Genetic And Biological Markers In Drug Abuse And Alcoholism

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NIDA Research Monograph

Author : Anonim
Publisher : Unknown
Page : 144 pages
File Size : 42,9 Mb
Release : 1976
Category : Drug abuse
ISBN : COLUMBIA:HR01751301

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NIDA Research Monograph by Anonim Pdf

The Genetics of Alcoholism

Author : Henri Begleiter,Benjamin Kissin
Publisher : Alcohol and Alcoholism
Page : 420 pages
File Size : 53,9 Mb
Release : 1995
Category : Alcoholism
ISBN : 0195088778

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The Genetics of Alcoholism by Henri Begleiter,Benjamin Kissin Pdf

This volume provides an in-depth look at the genetic influences that contribute to the development of alcoholism. Part I: Epidemiologic Studies contains five chapters that examine the various approaches employed in the study of the genetics of alcoholism. It provides a historical perspectiveand details all the essentials of this subject. Part II: Selective Breeding Studies highlights the results of research involving the selective breeding of rodents. This type of research has produced homogenous strains exhibiting specific behavioral responses considered significant in thedevelopment and maintenance of alcohol dependence. The studies presented in Part III: Phenotypic Studies investigate and analyze phenotypic markers that serve as correlates to the genotypic determinants of alcoholism. Through its broad scope, this volume provides for the first time a panoramic viewof the knowledge available on the hereditary influences of alcoholism.

Pharmacogenomics of Alcohol and Drugs of Abuse

Author : Amitava Dasgupta,Loralie J. Langman
Publisher : CRC Press
Page : 255 pages
File Size : 43,7 Mb
Release : 2012-04-23
Category : Medical
ISBN : 9781439856116

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Pharmacogenomics of Alcohol and Drugs of Abuse by Amitava Dasgupta,Loralie J. Langman Pdf

Pharmacogenomics is the basis of personalized medicine, which is said to be the medicine of the future. Understanding genetic variation in drug and alcohol response is vital for professionals working in rehabilitation programs. The same principles that are applicable for therapeutic drugs are also applicable for drugs of abuse. Pharmacogenomics can supplement traditional therapeutic drug monitoring, potentially predicting correct dosage before initiation of the drug therapy. Applying these principles to testing and treatment, Pharmacogenomics of Alcohol and Drugs of Abuse discusses the role of the clinical laboratory in the practice of personalized medicine. With contributions from a range of experts, the book presents the genetic aspects of alcohol metabolism and other drugs including marijuana, cocaine, and amphetamines. In addition to basic pharmacogenomic aspects, the book addresses slate and trait markers of drugs of abuse so readers can consider setting appropriate biomarker tests in their clinical laboratory.

Addiction Mechanisms, Phenomenology and Treatment

Author : W.W. Fleischhacker,D.J. Brooks
Publisher : Springer Science & Business Media
Page : 136 pages
File Size : 51,6 Mb
Release : 2003-09-04
Category : Medical
ISBN : 3211013156

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Addiction Mechanisms, Phenomenology and Treatment by W.W. Fleischhacker,D.J. Brooks Pdf

Substance-related disorders pose an increasing challenge not only to the field of psychiatry but also to public health. The rapid development of our society has also changed the face of substance use and abuse, both quantitatively and qualitatively. In this volume international experts present reviews of the latest research covering many areas ranging from neurobiology to psychological management, as well as different drugs, from alcohol to ecstasy.

Types of Alcoholics

Author : Thomas F. Babor,Thomas Babor
Publisher : Unknown
Page : 272 pages
File Size : 54,5 Mb
Release : 1994
Category : Medical
ISBN : UVA:X002452792

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Types of Alcoholics by Thomas F. Babor,Thomas Babor Pdf

This volume, containing 16 papers, explores recent research and current theory pertaining to alcoholic typologies, giving special emphasis to genetic suscepibility and biological markers of clinical subtypes. This treatment is timely in view of recent trends in genetic epidemiology, treatment matching, and biological markers for alcoholism. The papers present recent research findings, explore commonalities across diverse theoretical and methodological approaches, and consider implications for diagnosis and treatment.

