Governing Molecules

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Governing Molecules

Author : Herbert Gottweis
Publisher : MIT Press
Page : 418 pages
File Size : 42,7 Mb
Release : 1998-12-10
Category : Technology & Engineering
ISBN : 0262262789

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Governing Molecules by Herbert Gottweis Pdf

Scientists, investors, policymakers, the media, and the general public have all displayed a continuing interest in the commercial promise and potential dangers of genetic engineering. In this book, Herbert Gottweis explains how genetic engineering became so controversial—a technology that some seek to promote by any means and others want to block entirely. Beginning with a clear exposition of poststructuralist theory and its implications for research methodology, Gottweis offers a novel approach to political analysis, emphasizing the essential role of narratives in the development of policy under contemporary conditions. Drawing on more than eighty in-depth interviews and extensive archival work, Gottweis traces today's controversy back to the sociopolitical and scientific origins of molecular biology, paying particular attention to its relationship to eugenics. He argues that over the decades a number of mutually reinforcing political and scientific strategies have attempted to turn genes into objects of technological intervention—to make them "governable." Looking at critical events such as the 1975 Asilomar conference in the United States, the escalating conflict in Germany, and regulatory disputes in Britain and France during the 1980s, Gottweis argues that it was the struggle over boundaries and representations of genetic engineering, politics, and society that defined the political dynamics of the drafting of risk regulations in these countries. In a key chapter on biotechnology research, industry, and supporting technology policies, Gottweis demonstrates that the interpretation of genetic engineering as the core of a new "high technology" industry was part of a policy myth and an expression of identity politics. He suggests that under postmodern conditions a major strategy for avoiding policy failure is to create conditions that ensure tolerance and respect for the multiplicity of socially available policy narratives and reality interpretations.

Governing Molecules

Author : Herbert Gottweis
Publisher : Mit Press
Page : 397 pages
File Size : 40,6 Mb
Release : 1998
Category : Political Science
ISBN : 0262071894

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Governing Molecules by Herbert Gottweis Pdf

Herbert Gottweis explains how genetic engineering became so controversial. Beginning with an exposition of poststructuralist theory and its implications for research methodology, he approaches political analysis, emphasizing the essential role of narratives in the development of policy.

Genetic and Epigenetic Control on Immune Responses Regulating Molecules in Cancer Development, Progression, and Treatment

Author : Katherine Chiappinelli,Alejandro Villagra,Lidia Karabon
Publisher : Frontiers Media SA
Page : 308 pages
File Size : 47,8 Mb
Release : 2021-11-30
Category : Medical
ISBN : 9782889717309

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Genetic and Epigenetic Control on Immune Responses Regulating Molecules in Cancer Development, Progression, and Treatment by Katherine Chiappinelli,Alejandro Villagra,Lidia Karabon Pdf

Novel Plant Molecules Regulating the Interaction with Pathogenic and Beneficial Fungi

Author : Silvia Proietti,Ivan Baccelli,Richard Hickman,Antonio Leon-Reyes,Laura Bertini
Publisher : Frontiers Media SA
Page : 171 pages
File Size : 46,6 Mb
Release : 2021-03-26
Category : Science
ISBN : 9782889665686

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Novel Plant Molecules Regulating the Interaction with Pathogenic and Beneficial Fungi by Silvia Proietti,Ivan Baccelli,Richard Hickman,Antonio Leon-Reyes,Laura Bertini Pdf

Biology, Computing, and the History of Molecular Sequencing

Author : M. García-Sancho
Publisher : Springer
Page : 242 pages
File Size : 55,8 Mb
Release : 2012-05-11
Category : Science
ISBN : 9780230370937

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Biology, Computing, and the History of Molecular Sequencing by M. García-Sancho Pdf

Sequencing is often associated with the Human Genome Project and celebrated achievements concerning the DNA molecule. However, the history of this practice comprises not only academic biology, but also the world of computer-assisted information management. The book uncovers this history, qualifying the hype and expectations around genomics.

Exploring Life Phenomena with Statistical Mechanics of Molecular Liquids

Author : Fumio Hirata
Publisher : CRC Press
Page : 299 pages
File Size : 41,5 Mb
Release : 2020-02-12
Category : History
ISBN : 9781351201421

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Exploring Life Phenomena with Statistical Mechanics of Molecular Liquids by Fumio Hirata Pdf

In a living body, a variety of molecules are working in a concerted manner to maintain its life, and to carry forward the genetic information from generation to generation. A key word to understand such processes is "water," which plays an essential role in life phenomena. This book sheds light on life phenomena, which are woven by biomolecules as warp and water as weft, by means of statistical mechanics of molecular liquids, the RISM and 3D-RISM theories, both in equilibrium and non-equilibrium. A considerable number of pages are devoted to basics of mathematics and physics, so that students who have not majored in physics may be able to study the book by themselves. The book will also be helpful to those scientists seeking better tools for the computer-aided-drug-discovery. Explains basics of the statistical mechanics of molecular liquids, or RISM and 3D-RISM theories, and its application to water. Provides outline of the generalized Langevin theory and the linear response theory, and its application to dynamics of water. Applies the theories to functions of biomolecular systems. Applies the theories to the computer aided drug design. Provides a perspective for future development of the method.

