Glioblastoma Part Ii Molecular Targets And Clinical Trials An Issue Of

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Glioblastoma, Part II: Molecular Targets and Clinical Trials, An Issue of Neurosurgery Clinics of North America

Linda M. Liau

Author : Linda M. Liau
Publisher : Elsevier Health Sciences
Page : 208 pages
File Size : 40,9 Mb
Release : 2021-04-08
Category : Medical
ISBN : 9780323813068

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Glioblastoma, Part II: Molecular Targets and Clinical Trials, An Issue of Neurosurgery Clinics of North America by Linda M. Liau Pdf

This issue of Neurosurgery Clinics, guest edited by Dr. Linda M. Liau, is dedicated to Glioblastoma: Molecular and Clinical Trials. This issue is one of four selected each year by the series consulting editors, Drs. Russell R. Lonser and Daniel K. Resnick. Topics will include—but are not limited to—Pathology & Molecular Markers, Cellular States & Genetic Diversity in Glioblastoma, Mismatch Repair in Glioblastoma Resistance, Genetic Susceptibility in Brain Cancer, Pediatric Gliomas: Molecular Landscape & Emerging Targets, Molecularly Targeted Clinical Trials, Novel Radiation Sensitizers, Immunotherapy Checkpoint Inhibitors, Brain Tumor Vaccines, CAR T Cells, Oncolytic Virotherapy, Targeting Cancer Stem Cells, Therapeutic Delivery to CNS, Theranostics: Dual Modality PET Tracers, and Neuroimaging & Novel Response Assessments.

Modern Management of High Grade Glioma, Part II, An Issue of Neurosurgery Clinics - E-Book

Isaac Yang,Seunggu J. Han

Author : Isaac Yang,Seunggu J. Han
Publisher : Elsevier Health Sciences
Page : 240 pages
File Size : 47,8 Mb
Release : 2012-07-15
Category : Medical
ISBN : 9781455747689

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Modern Management of High Grade Glioma, Part II, An Issue of Neurosurgery Clinics - E-Book by Isaac Yang,Seunggu J. Han Pdf

Standard therapy for high grade glioma is a topic that is evolving, timely, and relevant. Guest Editors Isaac Yang, MD and Seunggu Han, MD have assembled a group of experts on management of high grade glioma. Some of the articles in this issue include: Use of language mapping to aid resection of eloquent gliomas; Clinical trials with immunotherapy; Clinical trials for small molecule inhibitors; Nanotechnology potential applications for GBM therapy; High Grade Gliomas in children; Modern Advances in Brain Tumor Treatments; Molecular pathways of Avastin interactions for the treatment of glioblastoma; and Quality of Life and Outcomes in Glioblastoma management.

Glioblastoma, Part I: Surgical Management and Adjuncts, An Issue of Neurosurgery Clinics of North America, E-Book

Michael A Vogelbaum

Author : Michael A Vogelbaum
Publisher : Elsevier Health Sciences
Page : 169 pages
File Size : 54,7 Mb
Release : 2020-12-04
Category : Medical
ISBN : 9780323790956

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Glioblastoma, Part I: Surgical Management and Adjuncts, An Issue of Neurosurgery Clinics of North America, E-Book by Michael A Vogelbaum Pdf

This issue of Neurosurgery Clinics, guest edited by Dr. Michael A. Vogelbaum, is devoted to Glioblastoma, Part I: Surgical Management and Adjuncts. This is one of four issues selected each year by the series Consulting Editors, Russell R. Lonser and Daniel K. Resnick. Articles in this issue include: Perioperative Management of Patients with Glioblastoma, Role of Resection in Glioblastoma Management, Advancing Imaging to Enhance Surgery, Intraoperative Imaging for High-Grade Glioma Surgery, Use of Intraoperative Fluorophores, Extent of Resection of Glioblastoma, Functional Mapping for Glioma Surgery: Preoperative Mapping Tools, Functional Mapping for Glioma Surgery: Intraoperative Mapping Tools, Surgical Adjuncts for Glioblastoma, Window of Opportunity Clinical Trials to Evaluate Novel Therapies for Brain Tumors, Stereotactic Laser Ablation of Glioblastoma, Radiosurgery for Glioblastoma, Challenges Associated with Reoperation in Patients with Glioma, and Surgery for Glioblastoma in Elderly Patients.

