Genealogical Genetic Structure

Author : C. Cannings
Publisher : Cambridge University Press
Page : 172 pages
File Size : 48,9 Mb
Release : 1981-11-26
Category : Mathematics
ISBN : 052123946X

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Genealogical Genetic Structure by C. Cannings Pdf

Although the long-term processes of evolution are selection and mutation, the infrastructure of a population is a no less important force in determining the distributions of genetic characteristics observable within populations. In small populations, and in particular in human populations, complex patterns of genealogical relationship between individuals can be an important factor in the maintenance of genetic variability. The aim of this book is to develop the quantitative theory of the interrelationship between the genealogical and the genetic structures of a population. Aspects of other structural features, such as migration patterns, are also discussed, but are not central to the development. There are three major aspects; each comprises two chapters of the text. First, genealogical relationships are characterized in a way which can illuminate their genetic consequences. Second, the evolutionary aspects of genealogical structure are developed. Finally, the last two chapters present methods of characterizing the complete structure of a genealogy, and of computing relevant parameters of genealogical structure; these topics are of relevance to genetic epidemiology as well as to population genetics.

Author : Guanglin He,Mengge Wang,Ryan Lan-Hai Wei
Publisher : Frontiers Media SA
Page : 150 pages
File Size : 44,6 Mb
Release : 2023-02-03
Category : Science
ISBN : 9782832513675

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Forensic Investigative Genetic Genealogy and Fine-Scale Structure of Human Populations by Guanglin He,Mengge Wang,Ryan Lan-Hai Wei Pdf

Author : Chris Pomery
Publisher : Dundurn
Page : 178 pages
File Size : 55,9 Mb
Release : 2004-10-01
Category : Reference
ISBN : 9781459718234

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DNA and Family History by Chris Pomery Pdf

In the wake of highly-publicized scientific breakthroughs using genetics to confirm family connections, genealogists saw potential for their own research. Many are finding that comparing the DNA signatures of individuals can reveal startling information on families, surnames and origins.

Author : Jotun Hein,Mikkel Schierup,Carsten Wiuf
Publisher : Oxford University Press, USA
Page : 298 pages
File Size : 52,8 Mb
Release : 2004-12-09
Category : Population genetics
ISBN : 0191546151

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Gene Genealogies, Variation and Evolution: A primer in coalescent theory by Jotun Hein,Mikkel Schierup,Carsten Wiuf Pdf

Authored by leading experts, this seminal text presents a straightforward and elementary account of coalescent theory, which is a central concept in the study of genetic sequence variation observed in a population. Rich in examples and illustrations it is ideal for a graduate course in statistics, population, molecular and medical genetics, bioscience and medicine, and for students studying the evolution of human population and disease. It is also an invaluable reference for bioscientists and statisticians in the pharmaceutical industry and academia - ;Coalescent theory is a central concept in the study of genetic sequence variation that probabilistically describes the genealogy relating the sampled sequences. In this text, besides fulfilling the glaring need for such a book, the authors present this theory in a straightforward and elementary manner and describe the statistical and computational methods used in modelling and analyzing genetic sequence variation. Rich in examples and illustrations the book covers basic concepts, complications arising from geographical structure and recombination before considering aspects of statistical inference based on these models. The book ends with chapters on Gene Mapping, which combines sequence variation data with phenotypic data (such as disease) to define areas of the genome where genes are responsible for the trait, and Human Evolution, a research area that is experiencing a renaissance due to the enormous amounts of data produced in molecular studies. Authored by leading experts, this seminal text presents a straightforward and elementary account of coalescent theory, which is a central concept in the study of genetic sequence variation observed in a population. It is highly suitable for a graduate course in statistics, population, molecular and medical genetics, bioscience and medicine and students studying the evolution of human population and disease, and will be an invaluable reference for bioscientists and statisticians in the pharmaceutical industry and academia - ;an excellent and timely book that should appeal to a variety of people in genetics and applied mathematics. - Professor Montgomery Slatkin (Berkeley);the authors are outstanding experts in the field, and the book is topical and timely. - Professor David Balding (Imperial College);Hein, Schierup and Wiuf have written the first general book on the coalescent. It is an engaging combination of clear mathematical derivation and real data examples. - Professor Joe Felsenstein (University of Washington)

Author : Eviatar Zerubavel
Publisher : Oxford University Press
Page : 240 pages
File Size : 53,8 Mb
Release : 2011-11-04
Category : Social Science
ISBN : 9780199912315

