Fractal Binding And Dissociation Kinetics For Different Biosensor Applications

Author : Ajit Sadana
Publisher : Elsevier
Page : 650 pages
File Size : 51,6 Mb
Release : 2005-07-06
Category : Technology & Engineering
ISBN : 0080458912

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Fractal Binding and Dissociation Kinetics for Different Biosensor Applications by Ajit Sadana Pdf

Biosensors are portable and convenient devices that permit the rapid and reliable analysis of substances. They are increasingly used in healthcare, drug design, environmental monitoring and the detection of biological, chemical, and toxic agents. Fractal Binding and Dissociation Kinetics for Different Biosensor Applications focuses on two areas of expanding biosensor development that include (a) the detection of biological and chemical pathogens in the atmosphere, and (b) biomedical applications, especially in healthcare. The author provides numerous examples of practical uses, particularly biomedical applications and the detection of biological or chemical pathogens. This book also contains valuable information dedicated to the economics of biosensors. After reading this book, the reader will gain invaluable insight into how biosensors work and how they may be used more effectively. * No other book provides a detailed kinetic analysis of the binding and dissociation reactions occurring on the biosensor surfaces * Packed with examples of practical uses of biosensors * Includes chapters dedicated to the economics of biosensors

Author : Ajit Sadana
Publisher : Elsevier
Page : 384 pages
File Size : 46,5 Mb
Release : 2006-08-08
Category : Science
ISBN : 008046369X

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Binding and Dissociation Kinetics for Different Biosensor Applications Using Fractals by Ajit Sadana Pdf

The application of biosensors is expanding in different areas. These are portable and convenient devices that permit the rapid, accurate, and reliable detection of analytes of interest present either in the atmosphere or in aqueous or in liquid phases. The detection of glucose levels in blood for the effective management of diabetes is one. Though different biosensors have been designed for an increasing number of applications, the kinetics of binding (and dissociation) of analytes by the receptors on the biosensor surfaces has not been given enough attention in the open literature. This is a very important area of investigation since it significantly impacts biosensor performance parameters such as stability, sensitivity, selectivity, response time, regenerability, etc. Binding and Dissociation Kinetics for Different Biosensor Applications Using Fractals addresses this critical need besides helping to correct or demonstrate the need to modify the present software available with commercial biosensors that determines the kinetics of analyte-receptor reactions on biosensor surfaces. * first book to provide detailed kinetic analysis of the binding and dissociation reactions that are occuring on the biosensor surface * addresses the area of analyte-receptor binding and dissociation kinetics occurring on biosensor surfaces * provides physical insights into reactions occuring on biosensor surfaces

Author : Ajit Sadana,Neeti Sadana
Publisher : Elsevier
Page : 372 pages
File Size : 51,8 Mb
Release : 2007-12-20
Category : Science
ISBN : 0080555012

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Fractal Analysis of the Binding and Dissociation Kinetics for Different Analytes on Biosensor Surfaces by Ajit Sadana,Neeti Sadana Pdf

Biosensors are finding increasing applications in different areas. Over the last few years the areas where biosensors may be used effectively has increased dramatically. This book like the previous four books on analyte-receptor binding and dissociation kinetics by this author addresses the often neglected area. The kinetics of binding and dissociation in solution to appropriate receptors immobilized on biosensor surfaces occurs under diffusional limitations on structured surfaces. The receptors immobilized on the biosensor surface contribute to the degree of heterogeneity on the sensor chip surface. The fractal analysis examples presented throughout the book provide a convenient means to make quantitative the degree of heterogeneity present on the sensor surface, and relates it to the binding and dissociation rate coefficients. The fractal dimension is a quantitative measure of the degree of heterogeneity present on the biosensor surface. The book emphasizes medially-oriented examples. The detection of disease-related analytes is also emphasized. The intent being that if intractable and insidious diseases are detected earlier, they will be controlled better, eventually leading to a better prognosis. Chapter 3 is a new chapter that emphasizes enhancing the relevant biosensor performance parameters such as sensitivity, stability, selectivity, response time, etc. As usual, as done in previous books by this author, the last chapter provides an update of the economics involved in biosensors, and the difficulties encounters in starting-up a biosensor company. - Modelling of binding and dissociation kinetics of analyte-receptor reactions on biosensor surfaces: provides physical insights into these reactions occurring on biosensor surfaces. Very few researchers even attempt to analyze the kinetics of these types of reactions. - Fractal analysis used to model the binding and dissociation kinetics: original and unique approach. - Economic analysis provided in the last chapter: helps balance the book; besides providing much-needed information not available in the open literature. - Emphasis on improving biosensor performance parameters: helps make biosensors better. - Empahsis on medically-related analytes: helps in prognosis of diseases.

