Frontiers In Anti Infective Agents Volume 5

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Frontiers in Anti-Infective Agents: Volume 5

Parvesh Singh,Vipan Kumar ,Rajshekhar Karpoormath
Frontiers in Anti Infective Agents Volume 5 Book PDF

Author : Parvesh Singh,Vipan Kumar ,Rajshekhar Karpoormath
Publisher : Bentham Science Publishers
Page : 242 pages
File Size : 42,8 Mb
Release : 2021-09-14
Category : Medical
ISBN : 9789814998406

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Frontiers in Anti-Infective Agents: Volume 5 by Parvesh Singh,Vipan Kumar ,Rajshekhar Karpoormath Pdf

Anti-infective agents are a distinct class of pharmacologically important molecules that has served mankind in different capacities to combat life-threating pathologic conditions. They include antibacterial, antifungal, antiviral, antituberculosis, antimalarial and urinary anti-infective agents. However, evolutionary changes, adaptations and development of pathogenic microorganisms strains the therapeutic efficacy of these drugs thus limiting their clinical utility over the years. Frontiers in Anti-Infective Agents Volume 5 is a collection of notable research efforts, successful anti-infective drug development programmes and a comprehensive overview of the successes and failures of recent clinical trials in this domain. The volume covers interesting topics: 1) the treatment of acute wounds with the vikut® formula, 2) anti-infective treatment of ocular diseases and 3) sars-cov vaccine development and antimicrobial therapy for SARS symptoms. A chapter summarizing recent anti-infective approaches rounds up the contents of this volume. This volume is a timely reference for postgraduate scholars and researchers seeking updates in specific areas of anti-infective drug development. Allied healthcare professionals (clinical and public healthcare professionals) can also benefit from the information presented within.

Frontiers in Anti-Infective Agents: Volume 6

Parvesh Singh
Frontiers in Anti Infective Agents Volume 6 Book PDF

Author : Parvesh Singh
Publisher : Bentham Science Publishers
Page : 194 pages
File Size : 47,9 Mb
Release : 2021-11-17
Category : Medical
ISBN : 9789814998437

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Frontiers in Anti-Infective Agents: Volume 6 by Parvesh Singh Pdf

Anti-infective agents are a distinct class of pharmacologically important molecules that have served mankind in different capacities to combat life-threatening pathological conditions. They include antibacterial, antifungal, antiviral, antituberculosis, antimalarial, and urinary anti-infective agents. However, evolutionary changes, adaptations, and the development of new strains of pathogenic microorganisms have reduced the therapeutic efficacy of existing drugs, thus, limiting their clinical utility over the years. Frontiers in Anti-Infective Agents Volume 6 is a collection of notable research efforts, successful anti-infective drug development programs, and a comprehensive overview of successful and unsuccessful clinical trials conducted in this domain. This volume continues from the last one with interesting reviews on 1) “Reverse Vaccinology” for vaccination design using computational data to identify vaccine targets, 2) leptospirosis, 3) phage therapy for bacterial infections, 4) quorum sensing inhibitors from natural products, and 5) nitrogen and oxygen-based heterocyclic compounds that can act as anti-infective agents. The volume, therefore, covers a range of frontier topics on anti-infective research and development. This compilation is a timely reference for postgraduate scholars and researchers seeking updates in specific areas of anti-infective drug development. Allied healthcare professionals (clinical and public healthcare professionals) can also benefit from the information presented within.

Frontiers in Clinical Drug Research - Anti Infectives: Volume 5

Atta-ur-Rahman
Frontiers in Clinical Drug Research Anti Infectives Volume 5 Book PDF

Author : Atta-ur-Rahman
Publisher : Bentham Science Publishers
Page : 246 pages
File Size : 48,7 Mb
Release : 2019-06-11
Category : Science
ISBN : 9781681086385

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Frontiers in Clinical Drug Research - Anti Infectives: Volume 5 by Atta-ur-Rahman Pdf

