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Author : P.P. Rumyantsev
Publisher : Routledge
Page : 400 pages
File Size : 41,6 Mb
Release : 2017-09-19
Category : Medical
ISBN : 9781134338610
First Published in 1991. This Volume three of a set of a monograph series publishing versions of some of the research reviewed in its companion series, Section A (Cardiology Reviews) of Soviet Medical Reviews.
Author : Naranjan S. Dhalla,Larry Hryshko,Elissavet Kardami,Pawan K. Singal
Publisher : Springer Science & Business Media
Page : 778 pages
File Size : 41,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461503477
Cellular signaling in cardiac muscle refers to the myriad of stimuli and responses that direct and control the physiological operation of this organ. Our understand ing of these complex signaling cascades has increased dramatically over the past few decades with the advent of molecular tools for their dissection. Moreover, this infor mation is beginning to provide tangible targets towards manipulating cardiac func tion in the setting of cardiovascular disease. The mechanisms and factors that regulate cardiac cell growth are of particular interest as both adaptive and maladaptive responses can occur during cardiac hypertrophy. Cardiac hypertrophy describes the increase in individual cardiac myocyte size that is accomplished through the series and/or parallel addition of sarcomeres. The ability of cardiac muscle to increase in size through hyperplasia becomes highly restricted or negligible shortly after birth. Consequently, the increase in heart size associated with development and growth of an individual occurs through hypertrophy. In response to a chronic increase in workload, cardiac muscle cells can dramatically increase in size to face their increasing contractile demands. While this plasticity is clearly a ben eficial response under many conditions, it can be highly deleterious and inappropri ate under others. For example, cardiac hypertrophy associated with endurance exercise clearly enhances athletic performance. In contrast, the hypertrophy associated with chronic hypertension, stenotic or regurgitant heart valves, or following a myocardial infarction often continues far beyond the period where this adaptive response is ben eficial.
Author : Radovan Zak
Publisher : Raven Press (ID)
Page : 504 pages
File Size : 55,5 Mb
Release : 1984
Category : Medical
ISBN : UOM:39015006021615
Author : P.P. Rumyantsev
Publisher : Routledge
Page : 389 pages
File Size : 47,9 Mb
Release : 2017-09-19
Category : Medical
ISBN : 9781134338542
First Published in 1991. This Volume three of a set of a monograph series publishing versions of some of the research reviewed in its companion series, Section A (Cardiology Reviews) of Soviet Medical Reviews.
Author : William C. Claycomb,Paolo Di Nardo
Publisher : Unknown
Page : 560 pages
File Size : 52,7 Mb
Release : 1995
Category : Blood-vessels
ISBN : UVA:X002594909
Mammalian cardiac muscle, unlike that in amphibians, reptiles and the mammalian atrium, cannot regenerate after injury, and the mechanism for the irreversible blockage of mitosis in these monocytes during early development is still not understood. This book attempts to study the mechanisms that control the cardiac muscle cell cycle so that treatments to initiate repair of the myocardium can be designed. An ideal model would allow study of cardiac muscle cells in the intact heart in the biochemical state they were in during foetal growth, when they were actively dividing. This volume gathers the most current information dealing with the regenerative potential of cardiac muscle in the vertebrate heart.
Author : National Research Council,Board on Agriculture,Committee on Technological Options to Improve the Nutritional Attributes of Animal Products
Publisher : National Academies Press
Page : 384 pages
File Size : 53,6 Mb
Release : 1988-02-01
Category : Medical
ISBN : 9780309037983
This lively book examines recent trends in animal product consumption and diet; reviews industry efforts, policies, and programs aimed at improving the nutritional attributes of animal products; and offers suggestions for further research. In addition, the volume reviews dietary and health recommendations from major health organizations and notes specific target levels for nutrients.
Author : Robert Fitridge,M. M. Thompson
Publisher : University of Adelaide Press
Page : 589 pages
File Size : 41,8 Mb
Release : 2011
Category : Medical
ISBN : 9781922064004
New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Author : J. Gordon Betts,Peter DeSaix,Jody E. Johnson,Oksana Korol,Dean H. Kruse,Brandon Poe,James A. Wise,Mark Womble,Kelly A. Young
Publisher : Unknown
Page : 0 pages
File Size : 47,9 Mb
Release : 2013-04-25
Category : Electronic
ISBN : 1947172808
Author : John J. Spitzer
Publisher : Springer Science & Business Media
Page : 600 pages
File Size : 48,9 Mb
Release : 2013-03-09
Category : Medical
ISBN : 9781468444728
The chapters of this book represent contributions by plenary lecturers and invited symposium speakers of the Fourth Annual Meet ing of the American Section of the International Society for Heart Research, held on May 26-29, 1982 in New Orleans, Louisiana. The aim of the Organizing Committee was to present an up-to-date picture of our knowledge of myocardial injury which would be equally useful to basic scientists and clinicians. The papers of this volume are divided into two groups: a) those dealing primarily with techniques to study myocardial injury, and b) those that discuss the different types of myocardial lnJury. The grouping of the papers within each of these headings roughly corresponds to the symposia presented at the meeting. I wish to acknowledge the financial support of the National Institutes of Health. Without grant HL 29149, the program could not have been financed. Contributions from the following companies were also gratefully received: Ayerst Laboratories, Ciba-Geigy, Merck Sharp and Dome, Pfizer Laboratories Division, A.H. Robbin Co., Smith-Kline Corporation, U.S.V. Pharmaceutical Co., and The Upjohn Co. My thanks are due to the members of The Organizing Committee (Drs. Gregory J. Bagby, Gerald S. Berenson, Alastair H. Burns, Harvey I. Miller, Robert Roskoski, Jr., and Judy A. Spitzer) for their help and support, and to the Secretary of the Meeting, Ms. L. Beatrice Abene for her excellent assistance. John J. Spitzer, M.D.
