Handbook Of Bioanalytics

Author : Bogusław Buszewski,Irena Baranowska
Publisher : Springer Nature
Page : 1091 pages
File Size : 47,7 Mb
Release : 2022-06-30
Category : Science
ISBN : 9783030956608

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Handbook of Bioanalytics by Bogusław Buszewski,Irena Baranowska Pdf

This book presents an authoritative review of analytical methods used for diagnostics, medical therapy and for forensic purposes. Divided into 4 parts, the book discusses new challenges in bioanalytics, covers bioanalysis as a source of clinical, pharmaceutical and forensic information, explores natural resources as a source of biologically active compounds, and offers new analytical strategies and equipment solutions. Written by interdisciplinary expert academics, this work will appeal to a wide readership of students, researchers and professionals interested in the fields of medicine, chemistry, pharmaceutical, life and health sciences, engineering and environmental protection. Clinicians and employees of forensic laboratories will also find this work instructive and informative.

Author : Gary Evans
Publisher : CRC Press
Page : 412 pages
File Size : 40,8 Mb
Release : 2004-03-29
Category : Medical
ISBN : 0203642538

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A Handbook of Bioanalysis and Drug Metabolism by Gary Evans Pdf

Recent years have seen a greater industrial emphasis in undergraduate and postgraduate courses in the pharmaceutical and chemical sciences. However, textbooks have been slow to adapt, leaving the field without a text/reference that is both instructional and practical in the industrial setting – until now. A Handbook of Bioanalysis and Drug Metabolismis a stimulating new text that examines the techniques, methodology, and theory of bioanalysis, pharmacokinetics, and metabolism from the perspective of scientists with extensive professional experience in drug discovery and development. These three areas of research help drug developers to optimize the active component within potential drugs thereby increasing their effectiveness, and to provide safety and efficacy information required by regulators when granting a drug license. Professionals with extensive experience in drug discovery and development as well as specialized knowledge of the individual topics contributed to each chapter to create a current and well-credentialed text. It covers topics such as high performance liquid chromatography, protein binding, pharmacokinetics and drug–drug interactions. The unique industrial perspective helps to reinforce theory and develop valuable analytical and interpreting skills. This text is an invaluable guide to students in courses such as pharmaceutical science, pharmacology, chemistry, physiology and toxicology, as well as professionals in the biotechnology industry.

Author : Wenkui Li,Jie Zhang,Francis L. S. Tse
Publisher : John Wiley & Sons
Page : 709 pages
File Size : 47,7 Mb
Release : 2013-09-03
Category : Science
ISBN : 9781118671351

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Handbook of LC-MS Bioanalysis by Wenkui Li,Jie Zhang,Francis L. S. Tse Pdf

Consolidates the information LC-MS bioanalytical scientists need to analyze small molecules and macromolecules The field of bioanalysis has advanced rapidly, propelled by new approaches for developing bioanalytical methods, new liquid chromatographic (LC) techniques, and new mass spectrometric (MS) instruments. Moreover, there are a host of guidelines and regulations designed to ensure the quality of bioanalytical results. Presenting the best practices, experimental protocols, and the latest understanding of regulations, this book offers a comprehensive review of LC-MS bioanalysis of small molecules and macromolecules. It not only addresses the needs of bioanalytical scientists working on routine projects, but also explores advanced and emerging technologies such as high-resolution mass spectrometry and dried blood spot microsampling. Handbook of LC-MS Bioanalysis features contributions from an international team of leading bioanalytical scientists. Their contributions reflect a review of the latest findings, practices, and regulations as well as their own firsthand analytical laboratory experience. The book thoroughly examines: Fundamentals of LC-MS bioanalysis in drug discovery, drug development, and therapeutic drug monitoring The current understanding of regulations governing LC-MS bioanalysis Best practices and detailed technical instructions for LC-MS bioanalysis method development, validation, and stability assessment of analyte(s) of interest Experimental guidelines and protocols for quantitative LC-MS bioanalysis of challenging molecules, including pro-drugs, acyl glucuronides, N-oxides, reactive compounds, and photosensitive and autooxidative compounds With its focus on current bioanalytical practice, Handbook of LC-MS Bioanalysis enables bioanalytical scientists to develop and validate robust LC-MS assay methods, all in compliance with current regulations and standards.