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Ancestors and Relatives by Eviatar Zerubavel Pdf

Genealogy has long been one of humanity's greatest obsessions. But with the rise of genetics, and increasing media attention to it through programs like Who Do You Think You Are? and Faces of America, we are now told that genetic markers can definitively tell us who we are and where we came from. The problem, writes Eviatar Zerubavel, is that biology does not provide us with the full picture. After all, he asks, why do we consider Barack Obama black even though his mother was white? Why did the Nazis believe that unions of Germans and Jews would produce Jews rather than Germans? In this provocative book, he offers a fresh understanding of relatedness, showing that its social logic sometimes overrides the biological reality it supposedly reflects. In fact, rather than just biological facts, social traditions of remembering and classifying shape the way we trace our ancestors, identify our relatives, and delineate families, ethnic groups, nations, and species. Furthermore, genealogies are more than mere records of history. Drawing on a wide range of evidence, Zerubavel introduces such concepts as braiding, clipping, pasting, lumping, splitting, stretching, and pruning to shed light on how we manipulate genealogies to accommodate personal and collective agendas of inclusion and exclusion. Rather than simply find out who our ancestors were and identify our relatives, we actually construct the genealogical narratives that make them our ancestors and relatives. An eye-opening re-examination of our very notion of relatedness, Ancestors and Relatives offers a new way of understanding family, ethnicity, nationhood, race, and humanity.

Author : Blaine Bettinger
Publisher : Penguin
Page : 274 pages
File Size : 50,5 Mb
Release : 2019-08-13
Category : Reference
ISBN : 9781440300585

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The Family Tree Guide to DNA Testing and Genetic Genealogy by Blaine Bettinger Pdf

Unlock the family secrets in your DNA! Discover the answers to your family history mysteries using the most cutting edge tool available. This plain-English guide (newly updated and expanded to include th latest DNA developments) will teach you what DNA tests are available; the pros and cons of the major testing companies; and how to choose the right test to answer your specific genealogy questions. And once you've taken a DNA test, this guide will help you use your often-overwhelming results, with tips for understanding ethnicity estimates, navigating suggested cousin matches, and using third-party tools like GEDmatch to further analyze your data. The book features: · Colorful diagrams and expert definitions that explain key DNA terms and concepts such as haplogroups and DNA inheritance patterns · Detailed guides to each of the major kinds of DNA tests and tips for selecting the DNA test that can best help you solve your family mysteries, with case studies showing how each can be useful · Information about third-party tools you can use to more thoroughly analyze your test results once you've received them · Test comparison guides and research forms to help you select the most appropriate DNA test and organize your results · Insights into how adoptees and others who know little about their ancestry can benefit from DNA testing Whether you've just heard of DNA testing or you've tested at all three major companies, this guide will give you the tools you need to unpuzzle your DNA and discover what it can tell you about your family tree.

Author : Emily D. Aulicino
Publisher : Author House
Page : 263 pages
File Size : 44,8 Mb
Release : 2013-12-19
Category : Science
ISBN : 9781491840894

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Genetic Genealogy by Emily D. Aulicino Pdf

Finally, in the rapidly evolving field of genetic genealogy an up-to-date resource is here! A Genetic Genealogy Handbook: The Basics and Beyond provides genealogists with the knowledge and confidence to use DNA testing for family research. The book guides genealogists in understanding various tests and determining what DNA segments came from which ancestor. The book explains how DNA testing helps when written records stop and discusses how testing proves or disprove oral family history. Learn which tests help adoptees; understand why you resemble your relatives and how testing can connect you with cousins you never knew. Discover how to encourage potential cousins to test and learn guidelines for becoming a project administrator, genetic genealogy speaker or facilitator for your genealogical societys DNA interest group. A Genetic Genealogy Handbook: The Basics and Beyond helps experienced and fledgling researchers become genetic genealogists able to use DNA testing to resolve genealogical roadblocks.

Author : Charles F. Kerchner (Jr.)
Publisher : Unknown
Page : 58 pages
File Size : 44,9 Mb
Release : 2004
Category : DNA
ISBN : 0917335015

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Genetic Genealogy DNA Testing Dictionary by Charles F. Kerchner (Jr.) Pdf

Definitions of words, terms, acronyms, and abbreviations used in the new field of Genetic Genealogy DNA Testing to aide traditional genealogical research. A great resource for beginners.

