Genome Mapping And Genomics In Human And Non Human Primates

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Genome Mapping and Genomics in Human and Non-Human Primates

Ravindranath Duggirala,Laura Almasy,Sarah Williams-Blangero,Solomon F.D. Paul,Chittaranjan Kole
Genome Mapping and Genomics in Human and Non Human Primates Book PDF

Author : Ravindranath Duggirala,Laura Almasy,Sarah Williams-Blangero,Solomon F.D. Paul,Chittaranjan Kole
Publisher : Springer
Page : 305 pages
File Size : 43,5 Mb
Release : 2015-03-25
Category : Science
ISBN : 9783662463062

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Genome Mapping and Genomics in Human and Non-Human Primates by Ravindranath Duggirala,Laura Almasy,Sarah Williams-Blangero,Solomon F.D. Paul,Chittaranjan Kole Pdf

This book provides an introduction to the latest gene mapping techniques and their applications in biomedical research and evolutionary biology. It especially highlights the advances made in large-scale genomic sequencing. Results of studies that illustrate how the new approaches have improved our understanding of the genetic basis of complex phenotypes including multifactorial diseases (e.g., cardiovascular disease, type 2 diabetes, and obesity), anatomic characteristics (e.g., the craniofacial complex), and neurological and behavioral phenotypes (e.g., human brain structure and nonhuman primate behavior) are presented. Topics covered include linkage and association methods, gene expression, copy number variation, next-generation sequencing, comparative genomics, population structure, and a discussion of the Human Genome Project. Further included are discussions of the use of statistical genetic and genetic epidemiologic techniques to decipher the genetic architecture of normal and disease-related complex phenotypes using data from both humans and non-human primates.

Monkeys, Apes, and Humans

Michael A. Huffman,Naofumi Nakagawa,Yasuhiro Go,Hiroo Imai,Masaki Tomonaga
Monkeys Apes and Humans Book PDF

Author : Michael A. Huffman,Naofumi Nakagawa,Yasuhiro Go,Hiroo Imai,Masaki Tomonaga
Publisher : Springer Science & Business Media
Page : 62 pages
File Size : 42,9 Mb
Release : 2012-10-20
Category : Medical
ISBN : 9784431541523

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Monkeys, Apes, and Humans by Michael A. Huffman,Naofumi Nakagawa,Yasuhiro Go,Hiroo Imai,Masaki Tomonaga Pdf

(tentative) What bring about biodiversity are not always genes. As is the case with humans, cultural diversity of non-human animals has also been found. Most of well-known examples of animal cultures are those of food acquisition behaviors, such as sweet-potato-washing by Japanese macaques and nut-cracking by chimpanzees. First author, Naofumi Nakagawa, introduces cultural diversity of social behaviors in wild Japanese macaques, such as the embracing behaviors between adult females in a wild group in each population of Yakushima, Kinkazan, and Shimokita. The subtle local difference in embracing can be identified as the first evidence for social customs in wild Japanese macaques. The next author, Michael A. Huffman, introduces the self-medicative behavior in non-human primates, which is a relatively new study in primatology. Parasites cause a variety of diseases that affect the behavior and reproductive fitness of an individual. He classifies health maintenance and self-medicative behaviors observed in non-human primates into four levels. Not only humans but also apes and monkeys are maintaining their health. The third authors, Hiroo Imai, Masaki Tomonaga, and Yasuhiro Go, are promoting comparative cognitive sciences of primates including human and chimpanzees. Recently, human personal genome projects progresses as related to the phenotypes including cognition, while there was no similar project for non-human primates. They started personal genome and transcriptome projects of chimpanzees in Primate Research Institute, Kyoto University, years ago. They introduce recent progresses of the project and related results based on the primate genome sciences.