Frontiers in Clinical Drug Research – Anti infectives is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the book series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents.Frontiers in Clinical Drug Research – Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology. The fifth volume of this series features six reviews: - Integrated Approaches for Marine Actinomycete Biodiscovery - Therapeutic Use of Commensal Microbes: Fecal/Gut Microbiota Transplantation - Alternative Approaches to Antimicrobials - Nanoantibiotics: Recent Developments and Future - Cranberry Juice and Other Functional Foods in Urinary Tract Infections in Women: A Review of Actual Evidence and Main Challenges - Targeting Magnesium Homeostasis as Potential Anti-Infective Strategy Against Mycobacteria

Frontiers in Anti-Infective Drug Discovery

Atta-ur-Rahman,Muhammad Iqbal Choudhary,George Perry
Frontiers in Anti Infective Drug Discovery Book PDF

Author : Atta-ur-Rahman,Muhammad Iqbal Choudhary,George Perry
Publisher : Unknown
Page : 128 pages
File Size : 50,8 Mb
Release : 2011-08-11
Category : Electronic
ISBN : 1608055833

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Frontiers in Anti-Infective Drug Discovery by Atta-ur-Rahman,Muhammad Iqbal Choudhary,George Perry Pdf

"Frontiers in Anti-Infective Drug Discovery" is an Ebook series devoted to publishing the latest and the most important advances in Anti-Infective drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and

Frontiers in Anti-Infective Drug Discovery: Volume 9

Atta-ur-Rahman, M. Iqbal Chaudhary
Frontiers in Anti Infective Drug Discovery Volume 9 Book PDF

Author : Atta-ur-Rahman, M. Iqbal Chaudhary
Publisher : Bentham Science Publishers
Page : 229 pages
File Size : 50,9 Mb
Release : 2021-05-24
Category : Medical
ISBN : 9781681088303

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Frontiers in Anti-Infective Drug Discovery: Volume 9 by Atta-ur-Rahman, M. Iqbal Chaudhary Pdf

This book series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. The scope of the book series covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field. The ninth volume of this series features 5 reviews that cover some aspects of clinical and pre-clinical antimicrobial drug development, with 2 chapters focusing on drugs to treat leishmaniasis and dengue fever, respectively. - Use of preclinical and early clinical data for accelerating antimicrobial drug development - Post-translational modifications: host defence mechanism, pathogenic weapon, and emerged target of anti-infective drugs - Scope and limitations on the potent antimicrobial activities of hydrazone derivatives - Current scenario of anti-leishmanial drugs and treatment - Dengue hemorrhagic fever: the potential repurposing drugs

Anti-infective Research and Development

Gloria Guillermina Guerrero Manriquez
Anti infective Research and Development Book PDF

Author : Gloria Guillermina Guerrero Manriquez
Publisher : Unknown
Page : 206 pages
File Size : 40,7 Mb
Release : 2020-10-23
Category : Electronic
ISBN : 9811469571

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Anti-infective Research and Development by Gloria Guillermina Guerrero Manriquez Pdf

This volume of Frontiers in Anti-Infective Agents provides updates on the most recent studies about anti-infective agents, their mechanism of action, the relevant molecular targets and their implication in the development of novel antibiotics that have properties similar to their corresponding compounds of natural origin. The initial chapter covers the mode of action of natural antimycobacterial compounds such as nordihydroguaiaretic acid, α-mangostin and allicin, as well as antimicrobial peptides and their role in the innate and adaptive immune response leading to the decrease of microbial resistance. This is followed by updates on tuberculosis treatment concerning the immunological role of cells (airway epithelial cells, macrophages, neutrophils and T cells) along with their products (chemokines, cytokines) and other processes such as autophagy that influence the outcome of the host immune response to the infection. Contributors have also reviewed the latest knowledge in the cellular and molecular mechanisms that trigger a protective, immune response and the identification of the molecular targets for vaccine development, all of which are a key priority to develop control measures against Babesia species like Babesia bovis and Babesia bigemina. Additionally, the neuro-endocrine and neuro-immune mechanisms behind host responses against stress and environmental stimuli during infections are also covered in separate chapters. The volume also provides updates related to Helicobacter pylori pathogenesis. The reviews presented in Anti-infective Research and Development provide timely updates for scholars and professionals associated with the field of antimicrobial research and development.

