Glycobiology Of The Nervous System

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Glycobiology of the Nervous System

Robert K. Yu,Cara-Lynne Schengrund
Glycobiology of the Nervous System Book PDF

Author : Robert K. Yu,Cara-Lynne Schengrund
Publisher : Springer
Page : 590 pages
File Size : 43,5 Mb
Release : 2014-08-23
Category : Medical
ISBN : 9781493911547

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Glycobiology of the Nervous System by Robert K. Yu,Cara-Lynne Schengrund Pdf

A thorough introduction is provided to the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic information as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. The breadth and depth of topics covered make it an essential reference for those new to the field as well more seasoned investigators.

Neuroglycobiology

Minoru Fukuda,Urs Rutishauser,Ronald L. Schnaar
Neuroglycobiology Book PDF

Author : Minoru Fukuda,Urs Rutishauser,Ronald L. Schnaar
Publisher : Oxford University Press, USA
Page : 272 pages
File Size : 48,5 Mb
Release : 2005
Category : Language Arts & Disciplines
ISBN : 0198525389

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Neuroglycobiology by Minoru Fukuda,Urs Rutishauser,Ronald L. Schnaar Pdf

Carbohydrates play a major role in brain function. In the past decade, tremendous progress has been made in understanding their structure and function within the nervous system. This book presents a state of the art account of this rapidly expanding field.

Neuroglycobiology

Minoru Fukuda,Urs Rutishauser,Ronald L. Schnaar
Neuroglycobiology Book PDF

Author : Minoru Fukuda,Urs Rutishauser,Ronald L. Schnaar
Publisher : Unknown
Page : 229 pages
File Size : 47,5 Mb
Release : 2005
Category : Brain
ISBN : 0191723878

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Neuroglycobiology by Minoru Fukuda,Urs Rutishauser,Ronald L. Schnaar Pdf

Carbohydrates play a major role in brain function. In the past decade, tremendous progress has been made in understanding their structure and function within the nervous system. This book presents a state of the art account of this rapidly expanding field.

Glycobiology and the Brain

M. Nicolini,Paolo Zatta
Glycobiology and the Brain Book PDF

Author : M. Nicolini,Paolo Zatta
Publisher : Pergamon
Page : 314 pages
File Size : 55,8 Mb
Release : 1994
Category : Brain
ISBN : UOM:39015029112235

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Glycobiology and the Brain by M. Nicolini,Paolo Zatta Pdf

This book draws together for the first time contributions from carbohydrate research in the areas of neurobiology, neuropathology, and neuropharmacology, highlighting the importance of carbohydrates in the understanding of neurobiology, the development of neuropathology and the commercialisation of neuropharmacological agents. Glycobiology is a relatively new field emerging in importance both in research institutes and industry. The chapters in this book focus on aspects of the present and future application of the study of glycobiology to brain biochemistry, from basic research on glycoconjugates to practical identification of carbohydrates in neuropathological studies and the relevance of structural studies in a pharmacological perspective.

Essentials of Glycobiology

Ajit Varki,Maarten J. Chrispeels
Essentials of Glycobiology Book PDF

Author : Ajit Varki,Maarten J. Chrispeels
Publisher : CSHL Press
Page : 694 pages
File Size : 52,8 Mb
Release : 1999
Category : Medical
ISBN : 0879696818

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Essentials of Glycobiology by Ajit Varki,Maarten J. Chrispeels Pdf

Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

2019 PhotonIcs and Electromagnetics Research Symposium Spring (PIERS Spring)

IEEE Staff
2019 PhotonIcs and Electromagnetics Research Symposium Spring PIERS Spring Book PDF

Author : IEEE Staff
Publisher : Unknown
Page : 128 pages
File Size : 53,5 Mb
Release : 2019-06-17
Category : Electronic
ISBN : 1728134048

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2019 PhotonIcs and Electromagnetics Research Symposium Spring (PIERS Spring) by IEEE Staff Pdf

