Genetics In The Madhouse

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Genetics in the Madhouse

Author : Theodore M. Porter
Publisher : Princeton University Press
Page : 462 pages
File Size : 46,5 Mb
Release : 2020-07-14
Category : History
ISBN : 9780691203232

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Genetics in the Madhouse by Theodore M. Porter Pdf

"In the early 1800s, a century before there was any concept of the gene, physicians in insane asylums began to record causes of madness in their admission books. Almost from the beginning, they pointed to heredity as the most important of these causes. As doctors and state officials steadily lost faith in the capacity of asylum care to stem the terrible increase of insanity, they began emphasizing the need to curb the reproduction of the insane. They became obsessed with identifying weak or tainted families and anticipating the outcomes of their marriages. Genetics in the Madhouse is the untold story of how the collection and sorting of hereditary data in mental hospitals, schools for 'feebleminded' children, and prisons gave rise to a new science of human heredity. In this compelling book, Theodore Porter draws on untapped archival evidence from across Europe and North America to bring to light the hidden history behind modern genetics. He looks at the institutional use of pedigree charts, censuses of mental illness, medical-social surveys, and other data techniques--innovative quantitative practices that were worked out in the madhouse long before the manipulation of DNA became possible in the lab. Porter argues that asylum doctors developed many of the ideologies and methods of what would come to be known as eugenics, and deepens our appreciation of the moral issues at stake in data work conducted on the border of subjectivity and science. A bold rethinking of asylum work, Genetics in the Madhouse shows how heredity was a human science as well as a medical and biological one"--Jacket.

A Delicate Choreography

Author : David Sabean
Publisher : Walter de Gruyter GmbH & Co KG
Page : 1092 pages
File Size : 55,8 Mb
Release : 2023-10-23
Category : History
ISBN : 9783111014548

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A Delicate Choreography by David Sabean Pdf

The origins of the incest taboo have puzzled many of the most influential minds of the West, from Plutarch to St. Augustine, St. Thomas Aquinas, Martin Luther, David Hume, Lewis Henry Morgan, Sigmund Freud, Emile Durkheim, Edward Westermarck, and Claude Lévi-Strauss. This book puts the discussion of incest on a new foundation. It is the first attempt to thoroughly examine the rich literature, from philosophical, theological, and legal treatises to psychological and biological-genetic studies, to a wide variety of popular cultural media over a long period of time. The book offers a detailed examination of discursive and figurative representations of incest during five selected periods, from 1600 to the present. The incest discussion for each period is complemented with a presentation of dominant kinship structures and changes, without arguing for causal relations. Part I deals with the legacy of ecclesiastical marriage prohibitions of the Middle Ages: Historians dealing with the Reformation have wondered about the political and social implications of theological debates about the incest rules, the Enlightenment opted for sociological considerations of the household and a new anthropology based on the passions, Baroque discourse focused upon sexual relations among kin by marriage, while Enlightenment and Romantic discussions worried the intimacy of siblings. The first section of Part II deals with the six decades around 1900, during which European and American cultures obsessed about the sexuality of women. Almost everyone concurred in the idea that mother made the family what it was; that she configured the household, kept the lines of kinship vibrant, and stood at the threshold as stern gatekeeper, and many thought that she managed these tasks through her sexuality and an eroticized relationship with sons. Another story line, taken up in the section "Intermezzo," this one about the physical and mental consequences of inbreeding, appeared after 1850. To what extent do close-kin marriages pose risks for progeny? At its center, lay the incest problematic, now restated: Is avoidance of kin genetically programmed? Do all cultures know about risks of consanguinity? As for the twenty-first century, evolutionary and genetic assumptions are challenged by a living world population containing roughly one billion offspring of cousin marriages. Part III deals with one of the perhaps most remarkable reconfigurations of Western kinship in the aftermath of World War I: The shift from an endogamous to an exogamous alliance system centered on the "nuclear family." An historical anomaly, this family form began to dissolve almost as soon as it came together and, in the process, shifted the focus of incest concerns to a new pairing: father and daughter. By the 1970s, when the father/daughter problematic swept all other considerations of incest aside, that relationship had come to be modeled, for the most part, around power and its abusive potential. As for "incest," its representations in the last three decades of the twentieth century no longer focused on biologically damaged progeny but rather on power abuses in the nuclear family: sexual "abuse." By the mid-1990s, Western culture at least partly redirected its gaze away from father and daughter towards siblings, especially towards brothers and sisters and the sexual boundaries and erotics of their relationships. Correspondingly, siblings became a "model organism" for psychotherapy, evolutionary biology, and the science of genetics.

