac clearly demonstrates that the problems go much deeper than a side-effect of a particular drug. The pharmaceutical industry would like us to believe that SSRIs can safely treat depression, anxiety, and a host of other mental problems. But, as Let Them Eat Prozac reveals, this “cure” may be worse than the disease.

Author : Joseph Glenmullen
Publisher : Simon and Schuster
Page : 388 pages
File Size : 46,5 Mb
Release : 2001-04-17
Category : Family & Relationships
ISBN : 9780743200622

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Prozac Backlash by Joseph Glenmullen Pdf

In a controversial look at the potent drugs millions of Americans consume each day--for everything from anxiety to sexual addiction--Dr. Glenmullen presents authoritative information on why they are risky and provides advice on choosing safer alternative treatments.

Author : Katherine J. Aitchison,Robin M. Murray,Patrick J. Power,Eva M. Tsapakis
Publisher : CRC Press
Page : 152 pages
File Size : 46,6 Mb
Release : 2022-03-26
Category : Medical
ISBN : 9780429524141

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First Episode Psychosis by Katherine J. Aitchison,Robin M. Murray,Patrick J. Power,Eva M. Tsapakis Pdf

The new edition of this popular handbook has been thoroughly updated to include the latest data concerning treatment of first-episode patients. Drawing from their experience, the authors discuss the presentation and assessment of the first psychotic episode and review the appropriate use of antipsychotic agents and psychosocial approaches in effective management. This is an authoritative text written by a team of highly respected authors for psychiatrists, neurologists, primary care practitioners and health care professional working in psychiatry. Drawing from their experience, the presentation and assessment of the first psychotic episode are discussed, details regarding antipsychotic drugs and their appropriate use are reviewed and psychosocial approaches are examined. The resulting book offers a concise and valuable guide to those wishing to review the latest proposals for the treatment of first-episode psychosis supported by up-to-date references, in a single publication.

Author : Peter D. Kramer
Publisher : Penguin
Page : 481 pages
File Size : 52,7 Mb
Release : 1997-09-01
Category : Psychology
ISBN : 9780140266719

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Listening to Prozac by Peter D. Kramer Pdf

The New York Times bestselling examination of the revolutionary antidepressant, with a new introduction and afterword reflecting on Prozac’s legacy and the latest medical research “Peter Kramer is an analyst of exceptional sensitivity and insight. To read his prose on virtually any subject is to be provoked, enthralled, illuminated.” —Joyce Carol Oates When antidepressants like Prozac first became available, Peter D. Kramer prescribed them, only to hear patients say that on medication, they felt different—less ill at ease, more like the person they had always imagined themselves to be. Referencing disciplines from cellular biology to animal ethology, Dr. Kramer worked to explain these reports. The result was Listening to Prozac, a revolutionary book that offered new perspectives on antidepressants, mood disorders, and our understanding of the self—and that became an instant national and international bestseller. In this thirtieth anniversary edition, Dr. Kramer looks back at the influence of his groundbreaking book, traces progress in the relevant sciences, follows trends in the use and public understanding of antidepressants, and assesses potential breakthroughs in the treatment of depression. The new introduction and afterword reinforce and reinvigorate a book that the New York Times called “originally insightful” and “intelligent and informative,” a window on a medicine that is “telling us new things about the chemistry of human character.”

Author : Dr Katharine Phillips
Publisher : Oxford University Press
Page : 608 pages
File Size : 55,6 Mb
Release : 2017-07-12
Category : Medical
ISBN : 9780190254155

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Body Dysmorphic Disorder by Dr Katharine Phillips Pdf

This landmark book is the first comprehensive edited volume on body dysmorphic disorder (BDD), a common and severe disorder. People with BDD are preoccupied with distressing or impairing preoccupations with non-existent or slight defects in their physical appearance. People with BDD think that they look ugly -- even monstrous -- although they look normal to others. BDD often derails sufferers' lives and can lead to suicide. BDD has been described around the world since the 1800s but was virtually unknown and unstudied until only several decades ago. Since then, research on BDD has dramatically increased understanding of this often-debilitating condition. Only recently, BDD was considered untreatable, but today, most sufferers can be successfully treated. This is the only book that provides comprehensive, in-depth, up-to-date information on BDD's clinical features, history, classification, epidemiology, morbidity, features in special populations, diagnosis and assessment, etiology and pathophysiology, treatment, and relationship to other disorders. Numerous chapters focus on cosmetic treatment, because it is frequently received but usually ineffective for BDD, which can lead to legal action and even violence toward treating clinicians. The book includes numerous clinical cases, which illustrate BDD's clinical features, its often-profound consequences, and recommended treatment approaches. This volume's contributors are the leading researchers and clinicians in this rapidly expanding field. Editor Katharine A. Phillips, head of the DSM-V committee on BDD, has done pioneering research on many aspects of this disorder, including its treatment. This book will be of interest to all clinicians who provide mental health treatment and to researchers in BDD, anxiety disorders, eating disorders, and other obsessive-compulsive and related disorders. It will be indispensable to surgeons, dermatologists, and other clinicians who provide cosmetic treatment. Students and trainees with an interest in psychology and mental health will also be interested in this book. This book fills a major gap in the literature by providing clinicians and researchers with cutting-edge, indispensable information on all aspects of BDD and its treatment.