Of Minds and Molecules

Author : Nalini Bhushan,Stuart M. Rosenfeld
Publisher : Oxford University Press, USA
Page : 316 pages
File Size : 48,7 Mb
Release : 2000
Category : Chemistry
ISBN : 9780195128345

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Of Minds and Molecules by Nalini Bhushan,Stuart M. Rosenfeld Pdf

Of Minds and Molecules is the first anthology devoted exclusively to work in the philosophy of chemistry. The essays, written by both chemists and philosophers, adopt distinctive philosophical perspectives on chemistry and collectively offer both a conceptualization of and a justification for this emerging field.

Molecular Science of Fluctuations Toward Biological Functions

Author : Mazahide Terazima,Mikio Kataoka,Ryuichi Ueoka,Yuko Okamoto
Publisher : Springer
Page : 270 pages
File Size : 54,6 Mb
Release : 2016-02-09
Category : Science
ISBN : 9784431558408

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Molecular Science of Fluctuations Toward Biological Functions by Mazahide Terazima,Mikio Kataoka,Ryuichi Ueoka,Yuko Okamoto Pdf

In this monograph, the importance of fluctuations for biological reactions is discussed from various points of view. Understanding the biological reactions at the molecular level is one of the major targets in many scientific fields, including not only basic biology but also physics, physical chemistry, and medical science. One of the key factors in the process is “fluctuation”. Thermal energy causes biological molecules to be in constant fluctuation even while they are carrying out their biological functions. How do biological systems overcome the thermal fluctuations to realize the physiologically relevant reactions? Scientists in a number of fields—physics, chemistry, pharmacology, medicine, and others—have contributed chapters that elucidate the nature of the fluctuations and the relationship between fluctuations and biological functions. The fluctuations discussed in this volume are detected by the transient grating method, nuclear magnetic resonance, X-ray diffraction and scattering, and computer simulation, among other methods. The book presents various results of the studies of fluctuations in biological processes that were obtained with these methods by the leading scientists in their fields.

Physico-Chemical Properties of Nanomaterials

Author : Richard C. Pleus,Vladimir Murashov
Publisher : CRC Press
Page : 212 pages
File Size : 44,9 Mb
Release : 2018-07-17
Category : Medical
ISBN : 9781351168588

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Physico-Chemical Properties of Nanomaterials by Richard C. Pleus,Vladimir Murashov Pdf

Throughout human history, we have long encountered the combination of promise, risk, and uncertainty that accompanies emerging technologies. Nanotechnology is a recent example of an emerging technology that promises to drastically improve existing products as well as allow for creative development of new goods and services. This new technology also has its potential downsides. Industry, academia, and regulatory agencies are all working overtime to assess risks accurately while keeping up with the pace of development. Subtle changes in the physicochemical properties of engineered nanomaterials (ENMs) can influence their toxicity and behavior in the environment and so can be used to help control potential ENM risks. This book attempts to encompass the state of the science regarding physicochemical characterization of ENMs. It illuminates the effort to understand these properties and how they may be used to ensure safe ENM deployment in existing or future materials and products.

Molecular Biology of The Cell

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 51,6 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

The Neutral Theory of Molecular Evolution

Author : Motoo Kimura
Publisher : Cambridge University Press
Page : 388 pages
File Size : 54,8 Mb
Release : 1983
Category : Science
ISBN : 0521317932

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The Neutral Theory of Molecular Evolution by Motoo Kimura Pdf

This book is the first comprehensive treatment of this subject.

Genome Finland

Author : Ilpo Helén,Karoliina Snell,Heta Tarkkala,Aaro Tupasela
Publisher : Helsinki University Press
Page : 310 pages
File Size : 40,7 Mb
Release : 2024-06-27
Category : Medical
ISBN : 9789523691070

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Genome Finland by Ilpo Helén,Karoliina Snell,Heta Tarkkala,Aaro Tupasela Pdf

Genome Finland tells a story of genomic medicine in Finland from the study of rare Finnish diseases in the 1960s and 1970s to the implementation of personalized medicine in the 2020s. The main focus is on the 21st century – the period after the Human Genome Project – and on the establishment of new infrastructures to support genomic medicine, such as biobanks. The book opens up the reasoning and discussions as well as the settings and events through which Finnish medical genetics reached the top level of international biomedicine in the late 1990s, biobanks and biobank research evolved during the 2000s and 2010s, and large transnational public-private partnership projects utilising massive amounts of genome and patient data started to dominate also Finnish research into the 2020s. In particular, Genome Finland examines and exposes the connections between biomedical science, ‘knowledge-based’ economy and business, and innovation policy in Finland during the past decades.

