Gene Technology And Gene Therapy In Dermatology

Author : Ulrich R. Hengge
Publisher : S. Karger AG (Switzerland)
Page : 72 pages
File Size : 46,5 Mb
Release : 2002-01-01
Category : Medical
ISBN : 3805574940

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Gene Technology and Gene Therapy in Dermatology by Ulrich R. Hengge Pdf

Basic concepts and recent advances in the field In recent years the skin has become an important target organ of gene technology and gene therapy. Its easy accessibility, well-established culture conditions and grafting techniques, as well as its function as an immune organ make it a promising candidate for the development of innovative treatment strategies. This special issue of Cells Tissues Organs gives an overview of the latest achievements in the field of skin gene therapy focusing on basic research and initial preclinical applications. It describes novel techniques of generating epidermal equivalents from hair follicle cells, the reaction of keratinocytes to exogenous DNA, and the genetic engineering of skin to be used as a bioreactor or a metabolic sink' in the treatment of metabolic disorders. Further potential applications of skin gene therapy include the treatment of chronic wounds, hypertrophic scars, keloids, and cancer, as well as its role in soft tissue reconstruction. Since gene therapy is a truly interdisciplinary field, this publication is recommended reading not only for dermatologists, geneticists, bioengineers, cell biologists and immunologists, but also for clinicians with an interest in cancer, metabolic diseases, skin biology and tissue engineering.

Author : Ulrich R. Hengge,Beatrix Volc-Platzer
Publisher : Springer Science & Business Media
Page : 301 pages
File Size : 44,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642564413

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The Skin and Gene Therapy by Ulrich R. Hengge,Beatrix Volc-Platzer Pdf

This first comprehensive guide to the novel field of gene therapy in the skin provides insight into the basic principles and methods of gene transfer into the skin and its applications. It enables the understanding of possibilities and implications such as immunization and treatment as well as safety aspects. Gene therapy in dermatology is the avantgarde of a new field in science with a great future for human health.

Author : Lawrence S. Chan,M. Peter Marinkovich
Publisher : CRC Press
Page : 170 pages
File Size : 42,9 Mb
Release : 2021-08-01
Category : Medical
ISBN : 9781000460681

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New Technologies in Dermatological Science and Practice by Lawrence S. Chan,M. Peter Marinkovich Pdf

While science and technology have been moving at speed in the last decade and major investments have been placed in Artificial Intelligence, blockchain technology, 3D printing, and gene editing, medical practice, including cutaneous medicine (otherwise known as Dermatology), is only just starting to follow these technological advances. This book is a timely intellectual investment for cutaneous medicine, addressing these particularly needed areas. It is written for medical educators, dermatology residents, practicing dermatologists, and medical researchers in the area of skin diseases, to alert them all to medical advances and up-and-coming technology and in the hope, it will inspire further novel methodology for the future of cutaneous medicine, in diagnosis and therapy.

Author : Ulrich R. Hengge
Publisher : S Karger Ag
Page : 88 pages
File Size : 53,5 Mb
Release : 2004
Category : Science
ISBN : 3805578059

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Progress in Gene Technology and Skin Gene Therapy by Ulrich R. Hengge Pdf

Significant progress has been made in gene technology and skin gene therapy in the last few years. Besides the development of suitable animal models, novel molecular technologies such as small inhibitory RNA are discussed, which enable the modification of sequence-specific gene expression. Progress is reported in the field of DNA vaccination against HIV-1 as well as in the correction of xeroderma pigmentosum using retroviral-based gene transfer. In addition to gene technology and skin gene therapy, recent advances in molecular diagnostics of malignancy are described. Microarray-based gene expression profiling is a powerful technology with which up to 22,000 genes can simultaneously be analyzed in a given tissue. It is used today by several groups to characterize malignant melanoma and other tumors on a molecular level, identifying important dysregulated pathways and gene products and comparing them with those of normal human melanocytes and benign nevi. Providing an overview of the latest techniques and achievements in the field, this publication is recommended to dermatologists, geneticists, bioengineers, cell biologists and immunologists, and anyone interested in learning more about new molecular approaches in biomedicine.

Author : Patricia L. Chang
Publisher : CRC Press
Page : 318 pages
File Size : 42,5 Mb
Release : 1994-12-27
Category : Science
ISBN : 0849324408

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Somatic Gene Therapy by Patricia L. Chang Pdf

As human gene therapy becomes a clinical reality, a new era in medicine dawns. Novel and innovative developments in molecular genetics now provide opportunities to treat the genetic bases of diseases often untreatable before. Somatic Gene Therapy documents these historical clinical trials, reviews current advances in the field, evaluates the use of the many different cell types and organs amenable to gene transfer, and examines the prospects of various exciting strategies for gene therapy.

