From Breakthrough To Blockbuster

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From Breakthrough to Blockbuster

Author : Donald L. Drakeman,Lisa N. Drakeman,Nektarios Oraiopoulos
Publisher : Oxford University Press
Page : 241 pages
File Size : 55,6 Mb
Release : 2022
Category : Biotechnology industries
ISBN : 9780195084009

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From Breakthrough to Blockbuster by Donald L. Drakeman,Lisa N. Drakeman,Nektarios Oraiopoulos Pdf

"Beginning in the 1970s, several scientific breakthroughs promised to transform the creation of new medicines. As investors sought to capitalize on these Nobel Prize-winning discoveries, the biotech industry grew to thousands of small companies around the world. Each sought to emulate what the major pharmaceutical companies had been doing for a century or more, but without the advantages of scale, scope, experience, and massive resources. How could a large collection of small companies, most with fewer than 50 employees, compete in one of the world's most breathtakingly expensive and highly regulated industries? This book shows how biotech companies have met the challenge by creating nearly 40% more of the most important treatments for unmet medical needs. Moreover, they have done so with much lower overall costs. The book focuses on both the companies themselves and the broader biotech ecosystem that supports them. Its portrait of the crucial roles played by academic research, venture capital, contract research organizations, the capital markets, and pharmaceutical companies shows how a supportive environment enabled the entrepreneurial biotech industry to create novel medicines with unprecedented efficiency. In doing so, it also offers insights for any industry seeking to innovate in uncertain and ambiguous conditions. Looking to the future, it concludes that biomedical research will continue to be most effective in the hands of a large group of small companies as long as national healthcare policies allow the rest of the ecosystem to continue to thrive"--

From Breakthrough to Blockbuster

Author : Donald L. Drakeman,Lisa N. Drakeman,Nektarios Oraiopoulos
Publisher : Oxford University Press
Page : 241 pages
File Size : 51,5 Mb
Release : 2022-02-14
Category : Science
ISBN : 9780197626306

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From Breakthrough to Blockbuster by Donald L. Drakeman,Lisa N. Drakeman,Nektarios Oraiopoulos Pdf

Financial Times Business Top Title March 2022 How could a large collection of small companies, most with fewer than 50 employees, rise to compete with Big Pharma, one of the world's most breathtakingly expensive and highly regulated industries? Beginning in the 1970s, several scientific breakthroughs promised to transform the creation of new medicines. As investors sought to capitalize on these Nobel Prize-winning discoveries, the biotech industry grew to thousands of small companies around the world. Each sought to emulate what the major pharmaceutical companies had been doing for a century or more, but without the advantages of scale, scope, experience, and massive resources. Biotech companies have met the challenge by creating nearly 40% more of the most important treatments for previously unmet medical needs. Moreover, they have done so with much lower overall costs. From Breakthrough to Blockbuster: The Business of Biotechnology focuses on both the companies themselves and the broader biotech ecosystem that supports them. It paints a portrait of the crucial roles played by academic research, venture capital, contract research organizations, the capital markets, and pharmaceutical companies, demonstrating how a supportive environment enabled the entrepreneurial biotech industry to create novel medicines with unprecedented efficiency. In doing so, it also offers insights for any industry seeking to innovate in uncertain and ambiguous conditions.

Science Lessons

Author : Gordon M. Binder,Philip Bashe
Publisher : Harvard Business Review Press
Page : 326 pages
File Size : 46,5 Mb
Release : 2008
Category : Biography & Autobiography
ISBN : UOM:39015079165190

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Science Lessons by Gordon M. Binder,Philip Bashe Pdf

Under Gordon Binder's leadership, Amgen became the world's largest and most successful biotech company in the world. This text describes what it really takes to manage risk, financing, creative employees, and intellectual property on the international stage.

Science Business

Author : Gary P. Pisano
Publisher : Harvard Business Press
Page : 278 pages
File Size : 53,9 Mb
Release : 2006
Category : Business & Economics
ISBN : 1591398401

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Science Business by Gary P. Pisano Pdf

Why has the biotechnology industry failed to perform up to expectations? This book attempts to answer this question by providing a critique of the industry. It reveals the causes of biotech's problems and offers an analysis on how the industry works. It also provides prescriptions for companies, seeking ways to improve the industry's performance.

Liberal Education and Citizenship in a Free Society

Author : Justin Buckley Dyer,Constantine Christos Vassiliou
Publisher : University of Missouri Press
Page : 462 pages
File Size : 49,9 Mb
Release : 2023-07-24
Category : Political Science
ISBN : 9780826274885

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Liberal Education and Citizenship in a Free Society by Justin Buckley Dyer,Constantine Christos Vassiliou Pdf

The liberal arts university has been in decline since well before the virtualization of campus life, increasingly inviting public skepticism about its viability as an institution of personal, civic, and professional growth. New technologies that might have brought people together have instead frustrated the university’s capacity to foster thoughtful citizenship among tomorrow’s leaders and exacerbated socioeconomic inequalities that are poisoning America’s civic culture. With Liberal Education and Citizenship in a Free Society, a collection of 19 original essays, editors Justin Dyer and Constantine Vassiliou present the work of a diverse group of scholars to assess the value of a liberal arts education in the face of market, technological, cultural, and political forces shaping higher learning today.

