Fundamentals Of Bioinformatics And Computational Biology

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Fundamentals of Bioinformatics and Computational Biology

Author : Gautam B. Singh
Publisher : Springer
Page : 339 pages
File Size : 46,5 Mb
Release : 2014-09-24
Category : Technology & Engineering
ISBN : 9783319114033

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Fundamentals of Bioinformatics and Computational Biology by Gautam B. Singh Pdf

This book offers comprehensive coverage of all the core topics of bioinformatics, and includes practical examples completed using the MATLAB bioinformatics toolboxTM. It is primarily intended as a textbook for engineering and computer science students attending advanced undergraduate and graduate courses in bioinformatics and computational biology. The book develops bioinformatics concepts from the ground up, starting with an introductory chapter on molecular biology and genetics. This chapter will enable physical science students to fully understand and appreciate the ultimate goals of applying the principles of information technology to challenges in biological data management, sequence analysis, and systems biology. The first part of the book also includes a survey of existing biological databases, tools that have become essential in today’s biotechnology research. The second part of the book covers methodologies for retrieving biological information, including fundamental algorithms for sequence comparison, scoring, and determining evolutionary distance. The main focus of the third part is on modeling biological sequences and patterns as Markov chains. It presents key principles for analyzing and searching for sequences of significant motifs and biomarkers. The last part of the book, dedicated to systems biology, covers phylogenetic analysis and evolutionary tree computations, as well as gene expression analysis with microarrays. In brief, the book offers the ideal hands-on reference guide to the field of bioinformatics and computational biology.

Bioinformatics and Computational Biology

Author : Basant K. Tiwary
Publisher : Springer Nature
Page : 239 pages
File Size : 54,6 Mb
Release : 2021-11-23
Category : Medical
ISBN : 9789811642418

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Bioinformatics and Computational Biology by Basant K. Tiwary Pdf

This textbook introduces fundamental concepts of bioinformatics and computational biology to the students and researchers in biology, medicine, veterinary science, agriculture, and bioengineering . The respective chapters provide detailed information on biological databases, sequence alignment, molecular evolution, next-generation sequencing, systems biology, and statistical computing using R. The book also presents a case-based discussion on clinical, veterinary, agricultural bioinformatics, and computational bioengineering for application-based learning in the respective fields. Further, it offers readers guidance on reconstructing and analysing biological networks and highlights computational methods used in systems medicine and genome-wide association mapping of diseases. Given its scope, this textbook offers an essential introductory book on bioinformatics and computational biology for undergraduate and graduate students in the life sciences, botany, zoology, physiology, biotechnology, bioinformatics, and genomic science as well as systems biology, bioengineering and the agricultural, and veterinary sciences.

Fundamentals of Bioinformatics

Author : S. Harisha
Publisher : I. K. International Pvt Ltd
Page : 266 pages
File Size : 51,7 Mb
Release : 2013-12-30
Category : Bioinformatics
ISBN : 9788189866419

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Fundamentals of Bioinformatics by S. Harisha Pdf

Bioinformatics is an upcoming discipline of Life Sciences. It is an integration of computer science, and mathematical and statistical methods to manage and analyze the biological data. The fundamental issues that directly impact an understanding of life at structural, functional and molecular level, and regulation of gene expression can be studied by using bioinformatics tools. The Fundamentals of Bioinformatics is a comprehensive book for undergraduates, postgraduates and research scholars, who urge to learn about theoretical as well as practical aspects of this upcoming field. This pioneering book provides up-to-date information on bioinformatics and emphasizes recent topics like drug design technology, pharmacogenomics, proteomics and genomics. The present textbook will be an asset to Life sciences and technology institutions, since it has been designed based on the prescribed syllabus of various Indian Universities and aboard, and cover all the important topics on Bioinformatics.

Bioinformatics and Computational Biology

Author : Basant K. Tiwary
Publisher : Unknown
Page : 0 pages
File Size : 44,5 Mb
Release : 2022
Category : Electronic
ISBN : 9811642427

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Bioinformatics and Computational Biology by Basant K. Tiwary Pdf

This textbook introduces fundamental concepts of bioinformatics and computational biology to the students and researchers in biology, medicine, veterinary science, agriculture, and bioengineering . The respective chapters provide detailed information on biological databases, sequence alignment, molecular evolution, next-generation sequencing, systems biology, and statistical computing using R. The book also presents a case-based discussion on clinical, veterinary, agricultural bioinformatics, and computational bioengineering for application-based learning in the respective fields. Further, it offers readers guidance on reconstructing and analysing biological networks and highlights computational methods used in systems medicine and genome-wide association mapping of diseases. Given its scope, this textbook offers an essential introductory book on bioinformatics and computational biology for undergraduate and graduate students in the life sciences, botany, zoology, physiology, biotechnology, bioinformatics, and genomic science as well as systems biology, bioengineering and the agricultural, and veterinary sciences.

