Genetically Engineered Plants As A Source Of Vaccines Against Wide Spread Diseases

Author : Sergio Rosales-Mendoza
Publisher : Springer
Page : 295 pages
File Size : 45,9 Mb
Release : 2014-06-21
Category : Science
ISBN : 9781493908509

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Genetically Engineered Plants as a Source of Vaccines Against Wide Spread Diseases by Sergio Rosales-Mendoza Pdf

Genetically Engineered Plants as a Source of Vaccines Against Wide Spread Diseases: An Integrated View provides an integrated outlook of the disciplines involved in the development of plant-based vaccines as well as an updated compilation of the successful developments in the field. The volume covers immunological aspects of mucosal vaccine design, molecular approaches to attain high levels of the recombinant antigens, the rationale of using bioreactor to expand plant biomass, and pharmaceutical technology approaches that have been applied to the development of plant-based vaccine formulations. Practical figures and tables are presented to facilitate reading and identification of key points. Perspectives for this field are also discussed. Written by authorities in the field, Genetically Engineered Plants as a Source of Vaccines Against Wide Spread Diseases: An Integrated View is a comprehensive resource for researchers and students interested in plant genetics and breeding, immunology, and genetic engineering.

Author : Joseph E. Ciardi,Jerry R. McGhee,Jerry M. Keith
Publisher : Springer
Page : 0 pages
File Size : 53,9 Mb
Release : 2012-10-26
Category : Medical
ISBN : 1461365074

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Genetically Engineered Vaccines by Joseph E. Ciardi,Jerry R. McGhee,Jerry M. Keith Pdf

The National Institute of Dental Research sponsored a workshop on "Genetically Engineered Vaccines: Prospects for Oral Disease Prevention," held at the National Institutes of Health (NIH) on November 6-8, 1991. The purpose of the workshop was to convene molecular biologists and immunologists to address the state of the science in vaccine development and to explore the potential of developing vaccines for prevention of oral diseases. The goal was to elicit new research initiatives and recommendations for vaccine development with emphasis on the prevention of oral diseases and diseases affecting the orofacial tissues. The workshop was attended by more than 100 persons who heard 30 presentations, and the speakers provided the papers for this volume. The workshop focused on the following topics: oral diseases and host immune responses, update on vaccines and vaccine development, vaccines and the mucosal immune system, optimizing mucosal and systemic immune responses, delivery systems and immune analysis, target antigen selection and vaccine development, immunological correlates of protection and future direc tions/recommendations. Three key areas were identified: Optimizing the Mucosal Immune Response, Antigen Delivery Systems, and Target Antigens and Immunological Correlates of Protection. The summary and recommendations from these deliberations is included at the end of this volume.

Author : B. N. Prasad
Publisher : Unknown
Page : 256 pages
File Size : 51,6 Mb
Release : 1992
Category : Science
ISBN : UCAL:B3877050

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Role of Biotechnology in Agriculture by B. N. Prasad Pdf

In the context of South Asian Association for Regional Cooperation countries.

Author : Indu Ravi,Mamta Baunthiyal,Jyoti Saxena
Publisher : Springer Science & Business Media
Page : 264 pages
File Size : 41,5 Mb
Release : 2013-10-21
Category : Science
ISBN : 9788132215547

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Advances in Biotechnology by Indu Ravi,Mamta Baunthiyal,Jyoti Saxena Pdf