Who Wrote the Book of Life?

Author : Lily E. Kay
Publisher : Stanford University Press
Page : 476 pages
File Size : 53,6 Mb
Release : 2000
Category : Science
ISBN : 0804734178

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Who Wrote the Book of Life? by Lily E. Kay Pdf

This is a detailed history of one of the most important and dramatic episodes in modern science, recounted from the novel vantage point of the dawn of the information age and its impact on representations of nature, heredity, and society. Drawing on archives, published sources, and interviews, the author situates work on the genetic code (1953-70) within the history of life science, the rise of communication technosciences (cybernetics, information theory, and computers), the intersection of molecular biology with cryptanalysis and linguistics, and the social history of postwar Europe and the United States. Kay draws out the historical specificity in the process by which the central biological problem of DNA-based protein synthesis came to be metaphorically represented as an information code and a writing technology—and consequently as a “book of life.” This molecular writing and reading is part of the cultural production of the Nuclear Age, its power amplified by the centuries-old theistic resonance of the “book of life” metaphor. Yet, as the author points out, these are just metaphors: analogies, not ontologies. Necessary and productive as they have been, they have their epistemological limitations. Deploying analyses of language, cryptology, and information theory, the author persuasively argues that, technically speaking, the genetic code is not a code, DNA is not a language, and the genome is not an information system (objections voiced by experts as early as the 1950s). Thus her historical reconstruction and analyses also serve as a critique of the new genomic biopower. Genomic textuality has become a fact of life, a metaphor literalized, she claims, as human genome projects promise new levels of control over life through the meta-level of information: control of the word (the DNA sequences) and its editing and rewriting. But the author shows how the humbling limits of these scriptural metaphors also pose a challenge to the textual and material mastery of the genomic “book of life.”

Innovation, Regional Development and the Life Sciences

Author : Kean Birch
Publisher : Routledge
Page : 183 pages
File Size : 55,9 Mb
Release : 2016-10-14
Category : Business & Economics
ISBN : 9781317613817

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Innovation, Regional Development and the Life Sciences by Kean Birch Pdf

The life sciences is an industrial sector that covers the development of biological products and the use of biological processes in the production of goods, services and energy. This sector is frequently presented as a major opportunity for policy-makers to upgrade and renew regional economies, leading to social and economic development through support for high-tech innovation. Innovation, Regional Development and the Life Sciences analyses where innovation happens in the life sciences, why it happens in those places, and what this means for regional development policies and strategies. Focusing on the UK and Europe, its arguments are relevant to a variety of countries and regions pursuing high-tech innovation and development policies. The book’s theoretical approach incorporates diverse geographies (e.g. global, national and regional) and political-economic forces (e.g. discourses, governance and finance) in order to understand where innovation happens in the life sciences, where and how value circulates in the life sciences, and who captures the value produced in life sciences innovation. This book will be of interest to researchers, students and policy-makers dealing with regional/local economic development.

Vulnerability in Technological Cultures

Author : Anique Hommels,Jessica Mesman,Wiebe E. Bijker
Publisher : MIT Press
Page : 399 pages
File Size : 55,7 Mb
Release : 2014-03-21
Category : Political Science
ISBN : 9780262027106

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Vulnerability in Technological Cultures by Anique Hommels,Jessica Mesman,Wiebe E. Bijker Pdf

"Novel technologies and scientific advancements offer not only opportunities but risks. Technological systems are vulnerable to human error and technical malfunctioning that have far-reaching consequences: one flipped switch can cause a cascading power failure across a networked electric grid. Yet, once addressed, vulnerability accompanied by coping mechanisms may yield a more flexible and resilient society. This book investigates vulnerability, in both its negative and positive aspects, in technological cultures. The contributors argue that viewing risk in terms of vulnerability offers a novel approach to understanding the risks and benefits of science and technology. Such an approach broadens conventional risk analysis by connecting to issues of justice, solidarity, and livelihood, and enabling comparisons between the global north and south. The book explores case studies that range from agricultural practices in India to neonatal intensive care medicine in Western hospitals; these cases, spanning the issues addressed in the book, illustrate what vulnerability is and does. The book offers conceptual frameworks for empirical description and analysis of vulnerability that elucidate its ambiguity, context dependence, and constructed nature. Finally, the book addresses the implications of these analyses for the governance of vulnerability, proposing a more reflexive way of dealing with vulnerability in technological cultures"--