Low-Grade Glioma, An Issue of Neurosurgery Clinics of North America

Guy M. McKhann,Hugues Duffau

Author : Guy M. McKhann,Hugues Duffau
Publisher : Elsevier Health Sciences
Page : 128 pages
File Size : 55,5 Mb
Release : 2018-11-23
Category : Medical
ISBN : 9780323655026

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Low-Grade Glioma, An Issue of Neurosurgery Clinics of North America by Guy M. McKhann,Hugues Duffau Pdf

This issue of Neurosurgery Clinics, guest edited by Drs. Guy McKhann and Hugues Duffau, with consulting editors Russell R. Lonser and Daniel K. Resnick, will focus on Low-Grade Glioma. Topics includes, but are not limited to, Epidemiology and Molecular Epidemiology; WHO Pathological and Molecular Classification; Molecular Pathogenesis; Glioma Cell Migration and Heterogeneity; Clinical Presentation, Natural History, and Prognosis; LGG Epilepsy; MRI, fMRI, DTI, Molecular Imaging; Brain Mapping Techniques in LGG; Surgical Adjuncts to Increase EOR iMRI, Flourescence, Raman Histology; Mapping Cognition and Emotion; Extent of Resection; EOR vs Molecular Classification; Chemotherapy Treatment and Trials; Radiotherapy Treatment and Trials; Higher Order Surgical Questions; and Building a Glioma Practice.

Modern Management of High Grade Glioma, Part I, An Issue of Neurosurgery Clinics - E-Book

Isaac Yang,Seunggu J. Han

Author : Isaac Yang,Seunggu J. Han
Publisher : Elsevier Health Sciences
Page : 174 pages
File Size : 44,6 Mb
Release : 2012-04-28
Category : Medical
ISBN : 9781455744183

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Modern Management of High Grade Glioma, Part I, An Issue of Neurosurgery Clinics - E-Book by Isaac Yang,Seunggu J. Han Pdf

Standard therapy for high grade glioma is a topic that is evolving, timely, and relevant. Guest Editors Isaac Yang, MD and Seunggu Han, MD have assembled a group of experts to highlight the latest updates on various forms of management of high grade glioma. Some of the articles included in this issue focus on Extent of Resection for Glioblastoma; Role of adjuvant radiation therapy; Survival benefit of the Temozolomide protocol; Alternative chemotherapeutic agents; The role of avastin; Radiology; Pseuodprogression and Treatment effect; Pathology; Medical Management; Management of insular gliomas; Use of motor mapping; GBM treatment with clinical trials for surgical resection; Clinical trials with immunotherapy; Clinical trials for small molecule inhibitors; Future role of CED for GBM treatment; Application of a vault nanoparticle therapy for GBM therapy; Management of high grade gliomas in pediatric populations; Targeting Glioma Stem Like Cells with a focus on CD 133; and Potential Role for STAT3 inhibitors in glioblastoma.

Syndromic Neurosurgery, An Issue of Neurosurgery Clinics of North America , An Issue of Neurosurgery Clinics of North America, E-Book

James A. Stadler

Author : James A. Stadler
Publisher : Elsevier Health Sciences
Page : 169 pages
File Size : 49,7 Mb
Release : 2021-11-24
Category : Medical
ISBN : 9780323835336

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Syndromic Neurosurgery, An Issue of Neurosurgery Clinics of North America , An Issue of Neurosurgery Clinics of North America, E-Book by James A. Stadler Pdf

In this issue of Neurosurgery Clinics, Guest Editor James A. Stadler brings his considerable expertise to the topic of syndromic neurosurgery. Top experts in the field cover key topics such as Syndromic epilepsy, tumor syndromes, syndromic craniosynostosis, and more. Provides in-depth, clinical reviews on syndromic neurosurgery, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. Contains 14 relevant, practice-oriented topics including The history of syndromic neurosurgery; Multidisciplinary evaluation of neurosurgical patients with genetic syndromes; Neurosurgical evaluation and management of children with achondroplasia; Neurosurgical evaluation and management of patients with connective tissue disorders; and more.