The book “Advances in Biotechnology” is about recent advances in some of the important fields that are ongoing in certain biotechnological applications. Biotechnology has been quite helpful in keeping pace with the demands of every increasing human population and in improving the quality of human life. Major biotechnological achievements associated with human welfare have been from the fields like genetic engineering; transgenic plants and animals; genomics, proteomics, monoclonal antibodies for the diagnosis of disease, gene therapy etc. Fourteen authoritative chapters written by experts having experience in academics and research on current developments and future trends in biotechnology have been empathized. The book provides a detailed account of various methodologies used in biotechnology i.e. High capacity vectors, DNA sequencing dealing with next generation sequencing, Molecular markers, DNA microarray technology, as well as Proteomics that have revolutionized biotechnology with a wide array of applications. The book not only presents a well-founded explanation of the topics but also aims to present up-to-date reviews of current research efforts, some thoughtful discussions on the potential benefits and risks involved in producing biotechnological products and the challenges of bringing such products to market. It will prove to be an excellent reference work for both academicians and researchers, indicating new starting points to young researchers for new projects in the field. The book is intended for biotechnologist, biologist, researchers, teachers and students of Biosciences and Biotechnology.

Author : Abdullah Makhzoum,Kathleen Hefferon
Publisher : CRC Press
Page : 482 pages
File Size : 48,7 Mb
Release : 2022-12-23
Category : Science
ISBN : 9781000818406

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Applications in Plant Biotechnology by Abdullah Makhzoum,Kathleen Hefferon Pdf

The book focuses on interesting topics in plant biotechnology and its applications. The first section covers a number of specific medicinal plants and their secondary metabolites using genetic and metabolic engineering. The pharmaceutical uses of these plant bioactive compounds and their applications in treating a variety of diseases including cancer, as well as recent works on in silico and bioinformatic analysis are described. The second section deals with innovative plant molecular pharming approaches and reviews the potential for using various plant host systems to design and produce effective new drugs to treat different illnesses and diseases such as HIV, infectious diseases, and other human and livestock diseases.

Author : D.N. Bharadwaj
Publisher : CRC Press
Page : 700 pages
File Size : 41,7 Mb
Release : 2018-10-29
Category : Science
ISBN : 9781351358477

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Advanced Molecular Plant Breeding by D.N. Bharadwaj Pdf

This new volume provides a better understanding of molecular plant breeding in order to boost the quality of agriculture produce, to increase crop yields and to provide nutritious food for everyone by 2050. Scientists believe the challenge can be met by implementing new and improved techniques of quantitative trait inheritance in plant breeding. Integrating genomics and molecular biology into appropriate tools and methodologies can help to create genetically engineered plants, such as by using biotic and abiotic stress tolerance, molecular markers, ‘-omics’ technology, and genome editing.

Author : National Research Council,Institute of Medicine,Board on Agriculture and Natural Resources,Food and Nutrition Board,Board on Life Sciences,Committee on Identifying and Assessing Unintended Effects of Genetically Engineered Foods on Human Health
Publisher : National Academies Press
Page : 254 pages
File Size : 51,5 Mb
Release : 2004-07-08
Category : Science
ISBN : 9780309166157

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Safety of Genetically Engineered Foods by National Research Council,Institute of Medicine,Board on Agriculture and Natural Resources,Food and Nutrition Board,Board on Life Sciences,Committee on Identifying and Assessing Unintended Effects of Genetically Engineered Foods on Human Health Pdf

Assists policymakers in evaluating the appropriate scientific methods for detecting unintended changes in food and assessing the potential for adverse health effects from genetically modified products. In this book, the committee recommended that greater scrutiny should be given to foods containing new compounds or unusual amounts of naturally occurring substances, regardless of the method used to create them. The book offers a framework to guide federal agencies in selecting the route of safety assessment. It identifies and recommends several pre- and post-market approaches to guide the assessment of unintended compositional changes that could result from genetically modified foods and research avenues to fill the knowledge gaps.

