Fundamentals Of Tissue Engineering And Regenerative Medicine

Author : Ulrich Meyer,Thomas Meyer,Jörg Handschel,Hans Peter Wiesmann
Publisher : Springer Science & Business Media
Page : 1049 pages
File Size : 41,7 Mb
Release : 2009-02-11
Category : Medical
ISBN : 9783540777557

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Fundamentals of Tissue Engineering and Regenerative Medicine by Ulrich Meyer,Thomas Meyer,Jörg Handschel,Hans Peter Wiesmann Pdf

"Fundamentals of Tissue Engineering and Regenerative Medicine" provides a complete overview of the state of the art in tissue engineering and regenerative medicine. Tissue engineering has grown tremendously during the past decade. Advances in genetic medicine and stem cell technology have significantly improved the potential to influence cell and tissue performance, and have recently expanded the field towards regenerative medicine. In recent years a number of approaches have been used routinely in daily clinical practice, others have been introduced in clinical studies, and multitudes are in the preclinical testing phase. Because of these developments, there is a need to provide comprehensive and detailed information for researchers and clinicians on this rapidly expanding field. This book offers, in a single volume, the prerequisites of a comprehensive understanding of tissue engineering and regenerative medicine. The book is conceptualized according to a didactic approach (general aspects: social, economic, and ethical considerations; basic biological aspects of regenerative medicine: stem cell medicine, biomolecules, genetic engineering; classic methods of tissue engineering: cell, tissue, organ culture; biotechnological issues: scaffolds; bioreactors, laboratory work; and an extended medical discipline oriented approach: review of clinical use in the various medical specialties). The content of the book, written in 68 chapters by the world’s leading research and clinical specialists in their discipline, represents therefore the recent intellect, experience, and state of this bio-medical field.

Author : John P. Fisher,Antonios G. Mikos,Joseph D. Bronzino,Donald R. Peterson
Publisher : CRC Press
Page : 801 pages
File Size : 53,6 Mb
Release : 2012-12-11
Category : Medical
ISBN : 9781439874004

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Tissue Engineering by John P. Fisher,Antonios G. Mikos,Joseph D. Bronzino,Donald R. Peterson Pdf

Tissue engineering research continues to captivate the interest of researchers and the general public alike. Popular media outlets like The New York Times, Time, and Wired continue to engage a wide audience and foster excitement for the field as regenerative medicine inches toward becoming a clinical reality. Putting the numerous advances in the field into a broad context, Tissue Engineering: Principles and Practices explores current thoughts on the development of engineered tissues. With contributions from experts and pioneers, this book begins with coverage of the fundamentals, details the supporting technology, and then elucidates their applications in tissue engineering. It explores strategic directions, nanobiomaterials, biomimetics, gene therapy, cell engineering, and more. The chapters then explore the applications of these technologies in areas such as bone engineering, cartilage tissue, dental tissue, vascular engineering, and neural engineering. A comprehensive overview of major research topics in tissue engineering, the book: Examines the properties of stem cells, primary cells, growth factors, and extracellular matrix as well as their impact on the development of tissue-engineered devices Focuses upon those strategies typically incorporated into tissue-engineered devices or utilized in their development, including scaffolds, nanocomposites, bioreactors, drug delivery systems, and gene therapy techniques Presents synthetic tissues and organs that are currently under development for regenerative medicine applications The contributing authors are a diverse group with backgrounds in academia, clinical medicine, and industry. Furthermore, this book includes contributions from Europe, Asia, and North America, helping to broaden the views on the development and application of tissue-engineered devices. The book provides a useful reference for courses devoted to tissue engineering fundamentals and those laboratories developing tissue-engineered devices for regenerative medicine therapy.