Update on Motion Preservation Technologies, An Issue of Neurosurgery Clinics of North America, E-Book

Domagoj Coric

Author : Domagoj Coric
Publisher : Elsevier Health Sciences
Page : 129 pages
File Size : 49,9 Mb
Release : 2021-09-22
Category : Medical
ISBN : 9780323810555

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Update on Motion Preservation Technologies, An Issue of Neurosurgery Clinics of North America, E-Book by Domagoj Coric Pdf

This issue of Neurosurgery Clinics, guest edited by Dr. Domagoj Coric, provides an Update on Motion Preservation Technologies. This issue is one of four selected each year by our series consulting editors, Drs. Russell R. Lonser and Daniel K. Resnick. This issue discusses state-of-the-art indications, technique, devices, complications and evidence basis for motion preserving technologies in the cervical and lumbar spines. Topics covered in this issue will include: Cervical Total Disc Replacement: Indications and Technique, Cervical Total Disc Replacement: Off-label and Expanded Indications, Cervical Total Disc Replacement: FDA-approved Devices, Cervical Total Disc Replacement: Novel Devices, Cervical Spine Surgery: Arthroplasty versus Fusion versus Posterior Foraminotomy, Cervical Total Disc Replacement: Complications and Complication Avoidance, Cervical Total Disc Replacement: Long-term Outcomes, Biomechanics of Cervical Arthroplasty Devices, Adjacent-level Disease following Spinal Arthroplasty, Lumbar Total Disc Replacement: Current Usage, and Posterior Lumbar Facet Replacement and Arthroplasty.

Modern Management of High Grade Glioma, Part I, an Issue of Neurosurgery Clinics

Isaac Yang,Seunggu J. Han

Author : Isaac Yang,Seunggu J. Han
Publisher : Saunders
Page : 0 pages
File Size : 52,8 Mb
Release : 2012-04
Category : Medical
ISBN : 1455738972

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Modern Management of High Grade Glioma, Part I, an Issue of Neurosurgery Clinics by Isaac Yang,Seunggu J. Han Pdf

Standard therapy for high grade glioma is a topic that is evolving, timely, and relevant. Guest Editors Isaac Yang, MD and Seunggu Han, MD have assembled a group of experts to highlight the latest updates on various forms of management of high grade glioma. Some of the articles included in this issue focus on Extent of Resection for Glioblastoma; Role of adjuvant radiation therapy; Survival benefit of the Temozolomide protocol; Alternative chemotherapeutic agents; The role of avastin; Radiology; Pseuodprogression and Treatment effect; Pathology; Medical Management; Management of insular gliomas; Use of motor mapping; GBM treatment with clinical trials for surgical resection; Clinical trials with immunotherapy; Clinical trials for small molecule inhibitors; Future role of CED for GBM treatment; Application of a vault nanoparticle therapy for GBM therapy; Management of high grade gliomas in pediatric populations; Targeting Glioma Stem Like Cells with a focus on CD 133; and Potential Role for STAT3 inhibitors in glioblastoma.

Current State of the Art in Spinal Trauma, An Issue of Neurosurgery Clinics of North America, E-Book

John Hurlbert

Author : John Hurlbert
Publisher : Elsevier Health Sciences
Page : 137 pages
File Size : 40,8 Mb
Release : 2021-06-08
Category : Medical
ISBN : 9780323810593

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Current State of the Art in Spinal Trauma, An Issue of Neurosurgery Clinics of North America, E-Book by John Hurlbert Pdf

This issue of Neurosurgery Clinics, guest edited by Dr. John Hurlbert, is devoted to Current State of the Art in Spinal Cord Injury. This is one of four issues selected each year by the series Consulting Editors, Russell R. Lonser and Daniel K. Resnick. Articles in this issue are dedicated to basics of spinal cord injury and emerging therapy and include topics such as: Pathophysiology of spinal cord injury, Natural history of spinal cord injury, Diagnostic imaging in spinal cord injury, Spinal cord injury clinical assessment tools, Spinal cord injury management on the front line, Central Cord Syndrome redefined, Compartment Syndrome, Hypothermia, Pharmaceutical, Regeneration, and Neural interfacing and modulation.

