Green Chemistry Synthesis Of Bioactive Heterocycles
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Green Chemistry: Synthesis of Bioactive Heterocycles by K. L. Ameta,Anshu Dandia Pdf
The book presents a succinct summary of methods for the synthesis and biological activities of various different-sized bioactive heterocycles using different green chemistry synthetic methodologies, like microwave, ultrasonic, water mediated, ionic liquids, etc. The book also provides an insight of how green chemistry techniques are specific to the bioactive heterocyclic compounds.
Non-Conventional Synthesis by György Keglevich,Bubun Banerjee Pdf
Non-conventional synthetic methods may provide new and green methods for the preparation of bioactive heterocycles. These methods, such as microwave and ultrasound assisted synthesis, biocatalysis, photochemistry and electrosynthesis use less energy and may produce less waste to get the desired products when compared to traditional methods. This book explores the use of these methods when synthesizing various biologically relevant heterocyclic scaffolds. THE SERIES: GREEN BIOACTIVE HETEROCYCLES Heterocycles are a widely utilized group of molecules as they often contain bioactivity that is useful in drug development, agriculture, and other applications. However, their synthesis remains challenging with diffi cult to control functional groups. With a greater focus on sustainable synthesis practices, there is a need to develop greener synthetic methods for the synthesis of structurally diverse bioactive heterocyclic scaffolds. This series aims to do so, by collecting developments into common themes.
Author : Asit K. Chakraborti,Bubun Banerjee Publisher : Walter de Gruyter GmbH & Co KG Page : 587 pages File Size : 52,8 Mb Release : 2024-02-19 Category : Science ISBN : 9783110986099
Green Synthetic Approaches for Biologically Relevant Heterocycles by Goutam Brahmachari Pdf
Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume One: Advanced Synthetic Techniques reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume One explores advanced synthetic techniques, with each chapter presenting in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles that are classified on the basis of ring-size and/or the presence of heteroatoms. Techniques covered range from high pressure cycloaddition reactions and microwave irradiation to sustainable one-pot domino reactions. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry. Provides fully updated coverage of the field of greener heterocycle synthesis Includes new chapters on varied multicomponent reactions, alongside both traditional and novel approaches Presents information in an accessible style with an emphasis on sustainability
Solvent-Free Synthesis by Sreekantha B. Jonnalagadda,Bubun Banerjee Pdf
The solvent-free approach provides green and alternative synthetic methods for obtaining diverse bioactive heterocycles. The solvent is frequently the primary component of synthetic protocol and contributes to significant waste. Additionally, its removal processes are energy intensive and substantial. This book explores different solvent-free procedures for efficiently synthesising heterocyclic analogues of immense biological importance and other applications.
Green Synthetic Approaches for Biologically Relevant Heterocycles by Goutam Brahmachari Pdf
Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume Two: Green Catalytic Systems and Solvents reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume Two explores green catalytic systems and solvents and the techniques surrounding this approach, including metal and magnetic catalysis to organocatalysis and solid acid catalysis, cycloaddition reactions, and varied approaches using ionic liquids. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry. Provides fully updated coverage of the field with an emphasis on sustainability Highlights a range of different eco-friendly solvents and environmentally-friendly catalysts Collates the experience of a global team of expert contributors
Heterogeneous Catalysis by K.L. Ameta, Ph.D.,Andrea Penoni Pdf
For more than a century, bioactive heterocycles have formed one of the largest areas of research in organic chemistry. They are important from a biological and industrial point of view as well as to the understanding of life processes and efforts to improve the quality of life. Heterogeneous Catalysis: A Versatile Tool for the Synthesis of Bioactive Heterocycles highlights the recent methodologies used in the synthesis of such bioactive systems and focuses on the role of heterogeneous catalysis in the design and synthesis of various biologically active heterocyclic compounds of pharmacological interest. Topics include: Synthetic protocols for the construction of heterocyclic systems employing silica-bound catalysts Recent advances in heterogeneous copper-catalyzed reactions for the synthesis of bioactive heterocycles Features of silica-based heterogeneous catalysts, such as abundance, ease of use, and stability Ultrasound as an effective tool for accelerating reactions Organic transformations catalyzed by nano-ZnO as a valuable heterogeneous catalyst Heterogeneous catalysts employed in the synthesis of coumarins Heterocyclizations in the presence of silver salts Home-made organometallic silica sources, known as silatranes Reflecting the focused studies currently conducted in these areas, the book also examines anticancer, antifungal, antibacterial, anti-HIV, anti-inflammatory, antioxidant, and many more biological activities of heterocyclic compounds. It is essential reading for postgraduate and research scholars in the fields of biochemistry, chemical biology, medicinal chemistry and pharmaceutical chemistry.