Author : Friedrich Lottspeich,Joachim W. Engels
Publisher : John Wiley & Sons
Page : 1151 pages
File Size : 49,9 Mb
Release : 2018-05-29
Category : Science
ISBN : 9783527339198

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Bioanalytics by Friedrich Lottspeich,Joachim W. Engels Pdf

Analytical methods are the essential enabling tools of the modern biosciences. This book presents a comprehensive introduction into these analytical methods, including their physical and chemical backgrounds, as well as a discussion of the strengths and weakness of each method. It covers all major techniques for the determination and experimental analysis of biological macromolecules, including proteins, carbohydrates, lipids and nucleic acids. The presentation includes frequent cross-references in order to highlight the many connections between different techniques. The book provides a bird's eye view of the entire subject and enables the reader to select the most appropriate method for any given bioanalytical challenge. This makes the book a handy resource for students and researchers in setting up and evaluating experimental research. The depth of the analysis and the comprehensive nature of the coverage mean that there is also a great deal of new material, even for experienced experimentalists. The following techniques are covered in detail: - Purification and determination of proteins - Measuring enzymatic activity - Microcalorimetry - Immunoassays, affinity chromatography and other immunological methods - Cross-linking, cleavage, and chemical modification of proteins - Light microscopy, electron microscopy and atomic force microscopy - Chromatographic and electrophoretic techniques - Protein sequence and composition analysis - Mass spectrometry methods - Measuring protein-protein interactions - Biosensors - NMR and EPR of biomolecules - Electron microscopy and X-ray structure analysis - Carbohydrate and lipid analysis - Analysis of posttranslational modifications - Isolation and determination of nucleic acids - DNA hybridization techniques - Polymerase chain reaction techniques - Protein sequence and composition analysis - DNA sequence and epigenetic modification analysis - Analysis of protein-nucleic acid interactions - Analysis of sequence data - Proteomics, metabolomics, peptidomics and toponomics - Chemical biology

Author : Wolfgang Fritzsche,Jürgen Popp
Publisher : Springer Science & Business Media
Page : 332 pages
File Size : 48,5 Mb
Release : 2012-02-03
Category : Science
ISBN : 9783642254987

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Optical Nano- and Microsystems for Bioanalytics by Wolfgang Fritzsche,Jürgen Popp Pdf

This book describes the state of the art in the field of bioanalytical nano- and microsystems with optical functionality. In 12 chapters distinguished scientists and leaders in their respective fields show how various optical technologies have been miniaturized and integrated over the last few decades in order to be combined with nano- and microsystems for applications in the life sciences. The main detection and characterization technologies are introduced, and examples of the superiority of these integrated approaches compared to traditional ones are provided. Examples from e.g. the fields of optical waveguides, integrated interferometers, surface plasmon resonance or Raman spectroscopy are introduced and discussed, and it is shown how these approaches have led to novel functionalities and thereby novel applications.