PIERS (PhotonIcs and Electromagnetics Research Symposium) provides an international forum for reporting progress and recent advances in the modern development of electromagnetics, photonics and exciting applications Topics include electromagnetic theory, photonics, quantum optics, plasmonics, metamaterials, antennas, microwave technologies, acoustics, computational electromagnetics, electromagnetic compatibility, scattering, remote sensing, radars, radiometry, imaging, radiative transfer, material effects, inverse problems and all other modern developments in electromagnetics and photonics PIERS 2019 Rome has the following five topic areas SC1 Computational Electromagnetics, Electromagnetic Compatibility, Scattering and Electromagnetic Theory SC2 Metamaterials, Plasmonics and Complex Media SC3 Optics and Photonics SC4 Antennas and Microwave Technologies SC5 Remote Sensing, Inverse Problems, Imaging, Radar and Sensing

Glycoconjugates

Howard J. Allen,Edward C. Kisailus
Glycoconjugates Book PDF

Author : Howard J. Allen,Edward C. Kisailus
Publisher : CRC Press
Page : 704 pages
File Size : 53,7 Mb
Release : 1992-04-15
Category : Medical
ISBN : 0824784316

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Glycoconjugates by Howard J. Allen,Edward C. Kisailus Pdf

Glycoconjugates Composition: Structure, and Function provides an excellent overview of the composition, biosynthesis, function and structure of the carbohydrate chains of glycoconjugates from higher organisms. It is recommended as a core reference text, providing excellent coverage of the glycoconjugate field.

Drug and Gene Delivery to the Central Nervous System for Neuroprotection

Hari S. Sharma,Dafin F. Muresanu,Aruna Sharma
Drug and Gene Delivery to the Central Nervous System for Neuroprotection Book PDF

Author : Hari S. Sharma,Dafin F. Muresanu,Aruna Sharma
Publisher : Springer
Page : 228 pages
File Size : 44,6 Mb
Release : 2017-06-05
Category : Medical
ISBN : 9783319576961

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Drug and Gene Delivery to the Central Nervous System for Neuroprotection by Hari S. Sharma,Dafin F. Muresanu,Aruna Sharma Pdf

This book summarizes the latest research on drug and gene delivery to the central nervous system (CNS). The chapters address safety concerns regarding the nanotechnology that is needed to develop nanomedicine for clinical practice. Particular focus is given to new technologies that have emerged in recent years to deliver therapeutic materials, such as genes, drugs, and other agents using nanotechnologies of diverse origin. This is an ideal book for students, teachers, researchers, and clinicians interested in a deeper understanding of nanotechnological advances in therapeutic medicine. This book also: Broadens readers’ understanding of viral vector gene delivery to the brain for treating neurogenetic diseases as well as targeted gene delivery into the brain using microbubble-facilitated focused ultrasound Covers in detail the latest developments in delivering therapeutic materials, such as siRNA delivery to the brain for treating neurological diseases, neuroprotective effects of gelatin nanoparticles in stroke, and nanowired drug delivery for brain diseases, heat stroke, and CNS injury Enriches understanding of new technologies for delivering therapeutic materials treating Alzheimer’s Disease, including targeted nanodrug delivery through the blood-brain barrier and the superior neuroprotective effects of nanowired drug delivery in Alzheimer’s Disease

The Sugar Code

Hans-Joachim Gabius
The Sugar Code Book PDF

Author : Hans-Joachim Gabius
Publisher : John Wiley & Sons
Page : 560 pages
File Size : 44,9 Mb
Release : 2011-09-19
Category : Science
ISBN : 9783527644940

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The Sugar Code by Hans-Joachim Gabius Pdf

A reader friendly overview of the structure and functional relevance of natural glycosylation and its cognate proteins (lectins), this book is also one of the few books to cover their role in health and disease. Edited by one of the pioneering experts in the field and written by a team of renowned researchers this resource is a perfect introduction for all students in life and medical sciences, biochemistry, chemistry and pharmacy. Website: WWW.WILEY-VCH.DE/HOME/THESUGARCODE

Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease

Shyamasree Ghosh
Sialic Acids and Sialoglycoconjugates in the Biology of Life Health and Disease Book PDF

Author : Shyamasree Ghosh
Publisher : Academic Press
Page : 386 pages
File Size : 45,8 Mb
Release : 2020-01-08
Category : Science
ISBN : 9780128161272

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Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease by Shyamasree Ghosh Pdf

Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease enables the reader to understand the role of sialylation as a post translational modification. The book provides insights on the latest knowledge in the field of sialoglycobiology. Sialic acids as terminal residues of oligosaccharide chains play crucial roles in several cellular recognition events. Synthesized post translationally, they play an important role in recognition, signaling, immunological response and cell-cell interaction. Improper sialylations have been associated with several diseases including cancer. In the post genomics and proteomics era, sialoglybiology has become more and more important in deciphering health and disease conditions. Discusses the sialic acids and their role in different diseases (other than cancer) Provides an understanding of sialylations as post translational modifications (PTM) Demonstrates the impact sialylation has on infectious diseases, the autoimmune system and health Gives insights on the importance of sialic acid biology through animal models

Handbook of Glycosyltransferases and Related Genes

Naoyuki Taniguchi,Koichi Honke,Minoru Fukuda
Handbook of Glycosyltransferases and Related Genes Book PDF

Author : Naoyuki Taniguchi,Koichi Honke,Minoru Fukuda
Publisher : Springer Science & Business Media
Page : 668 pages
File Size : 50,5 Mb
Release : 2011-06-28
Category : Science
ISBN : 9784431678779

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Handbook of Glycosyltransferases and Related Genes by Naoyuki Taniguchi,Koichi Honke,Minoru Fukuda Pdf

The so-called postgenomic research era has now been launched, and the field of gly cobiology and glycotechnology has become one of the most important areas in life science because glycosylation is the most common post-translational modification reaction of proteins in vivo. On the basis of Swiss-Prot data, over 50% proteins are known to undergo glycosylation, but in fact the actual functions of most of the sugar chains in the glycoconjugates remain unknown. The complex carbohydrate chains of glycoproteins, glycolipids, and proteoglycans represent the secondary gene products formed through the reactions of glycosyl transferases. The regulation of the biosynthesis of sugar chains is under the control of the expression of glycosyltransferases, their substrate specificity, and their local ization in specific tissue sites. There is a growing body of evidence to suggest that these enzymes play pivotal roles in a variety of important cellular differentiation and developmental events, as well as in disease processes. Over 300 glycosyltransferases appear to exist in mammalian tissues. If the genes that have been purified and cloned from various species such as humans, cattle, pigs, rats and mice are counted as one, approximately 110 glycogenes that encode glycosyltransferases and related genes have been cloned at present, and this number continues to grow each day. However, most of the functions of the glycosyltransferase genes and related genes are unknown. This fact has stimulated numerous new and interesting approaches in molecular biologi cal investigations.

The Art of Carbohydrate Analysis

Gerrit J. Gerwig
The Art of Carbohydrate Analysis Book PDF

Author : Gerrit J. Gerwig
Publisher : Springer Nature
Page : 362 pages
File Size : 49,7 Mb
Release : 2021-10-23
Category : Medical
ISBN : 9783030777913

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The Art of Carbohydrate Analysis by Gerrit J. Gerwig Pdf

The growing importance of glycobiology and carbohydrate chemistry in modern biotechnology and the pharmaceutical industry makes accurate carbohydrate analysis indispensable. This book provides the principles and protocols of various fundamental carbohydrate analysis methods. Choice of method is entirely dependent upon the type of material being investigated (biological samples, food products, etc.), and the level of structural detail required, i.e. sugar content, compositional analysis, linkages between the sugar components, or the total chemical structure of a given molecule. Full structural characterization of carbohydrate chains requires significant time, resources, and skill in several methods of analysis; no single technique can address all glycan analysis needs. This book summarizes several existing analytical techniques (both chemical and physical) in an introductory volume designed for the non-expert researcher or novice scientist. While background in carbohydrate chemistry is assumed, all information necessary to understanding the described techniques is addressed in the text.