Author : Celia Moss,John Savin
Publisher : Wiley-Blackwell
Page : 208 pages
File Size : 40,5 Mb
Release : 1995-07-12
Category : Medical
ISBN : 063203582X

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Dermatology and the New Genetics by Celia Moss,John Savin Pdf

Dermatologists, unlike, for instance, haematologists, are not generally trained in high science and tend to be unfamiliar with the language of the "New Genetics". Lacking an interpreter, they can neither understand nor exploit the exciting developments in this field. This two-author volume gives a straight-forward and uniform account of the subject. Relevant and accessible to clinical dermatologists, the text begins with a refresher course in simple background genetics and the development of skin in this context. It goes on, in the two largest sections of the book, to look at the genetics of epidermal and dermal skin disorders; each of these sections is divided into groups of conditions. The final section describes antenatal diagnosis, counselling and gene therapy. The theme of this book is to bridge the gap between clinical dermatology and the new genetics. It provides a straightforward and uniform account of the subject, relevant and accessible to clinical dermatologists, beginning with a refresher course in simple background genetics and the development of skin in this context

Author : Joshua Boateng
Publisher : John Wiley & Sons
Page : 444 pages
File Size : 44,8 Mb
Release : 2020-03-09
Category : Science
ISBN : 9781119433262

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Therapeutic Dressings and Wound Healing Applications by Joshua Boateng Pdf

The latest research on techniques for effective healing of chronic and difficult to heal wounds The healing of chronic wounds is a global medical concern, specifically for patients suffering from obesity and type II diabetes. Therapeutic Dressing and Wound Healing Applications is an essential text for research labs, industry professionals, and general clinical practitioners that want to make the shift towards advanced therapeutic dressing and groundbreaking wound application for better healing. This book takes a clinical and scientific approach to wound healing, and includes recent case studies to highlight key points and areas of improvement. It is divided into two key sections that include insight into the biochemical basis of wounds, as well as techniques and recent advancements. Chapters include information on: ● Debridement and disinfection properties of wound dressing ● Biofilms, silver nanoparticles, and honey dressings ● Clinical perspectives for treating diabetic wounds ● Treating mixed infections ● Wound healing and tissue regeneration treatments ● Gene based therapy, 3D bioprinting and freeze-dried wafers Anyone looking to update and improve the treatment of chronic wounds for patients will find the latest pertinent information in Therapeutic Dressing and Wound Healing Applications.

Author : Institute of Medicine,Board on Health Sciences Policy,Committee on the Independent Review and Assessment of the Activities of the NIH Recombinant DNA Advisory Committee
Publisher : National Academies Press
Page : 134 pages
File Size : 54,7 Mb
Release : 2014-03-27
Category : Medical
ISBN : 9780309296656

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Oversight and Review of Clinical Gene Transfer Protocols by Institute of Medicine,Board on Health Sciences Policy,Committee on the Independent Review and Assessment of the Activities of the NIH Recombinant DNA Advisory Committee Pdf

Gene transfer research is a rapidly advancing field that involves the introduction of a genetic sequence into a human subject for research or diagnostic purposes. Clinical gene transfer trials are subject to regulation by the U.S. Food and Drug Administration (FDA) at the federal level and to oversight by institutional review boards (IRBs) and institutional biosafety committees (IBCs) at the local level before human subjects can be enrolled. In addition, at present all researchers and institutions funded by the National Institutes of Health (NIH) are required by NIH guidelines to submit human gene transfer protocols for advisory review by the NIH Recombinant DNA Advisory Committee (RAC). Some protocols are then selected for individual review and public discussion. Oversight and Review of Clinical Gene Transfer Protocols provides an assessment of the state of existing gene transfer science and the current regulatory and policy context under which research is investigated. This report assesses whether the current oversight of individual gene transfer protocols by the RAC continues to be necessary and offers recommendations concerning the criteria the NIH should employ to determine whether individual protocols should receive public review. The focus of this report is on the standards the RAC and NIH should use in exercising its oversight function. Oversight and Review of Clinical Gene Transfer Protocols will assist not only the RAC, but also research institutions and the general public with respect to utilizing and improving existing oversight processes.

Author : Somesh Gupta
Publisher : Springer Nature
Page : 369 pages
File Size : 43,6 Mb
Release : 2024-06-23
Category : Electronic
ISBN : 9789819704118

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Critical Thinking in Contemporary Dermatology: Cognitive Essays by Somesh Gupta Pdf

Author : Adnan Nasir,Adam Friedman,Steven Wang
Publisher : Springer Science & Business Media
Page : 299 pages
File Size : 43,9 Mb
Release : 2012-12-02
Category : Medical
ISBN : 9781461450344

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Nanotechnology in Dermatology by Adnan Nasir,Adam Friedman,Steven Wang Pdf

Nanotechnology in Dermatology is the first book of its kind to address all of the important and rapidly growing aspects of nanotechnology as it relates to dermatology. In the last few years there has been an explosion in research and development for products and devices related to nanotechnology, including numerous applications for consumers, physicians, patients, and industry. Applications are underway in medicine and dermatology for the early detection, diagnosis, and targeted therapy of disease, and nanodesigned materials and devices are expected to be faster, smaller, more powerful, more efficient, and more versatile than their traditional counterparts. Written by experts working in this exciting field, Nanotechnology in Dermatology specifically addresses nanotechnology in consumer skin care products, in the diagnosis of skin disease, in the treatment of skin disease, and the overall safety of nanotechnology. The book also discusses future trends of this ever-growing and changing field, providing dermatologists, pharmaceutical companies, and consumer cosmetics companies with a clear understanding of the advantages and challenges of nanotechnology today.