The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes

Author : Michael S. Ritsner
Publisher : Springer Science & Business Media
Page : 233 pages
File Size : 51,6 Mb
Release : 2009-04-24
Category : Medical
ISBN : 9789048122981

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The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes by Michael S. Ritsner Pdf

Neuropsychiatric disorders such as schizophrenia, mood disorders, Alzheimer’s disease, epilepsy, alcoholism, substance abuse and others are one of the most debilitating illnesses worldwide characterizing by the complexity of the causes, and lacking the laboratory tests that may promote diagnostic and prognostic procedures. Recent advances in neuroscience, genomic, genetic, proteomic and metabolomic knowledge and technologies have opened the way to searching biomarkers and endophenotypes, which may offer powerful and exciting opportunity to understand the etiology and the underlying pathophysiological mechanisms of neuropsychiatric disorders. The challenge now is to translate these advances into meaningful diagnostic and therapeutic advances. This book offers a broad synthesis of the current knowledge about diverse topics of the biomarker and endophenotype strategies in neuropsychiatry. The book is organized into four interconnected volumes: “Neuropsychological Endophenotypes and Biomarkers” (with overview of methodological issues of the biomarker and endophenotype approaches in neuropsychiatry and some technological advances), “Neuroanatomical and Neuroimaging Endophenotypes and Biomarkers”, “Metabolic and Peripheral Biomarkers” and “Molecular Genetic and Genomic Markers”. The contributors are internationally and nationally recognized researchers and experts from 16 countries. This four-volume handbook is intended for a broad spectrum of readers including neuroscientists, psychiatrists, neurologists, endocrinologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, health care providers in the field of neurology and mental health interested in trends that have crystallized in the last decade, and trends that can be expected to further evolve in the coming years. It is hoped that this book will also be a useful resource for the teaching of psychiatry, neurology, psychology and mental health.

Neuroimaging in Addiction

Author : Bryon Adinoff,Elliot A. Stein
Publisher : John Wiley & Sons
Page : 539 pages
File Size : 55,5 Mb
Release : 2011-11-02
Category : Medical
ISBN : 9781119972709

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Neuroimaging in Addiction by Bryon Adinoff,Elliot A. Stein Pdf

Neuroimaging in Addiction presents an up-to-date, comprehensive review of the functional and structural imaging human studies that have greatly advanced our understanding of this complex disorder. Approaching addiction from a conceptual rather than a substance-specific perspective, this book integrates broad neuropsychological constructs that consider addiction as a neuroplastic process with genetic, developmental, and substance-induced contributions. The internationally recognized contributors to this volume are leaders in clinical imaging with expertise that spans the addiction spectrum. Following a general introduction, an overview of neural circuitry and modern non-invasive imaging techniques provides the framework for subsequent chapters on reward salience, craving, stress, impulsivity and cognition. Additional topics include the use of neuroimaging for the assessment of acute drug effects, drug-induced neurotoxicity, non-substance addictive behaviors, and the application of imaging genetics to identify unique intermediate phenotypes. The book concludes with an exploration of the future promise for functional imaging as guide to the diagnosis and treatment of addictive disorders. Scientists and clinicians will find the material in this volume invaluable in their work towards understanding the addicted brain, with the overall goal of improved prevention and treatment outcomes for patients. Features a Foreword by Edythe London, Director of the Center for Addictive Behaviors, University of California at Los Angeles.

Alcohol and Its Biomarkers

Author : Amitava Dasgupta
Publisher : Elsevier
Page : 312 pages
File Size : 51,5 Mb
Release : 2015-02-18
Category : Science
ISBN : 9780128004098

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Alcohol and Its Biomarkers by Amitava Dasgupta Pdf

Alcohol and Its Biomarkers: Clinical Aspects and Laboratory Determination is a concise guide to all currently known alcohol biomarkers, their clinical application, and the laboratory methods used to detect them. Pathologists can use this resource to understand the limitations and cost factors associated with each method for determining certain alcohol biomarkers. In addition, interferences in these determinations are discussed, so that clinicians can understand the causes of falsely elevated biomarkers and pathologists and laboratory scientists can potentially eliminate them. The book focuses on the analytical methods used to detect alcohol in blood and urine, the limitations of alcohol determination using enzymatic methods, and the differences between clinical and forensic alcohol measurement. Chapters also cover cutting-edge alcohol biomarkers for potential use. Focuses on the analytical methods used for detecting alcohol in blood and urine along with the pitfalls and limitations of alcohol determination using enzymatic methods Explains the difference between clinical and forensic alcohol measurement Includes a brief overview of the benefits of consuming alcohol in moderation and the hazards of heavy drinking

Principles of Psychiatric Genetics

Author : John I. Nurnberger,Wade Berrettini
Publisher : Cambridge University Press
Page : 415 pages
File Size : 54,7 Mb
Release : 2012-09-13
Category : Medical
ISBN : 9780521896498

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Principles of Psychiatric Genetics by John I. Nurnberger,Wade Berrettini Pdf

A comprehensive, up-to-date resource providing information about genetic influences on disorders of behavior.