Frontiers in Anti-Infective Drug Discovery Volume

Atta-ur-Rahman; Iqbal Chaudhary,Atta -Ur-Rahman
Frontiers in Anti Infective Drug Discovery Volume Book PDF

Author : Atta-ur-Rahman; Iqbal Chaudhary,Atta -Ur-Rahman
Publisher : Bentham Science Publishers
Page : 229 pages
File Size : 51,6 Mb
Release : 2021-05-24
Category : Electronic
ISBN : 1681088312

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Frontiers in Anti-Infective Drug Discovery Volume by Atta-ur-Rahman; Iqbal Chaudhary,Atta -Ur-Rahman Pdf

This book series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. The scope of the book series covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field. The ninth volume of this series features 5 reviews that cover some aspects of clinical and pre-clinical antimicrobial drug development, with 2 chapters focusing on drugs to treat leishmaniasis and dengue fever, respectively. - Use of preclinical and early clinical data for accelerating antimicrobial drug development - Post-translational modifications: host defence mechanism, pathogenic weapon, and emerged target of anti-infective drugs - Scope and limitations on the potent antimicrobial activities of hydrazone derivatives - Current scenario of anti-leishmanial drugs and treatment - Dengue hemorrhagic fever: the potential repurposing drugs

Anti-infective Research and Development: Updates on Infection Mechanisms and Treatments

Gloria G. Guerrero Manriquez
Anti infective Research and Development Updates on Infection Mechanisms and Treatments Book PDF

Author : Gloria G. Guerrero Manriquez
Publisher : Bentham Science Publishers
Page : 206 pages
File Size : 44,6 Mb
Release : 2020-10-19
Category : Medical
ISBN : 9789811469565

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Anti-infective Research and Development: Updates on Infection Mechanisms and Treatments by Gloria G. Guerrero Manriquez Pdf

This volume of Frontiers in Anti-Infective Agents provides updates on the most recent studies about anti-infective agents, their mechanism of action, the relevant molecular targets and their implication in the development of novel antibiotics that have properties similar to their corresponding compounds of natural origin. The initial chapter covers the mode of action of natural antimycobacterial compounds such as nordihydroguaiaretic acid, α-mangostin and allicin, as well as antimicrobial peptides and their role in the innate and adaptive immune response leading to the decrease of microbial resistance. This is followed by updates on tuberculosis treatment concerning the immunological role of cells (airway epithelial cells, macrophages, neutrophils and T cells) along with their products (chemokines, cytokines) and other processes such as autophagy that influence the outcome of the host immune response to the infection. Contributors have also reviewed the latest knowledge in the cellular and molecular mechanisms that trigger a protective, immune response and the identification of the molecular targets for vaccine development, all of which are a key priority to develop control measures against Babesia species like Babesia bovis and Babesia bigemina. Additionally, the neuro-endocrine and neuro-immune mechanisms behind host responses against stress and environmental stimuli during infections are also covered in separate chapters. The volume also provides updates related to Helicobacter pylori pathogenesis. The reviews presented in Anti-infective Research and Development provide timely updates for scholars and professionals associated with the field of antimicrobial research and development.

Pregnancy and Anti-Infective Agents

Ricardo Ney Cobucci
Pregnancy and Anti Infective Agents Book PDF

Author : Ricardo Ney Cobucci
Publisher : Bentham Science Publishers
Page : 186 pages
File Size : 53,9 Mb
Release : 2020-11-19
Category : Medical
ISBN : 9789811479571

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Pregnancy and Anti-Infective Agents by Ricardo Ney Cobucci Pdf

This concise clinical reference facilitates health consultants and professionals for determining treatment options for some common prenatal and postpartum infections during pregnancy and the puerperium in patients. Key Features - Presents 9 organized, easy to read chapters on anti-infective agents for pregnant patients - Covers pharmacokinetics and pharmacodynamics of relevant anti-infective agents - Includes information on classification and safety of anti-infective agents - Includes treatment of urinary tract infections - Covers medications for sexually transmitted diseases, including a complete section dedicated to HIV medication - Provides information about vulvovaginal infections - Covers the treatment of toxoplasmosis in pregnancy - innovates with information about herbal remedies for infection for patients during pregnancy and breastfeeding Pregnancy and Anti-Infective Agents is therefore, a valuable handbook that enables quick consultation on safe antibiotics for the treatment of a variety of infections in pregnancy.