Author : Lawrence S. Chan,M. Peter Marinkovich
Publisher : CRC Press
Page : 136 pages
File Size : 52,5 Mb
Release : 2021-08-01
Category : Medical
ISBN : 9781000460728

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New Technologies in Dermatological Science and Practice by Lawrence S. Chan,M. Peter Marinkovich Pdf

While science and technology have been moving at speed in the last decade and major investments have been placed in Artificial Intelligence, blockchain technology, 3D printing, and gene editing, medical practice, including cutaneous medicine (otherwise known as Dermatology), is only just starting to follow these technological advances. This book is a timely intellectual investment for cutaneous medicine, addressing these particularly needed areas. It is written for medical educators, dermatology residents, practicing dermatologists, and medical researchers in the area of skin diseases, to alert them all to medical advances and up-and-coming technology and in the hope, it will inspire further novel methodology for the future of cutaneous medicine, in diagnosis and therapy.

Author : Debmalya Barh
Publisher : Academic Press
Page : 292 pages
File Size : 45,6 Mb
Release : 2022-03-30
Category : Medical
ISBN : 9780323898782

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Biotechnology in Healthcare, Volume 1 by Debmalya Barh Pdf

Biotechnology in Healthcare, Technologies and Innovations, Volume One presents up-to-date knowledge on the emerging field of biotechnology as applied to the healthcare industry. Sections cover 3D printing, tissue engineering, synthetic biology, nano-biotechnology, omics, precision medicine, gene therapy, vaccine development, predictive healthcare, entrepreneurship, financing, business models, product development and marketing in the sector. This is a valuable source for biotechnologists, bioinformaticians, clinicians and members of biomedical and healthcare fields who need to understand more about the promising developments of the emerging field of biotechnology in healthcare. Presents the progress and innovations that biotechnology has accomplished in the field of healthcare Discusses the impact of healthcare biotechnology in global economics and business prospects Explains how biotechnology revolutionizes future healthcare approaches

Author : ConferenceSeries
Publisher : ConferenceSeries
Page : 79 pages
File Size : 50,7 Mb
Release : 2024-06-23
Category : Electronic
ISBN : 8210379456XXX

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Proceedings of 17th European Dermatology Congress 2017 by ConferenceSeries Pdf

March 1-3, 2018 Paris, France Key Topics : Melasma, Neutrophilic dermatosis, Onychomycosis, Overview of dermatitis, Pityriasis rosea, Scabies, Sunburn, Tinea versicolor, Hidradenitis suppurativa, Psoriasis, Vitiligo, Vulvar lichen planus, Allergy and Immunology, Infectious diseases, Genetic skin disease, Pediculosis capitis, Pediculosis corporis, Keloids, Skin Cancer, Beauty clinics and spa, Nutrition and Skin, Vitamin Disorders of Skin, Traditional Chinese Dermatology, Nanotechnology in Dermatology, Scope of Occupational Dermatology, Dermatology devices market growth, Region wise Dermatology market growth,

Author : Tony Burns,Stephen M. Breathnach,Neil Cox,Christopher Griffiths
Publisher : John Wiley & Sons
Page : 4193 pages
File Size : 46,6 Mb
Release : 2008-04-15
Category : Medical
ISBN : 9781405141048

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Rook's Textbook of Dermatology by Tony Burns,Stephen M. Breathnach,Neil Cox,Christopher Griffiths Pdf

The late Arthur Rook established the Textbook of Dermatologyas the most comprehensive work of reference available to thedermatologist and it enjoys instant name recognition. Eachsubsequent edition has been expanded as the subject has developedand the book remains the ultimate source of clinical informationfor the trainee and practising dermatologist alike. Rook's Textbook of Dermatology covers all aspects of skindisease from basic science through pathology and epidemiology toclinical practice. Long recognized for its unparalleled coverage ofdiagnosis, this clinical classic earned its reputation as adefinitive source of information. New features of this Seventh Edition include: Two new Editors, Neil Cox and Christopher Griffiths, join theteam Every chapter is updated and several are completely rewrittenfrom scratch Completely new chapter on AIDS and the Skin Traditional emphasis on diagnosis preserved More coverage of treatment in each of the disease-specificchapters

Author : ConferenceSeries
Publisher : ConferenceSeries
Page : 83 pages
File Size : 53,5 Mb
Release : 2024-06-23
Category : Electronic
ISBN : 8210379456XXX

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Proceedings of 13th Global Dermatologists Congress 2018 by ConferenceSeries Pdf

July 23-24, 2018 Moscow, Russia Key Topics : Aesthetic and Cosmetic Dermatology, Melanoma, Dermatological Diseases, Surgical Dermatology, Dermatological Oncology, Dermatology: Therapies and Advances, Hair and Nails, Alternative Medicine Solutions, Clinical and Medical Dermatology, Pediatric Dermatology, Hair transplantation, Dermatopathology, Cosmeceuticals, Psychodermatology, Veterinary Dermatology,