Author : Frank C. Mooren
Publisher : Springer
Page : 0 pages
File Size : 44,7 Mb
Release : 2012-04-19
Category : Medical
ISBN : 3540360654
The Encyclopedia of Exercise Medicine is intelligently structured, easy accessible and user-friendly: A-Z format, clear, concise language and uniform essay structure as well as extensive cross references between keywords and related articles enables efficient searches in a user-friendly manner both for experts and newcomers. It is intended to be a comprehensive up-to-date data base on the adaptation of the human body to exercise and on the therapeutic use of exercise with up to 2,000 keywords. It covers all aspects within the full range of modern exercise medicine of each particular scientific discipline (cancer, parasitology, aging, etc.). This includes information on methodological approaches to measuring the principle components of motor fitness, and practical aspects of their enhancement by trainings regimes as well as by nutrition and the application of drugs. Such a wide range of entries, all written by leading experts in their respective fields, will therefore address both the basic/clinical scientist as well as the practitioner. Moreover, the Encyclopedia of Exercise Medicine is aimed at people in related fields, health care professionals, physiotherapists, trainers, students, informed athletes and interested laypersons. It is available both in print and as a fully searchable and hyperlinked electronic online edition.
Author : Masaki Ieda,Wolfram-Hubertus Zimmermann
Publisher : Springer
Page : 274 pages
File Size : 45,7 Mb
Release : 2017-10-27
Category : Medical
ISBN : 9783319561066
This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair. Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged. The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.
Author : Sue E. Huether,Kathryn L. McCance
Publisher : Elsevier Health Sciences
Page : 1187 pages
File Size : 46,9 Mb
Release : 2013-12-27
Category : Medical
ISBN : 9780323293433
Learn the essential concepts of pathophysiology and stay up to date on treatments, manifestations, and mechanisms of disease with Understanding Pathophysiology, 5th Edition. Filled with vibrant illustrations and complemented by online resources that bring pathophysiology concepts to life, this easy-to-read text delivers the latest, most accurate information on the disease process across the lifespan, giving you the fundamental knowledge you need to move forward in your nursing education. Consistent presentation helps you better distinguish pathophysiology, clinical manifestations, and evaluation and treatment for each disease. More than 1,000 high-quality illustrations vividly depict clinical manifestations and cellular mechanisms underlying diseases. Lifespan coverage details age-specific conditions affecting pediatric, adult, and aging patients in great depth. Algorithms throughout the text clarify disease progression. Risk Factor boxes alert you to important safety considerations associated with specific diseases. Health Alert boxes highlight new developments in biologic research, diagnostic studies, preventive care, treatments, and more. Quick Check boxes test your retention of important chapter concepts. Did You Understand? sections provide fast, efficient review of chapter content. Chapter outlines help you find specific information with ease. Chapter introductions explain why chapter content is important and how it fits into a broader health care context. Key terms are bolded throughout the text for fast, easy reference. Glossary of selected terms familiarizes you with the most difficult or important terminology. Companion Evolve website provides convenient online access to animations, review questions, key terms matching exercises, and more. NEW! Extensively updated content reflects the latest clinical findings and research across the full spectrum of pathophysiology. NEW! Hundreds of new and enhanced full-color illustrations clarify anatomy and physiologic concepts. NEW! 30 new animations on the companion Evolve website reinforce your understanding of complex processes.