Mapping and Sequencing the Human Genome

Committee on Mapping and Sequencing the Human Genome
Mapping and Sequencing the Human Genome Book PDF

Author : Committee on Mapping and Sequencing the Human Genome
Publisher : Unknown
Page : 132 pages
File Size : 52,8 Mb
Release : 1988
Category : Science
ISBN : NAP:13106

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Mapping and Sequencing the Human Genome by Committee on Mapping and Sequencing the Human Genome Pdf

Annotation Report of the Committee on [title]. Discusses the desirability and feasibility of a gigantic project. Annotation(c) 2003 Book News, Inc., Portland, OR (booknews.com).

Heritable Human Genome Editing

The Royal Society,National Academy of Sciences,National Academy of Medicine,International Commission on the Clinical Use of Human Germline Genome Editing
Heritable Human Genome Editing Book PDF

Author : The Royal Society,National Academy of Sciences,National Academy of Medicine,International Commission on the Clinical Use of Human Germline Genome Editing
Publisher : National Academies Press
Page : 239 pages
File Size : 50,6 Mb
Release : 2021-01-16
Category : Medical
ISBN : 9780309671132

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Heritable Human Genome Editing by The Royal Society,National Academy of Sciences,National Academy of Medicine,International Commission on the Clinical Use of Human Germline Genome Editing Pdf

Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.

Exploring Horizons for Domestic Animal Genomics

National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Board on Agriculture and Natural Resources,Kim Waddell,Robert Pool
Exploring Horizons for Domestic Animal Genomics Book PDF

Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Board on Agriculture and Natural Resources,Kim Waddell,Robert Pool
Publisher : National Academies Press
Page : 54 pages
File Size : 51,7 Mb
Release : 2002-08-27
Category : Science
ISBN : 9780309169127

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Exploring Horizons for Domestic Animal Genomics by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Board on Agriculture and Natural Resources,Kim Waddell,Robert Pool Pdf

Recognizing the important contributions that genomic analysis can make to agriculture, production and companion animal science, evolutionary biology, and human health with respect to the creation of models for genetic disorders, the National Academies convened a group of individuals to plan a public workshop that would: (1) assess these contributions; (2) identify potential research directions for existing genomics programs; and (3) highlight the opportunities of a coordinated, multi-species genomics effort for the science and policymaking communities. Their efforts culminated in a workshop sponsored by the U.S. Department of Agriculture, Department of Energy, National Science Foundation, and the National Institutes of Health. The workshop was convened on February 19, 2002. The goal of the workshop was to focus on domestic animal genomics and its integration with other genomics and functional genomics projects.

Genome Mapping and Genomics in Arthropods

Wayne Hunter,Chittaranjan Kole
Genome Mapping and Genomics in Arthropods Book PDF

Author : Wayne Hunter,Chittaranjan Kole
Publisher : Springer Science & Business Media
Page : 133 pages
File Size : 45,6 Mb
Release : 2007-12-10
Category : Science
ISBN : 9783540738336

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Genome Mapping and Genomics in Arthropods by Wayne Hunter,Chittaranjan Kole Pdf

The series "Genome Mapping and Genomics in Animals" provides comprehensive and up-to-date reviews on genomic research on a large variety of selected animal systems, contributed by leading scientists from around the world. The huge amount of information hitherto dispersed in journals is now available in this clearly structured reference work. Arthropods covered here include honeybee, bumblebee, the parasitic Jewel Wasp, silkworm, pea aphid, mosquito, Hessian fly and tick.

Genome Mapping and Genomics in Fishes and Aquatic Animals

Thomas D. Kocher,Chittaranjan Kole
Genome Mapping and Genomics in Fishes and Aquatic Animals Book PDF

Author : Thomas D. Kocher,Chittaranjan Kole
Publisher : Springer Science & Business Media
Page : 195 pages
File Size : 48,8 Mb
Release : 2008-06-07
Category : Science
ISBN : 9783540738374

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Genome Mapping and Genomics in Fishes and Aquatic Animals by Thomas D. Kocher,Chittaranjan Kole Pdf