Madness and Genetic Determinism

Author : Patrick D. Hahn
Publisher : Springer
Page : 196 pages
File Size : 49,8 Mb
Release : 2019-07-11
Category : Psychology
ISBN : 9783030218669

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Madness and Genetic Determinism by Patrick D. Hahn Pdf

The book covers important topics in the psychiatric genetics (PG) field. Many of these have been overlooked in mainstream accounts, and many contemporary PG researchers have omitted or whitewashed the eugenic and “racial hygiene” origins of the field. The author critically analyzes PG evidence in support of genetic claims which, given the lack of gene discoveries, are based mainly on the results of psychiatric twin and adoption studies. Given that the evidence in favor of genetic influences is much weaker than mainstream sources report, due to serious issues in twin and adoption research, the author points to environmental factors, including trauma, as the main causes of conditions such as schizophrenia.

Heredity under the Microscope

Author : Soraya de Chadarevian
Publisher : University of Chicago Press
Page : 318 pages
File Size : 42,7 Mb
Release : 2020-07-02
Category : Science
ISBN : 9780226685250

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Heredity under the Microscope by Soraya de Chadarevian Pdf

By focusing on chromosomes, Heredity under the Microscope offers a new history of postwar human genetics. Today chromosomes are understood as macromolecular assemblies and are analyzed with a variety of molecular techniques. Yet for much of the twentieth century, researchers studied chromosomes by looking through a microscope. Unlike any other technique, chromosome analysis offered a direct glimpse of the complete human genome, opening up seemingly endless possibilities for observation and intervention. Critics, however, countered that visual evidence was not enough and pointed to the need to understand the molecular mechanisms. Telling this history in full for the first time, Soraya de Chadarevian argues that the often bewildering variety of observations made under the microscope were central to the study of human genetics. Making space for microscope-based practices alongside molecular approaches, de Chadarevian analyzes the close connections between genetics and an array of scientific, medical, ethical, legal, and policy concerns in the atomic age. By exploring the visual evidence provided by chromosome research in the context of postwar biology and medicine, Heredity under the Microscope sheds new light on the cultural history of the human genome.

Mobilizing Mutations

Author : Daniel Navon
Publisher : University of Chicago Press
Page : 409 pages
File Size : 51,8 Mb
Release : 2019-09-20
Category : Medical
ISBN : 9780226638096

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Mobilizing Mutations by Daniel Navon Pdf

With every passing year, more and more people learn that they or their young or unborn child carries a genetic mutation. But what does this mean for the way we understand a person? Today, genetic mutations are being used to diagnose novel conditions like the XYY, Fragile X, NGLY1 mutation, and 22q11.2 Deletion syndromes, carving out rich new categories of human disease and difference. Daniel Navon calls this form of categorization “genomic designation,” and in Mobilizing Mutations he shows how mutations, and the social factors that surround them, are reshaping human classification. Drawing on a wealth of fieldwork and historical material, Navon presents a sociological account of the ways genetic mutations have been mobilized and transformed in the sixty years since it became possible to see abnormal human genomes, providing a new vista onto the myriad ways contemporary genetic testing can transform people’s lives. Taking us inside these shifting worlds of research and advocacy over the last half century, Navon reveals the ways in which knowledge about genetic mutations can redefine what it means to be ill, different, and ultimately, human.

Blood Relations

Author : Jenny Bangham
Publisher : University of Chicago Press
Page : 353 pages
File Size : 42,5 Mb
Release : 2020-12-07
Category : Science
ISBN : 9780226740171

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Blood Relations by Jenny Bangham Pdf

Blood is messy, dangerous, and charged with meaning. By following it as it circulates through people and institutions, Jenny Bangham explores the intimate connections between the early infrastructures of blood transfusion and the development of human genetics. Focusing on mid-twentieth-century Britain, Blood Relations connects histories of eugenics to the local politics of giving blood, showing how the exchange of blood carved out networks that made human populations into objects of medical surveillance and scientific research. Bangham reveals how biology was transformed by two world wars, how scientists have worked to define racial categories, and how the practices and rhetoric of public health made genetics into a human science. Today, genetics is a powerful authority on human health and identity, and Blood Relations helps us understand how this authority was achieved.

Data Journeys in the Sciences

Author : Sabina Leonelli,Niccolò Tempini
Publisher : Springer Nature
Page : 411 pages
File Size : 42,8 Mb
Release : 2020-06-29
Category : Philosophy
ISBN : 9783030371777

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Data Journeys in the Sciences by Sabina Leonelli,Niccolò Tempini Pdf

This groundbreaking, open access volume analyses and compares data practices across several fields through the analysis of specific cases of data journeys. It brings together leading scholars in the philosophy, history and social studies of science to achieve two goals: tracking the travel of data across different spaces, times and domains of research practice; and documenting how such journeys affect the use of data as evidence and the knowledge being produced. The volume captures the opportunities, challenges and concerns involved in making data move from the sites in which they are originally produced to sites where they can be integrated with other data, analysed and re-used for a variety of purposes. The in-depth study of data journeys provides the necessary ground to examine disciplinary, geographical and historical differences and similarities in data management, processing and interpretation, thus identifying the key conditions of possibility for the widespread data sharing associated with Big and Open Data. The chapters are ordered in sections that broadly correspond to different stages of the journeys of data, from their generation to the legitimisation of their use for specific purposes. Additionally, the preface to the volume provides a variety of alternative “roadmaps” aimed to serve the different interests and entry points of readers; and the introduction provides a substantive overview of what data journeys can teach about the methods and epistemology of research.