Author : Jada Benn Torres,Gabriel A. Torres Colón
Publisher : Routledge
Page : 109 pages
File Size : 53,9 Mb
Release : 2020-10-20
Category : Science
ISBN : 9781000204810

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Genetic Ancestry by Jada Benn Torres,Gabriel A. Torres Colón Pdf

Genetic Ancestry focuses on the scientific nature and limitations of genetic ancestry testing. Co-authored by a genetic anthropologist and a cultural anthropologist, it examines the social, historical, and cultural dimensions of how people interpret genetic ancestry data. Utilizing examples from popular culture around the world and case studies from the Caribbean, the chapters highlight how genetic technology can sometimes bolster racial thinking and serve as tool of resistance and social justice.

Author : Anne Hart M. a.,Anne Hart
Publisher : iUniverse
Page : 656 pages
File Size : 54,9 Mb
Release : 2004-04-22
Category : DNA.
ISBN : 9780595316847

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How to Interpret Family History and Ancestry DNA Test Results for Beginners by Anne Hart M. a.,Anne Hart Pdf

How many DNA testing companies will show you how to interpret DNA test results for family history or direct you to instructional materials after you have had your DNA tested? Choose a company based on previous customer satisfaction, and whether the company gives you choices of how many markers you want, various ethnic and geographic databases, and surname projects based on DNA-driven genealogy. Before you select a company to test your DNA, find out how many genetic markers will be tested. For the maternal line, 400 base pairs of sequences are the minimum. For the paternal line (men only) 37 markers are great, but 25 markers also should be useful. Some companies offer a 12-marker test for surname genealogy groups at a special price. Find out how long the turnaround time is for waiting to receive your results. What is the reputation of the company? Do they have a contract with a university lab or a private lab? Who does the testing and who is the chief geneticist at their laboratory? What research articles, if any, has that scientist written or what research studies on DNA have been performed by the person in charge of the DNA testing at the laboratory? Who owns the DNA business that contracts with the lab? How involved in genealogy-related DNA projects and databases or services is the owner?

Author : Sergio Pistoi
Publisher : Crux Publishing Ltd
Page : 230 pages
File Size : 50,5 Mb
Release : 2019-10-20
Category : Science
ISBN : 9781909979895

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DNA Nation by Sergio Pistoi Pdf

"An indispensable resource for understanding the complex world of over-the-counter genetic testing ... the impressive book explores territory that is both easy to understand and enlightening." --Kirkus Review "Highly important, life-changing and delightfully written...[Pistoi] is pulling the rug out from under many of our preconceptions...with continuous wit and humor. A book which indeed demands to be savored." --Paul Levinson, author of The Silk Code and The Plot to Save Socrates “DNA Nation is a highly readable, scientifically accurate, guide to the brave new world of consumer genetic testing. A must for anyone intrigued by ancestry, health, and the grand variety of humankind”. --Ricki Lewis, author of Human Genetics and The Forever Fix “An enjoyable foray into the medical, legal and ethical aspects of the ongoing genetic revolution…a fun and important read guided by one of the nation's most gifted science writers.” --Jacob M. Appel, author of Who Says You're Dead Millions of people have done it: with a few clicks and some spit, and at less than the cost of a fancy dinner, you can buy a reading of your DNA online. With this in hand, you can find out where you came from, trace relatives around the world and find new friends on a genetic social network. You can learn about your predisposition to disease, get a genetically tailored diet, understand the sports to which you or your children might be more suited, and even find a date. It’s the dawn of consumer genomics, where the progress of biology meets the power of the Internet and big data. But do these applications work? Can we really prevent diseases based on what we read in our DNA? What do scientists say? And do we really understand the implications? What happens if things go wrong and the data is misused or the trust abused? Sergio Pistoi, a journalist and a DNA scientist, investigated this brave new world first-hand by interrogating his own genes, and has provided a practical, informative and thought-provoking survival guide to home genetic testing. From medicine to food, from social networking to genealogy and advertising, this book will show you how the DNA revolution is beginning to have such a profound impact on our daily lives and privacy and why it will influence the choices we make. If you are interested in how social media meets cutting-edge science, and what it means for your life, or if you are considering buying a DNA test, then this is the book for you.