Author : Robert Lanza,Robert Langer,Joseph P. Vacanti
Publisher : Elsevier
Page : 995 pages
File Size : 44,7 Mb
Release : 2000-05-16
Category : Science
ISBN : 9780080539676

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Principles of Tissue Engineering by Robert Lanza,Robert Langer,Joseph P. Vacanti Pdf

The opportunity that tissue engineering provides for medicine is extraordinary. In the United States alone, over half-a-trillion dollars are spent each year to care for patients who suffer from tissue loss or dysfunction. Although numerous books and reviews have been written on tissue engineering, none has been as comprehensive in its defining of the field. Principles of Tissue Engineering combines in one volume the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation of applications of tissue engineering to diseases affecting specific organ systems. The first edition of the book, published in 1997, is the definite reference in the field. Since that time, however, the discipline has grown tremendously, and few experts would have been able to predict the explosion in our knowledge of gene expression, cell growth and differentiation, the variety of stem cells, new polymers and materials that are now available, or even the successful introduction of the first tissue-engineered products into the marketplace. There was a need for a new edition, and this need has been met with a product that defines and captures the sense of excitement, understanding and anticipation that has followed from the evolution of this fascinating and important field. Key Features * Provides vast, detailed analysis of research on all of the major systems of the human body, e.g., skin, muscle, cardiovascular, hematopoietic, and nerves * Essential to anyone working in the field * Educates and directs both the novice and advanced researcher * Provides vast, detailed analysis of research with all of the major systems of the human body, e.g. skin, muscle, cardiovascular, hematopoietic, and nerves * Has new chapters written by leaders in the latest areas of research, such as fetal tissue engineering and the universal cell * Considered the definitive reference in the field * List of contributors reads like a "who's who" of tissue engineering, and includes Robert Langer, Joseph Vacanti, Charles Vacanti, Robert Nerem, A. Hari Reddi, Gail Naughton, George Whitesides, Doug Lauffenburger, and Eugene Bell, among others

Author : Ranjna C Dutta,Aroop K Dutta
Publisher : Pan Stanford
Page : 128 pages
File Size : 40,6 Mb
Release : 2018
Category : Cell culture
ISBN : OCLC:1101139541

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3D Cell Culture by Ranjna C Dutta,Aroop K Dutta Pdf

Author : Ravi Birla
Publisher : John Wiley & Sons
Page : 360 pages
File Size : 44,9 Mb
Release : 2014-06-05
Category : Science
ISBN : 9781118629697

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Introduction to Tissue Engineering by Ravi Birla Pdf

A comprehensive reference and teaching aid on tissueengineering—covering everything from the basics ofregenerative medicine to more advanced and forward thinking topicssuch as the artificial liver, bladder, and trachea Regenerative medicine/tissue engineering is the process ofreplacing or regenerating human cells, tissues, or organs torestore or establish normal function. It is an incrediblyprogressive field of medicine that may, in the near future, helpwith the shortage of life-saving organs available through donationfor transplantation. Introduction to Tissue Engineering: Applications andChallenges makes tissue engineering more accessible toundergraduate and graduate students alike. It provides a systematicand logical eight-step process for tissue fabrication. Specificchapters have been dedicated to provide in-depth principles formany of the supporting and enabling technologies during the tissuefabrication process and include biomaterial development andsynthesis, bioreactor design, and tissue vascularization. Thetissue fabrication process is further illustrated with specificexamples for liver, bladder, and trachea. Section-coverage includesan overall introduction of tissue engineering; enabling andsupporting technologies; clinical applications; and case studiesand future challenges. Introduction to Tissue Engineering: Presents medical applications of stem cells in tissueengineering Deals with the effects of chemical stimulation (growthfactors and hormones) Covers current disease pathologies and treatment options(pacemakers, prosthesis) Explains bioengineering, design and fabrication, andcritical challenges during tissue fabrication Offers PowerPoint slides for instructors Features case studies and a section on future directions andchallenges As pioneering individuals look ahead to the possibility ofgenerating entire organ systems, students may turn to this text fora comprehensive understanding and preparation for the future ofregenerative medicine.