Mapping of animal genomes has generated huge databases and several new concepts and strategies, which are useful to elucidate origin, evolution and phylogeny. Genetic and physical maps of genomes further provide precise details on chromosomal location, function, expression and regulation of academically and economically important genes. The series Genome Mapping and Genomics in Animals provides comprehensive and up-to-date reviews on genomic research on a large variety of selected animal systems, contributed by leading scientists from around the world. This volume summarizes the first era of genomic studies of aquaculture species, in which the tools and resources necessary to support whole-genome sequencing were developed. These tools will enhance efforts toward selective breeding of aquaculture species. Included in this volume are summaries of work on salmonids, cyprinids, catfish, tilapias, European sea bass, Japanese flounder, shrimps and oysters.

Chimpanzees in Biomedical and Behavioral Research

National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Institute of Medicine,Board on Health Sciences Policy,Committee on the Use of Chimpanzees in Biomedical and Behavioral Research
Chimpanzees in Biomedical and Behavioral Research Book PDF

Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Institute of Medicine,Board on Health Sciences Policy,Committee on the Use of Chimpanzees in Biomedical and Behavioral Research
Publisher : National Academies Press
Page : 200 pages
File Size : 52,9 Mb
Release : 2012-01-05
Category : Science
ISBN : 9780309220392

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Chimpanzees in Biomedical and Behavioral Research by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Institute of Medicine,Board on Health Sciences Policy,Committee on the Use of Chimpanzees in Biomedical and Behavioral Research Pdf

For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate research tools have rendered chimpanzees largely unnecessary as research subjects. The Institute of Medicine, in collaboration with the National Research Council, conducted an in-depth analysis of the scientific necessity for chimpanzees in NIH-funded biomedical and behavioral research. The committee concludes that while the chimpanzee has been a valuable animal model in the past, most current biomedical research use of chimpanzees is not necessary, though noted that it is impossible to predict whether research on emerging or new diseases may necessitate chimpanzees in the future.

Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research

National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Roundtable on Science and Welfare in Laboratory Animal Use
Care Use and Welfare of Marmosets as Animal Models for Gene Editing Based Biomedical Research Book PDF

Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Roundtable on Science and Welfare in Laboratory Animal Use
Publisher : National Academies Press
Page : 123 pages
File Size : 49,7 Mb
Release : 2019-08-26
Category : Science
ISBN : 9780309488518

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Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research by National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Roundtable on Science and Welfare in Laboratory Animal Use Pdf

The marmoset, a type of small monkey native to South America, is a research model of increasing importance for biomedical research in the United States and globally. Marmosets offer a range of advantages as animal models in neuroscience, aging, infectious diseases, and other fields of study. They may be particularly useful for the development of new disease models using genetic engineering and assisted reproductive technologies. However, concerns have been voiced with respect to the development of new marmoset-based models of disease, ethical considerations for their use, the supply of marmosets available for research, and gaps in guidance for their care and management. To explore and address these concerns, the Roundtable on Science and Welfare in Laboratory Animal Use hosted a public workshop on October 22-23, 2018, in Washington, DC. The workshop focused on the availability of marmosets in the United States and abroad; animal welfare and ethical considerations stemming from the use of wildtype and genetically modified marmosets; and standards of housing and care, dietary needs, and feeding requirements for marmosets in captivity. This publication summarizes the presentations and discussions from the workshop.

Genome Mapping and Genomics in Domestic Animals

Noelle E. Cockett,Chittaranjan Kole
Genome Mapping and Genomics in Domestic Animals Book PDF

Author : Noelle E. Cockett,Chittaranjan Kole
Publisher : Springer Science & Business Media
Page : 289 pages
File Size : 40,9 Mb
Release : 2008-10-31
Category : Science
ISBN : 9783540738350

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Genome Mapping and Genomics in Domestic Animals by Noelle E. Cockett,Chittaranjan Kole Pdf