Practical Realist Philosophy of Science

Author : Ave Mets,Endla Lõhkivi,Peeter Müürsepp,Jaana Eigi-Watkin
Publisher : Lexington Books
Page : 271 pages
File Size : 54,7 Mb
Release : 2024-05-15
Category : Philosophy
ISBN : 9781666937237

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Practical Realist Philosophy of Science by Ave Mets,Endla Lõhkivi,Peeter Müürsepp,Jaana Eigi-Watkin Pdf

Rein Vihalemm's philosophy of science left two prominent philosophical legacies: a methodological distinction of scientific disciplines and the practical realist philosophy of science. The diverse perspectives in this book explore some of the ideas that have sprung from Vihalemm's philosophy of science, and the applications of these approaches.

Social Mendelism

Author : Amir Teicher
Publisher : Cambridge University Press
Page : 283 pages
File Size : 48,8 Mb
Release : 2020-02-13
Category : Political Science
ISBN : 9781108499491

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Social Mendelism by Amir Teicher Pdf

Will revolutionize reader's understanding of the principles of modern genetics, Nazi racial policies and the relationship between them.

Disputed Inheritance

Author : Gregory Radick
Publisher : University of Chicago Press
Page : 643 pages
File Size : 43,5 Mb
Release : 2023-08-18
Category : Science
ISBN : 9780226822716

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Disputed Inheritance by Gregory Radick Pdf

A root-and-branch rethinking of how history has shaped the science of genetics. In 1900, almost no one had heard of Gregor Mendel. Ten years later, he was famous as the father of a new science of heredity—genetics. Even today, Mendelian ideas serve as a standard point of entry for learning about genes. The message students receive is plain: the twenty-first century owes an enlightened understanding of how biological inheritance really works to the persistence of an intellectual inheritance that traces back to Mendel’s garden. Disputed Inheritance turns that message on its head. As Gregory Radick shows, Mendelian ideas became foundational not because they match reality—little in nature behaves like Mendel’s peas—but because, in England in the early years of the twentieth century, a ferocious debate ended as it did. On one side was the Cambridge biologist William Bateson, who, in Mendel’s name, wanted biology and society reorganized around the recognition that heredity is destiny. On the other side was the Oxford biologist W. F. R. Weldon, who, admiring Mendel's discoveries in a limited way, thought Bateson's "Mendelism" represented a backward step, since it pushed growing knowledge of the modifying role of environments, internal and external, to the margins. Weldon's untimely death in 1906, before he could finish a book setting out his alternative vision, is, Radick suggests, what sealed the Mendelian victory. Bringing together extensive archival research with searching analyses of the nature of science and history, Disputed Inheritance challenges the way we think about genetics and its possibilities, past, present, and future.

Pennhurst and the Struggle for Disability Rights

Author : Dennis B. Downey,James W. Conroy
Publisher : Penn State Press
Page : 289 pages
File Size : 48,8 Mb
Release : 2020-04-13
Category : Social Science
ISBN : 9780271086385

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Pennhurst and the Struggle for Disability Rights by Dennis B. Downey,James W. Conroy Pdf

Conceived in the era of eugenics as a solution to what was termed the “problem of the feeble-minded,” state-operated institutions subjected people with intellectual and developmental disabilities to a life of compulsory incarceration. One of nearly 300 such facilities in the United States, Pennhurst State School and Hospital was initially hailed as a “model institution” but was later revealed to be a nightmare, where medical experimentation and physical and psychological abuse were rampant. At its peak, more than 3,500 residents were confined at Pennhurst, supervised by a staff of fewer than 600. Using a blended narrative of essays and first-person accounts, this history of Pennhurst examines the institution from its founding during an age of Progressive reform to its present-day exploitation as a controversial Halloween attraction. In doing so, it traces a decades-long battle to reform the abhorrent school and hospital and reveals its role as a catalyst for the disability rights movement. Beginning in the 1950s, parent-advocates, social workers, and attorneys joined forces to challenge the dehumanizing conditions at Pennhurst. Their groundbreaking advocacy, accelerated in 1968 by the explosive televised exposé Suffer the Little Children, laid the foundation for lawsuits that transformed American jurisprudence and ended mass institutionalization in the United States. As a result, Pennhurst became a symbolic force in the disability civil rights movement in America and around the world. Extensively researched and featuring the stories of survivors, parents, and advocates, this compelling history will appeal both to those with connections to Pennhurst and to anyone interested in the history of institutionalization and the disability rights movement.