Author : M. Asif Chaudry,James Kinross,Shahnawaz Rasheed
Publisher : Elsevier Health Sciences
Page : 906 pages
File Size : 54,7 Mb
Release : 2022-11-29
Category : Medical
ISBN : 9780702070525
Clinical Surgery provides a complete overview of all surgical specialties, and is suitable for advanced undergraduates through to surgical trainees preparing for the FRCS. This comprehensive textbook is designed around the Intercollegiate Surgical Curriculum Programme (ISCP) framework, and provides information needed for passing MCQs, OSCEs and Vivas in the one book. Information is divided into three clear sections: basic science and surgical strategy; common surgical conditions and trauma; and leadership, evidence-based practice and global surgery. This fourth edition has been fully updated and restructured by a new editorial team. Older concepts have been replaced by a new focus on systems biology, omics sciences and multidisciplinary sciences, and the book presents a modern, inclusive view of the surgeon as part of a multidisciplinary team delivering high quality care. Comprehensive and accessible – all you need in the one book Information presented logically and clearly in three clear sections Aligns with the ISCP – designed for surgical trainees Highly illustrated to support understanding Detailed practice information and summaries of complex themes to aid with preparation for exams Practical steps designed to facilitate procedural based learning and OSCEs Entirely revised to follow the Intercollegiate Surgical Curriculum (ISC) New focus on prevention of surgical disease Introduction of sections on surgical safety and quality improvement New sections on the elderly surgical patients, the dying patient and surgical technology
Author : Kathryn L. McCance,Sue E. Huether
Publisher : Elsevier Health Sciences
Page : 1908 pages
File Size : 47,9 Mb
Release : 2013-12-18
Category : Medical
ISBN : 9780323293754
With easy-to-read, in-depth descriptions of disease, disease etiology, and disease processes, Pathophysiology: The Biologic Basis for Disease in Adults and Children, 7th Edition helps you understand the most important and the most complex pathophysiology concepts. More than 1,200 full-color illustrations and photographs make it easier to identify normal anatomy and physiology, as well as alterations of function. This edition includes a NEW Epigenetics and Disease chapter along with additional What’s New boxes highlighting the latest advances in pathophysiology. Written by well-known educators Kathryn McCance and Sue Huether, and joined by a team of expert contributors, this resource is the most comprehensive and authoritative pathophysiology text available! Over 1,200 full-color illustrations and photographs depict the clinical manifestations of disease and disease processes — more than in any other pathophysiology text. A fully updated glossary includes 1,000 terms, and makes lookup easier by grouping together similar topics and terms. Outstanding authors Kathryn McCance and Sue Huether have extensive backgrounds as researchers and instructors, and utilize expert contributors, consultants, and reviewers in developing this edition. Chapter summary reviews provide concise synopses of the main points of each chapter. Consistent presentation of diseases includes pathophysiology, clinical manifestations, and evaluation and treatment. Lifespan content includes ten separate pediatric chapters and special sections with aging and pediatrics content. Algorithms and flowcharts of diseases and disorders make it easy to follow the sequential progression of disease processes. Nutrition and Disease boxes explain the link between concepts of health promotion and disease. Updated content on leukocytes in pain modulation, seizure disorders, brain injuries and disorders, acute encephalopathies, reproductive disorders, and much more keep you at the cutting edge of this constantly changing field. What’s New? boxes highlight the most current research and findings to ensure you have the most up-to-date information. New animations, review questions, Key Points, and an audio glossary have been added to the Evolve companion website to strengthen your understanding of key concepts. Media Resources Lists encourage you to develop a study plan to master the important content in each chapter.
Author : U. S. Department of Health and Human Services,National Insitutes of Health,National Heart Lung Institute, And
Publisher : CreateSpace
Page : 102 pages
File Size : 46,7 Mb
Release : 2013-06-21
Category : Medical
ISBN : 149050057X
The purpose of the “Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7)” is to provide an evidence-based approach to the prevention and management of hypertension. The key messages of this report are: in those older than age 50, systolic blood pressure (SBP) of greater than 140 mmHg is a more important cardiovascular disease (CVD) risk factor than diastolic BP (DBP); beginning at 115/75 mmHg, CVD risk doubles for each increment of 20/10 mmHg; those who are normotensive at 55 years of age will have a 90 percent lifetime risk of developing hypertension; prehypertensive individuals (SBP 120–139 mmHg or DBP 80–89 mmHg) require health promoting lifestyle modifications to prevent the progressive rise in blood pressure and CVD; for uncomplicated hypertension, thiazide diuretic should be used in drug treatment for most, either alone or combined with drugs from other classes; this report delineates specific high-risk conditions, which are compelling indications for the use of other antihypertensive drug classes (angiotensin-converting enzyme inhibitors, angiotensin-receptor blockers, beta blockers, calcium channel blockers); two or more antihypertensive medications will be required to achieve goal BP (less than 140/90 mmHg, or less than 130/80 mmHg for patients with diabetes and chronic kidney disease); for patients whose BP is greater than 20 mmHg above the SBP goal or 10 mmHg above the DBP goal, initiation of therapy using two agents, one of which usually will be a thiazide diuretic, should be considered; regardless of therapy or care, hypertension will only be controlled if patients are motivated to stay on their treatment plan. Positive experiences, trust in the clinician, and empathy improve patient motivation and satisfaction. This report serves as a guide, and the committee continues to recognize that the responsible physician's judgment remains paramount.