Current Perspectives on Anti-Infective Agents

K. Tamreihao,Saikat Mukherjee,Debananda S. Ningthoujam
Current Perspectives on Anti Infective Agents Book PDF

Author : K. Tamreihao,Saikat Mukherjee,Debananda S. Ningthoujam
Publisher : Bentham Science Publishers
Page : 278 pages
File Size : 55,6 Mb
Release : 2019-11-18
Category : Medical
ISBN : 9789811432729

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Current Perspectives on Anti-Infective Agents by K. Tamreihao,Saikat Mukherjee,Debananda S. Ningthoujam Pdf

The volume is a comprehensive documentation on major infectious diseases from tropical countries which pose a serious threat to global healthcare programs. These include diseases such as tuberculosis, AIDS, leishmaniasis (kala-azar), elephantiasis, malaria, leprosy, various fungal disorders and emergent viral diseases. Due to the widespread use of antibiotics, there is an emergence of drug-resistant pathogens in many regions. Hence, there is a need to search for novel, cost-effective bioactive compounds that demonstrate high efficacy and low toxicity in human cells from unexplored ecosystems to combat emerging drug-resistant pathogens. Chapters of this volume focus on the pathogenesis and etiology of each of the mentioned diseases, updated WHO reports wherever applicable, conventional drugs and their pharmacokinetics as well as new approaches to develop anti-infective agents. The authors also present a detailed report on ‘superbugs’ (multi-drug resistant pathogens) and new measures being taken up to eradicate them. Information about new antimicrobials (bioactive peptides and silk protein sericin) and the approaches taken by scientists and healthcare professionals for successful targeting of these molecules for human medicine. This volume is essential for general readers, healthcare professionals, researchers, and academicians actively involved in research on infectious diseases and anti-infective therapeutic drugs. [Series Introduction] Frontiers in Anti-Infective Agents is a book series that focuses on current and new antibiotics and vaccines. The series highlights the challenges faced by healthcare workers around the globe when facing epidemics caused by life-threatening pathogens along with the measures being taken to combat these challenges. The series is essential reading for all involved in infectious disease research including microbiologists, medical professionals, epidemiologists, and life science researchers.

21st Century Challenges in Antimicrobial Therapy and Stewardship

Islam M. Ghazi, Michael J. Cawley
21st Century Challenges in Antimicrobial Therapy and Stewardship Book PDF

Author : Islam M. Ghazi, Michael J. Cawley
Publisher : Bentham Science Publishers
Page : 493 pages
File Size : 43,8 Mb
Release : 2020-11-19
Category : Medical
ISBN : 9789811461811

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21st Century Challenges in Antimicrobial Therapy and Stewardship by Islam M. Ghazi, Michael J. Cawley Pdf

21st Century Challenges in Antimicrobial Therapy and Stewardship addresses selected topics that are of importance in the practice of infectious disease management. The text starts by illustrating the global landscape of antimicrobial drug resistance, which influences antimicrobial use and therapeutic decisions in the clinic. The contributors explain the reasons for the spread of antibiotic resistance, the pharmacology of antibiotics of different classes, innovative drug delivery methods which can improve the efficacy and safety of new drug candidates and achieve targeted drug delivery as well as drug resistance monitoring techniques and issues in the practice of antimicrobial stewardship and infection control. Key Features: - 14 organized chapters on several aspects of antimicrobial therapy and stewardship - Introductory knowledge on global antimicrobial trends - Coverage of molecular basis of antimicrobial resistance in gram positive, gram negative and fungal microbes - Focused coverage on new developments in antimicrobial drug development, drug delivery, formulation and diagnostic tools - Information on unmet needs of patients and clinicians, including the treatment of difficult infections - Comprehensive coverage of issues in antimicrobial stewardship 21st Century Challenges in Antimicrobial Therapy and Stewardship brings to readers – healthcare administrators, educators, pharmacists, clinicians and students, alike – the knowledge of the molecular basis of antimicrobial drug therapy, drug resistance in pathogens and current practices in antimicrobial stewardship programs. This knowledge, in turn, fosters an awareness among healthcare industry participants to collaborate in an interprofessional environment to combat multidrug resistance.