Author : Ajit Sadana
Publisher : Elsevier
Page : 426 pages
File Size : 54,9 Mb
Release : 2003-12-17
Category : Mathematics
ISBN : 0444515127

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Biosensors: Kinetics of Binding and Dissociation Using Fractals by Ajit Sadana Pdf

Effect of Reynolds number on fractal binding kinetics on a surface-based biosensor -- DNA fractal binding and dissociation kinetics -- Fractal analysis of binding and dissociation interactions of estrogen receptors to ligands on biosensor surfaces -- A fractal analysis of analyte-estrogen receptor binding and dissociation kinetics using biosensors : environmental effects -- A fractal analysis of analyte-estrogen receptor binding and dissociation kinetics using biosensors : biomedical effects -- Fractal analysis of binding interactions of nuclear estrogen receptors occurring on biosensor surfaces -- A kinetic study of analyte-receptor binding and dissociation for biosensor applications : a fractal analysis for cholera toxin and peptide-protein interactions / -- The temporal nature of the binding and dissociation rate coefficients and the affinity values for biosensor kinetics -- Fractal analysis of analyte-receptor binding and dissociation, and dissociation alone for biosensor applicati ...

Author : Ajit Sadana,Neeti Sadana,Richa Sadana
Publisher : Elsevier
Page : 337 pages
File Size : 44,9 Mb
Release : 2018-07-31
Category : Technology & Engineering
ISBN : 9780444638823

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A Fractal Analysis of Chemical Kinetics with Applications to Biological and Biosensor Interfaces by Ajit Sadana,Neeti Sadana,Richa Sadana Pdf

A Fractal Analysis of Chemical Kinetics with Applications to Biological and Biosensor Interfaces analyzes the kinetics of binding and dissociation of different analytes by different biosensor techniques, demonstrating and then comparing each. Emphasis is placed on newer instrumentation techniques, such as SPRi (surface plasmon resonance imaging), and classical techniques, such as SPR (surface plasmon resonance), and finally, DNA biosensors and nanobiosensors. In addition, a final capstone chapter includes biosensor economics. These topics are all covered in one comprehensive book in a way that cannot be found elsewhere. Analyzes the kinetics of binding on biosensor surfaces Presents and compares different biosensor techniques Provides insights into the binding and dissociation mechanisms of analytes on biosensor surfaces Links the heterogeneity of biosensor surfaces to dissociation rate coefficients

Author : Ajit Sadana,Neeti Sadana
Publisher : Elsevier
Page : 536 pages
File Size : 46,6 Mb
Release : 2010-08-26
Category : Science
ISBN : 0080932851

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Handbook of Biosensors and Biosensor Kinetics by Ajit Sadana,Neeti Sadana Pdf

Biosensors are essential to an ever-expanding range of applications, including healthcare; drug design; detection of biological, chemical, and toxic agents; environmental monitoring; biotechnology; aviation; physics; oceanography; and the protection of civilian and engineering infrastructures. This book, like the previous five books on biosensors by this author (and one by the co-author), addresses the neglected areas of analyte-receptor binding and dissociation kinetics occurring on biosensor surfaces. Topics are covered in a comprehensive fashion, with homogeneous presentation for the benefit of the reader. The contributors address the economic aspects of biosensors and incorporate coverage of biosensor fabrication and nanobiosensors, among other topics. The comments, comparison, and discussion presented provides a better perspective of where the field of biosensors is heading. Serves as a comprehensive resource on biosensor analysis Examines timely topics such as biosensor fabrication and nanobiosensors Covers economic aspects and medical applications (e.g., the role of analytes in controlling diabetes)

Author : Ajit Sadana,Neeti Sadana
Publisher : Newnes
Page : 703 pages
File Size : 54,8 Mb
Release : 2014-12-08
Category : Medical
ISBN : 9780444537959