Non-Metal Catalyzed Synthesis by Yunfei Du,Bubun Banerjee Pdf
Non-metal catalysis may provide new and green methods for obtaining bioactive heterocycles. Many catalysts contain metals, which can be toxic, energy intensive to remove, and require mining of the source materials. By utilizing metal-free catalysts we avoid these issues. This book explores the use of non-metal catalysts when synthesizing various heterocyclic structures with bioactivity.
Modern Green Chemistry and Heterocyclic Compounds by Ravindra S. Shinde,A. K. Haghi Pdf
This book covers the general properties of heterocyclic compounds and methods for their preparation to use in applications of green chemistry. Heterocyclic compounds are an important class of molecules in organic chemistry due to their presence in natural products and their use in pharmaceuticals and new materials. They also play a vital role in the metabolism of living cells. Heterocyclic compounds have a wide range of applications in agrochemicals, pharmaceuticals, veterinary products, etc. This research-oriented volume is ideal for readers who want to fully realize the almost limitless potential of heterocyclic compounds and to discover new and effective pharmaceuticals among heterocyclic compounds, the largest and most varied family of organic compounds. The book features several case studies and step-by-step descriptions of synthetic methods and practical techniques. It also serves as a guide for chemists, offering them new insights and new paths to explore for effective drug discovery.
Multicomponent Reactions by K.L. Ameta, Ph.D.,Anshu Dandia Pdf
This timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial applications are heterocyclic in nature. With the recent introduction of high-throughput biological evaluation, the importance of MCRs for drug discovery has been recognized and considerable efforts have been focused especially on the design and development of multi-component procedures for the generation of various bioactive heterocycles due to their significant therapeutic potential.
The field of nanocatalysis is undergoing rapid development. Nanocatalysis can help in designing catalysts with excellent activity, greater selectivity, and high stability. Their properties can easily be tuned by tailoring the size, shape, and morphology of the particular nanomaterial. Exhibiting both homogeneous and heterogeneous catalytic properties, nanocatalysts allow for rapid and selective chemical transformations, with the benefits of excellent product yield and ease of catalyst separation and recovery. Nanocatalysis: Synthesis of Bioactive Heterocycles reviews the catalytic performance and the synthesis and characterization of nanocatalysts, examining the current state of the art and pointing the way towards new avenues of research specially synthesis of bioactive heterocycles. Top researchers summarize synthetic methodologies for the synthesis of bioactive heterocycles using a nanocatalytic framework. The catalytic performance and the synthesis and characterization of nanocatalysts are reviewed. State of the art methods and new and emerging applications of nanocatalysts in the synthesis of biologically active heterocycles are detailed. Additional features include: Focuses on designing and synthesizing nanocatalysts specifically for the synthesis of different bioactive heterocycles. Demonstrates how nanocatalysis can produce catalysts with excellent activity, greater selectivity, and high stability. Explores tuning catalysts properties by tailoring the size, shape, and morphology of a nanomaterial. Offers the reader insights into the field of nanoscience via nanocatalysis. Nanocatalysis: Synthesis of Bioactive Heterocycles is a must read for researchers in organic chemistry, medicinal chemistry and biochemistry.
Author : Teresa M. V. D. Pinho e Melo,Marta Pineiro Publisher : John Wiley & Sons Page : 564 pages File Size : 41,6 Mb Release : 2022-06-20 Category : Science ISBN : 9783527348862
Heterocycles by Teresa M. V. D. Pinho e Melo,Marta Pineiro Pdf
Heterocycles A must-read handbook on heterocycle chemistry with a focus on sustainability Heterocycles feature prominently in our daily life—they are essential for pharmaceuticals, agrochemicals, and fine chemicals. More, numerous natural, bioactive products contain heterocyclic compounds. As a result, heterocyclic chemistry continues to be one of the most important areas of study in organic chemistry. Heterocycles provides an important reference on a wide range of topics relating to heterocyclic chemistry, with a heavy emphasis on sustainable methods and greener syntheses. The book describes state-of-the-art synthetic methods, such as photochemical reactions, dearomatization reactions, organocatalysis, transition metal catalysis, and biocatalysis. It also covers: Sustainable methods, like flow chemistry, mechanochemistry, and multicomponent synthesis Strategies for the synthesis of heterocyclic macrocycles and medium-sized rings Characterization of heterocyclic compounds Heterocycles is a useful reference for organic chemists, natural products chemists, catalytic chemists, and medicinal chemists in academia and industry.
Synthesis of Bioactive Scaffolds by Rakesh Kumar Sharma,Bubun Banerjee Pdf
Carbon-carbon and carbon-heteroatom bond-forming reactions are the backbone of synthetic organic chemistry. Scientists are constantly developing and improving these techniques in order to maximize the diversity of synthetically available molecules. These techniques must be developed in a sustainable manner in order to limit their environmental impact. This book highlights green bond forming reactions for bioactive scaffolds.