Genomics research on animals has generated huge databases and several new concepts and strategies, which are used to elucidate origin, evolution and phylogeny of species. Genetic and physical maps of genomes give details on chromosomal location, function, expression and regulation of genes. The series Genome Mapping and Genomics in Animals provides comprehensive and up-to-date reviews on genomic research on selected animal systems contributed by leading scientists from around the world. This volume offers information on gene mapping and genomics research in domesticated and farmed animals including cattle, water buffalo, sheep, deer, poultry, turkeys, rabbits, dogs and pigs. While the genome maps for some species are very limited, full genome sequences are available for cattle, chickens and dogs. Genomic research contributes to the identification of genetic regions that control the functionality and well-being of animals. Several farmed species are also used as models for biomedical studies.

The SAGE Encyclopedia of Intellectual and Developmental Disorders

Ellen Braaten
The SAGE Encyclopedia of Intellectual and Developmental Disorders Book PDF

Author : Ellen Braaten
Publisher : SAGE Publications
Page : 4428 pages
File Size : 48,5 Mb
Release : 2018-01-29
Category : Psychology
ISBN : 9781506353296

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The SAGE Encyclopedia of Intellectual and Developmental Disorders by Ellen Braaten Pdf

According to the CDC “about one in six, or about 15%, of children aged 3 through 17 years have one or more developmental disabilities,” such as ADHD, autism spectrum disorders, cerebral palsy, intellectual disability, and learning disability. Intellectual disorders are characterized by significant limitations in both intellectual functioning and in adaptive behavior, which covers many everyday social and practical skills, impacting learning, reasoning, problem solving, and other cognitive processes. These disabilities originate before the age of 18 and continue across the life span. Developmental disorders are chronic disabilities that can be cognitive or physical or both. The disabilities appear before the age of 22 and are likely to progress across the lifespan. Some developmental disorders are largely physical issues, such as cerebral palsy or epilepsy. Some individuals may have a disorder that includes a physical and intellectual disability; for example, Down syndrome or fetal alcohol syndrome. Intellectual and developmental disorders are significant and growing issues that are studied across a number of disciplines. The SAGE Encyclopedia of Intellectual and Developmental Disorders is aimed at students interested in psychology, counseling, education, social work, psychiatry, health sciences, and more. This encyclopedia will provide an in-depth look at a wide range of disorders, alongside interventions, the latest research translated for an undergraduate audience, historical context, and assessment tools for higher-level students. We will take a truly interdisciplinary approach by also covering sociocultural viewpoints, policy implications, educational applications, ethical issues, and more.

Ancestors in Our Genome

Eugene E. Harris (Professor)
Ancestors in Our Genome Book PDF

Author : Eugene E. Harris (Professor)
Publisher : Oxford University Press, USA
Page : 249 pages
File Size : 46,5 Mb
Release : 2015
Category : Science
ISBN : 9780199978038

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Ancestors in Our Genome by Eugene E. Harris (Professor) Pdf

Geneticist Eugene Harris presents us with the complete and up-to-date account of the evolution of the human genome.

New Governance of Addictive Substances and Behaviours

Peter Anderson,Fleur Braddick,Patricia J. Conrod,Antoni Gual,Matilda Hellman,Silvia Matrai,David Miller,David Nutt,Jürgen Rehm,Jillian Reynolds,Tamyko Ysa
New Governance of Addictive Substances and Behaviours Book PDF

Author : Peter Anderson,Fleur Braddick,Patricia J. Conrod,Antoni Gual,Matilda Hellman,Silvia Matrai,David Miller,David Nutt,Jürgen Rehm,Jillian Reynolds,Tamyko Ysa
Publisher : Oxford University Press
Page : 252 pages
File Size : 47,8 Mb
Release : 2017-04-07
Category : Medical
ISBN : 9780191077968

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New Governance of Addictive Substances and Behaviours by Peter Anderson,Fleur Braddick,Patricia J. Conrod,Antoni Gual,Matilda Hellman,Silvia Matrai,David Miller,David Nutt,Jürgen Rehm,Jillian Reynolds,Tamyko Ysa Pdf