Disease Control Priorities, Third Edition (Volume 6)

King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha
Disease Control Priorities Third Edition Volume 6 Book PDF

Author : King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha
Publisher : World Bank Publications
Page : 506 pages
File Size : 40,5 Mb
Release : 2017-11-06
Category : Medical
ISBN : 9781464805257

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Disease Control Priorities, Third Edition (Volume 6) by King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha Pdf

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Frontiers in Clinical Drug Research: HIV

Atta-ur-Rahman
Frontiers in Clinical Drug Research HIV Book PDF

Author : Atta-ur-Rahman
Publisher : Bentham Science Publishers
Page : 348 pages
File Size : 52,9 Mb
Release : 2015-11-27
Category : Medical
ISBN : 9781681082011

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Frontiers in Clinical Drug Research: HIV by Atta-ur-Rahman Pdf

Frontiers in Clinical Drug Research – HIV is an eBook series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of acquired immune deficiency syndrome (AIDS) and other disorders associated with human immunodeficiency virus (HIV) infection. The scope of the eBook series covers a range of topics including the medicinal chemistry and pharmacology of natural and synthetic drugs employed in the treatment of AIDS (including HAART) and resulting complications, and the virology and immunological study of HIV and related viruses. Frontiers in Clinical Drug Research – HIV is a valuable resource for pharmaceutical scientists, clinicians and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in HIV/AIDS research. The second volume of this series features 5 chapters that cover a variety of topics including: - HIV-1 Integrase Inhibitors - HIV in vaginal mucosa - Long-Acting Antiretroviral Formulations -The world of people living with HIV/AIDS.

Drug Repositioning: Current Advances and Future Perspectives

Yuhei Nishimura,Hideaki Hara
Drug Repositioning Current Advances and Future Perspectives Book PDF

Author : Yuhei Nishimura,Hideaki Hara
Publisher : Frontiers Media SA
Page : 153 pages
File Size : 42,7 Mb
Release : 2019-01-11
Category : Electronic
ISBN : 9782889456963

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Drug Repositioning: Current Advances and Future Perspectives by Yuhei Nishimura,Hideaki Hara Pdf

Drug repositioning is the process of identifying new indications for existing drugs. At present, the conventional de novo drug discovery process requires an average of about 14 years and US$2.5 billion to approve and launch a drug. Drug repositioning can reduce the time and cost of this process because it takes advantage of drugs already in clinical use for other indications or drugs that have cleared phase I safety trials but have failed to show efficacy in the intended diseases. Historically, drug repositioning has been realized through serendipitous clinical observations or improved understanding of disease mechanisms. However, recent technological advances have enabled a more systematic approach to drug repositioning. This eBook collects 16 articles from 112 authors, providing readers with current advances and future perspectives of drug repositioning.

The Value of Information

Ramanan Laxminarayan,Molly K. Macauley
The Value of Information Book PDF

Author : Ramanan Laxminarayan,Molly K. Macauley
Publisher : Springer Science & Business Media
Page : 327 pages
File Size : 42,9 Mb
Release : 2012-08-14
Category : Business & Economics
ISBN : 9789400748392

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The Value of Information by Ramanan Laxminarayan,Molly K. Macauley Pdf

The book examines applications in two disparate fields linked by the importance of valuing information: public health and space. Researchers in the health field have developed some of the most innovative methodologies for valuing information, used to help determine, for example, the value of diagnostics in informing patient treatment decisions. In the field of space, recent applications of value-of-information methods are critical for informing decisions on investment in satellites that collect data about air quality, fresh water supplies, climate and other natural and environmental resources affecting global health and quality of life.