Author : Yoshito Ikada
Publisher : Elsevier
Page : 490 pages
File Size : 45,7 Mb
Release : 2011-08-29
Category : Technology & Engineering
ISBN : 9780080464008

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Tissue Engineering by Yoshito Ikada Pdf

Tissue engineering is an emerging interdisciplinary field, occupying a major position in the regenerative medicine that aims at restoring lost or damaged tissues and organs with use of cells. Regenerative medicine includes cellular therapy and tissue engineering. In general, the former treats patients by cell infusion alone, while tissue engineering needs biomaterials and growth factors in addition to cells. Biomaterials function in tissue engineering as the scaffold or template for cells to proliferate, differentiate, and produce matrices. Tissue Engineering focuses on the fundamentals (biomaterials, scaffolds, cell cultures, bioreactors, animal models etc.), recent animal and human trials, and future prospects regarding tissue engineering. Almost twenty years have passed since the advent of the tissue engineering, whicht uses cells, scaffolds, and growth factors for regeneration of neotissues. The number of investigations on tissue engineering is still increasing tremendously. Nevertheless, it seems likely that the number of reports describing clinical trials of tissue engineering will remain very limited. Even the studies that apply tissue engineering research to large animals have not been performed yet on a large scale. The major objective of this book is to address this question from a science and technology point of view, and to describe the principles of basic technologies that have currently been developed by numerous research groups. Helps reader understand the key issues required for promotion of clinical trials in tissue engineering Covers in full the issues related to tissue engineering Looking at current technologies in the field

Author : Chandra P. Sharma,Thomas Chandy,Vinoy Thomas,Finosh G. Thankam
Publisher : Academic Press
Page : 724 pages
File Size : 43,7 Mb
Release : 2022-01-25
Category : Science
ISBN : 9780128240656

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Tissue Engineering by Chandra P. Sharma,Thomas Chandy,Vinoy Thomas,Finosh G. Thankam Pdf

Tissue Engineering: Current Status and Challenges bridges the gap between biomedical scientists and clinical practitioners. The work reviews the history of tissue engineering, covers the basics required for the beginner, and inspires those in the field toward future research and application emerging in this fast-moving field. Written by global experts in the field for those studying and researching tissue engineering, the book reviews regenerative technologies, stem cell research and regeneration of organs. It then moves to soft tissue engineering (heart, vascular, muscle and 3D scaffolding and printing), hard tissue engineering (bone, dental myocardial and musculoskeletal) and translational avenues in the field. Introduces readers to the history and benefits of tissue engineering Includes coverage of new techniques and technologies, such as nanotechnology and nanoengineering Presents concepts, ideology and theories which form the foundation for next-generation tissue engineering

Author : J. Miguel Oliveira,Joana Silva-Correia,Rui L. Reis
Publisher : Academic Press
Page : 851 pages
File Size : 43,9 Mb
Release : 2023-09-29
Category : Science
ISBN : 9780128242254

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Hydrogels for Tissue Engineering and Regenerative Medicine by J. Miguel Oliveira,Joana Silva-Correia,Rui L. Reis Pdf

Hydrogels for Tissue Engineering and Regenerative Medicine: From Fundaments to Applications provides the reader with a comprehensive, concise and thoroughly up-to-date resource on the different types of hydrogels in tissue engineering and regenerative medicine. The book is divided into three main sections that describe biological activities and the structural and physicochemical properties of hydrogels, along with a wide range of applications, including their combination with emerging technologies. Written by a diverse range of international academics for professionals, researchers, undergraduate and graduate students, this groundbreaking publication fills a gap in literature needed in the tissue engineering and regenerative medicine field. Reviews the fundamentals and recent advances of hydrogels in tissue engineering and regenerative medicine applications Presents state-of-the-art methodologies for the synthesis and processing of different types of hydrogels Includes contributions by leading experts in engineering, the life sciences, microbiology and clinical medicine