Addictions have increased markedly in contemporary societies over the past decades. As well as widely acknowledged issues surrounding illegal substance addictions, there are increasing numbers of problems related to behavioural addictions such as the use of legal substances such as antidepressants and amphetamines. These addictions are concerning for a range of public policy fields, not least, public health and social cohesion. As a result, cohesive governance of addictive substances and behaviours is paramount to future public policy. This book is based on the findings of a five year, multidisciplinary project (Addictions and Lifestyles in Contemporary Europe - Reframing Addictions Project) studying the pace and impact of addictions in Europe, and is the concluding volume in the Governance of Addictive Substances and Behaviours series. Authored by 11 leading figures in the fields of public health, psychology, sociology, psychiatry, addiction studies, epidemiology, and social and public policy, the book takes a truly comprehensive approach to the study of the current state of addiction governance in Europe and proposals for a future governance framework. No one country has yet got governance polices right. The project's outcome is a plan for the redesign of addictions governance, which includes amendments to key metrics used in research, promoting individual-level to society-level scope of understanding in policy approaches, and bringing the impact of dependency on societal well-being to the fore. New Governance of Addictive Substances and Behaviours is an unprecedented study, both in terms of international reach and scope of issues addressed. It will be a key resource for anyone with an interest in research-driven European policy change in public health and the field of addictive substances and behaviours.

Pharmacogenomics

Yui-Wing Francis Lam,Stuart R. Scott
Pharmacogenomics Book PDF

Author : Yui-Wing Francis Lam,Stuart R. Scott
Publisher : Academic Press
Page : 442 pages
File Size : 49,6 Mb
Release : 2018-11-27
Category : Medical
ISBN : 9780128126271

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Pharmacogenomics by Yui-Wing Francis Lam,Stuart R. Scott Pdf

Pharmacogenomics: Challenges and Opportunities in Therapeutic Implementation, Second Edition, provides comprehensive coverage of the challenges and opportunities facing the therapeutic implications of pharmacogenomics from academic, regulatory, pharmaceutical, socio-ethical and economic perspectives. While emphasis is on the limitations in moving the science into drug development and direct therapeutic applications, this book also focuses on clinical areas with successful applications and important initiatives that have the ability to further advance the discipline. New chapters cover important topics such as pharmacogenomic data technologies, clinical testing strategies, cost-effectiveness, and pharmacogenomic education and practice guidelines. The importance of ethnicity is also discussed, which highlights phar,acogenomic diversity across Latin American populations. With chapters written by interdisciplinary experts and insights into the future direction of the field, this book is an indispensable resource for academic and industry scientists, graduate students and clinicians engaged in pharmacogenomics research and therapeutic implementation. Provides viewpoints that focus on the scientific and translational challenges and opportunities associated with advancing the field of pharmacogenomics Highlights progress in both the research and clinical areas of pharmacogenomics, as well as relevant implementation experience, challenges, and perspectives on direct-to-consumer genetic testing Includes, where applicable, discussion points, review questions, and cases for self-assessment purposes and to facilitate in-depth discussion

Canadian Maternity and Pediatric Nursing

Jessica Webster,Caroline Sanders,Susan Ricci,Theresa Kyle,Susan Carmen
Canadian Maternity and Pediatric Nursing Book PDF

Author : Jessica Webster,Caroline Sanders,Susan Ricci,Theresa Kyle,Susan Carmen
Publisher : Lippincott Williams & Wilkins
Page : 3845 pages
File Size : 45,7 Mb
Release : 2019-08-14
Category : Medical
ISBN : 9781975102067

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Canadian Maternity and Pediatric Nursing by Jessica Webster,Caroline Sanders,Susan Ricci,Theresa Kyle,Susan Carmen Pdf

Canadian Maternity and Pediatric Nursing prepares your students for safe and effective maternity and pediatric nursing practice. The content provides the student with essential information to care for women and their families, to assist them to make the right choices safely, intelligently, and with confidence.