Author : Anne Hart
Publisher : iUniverse
Page : 262 pages
File Size : 47,8 Mb
Release : 2003
Category : DNA.
ISBN : 9780595283064

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The Beginner's Guide to Interpreting Ethnic DNA Origins for Family History by Anne Hart Pdf

Genealogists are now using molecular genealogy--comparing and matching people by matrilineal DNA lineages--mtDNA or patrilineal Y-chromosome ancestry and/or racial percentages tests. People interested in ancestry now look at genetic markers to trace the migrations of the human species. Here's how to trace your genealogy by DNA from your grandparents back 10,000 or more years. Anyone can be interested in DNA for ancestry research, but of interest to Jews from Eastern Europe is to see how different populations from a mosaic of communities reached their current locations. From who are you descended? What markers will shed light on your deepest ancestry? You can study DNA for medical reasons or to discover the geographic travels and dwelling places of some of your ancestors. How do Europeans in general fit into the great migrations of prehistory that took all to where they are today based on their genetic DNA markers and sequences? Where is the geographic center of their origin and the roots of all people? Specifically, how can you interpret your DNA test for family history as a beginner in researching ancestry and your own family history?

Author : Kristi Lew
Publisher : Enslow Publishing, LLC
Page : 82 pages
File Size : 42,9 Mb
Release : 2018-07-15
Category : Young Adult Nonfiction
ISBN : 9780766099487

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Genetic Ancestry Testing by Kristi Lew Pdf

Popular television shows, such as Finding Your Roots and Who Do You Think You Are?, have ignited a renewed passion for traditional genealogical research and thrown genetic ancestry testing into the spotlight. Once a tool only for historians and forensic scientists, DNA testing is now available directly to the consumer. Supporting the Next Generation Science Standards on heredity and inheritance of traits, this book uses simple language and detailed images and charts to explain how genetic ancestry testing is done, what it can, and cannot, reveal about a family tree, and the potential unintended consequences of being tested. Sidebars offer information about related topics, such as the Human Genome Project, mitochondrial Eve, and genetic genealogy careers.

Author : Stephen Shennan
Publisher : Routledge
Page : 371 pages
File Size : 47,6 Mb
Release : 2017-07-12
Category : Science
ISBN : 9781351507073

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Mapping Our Ancestors by Stephen Shennan Pdf

Much of what we are comes from our ancestors. Through cultural and biological inheritance mechanisms, our genetic composition, instructions for constructing artifacts, the structure and content of languages, and rules for behavior are passed from parents to children and from individual to individual. Mapping Our Ancestors demonstrates how various genealogical or "phylogenetic" methods can be used both to answer questions about human history and to build evolutionary explanations for the shape of history. Anthropologists are increasingly turning to quantitative phylogenetic methods. These methods depend on the transmission of information regardless of mode and as such are applicable to many anthropological questions. In this way, phylogenetic approaches have the potential for building bridges among the various subdisciplines of anthropology; an exciting prospect indeed. The structure of Mapping Our Ancestors reflects the editors' goal of developing a common understanding of the methods and conditions under which ancestral relations can be derived in a range of data classes of interest to anthropologists. Specifically, this volume explores the degree to which patterns of ancestry can be determined from artifactual, genetic, linguistic, and behavioral data and how processes such as selection, transmission, and geography impact the results of phylogenetic analyses. Mapping Our Ancestors provides a solid demonstration of the potential of phylogenetic methods for studying the evolutionary history of human populations using a variety of data sources and thus helps explain how cultural material, language, and biology came to be as they are.

Author : Catherine Nash
Publisher : U of Minnesota Press
Page : 318 pages
File Size : 43,6 Mb
Release : 2015-04-01
Category : Social Science
ISBN : 9781452941820

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Genetic Geographies by Catherine Nash Pdf

What might be wrong with genetic accounts of personal or shared ancestry and origins? Genetic studies are often presented as valuable ways of understanding where we come from and how people are related. In Genetic Geographies, Catherine Nash pursues their troubling implications for our perception of sexual and national, as well as racial, difference. Bringing an incisive geographical focus to bear on new genetic histories and genetic genealogy, Nash explores the making of ideas of genetic ancestry, indigeneity, and origins; the global human family; and national genetic heritage. In particular, she engages with the science, culture, and commerce of ancestry in the United States and the United Kingdom, including National Geographic’s Genographic Project and the People of the British Isles project. Tracing the tensions and contradictions between the emphasis on human genetic similarity and shared ancestry, and the attention given to distinctive patterns of relatedness and different ancestral origins, Nash challenges the assumption that the concepts of shared ancestry are necessarily progressive. She extends this scrutiny to claims about the “natural” differences between the sexes and the “nature” of reproduction in studies of the geography of human genetic variation. Through its focus on sex, nation, and race, and its novel spatial lens, Genetic Geographies provides a timely critical guide to what happens when genetic science maps relatedness.