Author : Muhammad Sarwar Khan
Publisher : Bentham Science Publishers
Page : 413 pages
File Size : 44,5 Mb
Release : 2021-12-09
Category : Science
ISBN : 9789815036671

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Frontiers in Molecular Pharming by Muhammad Sarwar Khan Pdf

The advent of large-scale production and clinical trials of drugs developed through diverse production routes - involving viruses, microbes, plants, and animals - has increased the demand for an expanded capacity for pharmaceutical manufacturing. The production and purification of expressed proteins accounts for the bulk of the manufacturing costs for new therapeutics. Several pharmaceutical proteins have been synthesized by exploiting plant genetics allowing producers to override conventional approaches used to manufacture pharmaceuticals. The process of inserting a gene into a host organism for the purpose of harvesting a bioactive molecule for therapeutic use is known as molecular pharming. Frontiers in Molecular Pharming covers an array of topics relevant to understanding the structure, function, regulation, and mechanisms of action, biochemical significance, and usage of proteins and peptides as biomarkers, therapeutics, and vaccines for animals and humans. The contributions aim to highlight current progress in three areas, including system biology (in vivo characterization of proteins and peptides), molecular pharming for animals and molecular pharming for humans. The book gives special attention to computational biology tools, production platforms and fields (such as immunoinformatics) and applications of molecular pharming (such as veterinary therapeutics). A balance of theoretical concepts and practical applications is provided through 13 chapters. Frontiers in Molecular Pharming is an invaluable resource for students and researchers of biochemistry, molecular biology, and biotechnology. The book also serves as a springboard for understanding the process of how discoveries in protein and peptide research and its applications are coming to fruition.

Author : Muhammad Zia-Ul-Haq,May Nasser Bin-Jumah,Sarah I. Alothman,Hanan A. Henidi
Publisher : Springer Nature
Page : 284 pages
File Size : 50,8 Mb
Release : 2021-03-29
Category : Medical
ISBN : 9783030679897

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Alternative Medicine Interventions for COVID-19 by Muhammad Zia-Ul-Haq,May Nasser Bin-Jumah,Sarah I. Alothman,Hanan A. Henidi Pdf

This research volume examines the available alternative, complementary, pharmaceutical and vaccine methods for treating, mitigating, or preventing COVID-19. Coverage includes traditional Chinese medicine, herbal remedies, nutraceutical/dietary options, and drug/vaccine therapies. All the methods discussed will be critically examined to provide readers with a full, unbiased overview that includes pros/cons of each method. While the nature of COVID-19 is still being studied, and new research and theories are being published daily, this book endeavors to provide readers with a comprehensive summary of current research on alternative and mainstream treatment and prevention methods.

Author : Jean F. Challacombe
Publisher : CRC Press
Page : 116 pages
File Size : 40,8 Mb
Release : 2021-07-14
Category : Medical
ISBN : 9781000260540

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Metabolic Pathway Engineering by Jean F. Challacombe Pdf

Metabolic systems engineering combines the tools and approaches of systems biology, synthetic biology, and evolutionary engineering. This book reviews studies on metabolism, from the earliest work of Lavoisier and Buchner to current cutting-edge research in metabolic systems engineering. This technology has been used in bioengineering applications to create high-performing microbes and plants that produce important chemicals, pharmaceuticals, crops, and other natural products. Current applications include optimizing metabolic pathways to enhance degradation of biomass for biofuel production and accelerated processing of environmental waste products and contaminants. The book includes examples to illustrate the applications of this technology in the optimization of metabolic pathways to create robust industrial strains as well as in the engineering of biological processes involving health and diseases of humans, animals, and plants. Written by a seasoned computational biologist with many years of experience in genomics, bioinformatics, and systems biology, this book will appeal to anyone interested in metabolic systems analysis and metabolic pathway engineering.