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Biomarkers and Biosensors by Ajit Sadana,Neeti Sadana Pdf

Biomarkers and Biosensors offers thorough coverage of biomarker/biosensor interaction, current research trends, and future developments in applications of drug discovery. This book is useful to researchers in this field as well as clinicians interested in new developments in early detection and diagnosis of disease or the mode of operation of biomarkers. Biomarkers and Biosensors also emphasizes kinetics, and clearly delineates how this influences the biomarker market. Offers thorough coverage of the kinetics of biomarker interaction with the biosensor surface Provides evidence-based approach to evaluate effectiveness Provides pharmaceutical chemists the possibilities and methodology in assessing the effectiveness of new drugs Provides the information needed for the selection of the best biomarker for a specific application

Author : Ajit Sadana
Publisher : Academic Press
Page : 419 pages
File Size : 54,5 Mb
Release : 2001-10-04
Category : Science
ISBN : 9780080523637

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Engineering Biosensors by Ajit Sadana Pdf

Biosensors are becoming increasingly important bioanalytical tools in the pharmaceutical, biotechnology, food, and other consumer oriented industries. The technology, though well developed in Europe, is slowly developing and has begun to generate interest in the United States only over the past couple of years. Research is now being directed toward the development of biosensors that are versatile, economical, and simple to use.Engineering Biosensors is a comprehensive introduction to biosensors that includes numerous illustrations to further explain the main concepts and practical examples from existing literature. It describes what biosensors are, where they are used, and how their performance is affected by existing surface characteristics.A better understanding of biosensors, as provided by this book, will greatly assist in the design of new as well as the improvement of existing biosensors. Readers are also provided with invaluable and hard-to-find data on the economics of the biosensor market to assist them in better understanding the market and where it is heading.

Author : Jata Shankar,Pradeep Verma,Maulin P. Shah
Publisher : CRC Press
Page : 357 pages
File Size : 47,9 Mb
Release : 2024-06-06
Category : Technology & Engineering
ISBN : 9781040025758

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Microbial Approaches for Sustainable Green Technologies by Jata Shankar,Pradeep Verma,Maulin P. Shah Pdf

Microbial systems have a strong potential to develop green and sustainable technologies, including sources of renewable energy, alternative fuels, and biosynthetic materials for sustainable applications. Advances in these technologies are evolving to meet growing demand and industries are adapting to green technologies such as solar panels, bioethanol, hydroponics, and more. With the aid of sophisticated technology and integration strategies, these industries are moving toward being more environmentally friendly and sustainable. This book serves as a guide to the newest technologies that will enable the implementation of microbial technologies in fostering an eco-friendly industrial and environmental landscape, which will have widely positive impacts for generations to come. Provides recent insights on diverse technologies involved in green technologies Explains the application of microbes via fungi to remediate pollutants and examines the latest treatment technologies in bioleaching and electronic waste treatment Provides updated information on bioenergy and flexible fungal materials as alternatives to plastics Discusses the application of IOT and communication electronics in the development of green technologies

Author : B. Xu,H.Y. Li
Publisher : Trans Tech Publications Ltd
Page : 560 pages
File Size : 45,6 Mb
Release : 2012-03-27
Category : Technology & Engineering
ISBN : 9783038138136

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Functional Materials and Nanotechnology by B. Xu,H.Y. Li Pdf

Volume is indexed by Thomson Reuters CPCI-S (WoS). These are the proceedings of the International Conference on Functional Materials and Nanotechnology (FMN2012), held on the 19 and 20th May, 2012, in Zhengzhou, P.R. China. They focus on Functional Materials and Nanotechnology. The peer-reviewed papers are divided into Chapter 1: Advanced Materials Engineering and Nanotechnology; Chapter 2: Nanotechnology, Mechanics and Materials Science; Chapter 3: Materials Applications, Green Chemistry and Mining Engineering; Chapter 4: Materials, Biotechnology, Manufacturing Engineering and Environment.