Author : Alain A. Vertes,Nasib Qureshi,Arnold I. Caplan,Lee E. Babiss
Publisher : John Wiley & Sons
Page : 788 pages
File Size : 46,7 Mb
Release : 2015-12-02
Category : Science
ISBN : 9781119971399

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Stem Cells in Regenerative Medicine by Alain A. Vertes,Nasib Qureshi,Arnold I. Caplan,Lee E. Babiss Pdf

This book is a unique guide to emerging stem cell technologies and the opportunities for their commercialisation. It provides in-depth analyses of the science, business, legal, and financing fundamentals of stem cell technologies, offering a holistic assessment of this emerging and dynamic segment of the field of regenerative medicine. • Reviews the very latest advances in the technology and business of stem cells used for therapy, research, and diagnostics • Identifies key challenges to the commercialisation of stem cell technology and avenues to overcome problems in the pipeline • Written by an expert team with extensive experience in the business, basic and applied science of stem cell research This comprehensive volume is essential reading for researchers in cell biology, biotechnology, regenerative medicine, and tissue engineering, including scientists and professionals, looking to enter commercial biotechnology fields.

Author : Vasif Hasirci,Nesrin Hasirci
Publisher : Springer
Page : 338 pages
File Size : 46,9 Mb
Release : 2018-11-26
Category : Technology & Engineering
ISBN : 9781493988563

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Fundamentals of Biomaterials by Vasif Hasirci,Nesrin Hasirci Pdf

This text for advanced undergraduate and graduate students covers the fundamental relationships between the structure and properties of materials and biological tissues. The successful integration of material and biological properties, shape, and architecture to engineer a wide range of optimized designs for specific functions is the ultimate aim of a biomaterials scientist. Relevant examples illustrate the intrinsic and tailored properties of metal, ceramic, polymeric, carbon-derived, composite, and naturally derived biomaterials. Fundamentals of Biomaterials is written in a single voice, ensuring clarity and continuity of the text and content. As a result, the reader will be gradually familiarized with the field, starting with materials and their properties and eventually leading to critical interactions with the host environment. Classical and novel examples illuminate topics from basic material properties to tissue engineering, nanobiomaterials, and guided tissue regeneration. This comprehensive and engaging text: integrates materials and biological properties to understand biomaterials function and design provides the basics of biological tissue components and hierarchy includes recent topics from tissue engineering and guided tissue regeneration to nanoarchitecture of biomaterials and their surfaces contains perspectives/case studies from widely-recognized experts in the field features chapter-ending summaries to help readers to identify the key, take-home messages.

Author : Sundar Madihally
Publisher : Academic Press
Page : 0 pages
File Size : 41,8 Mb
Release : 2014-02-26
Category : Medical
ISBN : 0123854849

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Fundamentals of Tissue Engineering by Sundar Madihally Pdf

This book is written as an introduction to tissue engineering using engineering and biological principles, and covers fundamental concepts useful for tissue regeneration, along with examples and strategies to engineer specific tissues for clinical use. It maintains a consistent voice, style, and nomenclature throughout the text to minimize confusion, and importantly, it integrates concepts across chapters. Unique features and benefits: Feature: Begins with fundamentals and builds basic principles that are broadly applicable to a variety of tissue engineering strategies Benefit: appropriate for a wide variety of courses at undergrad or grad level, providing necessary detail for readers with different backgrounds Feature: Develops and maintains consistent level, writing style, and nomenclature throughout the text Benefit: Consistent depth across chapters, minimizes confusion that may result from other texts that have multiple contributors/multiple writing styles. Feature: Integrates concepts across chapters Benefit: Shows how fundamentals can be applied to various tissue engineering strategies Feature: Largest number of worked examples and end of chapter exercises Benefit: help develop problem solving skills Feature: Four case studies cover skin, bone, cartilage, and tubular tissue engineering Benefit: Shows clinical applications of concepts, integrates all concepts from earlier in the text to real-life situations