Experimental Models in Glioblastoma Research

Felix Mircea Brehar,Mircea R. Gorgan

Author : Felix Mircea Brehar,Mircea R. Gorgan
Publisher : Nova Science Publishers
Page : 0 pages
File Size : 46,7 Mb
Release : 2015
Category : Cell culture
ISBN : 1633219240

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Experimental Models in Glioblastoma Research by Felix Mircea Brehar,Mircea R. Gorgan Pdf

This book covers the basic experimental models in glioblastoma research. It starts with a description in the first two chapters of general clinical, neuroimaging and genetic data about glioblastoma (WHO grade IV glioma), which is the most frequent and the most malignant primary tumour in adults. Despite the complex treatment which includes neurosurgery, radiotherapy and chemotherapy, survival of the patients usually is between 9 and 12 months. Moreover, the surgery is not able to cure the disease due to the specific infiltrative growth pattern of glioblastoma. Therefore, laboratory research is essential in order to find new molecular and cellular therapies for this lethal disease. After shortly reviewing the modern hypothesis regarding the origin of glioblastoma in the third chapter, namely the cancer stem cells hypothesis, the author describes step-by-step in the following chapters (Chapters 4-8) the most important in vitro and in vivo models of research in glioblastoma. Chapter 4 is dedicated to the first and the essential step in any research project on glioblastoma: how to obtain good quality glioblastoma samples, how to prepare the samples and how to store the samples long-term for subsequent research. Open surgery and the image-guided stereotactic technique are also described in this chapter. After obtaining the tumour samples, the next step is to initiate the primary cells cultures. These in vitro techniques (either serum conditioning cell cultures and tumour stem cells cultures) will be discussed in detail in Chapters 5 and 6. Usually the new molecules with antitumor activity are tested in vitro on both primary glioblastoma cells cultures but also on glioblastoma cells lines in order to obtain a better standardised results. The next chapter, Chapter 7 is dedicated to in vivo techniques, which are required for testing the anti-tumoural effect of the new molecules before starting with the clinical trials. The author describes in detail the techniques of stereotactic intracranial inoculation of glioblastoma cells (either glioblastoma cell lines or glioblastoma-derived tumour stem cells) and the main growth patterns of the intracranial glioblastoma xenografts obtained using these techniques. Another technique very useful for exploring in real time the migratory glioblastoma cells is the organotypic brain slice cultures which is described in the last chapter of the book.

Molecular Targets of CNS Tumors

Miklos Garami

Author : Miklos Garami
Publisher : BoD – Books on Demand
Page : 690 pages
File Size : 44,8 Mb
Release : 2011-09-22
Category : Medical
ISBN : 9789533077369

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Molecular Targets of CNS Tumors by Miklos Garami Pdf

Molecular Targets of CNS Tumors is a selected review of Central Nervous System (CNS) tumors with particular emphasis on signaling pathway of the most common CNS tumor types. To develop drugs which specifically attack the cancer cells requires an understanding of the distinct characteristics of those cells. Additional detailed information is provided on selected signal pathways in CNS tumors.

Immunotherapy, An Issue of Neurosurgery Clinics - E-Book

Isaac Yang,Michael J Lim

Author : Isaac Yang,Michael J Lim
Publisher : Elsevier Health Sciences
Page : 229 pages
File Size : 40,7 Mb
Release : 2010-01-05
Category : Medical
ISBN : 9781455700455

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Immunotherapy, An Issue of Neurosurgery Clinics - E-Book by Isaac Yang,Michael J Lim Pdf

For this issue, Dr. Michael Lim of Johns Hopkins and Dr. Isaac Yang of UCSF team up to deliver a packed issue on the latest developments in Immunotherapy. The issue covers hot topics such as immunostimulants, Passive Antibody Mediated Immunotherapy, Clinical Applications of A Peptide Based Vaccine, Challenges for Clinical Design of Immunotherapy Trials, The EGFRv3 Peptide Vaccine, Stem Cell Therapy and Dendritic Cell Vaccines, Dendritic Glioma Fusion Vaccine, Adoptive Cellular Immunotherapy, Virus Mediated Immunotherapy, and so much more.