Author : Joe Kossowsky,Mirko Manchia
Publisher : Frontiers Media SA
Page : 149 pages
File Size : 50,9 Mb
Release : 2023-05-18
Category : Medical
ISBN : 9782832523766

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Systematic Reviews of Pharmacological and Non-Pharmacological Psychiatric Interventions by Joe Kossowsky,Mirko Manchia Pdf

Author : Louis A. Pagliaro,Ann Marie Pagliaro
Publisher : Routledge
Page : 732 pages
File Size : 40,9 Mb
Release : 2020-03-26
Category : Psychology
ISBN : 9781317838753

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Psychologists' Psychotropic Drug Reference by Louis A. Pagliaro,Ann Marie Pagliaro Pdf

First published in 1998. The purpose of this book is to provide prescribing psychologists and psychology students with an accurate and authoritative reference for psychotropic drugs that are commonly available for clinical prescription in North America. The reference is particularly directed for use by psychologists and psychology students who already have, or are currently developing, their professional expertise and responsibilities in the prescription and management of psychotropic pharmacotherapy as an adjunct to their psychotherapy. The Reference lists detailed drug monographs for over 100 different prescription psychotropic drugs available in North America. Thus, this reference is the most comprehensive psychotropic drug reference for clinical psychologists currently available. Each psychotropic monograph is clearly and concisely written to only reflect essential and important data that are commonly required by prescribing psychologists. Whenever available and appropriate, each monograph includes phonetic pronunciation, up to five common trade or brand names, pharmacologic or therapeutic classification and subclassification, United States Drug Enforcement Agency (USDEA) schedule designation for abuse potential, recommended dosages for adults, children and the elderly, helpful and important notes regarding methods of administration, relative contraindications, clinically significant drug interactions and more. It is hoped that by using the information presented in is book prescribing psychologists and psychology students will be better able to provide their patients with the maximum benefits of adjunctive pharmacotherapy with a minimum of adverse and toxic effects.

Author : Hugh Lionel Freeman
Publisher : Unknown
Page : 78 pages
File Size : 51,8 Mb
Release : 1991
Category : Antidepressants
ISBN : UOM:39015024938196

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The Uses of Fluoxetine in Clinical Practice by Hugh Lionel Freeman Pdf

Author : Carl Elliott,Tod Chambers
Publisher : UNC Press Books
Page : 226 pages
File Size : 54,6 Mb
Release : 2004
Category : Medical
ISBN : 0807855510

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Prozac as a Way of Life by Carl Elliott,Tod Chambers Pdf

In this collection of eleven essays, leading doctors and bioethicists discuss the pros and cons of Prozac and America's culture of self-enhancement.

Author : Roni Shiloh,Rafael Stryjer,Abraham Weizman,David J. Nutt
Publisher : CRC Press
Page : 288 pages
File Size : 46,8 Mb
Release : 2006-01-13
Category : Medical
ISBN : 9781435626232

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Atlas of Psychiatric Pharmacotherapy by Roni Shiloh,Rafael Stryjer,Abraham Weizman,David J. Nutt Pdf

The second edition of this exceptional book provides a comprehensive understanding of the mechanisms of action involved in psychiatric pharmacotherapy. Using imaginative colourful double-page spreads, this exceptional book presents state-of-the-art information on all the basic principles of psychiatric pharmacotherapy, abused substances, drug inter

Author : Joris C. Verster,S. R. Pandi-Perumal,Jan G. Ramaekers,Johan J. de Gier
Publisher : Springer Science & Business Media
Page : 564 pages
File Size : 53,9 Mb
Release : 2009-08-29
Category : Medical
ISBN : 9783764399238

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Drugs, Driving and Traffic Safety by Joris C. Verster,S. R. Pandi-Perumal,Jan G. Ramaekers,Johan J. de Gier Pdf

Drugs, Driving and Traffic Safety gives a comprehensive overview of the effects of different medical conditions like neurological disorders, anxiety and depression and their pharmaceutical treatment on driving ability. In addition, the effects of alcohol and drugs of abuse are discussed. Leading experts present the different methodologies to examine effects of drugs on driving, and summarize the recent scientific evidence including epidemiological studies, roadside surveys, laboratory tests, driving simulators, and the standardized driving test. The volume includes guidelines of the International Council on Alcohol, Drugs and Traffic Safety (ICADTS) and the ICADTS Drugs List 2007. Drugs, Driving and Traffic Safety is written for physicians, psychiatrists and pharmacists who want to inform their patients who use psychoactive drugs.

Author : Anonim
Publisher : Unknown
Page : 1476 pages
File Size : 40,9 Mb
Release : 1991
Category : Medicine
ISBN : OSU:32436010178778

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Cumulated Index Medicus by Anonim Pdf