Fundamental Concepts of Bioinformatics

Author : Dan E. Krane,Michael L. Raymer
Publisher : Unknown
Page : 314 pages
File Size : 42,8 Mb
Release : 2003
Category : Bioinformatics
ISBN : 032119022X

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Fundamental Concepts of Bioinformatics by Dan E. Krane,Michael L. Raymer Pdf

Co-authored by a biologist and computer scientist, this book is designed to make bioinformatics useful to undergraduates and prepare them for more advanced work. It covers problems at the end of each chapter, which use real data to help students apply what they have learned from both a statistical and biological point of view.

Bioinformatics

Author : Hamid D. Ismail
Publisher : CRC Press
Page : 466 pages
File Size : 43,9 Mb
Release : 2022-03-23
Category : Science
ISBN : 9781000519075

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Bioinformatics by Hamid D. Ismail Pdf

Bioinformatics: A Practical Guide to NCBI Databases and Sequence Alignments provides the basics of bioinformatics and in-depth coverage of NCBI databases, sequence alignment, and NCBI Sequence Local Alignment Search Tool (BLAST). As bioinformatics has become essential for life sciences, the book has been written specifically to address the need of a large audience including undergraduates, graduates, researchers, healthcare professionals, and bioinformatics professors who need to use the NCBI databases, retrieve data from them, and use BLAST to find evolutionarily related sequences, sequence annotation, construction of phylogenetic tree, and the conservative domain of a protein, to name just a few. Technical details of alignment algorithms are explained with a minimum use of mathematical formulas and with graphical illustrations. Key Features Provides readers with the most-used bioinformatics knowledge of bioinformatics databases and alignments including both theory and application via illustrations and worked examples. Discusses the use of Windows Command Prompt, Linux shell, R, and Python for both Entrez databases and BLAST. The companion website contains tutorials, R and Python codes, instructor materials including slides, exercises, and problems for students. This is the ideal textbook for bioinformatics courses taken by students of life sciences and for researchers wishing to develop their knowledge of bioinformatics to facilitate their own research.

Bioinformatics for Systems Biology

Author : Stephen Krawetz
Publisher : Springer Science & Business Media
Page : 639 pages
File Size : 49,8 Mb
Release : 2008-12-11
Category : Science
ISBN : 9781597454407

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Bioinformatics for Systems Biology by Stephen Krawetz Pdf

Bioinformatics for Systems Biology bridges and unifies many disciplines. It presents the life scientist, computational biologist, and mathematician with a common framework. Only by linking the groups together may the true life sciences revolution move forward.

Fundamental Concepts of Bioinformatics

Author : Dan E. Krane,Michael L. Raymer
Publisher : Pearson
Page : 336 pages
File Size : 43,8 Mb
Release : 2002
Category : Computers
ISBN : UOM:39015055857984

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Fundamental Concepts of Bioinformatics by Dan E. Krane,Michael L. Raymer Pdf

Information flows easily from one topic to the next, with enough detail to support the major concepts without overwhelming students."--BOOK JACKET.

Introduction to Bioinformatics

Author : Anna Tramontano
Publisher : CRC Press
Page : 196 pages
File Size : 42,9 Mb
Release : 2006-12-06
Category : Science
ISBN : 1584885696

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Introduction to Bioinformatics by Anna Tramontano Pdf

Guiding readers from the elucidation and analysis of a genomic sequence to the prediction of a protein structure and the identification of the molecular function, Introduction to Bioinformatics describes the rationale and limitations of the bioinformatics methods and tools that can help solve biological problems. Requiring only a limited mathematical and statistical background, the book shows how to efficiently apply these approaches to biological data and evaluate the resulting information. The author, an expert bioinformatics researcher, first addresses the ways of storing and retrieving the enormous amount of biological data produced every day and the methods of decrypting the information encoded by a genome. She then covers the tools that can detect and exploit the evolutionary and functional relationships among biological elements. Subsequent chapters illustrate how to predict the three-dimensional structure of a protein. The book concludes with a discussion of the future of bioinformatics. Even though the future will undoubtedly offer new tools for tackling problems, most of the fundamental aspects of bioinformatics will not change. This resource provides the essential information to understand bioinformatics methods, ultimately facilitating in the solution of biological problems.

Bioinformatics for Beginners

Author : Supratim Choudhuri
Publisher : Elsevier
Page : 238 pages
File Size : 42,7 Mb
Release : 2014-05-09
Category : Medical
ISBN : 9780124105102

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Bioinformatics for Beginners by Supratim Choudhuri Pdf

Bioinformatics for Beginners: Genes, Genomes, Molecular Evolution, Databases and Analytical Tools provides a coherent and friendly treatment of bioinformatics for any student or scientist within biology who has not routinely performed bioinformatic analysis. The book discusses the relevant principles needed to understand the theoretical underpinnings of bioinformatic analysis and demonstrates, with examples, targeted analysis using freely available web-based software and publicly available databases. Eschewing non-essential information, the work focuses on principles and hands-on analysis, also pointing to further study options. Avoids non-essential coverage, yet fully describes the field for beginners Explains the molecular basis of evolution to place bioinformatic analysis in biological context Provides useful links to the vast resource of publicly available bioinformatic databases and analysis tools Contains over 100 figures that aid in concept discovery and illustration