Cumulated Index Medicus

Author : Anonim
Publisher : Unknown
Page : 1836 pages
File Size : 43,8 Mb
Release : 2000
Category : Medicine
ISBN : OSU:32436010864898

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Cumulated Index Medicus by Anonim Pdf

Measuring Scholarly Impact

Author : Ying Ding,Ronald Rousseau,Dietmar Wolfram
Publisher : Springer
Page : 346 pages
File Size : 44,7 Mb
Release : 2014-11-06
Category : Computers
ISBN : 9783319103778

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Measuring Scholarly Impact by Ying Ding,Ronald Rousseau,Dietmar Wolfram Pdf

This book is an authoritative handbook of current topics, technologies and methodological approaches that may be used for the study of scholarly impact. The included methods cover a range of fields such as statistical sciences, scientific visualization, network analysis, text mining, and information retrieval. The techniques and tools enable researchers to investigate metric phenomena and to assess scholarly impact in new ways. Each chapter offers an introduction to the selected topic and outlines how the topic, technology or methodological approach may be applied to metrics-related research. Comprehensive and up-to-date, Measuring Scholarly Impact: Methods and Practice is designed for researchers and scholars interested in informetrics, scientometrics, and text mining. The hands-on perspective is also beneficial to advanced-level students in fields from computer science and statistics to information science.

A Research Agenda For DSM V

Author : David J. Kupfer,Michael B. First,Darrel A. Regier
Publisher : American Psychiatric Pub
Page : 336 pages
File Size : 41,5 Mb
Release : 2008-08-13
Category : Medical
ISBN : 9781585627721

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A Research Agenda For DSM V by David J. Kupfer,Michael B. First,Darrel A. Regier Pdf

In the ongoing quest to improve our psychiatric diagnostic system, we are now searching for new approaches to understanding the etiological and pathophysiological mechanisms that can improve the validity of our diagnoses and the consequent power of our preventive and treatment interventions -- venturing beyond the current DSM paradigm and DSM-IV framework. This thought-provoking volume -- produced as a partnership between the American Psychiatric Association, the National Institute of Mental Health, the National Institute on Alcohol Abuse and Alcoholism, and the National Institute on Drug Abuse -- represents a far-reaching attempt to stimulate research and discussion in the field in preparation for the eventual start of the DSM-V process, still several years hence. The book Explores a variety of basic nomenclature issues, including the desirability of rating the quality and quantity of information available to support the different disorders in the DSM in order to indicate the disparity of empirical support across the diagnostic system. Offers a neuroscience research agenda to guide development of a pathophysiologically based classification for DSM-V, which reviews genetic, brain imaging, postmortem, and animal model research and includes strategic insights for a new research agenda. Presents highlights of recent progress in developmental neuroscience, genetics, psychology, psychopathology, and epidemiology, using a bioecological perspective to focus on the first two decades of life, when rapid changes in behavior, emotion and cognition occur. Discusses how to address two important gaps in the current DSM-IV: (1) the categorical method of diagnosing personality disorders and their relationship with Axis I disorders, and (2) the limited provision for the diagnosis of relational disorders -- suggesting a research agenda for personality disorders that considers replacing the current categorical approach with a dimensional classification of personality. Reevaluates the relationship between mental disorders and disability, asserting that research into disability and impairment would benefit from the diagnosis of mental disorders be uncoupled from a requirement for impairment or disability to foster a more vigorous research agenda on the etiologies, courses, and treatment of mental disorders as well as disabilities and to avert unintended consequences of delayed diagnosis and treatment. Examines the importance of culture in psychopathology and the main cultural variables at play in the diagnostic process, stating that training present and future professionals in the need to include cultural factors in the diagnostic process is a logical step in any attempt to develop comprehensive research programs in psychology, psychiatry, and related disciplines. This fascinating work, with contributions from an international group of research investigators, reaches into the core of psychiatry, providing invaluable background and insights for all psychology and psychiatry professionals -- food for thought and further research that will be relevant for years to come.