Biotechnology Entrepreneurship

Author : Craig Shimasaki
Publisher : Academic Press
Page : 489 pages
File Size : 45,8 Mb
Release : 2014-04-08
Category : Medical
ISBN : 9780124047471

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Biotechnology Entrepreneurship by Craig Shimasaki Pdf

As an authoritative guide to biotechnology enterprise and entrepreneurship, Biotechnology Entrepreneurship and Management supports the international community in training the biotechnology leaders of tomorrow. Outlining fundamental concepts vital to graduate students and practitioners entering the biotech industry in management or in any entrepreneurial capacity, Biotechnology Entrepreneurship and Management provides tested strategies and hard-won lessons from a leading board of educators and practitioners. It provides a ‘how-to’ for individuals training at any level for the biotech industry, from macro to micro. Coverage ranges from the initial challenge of translating a technology idea into a working business case, through securing angel investment, and in managing all aspects of the result: business valuation, business development, partnering, biological manufacturing, FDA approvals and regulatory requirements. An engaging and user-friendly style is complemented by diverse diagrams, graphics and business flow charts with decision trees to support effective management and decision making. Provides tested strategies and lessons in an engaging and user-friendly style supplemented by tailored pedagogy, training tips and overview sidebars Case studies are interspersed throughout each chapter to support key concepts and best practices. Enhanced by use of numerous detailed graphics, tables and flow charts

Can't Slow Down

Author : Michaelangelo Matos
Publisher : Hachette Books
Page : 480 pages
File Size : 43,5 Mb
Release : 2020-12-08
Category : Music
ISBN : 9780306903359

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Can't Slow Down by Michaelangelo Matos Pdf

A Rolling Stone-Kirkus Best Music Book of 2020 The definitive account of pop music in the mid-eighties, from Prince and Madonna to the underground hip-hop, indie rock, and club scenes Everybody knows the hits of 1984 - pop music's greatest year. From "Thriller" to "Purple Rain," "Hello" to "Against All Odds," "What's Love Got to Do with It" to "Wake Me Up Before You Go-Go," these iconic songs continue to dominate advertising, karaoke nights, and the soundtracks for film classics (Boogie Nights) and TV hits (Stranger Things). But the story of that thrilling, turbulent time, an era when Top 40 radio was both the leading edge of popular culture and a moral battleground, has never been told with the full detail it deserves - until now. Can't Slow Down is the definitive portrait of the exploding world of mid-eighties pop and the time it defined, from Cold War anxiety to the home-computer revolution. Big acts like Michael Jackson (Thriller), Prince (Purple Rain), Madonna (Like a Virgin), Bruce Springsteen (Born in the U.S.A.), and George Michael (Wham!'s Make It Big) rubbed shoulders with the stars of the fermenting scenes of hip-hop, indie rock, and club music. Rigorously researched, mapping the entire terrain of American pop, with crucial side trips to the UK and Jamaica, from the biz to the stars to the upstarts and beyond, Can't Slow Down is a vivid journey to the very moment when pop was remaking itself, and the culture at large - one hit at a time.

From Alchemy To Ipo

Author : Cynthia Robbins-roth
Publisher : Perseus Books
Page : 280 pages
File Size : 45,5 Mb
Release : 2000-05-18
Category : Business & Economics
ISBN : STANFORD:36105028488026

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From Alchemy To Ipo by Cynthia Robbins-roth Pdf

A fascinating glimpse inside the life-and-death business of biotechnology.

Understanding Pharma

Author : John J. Campbell
Publisher : Pharmaceutical Press
Page : 311 pages
File Size : 54,7 Mb
Release : 2008-01-01
Category : Pharmaceutical industry
ISBN : 0976309637

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Understanding Pharma by John J. Campbell Pdf

Blockbuster Drugs

Author : Jie Jack Li
Publisher : Oxford University Press
Page : 238 pages
File Size : 52,9 Mb
Release : 2014
Category : Business & Economics
ISBN : 9780199737680

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Blockbuster Drugs by Jie Jack Li Pdf

"This book uses the cases of several landmark drugs to discuss the history of the pharmaceutical industry, and discusses what could be next"--Provided by publisher.

Breakthrough

Author : James O'Keefe
Publisher : Simon and Schuster
Page : 352 pages
File Size : 48,9 Mb
Release : 2013-06-18
Category : Language Arts & Disciplines
ISBN : 9781476706177

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Breakthrough by James O'Keefe Pdf

In this hard-hitting look at the way media and government conspire to protect the status quo, a controversial ambush journalist shows readers what happens when a young citizen journalist challenges some of America's most powerful and protected organizations.