Author : Hiroshi Kiyono
Publisher : Elsevier
Page : 501 pages
File Size : 50,8 Mb
Release : 1996-10-23
Category : Medical
ISBN : 9780080537054

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Mucosal Vaccines by Hiroshi Kiyono Pdf

This comprehensive, authoritative treatise covers all aspects of mucosal vaccines including their development, mechanisms of action, molecular/cellular aspects, and practical applications. The contributing authors and editors of this one-of-a-kind book are very well known in their respective fields. Mucosal Vaccines is organized in a unique format in which basic, clinical, and practical aspects of the mucosal immune system for vaccine development are described and discussed. This project is endorsed by the Society for Mucosal Immunology. Provides the latest views on mucosal vaccines Applies basic principles to the development of new vaccines Links basic, clinical, and practical aspects of mucosal vaccines to different infectious diseases Unique and user-friendly organization

Author : Clarisa Beatriz Palatnik-de-Sousa,Irene da Silva Soares,Daniela Santoro Rosa
Publisher : Frontiers Media SA
Page : 284 pages
File Size : 44,6 Mb
Release : 2018-07-12
Category : Antigens
ISBN : 9782889455225

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Epitope Discovery and Synthetic Vaccine Design by Clarisa Beatriz Palatnik-de-Sousa,Irene da Silva Soares,Daniela Santoro Rosa Pdf

Author : Jacqueline MacDonald
Publisher : Springer
Page : 367 pages
File Size : 44,6 Mb
Release : 2018-07-03
Category : Medical
ISBN : 9783319901374

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Prospects of Plant-Based Vaccines in Veterinary Medicine by Jacqueline MacDonald Pdf

This book provides an in-depth explanation of the advantages and current limitations of recombinant plant-made vaccines for use in veterinary medicine, including for livestock, pets, and wild animals. Written by top scientists in the field, it discusses the background to and latest scientific advances in plant-made vaccines for the most commonly targeted veterinary infections. With the recent high-profile research into recombinant plant-made therapeutics for Ebola and Zika viruses, it is likely that the products will be commercialized and widely used in the future. Plant-made therapeutics have a variety of advantages over those made in traditional systems; however, their most fruitful application may be in veterinary medicine, due to less stringent regulations and a greater need for low-cost products.

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Global Health,Forum on Microbial Threats
Publisher : National Academies Press
Page : 397 pages
File Size : 43,5 Mb
Release : 2016-10-21
Category : Medical
ISBN : 9780309377591

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Global Health Impacts of Vector-Borne Diseases by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Global Health,Forum on Microbial Threats Pdf

Pathogens transmitted among humans, animals, or plants by insects and arthropod vectors have been responsible for significant morbidity and mortality throughout recorded history. Such vector-borne diseases â€" including malaria, dengue, yellow fever, and plague â€" together accounted for more human disease and death in the 17th through early 20th centuries than all other causes combined. Over the past three decades, previously controlled vector-borne diseases have resurged or reemerged in new geographic locations, and several newly identified pathogens and vectors have triggered disease outbreaks in plants and animals, including humans. Domestic and international capabilities to detect, identify, and effectively respond to vector-borne diseases are limited. Few vaccines have been developed against vector-borne pathogens. At the same time, drug resistance has developed in vector-borne pathogens while their vectors are increasingly resistant to insecticide controls. Furthermore, the ranks of scientists trained to conduct research in key fields including medical entomology, vector ecology, and tropical medicine have dwindled, threatening prospects for addressing vector-borne diseases now and in the future. In June 2007, as these circumstances became alarmingly apparent, the Forum on Microbial Threats hosted a workshop to explore the dynamic relationships among host, pathogen(s), vector(s), and ecosystems that characterize vector-borne diseases. Revisiting this topic in September 2014, the Forum organized a workshop to examine trends and patterns in the incidence and prevalence of vector-borne diseases in an increasingly interconnected and ecologically disturbed world, as well as recent developments to meet these dynamic threats. Participants examined the emergence and global movement of vector-borne diseases, research priorities for understanding their biology and ecology, and global preparedness for and progress toward their prevention, control, and mitigation. This report summarizes the presentations and discussions from the workshop.

Author : Muhammad Zaffar Hashmi
Publisher : Springer Nature
Page : 447 pages
File Size : 53,6 Mb
Release : 2024-07-01
Category : Electronic
ISBN : 9783031509896

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Recent Advances in Industrial Biochemistry by Muhammad Zaffar Hashmi Pdf