Handbook of In Vivo Chemistry in Mice

Katsunori Tanaka,Kenward Vong
Handbook of In Vivo Chemistry in Mice Book PDF

Author : Katsunori Tanaka,Kenward Vong
Publisher : John Wiley & Sons
Page : 560 pages
File Size : 42,9 Mb
Release : 2020-04-27
Category : Science
ISBN : 9783527344321

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Handbook of In Vivo Chemistry in Mice by Katsunori Tanaka,Kenward Vong Pdf

Provides timely, comprehensive coverage of in vivo chemical reactions within live animals This handbook summarizes the interdisciplinary expertise of both chemists and biologists performing in vivo chemical reactions within live animals. By comparing and contrasting currently available chemical and biological techniques, it serves not just as a collection of the pioneering work done in animal-based studies, but also as a technical guide to help readers decide which tools are suitable and best for their experimental needs. The Handbook of In Vivo Chemistry in Mice: From Lab to Living System introduces readers to general information about live animal experiments and detection methods commonly used for these animal models. It focuses on chemistry-based techniques to develop selective in vivo targeting methodologies, as well as strategies for in vivo chemistry and drug release. Topics include: currently available mouse models; biocompatible fluorophores; radionuclides for radiodiagnosis/radiotherapy; live animal imaging techniques such as positron emission tomography (PET) imaging; magnetic resonance imaging (MRI); ultrasound imaging; hybrid imaging; biocompatible chemical reactions; ligand-directed nucleophilic substitution chemistry; biorthogonal prodrug release strategies; and various selective targeting strategies for live animals. -Completely covers current techniques of in vivo chemistry performed in live animals -Describes general information about commonly used live animal experiments and detection methods -Focuses on chemistry-based techniques to develop selective in vivo targeting methodologies, as well as strategies for in vivo chemistry and drug release -Places emphasis on material properties required for the development of appropriate compounds to be used for imaging and therapeutic purposes in preclinical applications Handbook of In Vivo Chemistry in Mice: From Lab to Living System will be of great interest to pharmaceutical chemists, life scientists, and organic chemists. It will also appeal to those working in the pharmaceutical and biotechnology industries.

Cell Surface Carbohydrates and Cell Development

Minoru Fukuda
Cell Surface Carbohydrates and Cell Development Book PDF

Author : Minoru Fukuda
Publisher : CRC Press
Page : 342 pages
File Size : 51,6 Mb
Release : 1991-12-13
Category : Science
ISBN : 0849364353

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Cell Surface Carbohydrates and Cell Development by Minoru Fukuda Pdf

Cell Surface Carbohydrates and Cell Development summarizes knowledge on the structure and function of cell surface carbohydrates in development and differentiation. The chapters include reviews on the expression of cell type-specific carbohydrates and their roles in cell-cell interaction. In particular, the role of cell surface carbohydrates in immune cell response, malignant transformation, fertilization, and neural cell development are addressed. This includes the exciting discovery about the role of adhesive molecules in leukocyte-endothellium interaction. Cell Surface Carbohydrates and Cell Development also summarizes the latest knowledge on structure and biosynthesis of carbohydrates, the role of specific carbohydrate modification, and animal lectins. The book will be useful to researchers and students interested in the biology of glycoproteins and biotechnology.

Glycosphingolipids in the Central Nervous System

Zhongwu Guo
Glycosphingolipids in the Central Nervous System Book PDF

Author : Zhongwu Guo
Publisher : Elsevier
Page : 455 pages
File Size : 54,7 Mb
Release : 2024-03-15
Category : Science
ISBN : 9780443161575

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Glycosphingolipids in the Central Nervous System by Zhongwu Guo Pdf

Glycosphingolipids in the Central Nervous System: Diversity in Structure, Metabolism, Distribution, and Function comprehensively covers progress made in the discovery, profiling and understanding of the metabolism, function and functional mechanism of GSLs in the CNS –as well as their synthesis, relationships with and therapeutic applications to neurodegenerative disorders, and related CNS diseases. Due to the important roles of GSLs in the CNS and various CNS-related diseases, the interest in these biomolecules is growing. GSLs are the principal glycolipids on the cell surface and an essential constituent of the cell membrane. They are widespread, but especially enriched in the central nervous system (CNS) in vertebrates. The diversity of GSL structures forges the molecular foundation for their broad spectrum of activity. Presents a systematic review of literature and potential future developments in Glycosphingolipid research Highlights interdisciplinary interplay between various aspects of the neuronal system and its structural and functional properties Provides an overview, general trends, cases studies, summaries and future implications