Hedy's Folly

Author : Richard Rhodes
Publisher : Vintage
Page : 298 pages
File Size : 53,5 Mb
Release : 2012-08-07
Category : Biography & Autobiography
ISBN : 9780307742957

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Hedy's Folly by Richard Rhodes Pdf

Pulitzer Prize-winning author Richard Rhodes delivers a remarkable story of science history: how a ravishing film star and an avant-garde composer invented spread-spectrum radio, the technology that made wireless phones, GPS systems, and many other devices possible. Beginning at a Hollywood dinner table, Hedy's Folly tells a wild story of innovation that culminates in U.S. patent number 2,292,387 for a "secret communication system." Along the way Rhodes weaves together Hollywood’s golden era, the history of Vienna, 1920s Paris, weapons design, music, a tutorial on patent law and a brief treatise on transmission technology. Narrated with the rigor and charisma we've come to expect of Rhodes, it is a remarkable narrative adventure about spread-spectrum radio's genesis and unlikely amateur inventors collaborating to change the world.

Genentech

Author : Sally Smith Hughes
Publisher : University of Chicago Press
Page : 231 pages
File Size : 46,9 Mb
Release : 2011-09-21
Category : Business & Economics
ISBN : 9780226359205

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Genentech by Sally Smith Hughes Pdf

In the fall of 1980, Genentech, Inc., a little-known California genetic engineering company, became the overnight darling of Wall Street, raising over $38 million in its initial public stock offering. Lacking marketed products or substantial profit, the firm nonetheless saw its share price escalate from $35 to $89 in the first few minutes of trading, at that point the largest gain in stock market history. Coming at a time of economic recession and declining technological competitiveness in the United States, the event provoked banner headlines and ignited a period of speculative frenzy over biotechnology as a revolutionary means for creating new and better kinds of pharmaceuticals, untold profit, and a possible solution to national economic malaise. Drawing from an unparalleled collection of interviews with early biotech players, Sally Smith Hughes offers the first book-length history of this pioneering company, depicting Genentech’s improbable creation, precarious youth, and ascent to immense prosperity. Hughes provides intimate portraits of the people significant to Genentech’s science and business, including cofounders Herbert Boyer and Robert Swanson, and in doing so sheds new light on how personality affects the growth of science. By placing Genentech’s founders, followers, opponents, victims, and beneficiaries in context, Hughes also demonstrates how science interacts with commercial and legal interests and university research, and with government regulation, venture capital, and commercial profits. Integrating the scientific, the corporate, the contextual, and the personal, Genentech tells the story of biotechnology as it is not often told, as a risky and improbable entrepreneurial venture that had to overcome a number of powerful forces working against it.

Instant Appeal

Author : Vicki Kunkel
Publisher : Unknown
Page : 0 pages
File Size : 45,9 Mb
Release : 2022-06-13
Category : Business & Economics
ISBN : 1400232627

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Instant Appeal by Vicki Kunkel Pdf

What do some of the biggest business successes in the world have in common? The secret to who and what has staying power lies in deeply ingrained biological and anthropological codes we all subconsciously share.?This book teaches you about the instant appeal of evolutionary psychology as it applies to business today. Instant Appeal reveals the often surprising yet proven reasons behind why we vote for certain people, listen to the same songs repeatedly, and favor one brand over another. Communications consultant expert Vicki Kunkel illuminates the human universals that cause positive and negative chemical reactions in our brains, and shows how anyone can use them to advance their career, cause, company, or product. In Instant Appeal, Kunkel reveals the secrets of the "stickiness" phenomenon such as: observations about human behavior and hypotheses on how to market people, ideas, and things how to use primal persuaders to make yourself stand out in a competitive marketplace and enhance your success the science, insights, and statistics behind what it takes to create instant appeal and make the factors of attraction work for you and your business The key is responsibility and the secrets of persuasion can be appealing and effective. When used in a reputable manner, the eight primal factors within Instant Appeal can help you achieve blockbuster success without abusing the power they contain.

Blockbuster History in the New Russia

Author : Stephen M. Norris
Publisher : Indiana University Press
Page : 407 pages
File Size : 51,8 Mb
Release : 2012-10-19
Category : History
ISBN : 9780253006790

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Blockbuster History in the New Russia by Stephen M. Norris Pdf

Seeking to rebuild the Russian film industry after its post-Soviet collapse, directors and producers sparked a revival of nationalist and patriotic sentiment by applying Hollywood techniques to themes drawn from Russian history. Unsettled by the government's move toward market capitalism, Russians embraced these historical blockbusters, packing the American-style multiplexes that sprouted across the country. Stephen M. Norris examines the connections among cinema, politics, economics, history, and patriotism in the creation of "blockbuster history"—the adaptation of an American cinematic style to Russian historical epics.