Author : Poonam Mishra,Partha Pratim Sahu
Publisher : CRC Press
Page : 274 pages
File Size : 51,8 Mb
Release : 2022-04-25
Category : Science
ISBN : 9780429522062

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Biosensors in Food Safety and Quality by Poonam Mishra,Partha Pratim Sahu Pdf

Biosensors in food safety and quality have become indispensable in today’s world due to the requirement of food safety and security for human health and nutrition. This book covers various types of sensors and biosensors that can be used for food safety and food quality monitoring, but these are not limited to conventional sensors, such as temperature sensors, optical sensors, electrochemical sensors, calorimetric sensors, and pH sensors. The chapters are framed in a way that readers can experience the novel fabrication procedures of some advanced sensors, including lab-on-a-chip biosensors, IoT-based sensors, microcontroller-based sensors, and so on, particularly for fruits and vegetables, fermented products, plantation products, dairy-based products, heavy metal analysis in water, meat, fish, etc. Its simplistic presentation and pedagogical writing provide the necessary thrust and adequate information for beginners, scientists, and researchers. The book offers comprehensive coverage of the most essential topics, which include the following: Fundamentals of biosensors Overview of food safety and quality analysis Major toxicants of food and water Fabrication techniques of biosensors applicable for different segments of the food industry This book serves as a reference for scientific investigators who work on the assurance of food safety and security using biosensing principles as well as researchers developing biosensors for food analysis. It may also be used as a textbook for graduate-level courses in bioelectronics.

Author : National Research Council,Division on Engineering and Physical Sciences,Board on Manufacturing and Engineering Design,Committee on Materials and Manufacturing Processes for Advanced Sensors
Publisher : National Academies Press
Page : 209 pages
File Size : 49,9 Mb
Release : 2005-12-11
Category : Political Science
ISBN : 9780309095761

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Sensor Systems for Biological Agent Attacks by National Research Council,Division on Engineering and Physical Sciences,Board on Manufacturing and Engineering Design,Committee on Materials and Manufacturing Processes for Advanced Sensors Pdf

Over the last ten years, there has been growing concern about potential biological attacks on the nation's population and its military facilities. It is now possible to detect such attacks quickly enough to permit treatment of potential victims prior to the onset of symptoms. The capability to "detect to warn", that is in time to take action to minimize human exposure, however, is still lacking. To help achieve such a capability, the Defense Threat Reduction Agency (DTRA) asked the National Research Council (NRC) to assess the development path for "detect to warn" sensors systems. This report presents the results of this assessment including analysis of scenarios for protecting facilities, sensor requirements, and detection technologies and systems. Findings and recommendations are provided for the most probable path to achieve a detect-to-warn capability and potential technological breakthroughs that could accelerate its attainment.

Author : James A. Schwarz,Cristian I. Contescu,Karol Putyera
Publisher : CRC Press
Page : 1006 pages
File Size : 53,7 Mb
Release : 2004
Category : Science
ISBN : 0824750489

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Dekker Encyclopedia of Nanoscience and Nanotechnology by James A. Schwarz,Cristian I. Contescu,Karol Putyera Pdf

Author : Munishwar N. Gupta
Publisher : Birkhäuser
Page : 234 pages
File Size : 47,7 Mb
Release : 2013-12-01
Category : Science
ISBN : 9783034881272

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Methods for Affinity-Based Separations of Enzymes and Proteins by Munishwar N. Gupta Pdf

One major concern of biotechnology is either using enzymes or producing them. Enzyme/protein production is therefore an important starting point for biotechnology. Bioseparation or Downstream Processing constitutes about 40-90% of the total production cost. Driven by economics, highly selective technologies applicable to large-scale processing have emerged during the last decade. These technologies are slowly diffusing to enzymologists who are working on a smaller scale, looking for fast and efficient purification protocols. The affinity-based techniques (including precipitation, two-phase extractions, expanded bed chromatography, perfusion chromatography and monoliths) described in this volume provide current and new cutting-edge methods. Consequently, the book is of main interest to researchers in biochemistry, biochemical engineering and biotechnology, working either in academic or industrial sectors.

Author : Mizutani Tadashi
Publisher : BoD – Books on Demand
Page : 644 pages
File Size : 46,7 Mb
Release : 2011-01-14
Category : Science
ISBN : 9789533079806

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Application of Thermodynamics to Biological and Materials Science by Mizutani Tadashi Pdf

Progress of thermodynamics has been stimulated by the findings of a variety of fields of science and technology. The principles of thermodynamics are so general that the application is widespread to such fields as solid state physics, chemistry, biology, astronomical science, materials science, and chemical engineering. The contents of this book should be of help to many scientists and engineers.