Hemic and Immune Systems—Advances in Research and Application: 2012 Edition

Anonim

Author : Anonim
Publisher : ScholarlyEditions
Page : 422 pages
File Size : 41,8 Mb
Release : 2012-12-26
Category : Medical
ISBN : 9781464993763

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Hemic and Immune Systems—Advances in Research and Application: 2012 Edition by Anonim Pdf

Hemic and Immune Systems—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Hemic and Immune Systems. The editors have built Hemic and Immune Systems—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Hemic and Immune Systems in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Hemic and Immune Systems—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Issues in Neurology Research and Practice: 2011 Edition

Anonim

Author : Anonim
Publisher : ScholarlyEditions
Page : 5151 pages
File Size : 47,8 Mb
Release : 2012-01-09
Category : Medical
ISBN : 9781464963568

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Issues in Neurology Research and Practice: 2011 Edition by Anonim Pdf

Issues in Neurology Research and Practice / 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Neurology Research and Practice. The editors have built Issues in Neurology Research and Practice: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Neurology Research and Practice in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Neurology Research and Practice: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Advances in Cancer Research

Kenneth D. Tew,Paul B. Fisher

Author : Kenneth D. Tew,Paul B. Fisher
Publisher : Academic Press
Page : 426 pages
File Size : 48,7 Mb
Release : 2014-05-29
Category : Science
ISBN : 9780128003176

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Advances in Cancer Research by Kenneth D. Tew,Paul B. Fisher Pdf

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics. Provides information on cancer research Outstanding and original reviews Suitable for researchers and students

Glioblastoma Part Ii Molecular Targets And Clinical Trials An Issue Of Neurosurgery Clinics Of North America

Glioblastoma, Part II: Molecular Targets and Clinical Trials, An Issue of Neurosurgery Clinics of North America by Linda M. Liau Pdf

Modern Management of High Grade Glioma, Part II, An Issue of Neurosurgery Clinics - E-Book by Isaac Yang,Seunggu J. Han Pdf

Glioblastoma, Part I: Surgical Management and Adjuncts, An Issue of Neurosurgery Clinics of North America, E-Book by Michael A Vogelbaum Pdf

Low-Grade Glioma, An Issue of Neurosurgery Clinics of North America by Guy M. McKhann,Hugues Duffau Pdf

Modern Management of High Grade Glioma, Part I, An Issue of Neurosurgery Clinics - E-Book by Isaac Yang,Seunggu J. Han Pdf

Syndromic Neurosurgery, An Issue of Neurosurgery Clinics of North America , An Issue of Neurosurgery Clinics of North America, E-Book by James A. Stadler Pdf

Update on Motion Preservation Technologies, An Issue of Neurosurgery Clinics of North America, E-Book by Domagoj Coric Pdf

Modern Management of High Grade Glioma, Part I, an Issue of Neurosurgery Clinics by Isaac Yang,Seunggu J. Han Pdf

Current State of the Art in Spinal Trauma, An Issue of Neurosurgery Clinics of North America, E-Book by John Hurlbert Pdf

Experimental Models in Glioblastoma Research by Felix Mircea Brehar,Mircea R. Gorgan Pdf

Molecular Targets of CNS Tumors by Miklos Garami Pdf

Immunotherapy, An Issue of Neurosurgery Clinics - E-Book by Isaac Yang,Michael J Lim Pdf

Hemic and Immune Systems—Advances in Research and Application: 2012 Edition by Anonim Pdf

Issues in Neurology Research and Practice: 2011 Edition by Anonim Pdf

Advances in Cancer Research by Kenneth D. Tew,Paul B. Fisher Pdf

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