The Politics of Making Kinship

Author : Erdmute Alber,David Warren Sabean,Simon Teuscher,Tatjana Thelen
Publisher : Berghahn Books
Page : 448 pages
File Size : 40,7 Mb
Release : 2022-12-09
Category : Political Science
ISBN : 9781800737853

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The Politics of Making Kinship by Erdmute Alber,David Warren Sabean,Simon Teuscher,Tatjana Thelen Pdf

The long tradition of Western political thought included kinship in models of public order, but the social sciences excised it from theories of the state, public sphere, and democratic order. Kinship has, however, neither completely disappeared from the political cultures of the West nor played the determining social and political role ascribed to it elsewhere. Exploring the issues that arise once the divide between kinship and politics is no longer taken for granted, The Politics of Making Kinship demonstrates how political processes have shaped concepts of kinship over time and, conversely, how political projects have been shaped by specific understandings, idioms and uses of kinship. Taking vantage points from the post-Roman era to early modernity, and from colonial imperialism to the fall of the Berlin Wall and beyond this international set of scholars place kinship centerstage and reintegrate it with political theory.

A Human Garden

Author : Paul-André Rosental
Publisher : Berghahn Books
Page : 248 pages
File Size : 41,6 Mb
Release : 2019-12-01
Category : History
ISBN : 9781789205442

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A Human Garden by Paul-André Rosental Pdf

Well into the 1980s, Strasbourg, France, was the site of a curious and little-noted experiment: Ungemach, a garden city dating back to the high days of eugenic experimentation that offered luxury living to couples who were deemed biologically fit and committed to contractual childbearing targets. Supported by public authorities, Ungemach aimed to accelerate human evolution by increasing procreation among eugenically selected parents. In this fascinating history, Paul-André Rosental gives an account of Ungemach’s origins and its perplexing longevity. He casts a troubling light on the influence that eugenics continues to exert—even decades after being discredited as a pseudoscience—in realms as diverse as developmental psychology, postwar policymaking, and liberal-democratic ideals of personal fulfilment.

Split and Splice

Author : Hans-Jörg Rheinberger
Publisher : University of Chicago Press
Page : 244 pages
File Size : 44,9 Mb
Release : 2023-04-21
Category : Science
ISBN : 9780226825311

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Split and Splice by Hans-Jörg Rheinberger Pdf

An esteemed historian of science explores the diversity of scientific experimentation. The experiment has long been seen as a test bed for theory, but in Split and Splice, Hans-Jörg Rheinberger makes the case, instead, for treating experimentation as a creative practice. His latest book provides an innovative look at the experimental protocols and connections that have made the life sciences so productive. Delving into the materiality of the experiment, the first part of the book assesses traces, models, grafting, and note-taking—the conditions that give experiments structure and make discovery possible. The second section widens its focus from micro-level laboratory processes to the temporal, spatial, and narrative links between experimental systems. Rheinberger narrates with accessible examples, most of which are drawn from molecular biology, including from the author’s laboratory notebooks from his years researching ribosomes. A critical hit when it was released in Germany, Split and Splice describes a method that involves irregular results and hit-or-miss connections—not analysis, not synthesis, but the splitting and splicing that form a scientific experiment. Building on Rheinberger’s earlier writing about science and epistemology, this book is a major achievement by one of today’s most influential theorists of scientific practice.

Born This Way

Author : Joanna Wuest
Publisher : University of Chicago Press
Page : 294 pages
File Size : 48,9 Mb
Release : 2023-09-15
Category : Political Science
ISBN : 9780226827537

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Born This Way by Joanna Wuest Pdf

"Across protests and courtrooms, LGBTQ activists argue that true sex or sexuality is encoded deep down, that it circulates in blood and is an expression of brain shapes and genetic codes. Their opponents incite panic over luring child groomers and a contagious "gender ideology" which corrupts the brains-and then bodies-of susceptible teenagers. In Born This Way: Science, Citizenship, and Inequality in the American LGBTQ Movement, Joanna Wuest tells the history of the LGBTQ rights movement, the modern scientific study of gender and sexuality, and the identity politics that formed at the nexus. She too reveals how conservative leaders have undermined science's ability to assist equal rights campaigns, reproductive rights, and climate change policies alike. Born This Way is at once a celebratory and cautionary tale, one which delineates a minority rights movement's impressive victories, its powerful and persuasive allies, and the ongoing assault on equality and science alike"--