Author : Subhas Kundu
Publisher : Elsevier
Page : 582 pages
File Size : 52,5 Mb
Release : 2014-03-24
Category : Medical
ISBN : 9780857097064

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Silk Biomaterials for Tissue Engineering and Regenerative Medicine by Subhas Kundu Pdf

Silk is increasingly being used as a biomaterial for tissue engineering applications, as well as sutures, due to its unique mechanical and chemical properties. Silk Biomaterials for Tissue Engineering and Regenerative Medicine discusses the properties of silk that make it useful for medical purposes and its applications in this area. Part one introduces silk biomaterials, discussing their fundamentals and how they are processed, and considering different types of silk biomaterials. Part two focuses on the properties and behavior of silk biomaterials and the implications of this for their applications in biomedicine. These chapters focus on topics including biodegradation, bio-response to silk sericin, and capillary growth behavior in porous silk films. Finally, part three discusses the applications of silk biomaterials for tissue engineering, regenerative medicine, and biomedicine, with chapters on the use of silk biomaterials for vertebral, dental, dermal, and cardiac tissue engineering. Silk Biomaterials for Tissue Engineering and Regenerative Medicine is an important resource for materials and tissue engineering scientists, R&D departments in industry and academia, and academics with an interest in the fields of biomaterials and tissue engineering. Discusses the properties and applications of silk for medical purposes Considers pharmaceutical and cosmeceutical applications

Author : Anthony Atala,Robert Lanza
Publisher : Gulf Professional Publishing
Page : 580 pages
File Size : 54,7 Mb
Release : 2001-10-12
Category : Science
ISBN : 9780124366367

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Methods of Tissue Engineering by Anthony Atala,Robert Lanza Pdf

This reference book combines the tools, experimental protocols, detailed descriptions and know-how for the successful engineering of tissues and organs in one volume.

Author : Clemens Van Blitterswijk,Jan De Boer
Publisher : Academic Press
Page : 896 pages
File Size : 45,9 Mb
Release : 2014-12-10
Category : Technology & Engineering
ISBN : 9780124202108

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Tissue Engineering by Clemens Van Blitterswijk,Jan De Boer Pdf

Tissue Engineering is a comprehensive introduction to the engineering and biological aspects of this critical subject. With contributions from internationally renowned authors, it provides a broad perspective on tissue engineering for students coming to the subject for the first time. In addition to the key topics covered in the previous edition, this update also includes new material on the regulatory authorities, commercial considerations as well as new chapters on microfabrication, materiomics and cell/biomaterial interface. Effectively reviews major foundational topics in tissue engineering in a clear and accessible fashion Includes state of the art experiments presented in break-out boxes, chapter objectives, chapter summaries, and multiple choice questions to aid learning New edition contains material on regulatory authorities and commercial considerations in tissue engineering

Author : Anwarul Hasan
Publisher : John Wiley & Sons
Page : 754 pages
File Size : 42,7 Mb
Release : 2017-03-28
Category : Science
ISBN : 9783527689941

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Tissue Engineering for Artificial Organs by Anwarul Hasan Pdf

A comprehensive overview of the latest achievements, trends, and the current state of the art of this important and rapidly expanding field. Clearly and logically structured, the first part of the book explores the fundamentals of tissue engineering, providing a separate chapter on each of the basic topics, including biomaterials stem cells, biosensors and bioreactors. The second part then follows a more applied approach, discussing various applications of tissue engineering, such as the replacement or repairing of skins, cartilages, livers and blood vessels, to trachea, lungs and cardiac tissues, to musculoskeletal tissue engineering used for bones and ligaments as well as pancreas, kidney and neural tissue engineering for the brain. The book concludes with a look at future technological advances. An invaluable reading for entrants to the field in biomedical engineering as well as expert researchers and developers in industry.