An Introduction to Bioinformatics Algorithms

Author : Neil C. Jones,Pavel A. Pevzner
Publisher : MIT Press
Page : 460 pages
File Size : 48,6 Mb
Release : 2004-08-06
Category : Computers
ISBN : 0262101068

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An Introduction to Bioinformatics Algorithms by Neil C. Jones,Pavel A. Pevzner Pdf

An introductory text that emphasizes the underlying algorithmic ideas that are driving advances in bioinformatics. This introductory text offers a clear exposition of the algorithmic principles driving advances in bioinformatics. Accessible to students in both biology and computer science, it strikes a unique balance between rigorous mathematics and practical techniques, emphasizing the ideas underlying algorithms rather than offering a collection of apparently unrelated problems. The book introduces biological and algorithmic ideas together, linking issues in computer science to biology and thus capturing the interest of students in both subjects. It demonstrates that relatively few design techniques can be used to solve a large number of practical problems in biology, and presents this material intuitively. An Introduction to Bioinformatics Algorithms is one of the first books on bioinformatics that can be used by students at an undergraduate level. It includes a dual table of contents, organized by algorithmic idea and biological idea; discussions of biologically relevant problems, including a detailed problem formulation and one or more solutions for each; and brief biographical sketches of leading figures in the field. These interesting vignettes offer students a glimpse of the inspirations and motivations for real work in bioinformatics, making the concepts presented in the text more concrete and the techniques more approachable.PowerPoint presentations, practical bioinformatics problems, sample code, diagrams, demonstrations, and other materials can be found at the Author's website.

Introduction to Computational Biology

Author : Bernhard Haubold,Thomas Wiehe
Publisher : Springer Science & Business Media
Page : 329 pages
File Size : 40,8 Mb
Release : 2006-08-09
Category : Science
ISBN : 9783764373870

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Introduction to Computational Biology by Bernhard Haubold,Thomas Wiehe Pdf

Written with the advanced undergraduate in mind, this book introduces into the field of Bioinformatics. The authors explain the computational and conceptional background to the analysis of large-scale sequence data. Many of the corresponding analysis methods are rooted in evolutionary thinking, which serves as a common thread throughout the book. The focus is on methods of comparative genomics and subjects covered include: alignments, gene finding, phylogeny, and the analysis of single nucleotide polymorphisms (SNPs). The volume contains exercises, questions & answers to selected problems.

Fundamentals of Systems Biology

Author : Markus W. Covert
Publisher : CRC Press
Page : 367 pages
File Size : 48,7 Mb
Release : 2017-10-19
Category : Technology & Engineering
ISBN : 9781498728478

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Fundamentals of Systems Biology by Markus W. Covert Pdf

For decades biology has focused on decoding cellular processes one gene at a time, but many of the most pressing biological questions, as well as diseases such as cancer and heart disease, are related to complex systems involving the interaction of hundreds, or even thousands, of gene products and other factors. How do we begin to understand this complexity? Fundamentals of Systems Biology: From Synthetic Circuits to Whole-cell Models introduces students to methods they can use to tackle complex systems head-on, carefully walking them through studies that comprise the foundation and frontier of systems biology. The first section of the book focuses on bringing students quickly up to speed with a variety of modeling methods in the context of a synthetic biological circuit. This innovative approach builds intuition about the strengths and weaknesses of each method and becomes critical in the book’s second half, where much more complicated network models are addressed—including transcriptional, signaling, metabolic, and even integrated multi-network models. The approach makes the work much more accessible to novices (undergraduates, medical students, and biologists new to mathematical modeling) while still having much to offer experienced modelers--whether their interests are microbes, organs, whole organisms, diseases, synthetic biology, or just about any field that investigates living systems.

Computational Genome Analysis

Author : Richard C. Deonier,Simon Tavaré,Michael S. Waterman
Publisher : Springer Science & Business Media
Page : 542 pages
File Size : 52,8 Mb
Release : 2005-12-27
Category : Computers
ISBN : 9780387288079

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Computational Genome Analysis by Richard C. Deonier,Simon Tavaré,Michael S. Waterman Pdf

This book presents the foundations of key problems in computational molecular biology and bioinformatics. It focuses on computational and statistical principles applied to genomes, and introduces the mathematics and statistics that are crucial for understanding these applications. The book features a free download of the R software statistics package and the text provides great crossover material that is interesting and accessible to students in biology, mathematics, statistics and computer science. More than 100 illustrations and diagrams reinforce concepts and present key results from the primary literature. Exercises are given at the end of chapters.

Bioinformatics

Author : Jeremy Ramsden
Publisher : Springer Science & Business Media
Page : 274 pages
File Size : 52,7 Mb
Release : 2009-04-29
Category : Science
ISBN : 9781848002579

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Bioinformatics by Jeremy Ramsden Pdf

The field of bioinformatics continues to develop energetically. This second edition covers new findings using the formula of the original text. It is self-contained, bringing together the multiple disciplines necessary for a profound grasp of the field.