Author : Ankit Agarwal
Publisher : Springer Nature
Page : 204 pages
File Size : 51,9 Mb
Release : 2024-07-01
Category : Electronic
ISBN : 9783031604362

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Towards Water Circular Economy by Ankit Agarwal Pdf

Author : Jun Zhou,Hongbiao Cui,Zhu Li,Chunhao Gu,Buyun Du
Publisher : Frontiers Media SA
Page : 190 pages
File Size : 42,8 Mb
Release : 2023-02-09
Category : Science
ISBN : 9782832511121

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Soil and sediment pollution, processes and remediation, volume II by Jun Zhou,Hongbiao Cui,Zhu Li,Chunhao Gu,Buyun Du Pdf

Author : G¿nter Gauglitz,David S. Moore
Publisher : John Wiley & Sons
Page : 2011 pages
File Size : 51,7 Mb
Release : 2014-05-05
Category : Science
ISBN : 9783527654727

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Handbook of Spectroscopy by G¿nter Gauglitz,David S. Moore Pdf

This second, thoroughly revised, updated and enlarged edition provides a straightforward introduction to spectroscopy, showing what it can do and how it does it, together with a clear, integrated and objective account of the wealth of information that may be derived from spectra. It also features new chapters on spectroscopy in nano-dimensions, nano-optics, and polymer analysis. Clearly structured into sixteen sections, it covers everything from spectroscopy in nanodimensions to medicinal applications, spanning a wide range of the electromagnetic spectrum and the physical processes involved, from nuclear phenomena to molecular rotation processes. In addition, data tables provide a comparison of different methods in a standardized form, allowing readers to save valuable time in the decision process by avoiding wrong turns, and also help in selecting the instrumentation and performing the experiments. These four volumes are a must-have companion for daily use in every lab.

Author : Jürgen Popp,Valery V. Tuchin,Arthur Chiou,Stefan H. Heinemann
Publisher : John Wiley & Sons
Page : 321 pages
File Size : 52,8 Mb
Release : 2012-05-14
Category : Science
ISBN : 9783527410491

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Handbook of Biophotonics, Volume 3 by Jürgen Popp,Valery V. Tuchin,Arthur Chiou,Stefan H. Heinemann Pdf

This new handbook covers the world of biophotonics not only geographically -- with the editors coming from different continents -- but also in terms of content, since the authors come from the whole spectrum of biophotonic basic and applied research. Designed to set the standard for the scientific community, these three volumes break new ground by providing readers with the physics basics as well as the biological and medical background, together with detailed reports on recent technical advances. The Handbook also adopts an application-related approach, starting with the application and then citing the various tools to solve the scientific task, making it of particular value to medical doctors. Divided into several sections, the first part offers introductory chapters on the different fields of research, with subsequent parts focusing on the applications and techniques in various fields of industry and research. The result is a handy source for scientists seeking the basics in a condensed form, and equally a reference for quickly gathering the knowledge from neighboring disciplines. Absolutely invaluable for biophotonic scientists in their daily work.

Author : G¿nter Gauglitz,Tuan Vo-Dinh
Publisher : John Wiley & Sons
Page : 1168 pages
File Size : 54,5 Mb
Release : 2006-03-06
Category : Science
ISBN : 9783527605026

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Handbook of Spectroscopy by G¿nter Gauglitz,Tuan Vo-Dinh Pdf

This handbook provides a straightforward introduction to spectroscopy, showing what it can do and how it does it, together with a clear, integrated and objective account of the wealth of information that can be derived from spectra. The sequence of chapters covers a wide range of the electromagnetic spectrum, and the physical processes involved, from nuclear phenomena to molecular rotation processes. - A day-by-day laboratory guide: its design based on practical knowledge of spectroscopists at universities, industries and research institutes - A well-structured information source containing methods and applications sections framed by sections on general topics - Guides users to a decision about which spectroscopic method and which instrumentation will be the most appropriate to solve their own practical problem - Rapid access to essential information - Correct analysis of a huge number of measured spectra data and smart use of such information sources as databases and spectra libraries

Author : Irena Baranowska
Publisher : Springer
Page : 453 pages
File Size : 51,9 Mb
Release : 2015-08-13
Category : Science
ISBN : 9783319196145

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Handbook of Trace Analysis by Irena Baranowska Pdf

This handbook is unique in its comprehensive coverage of the subject and focus on practical applications in diverse fields. It includes methods for sample preparation, the role of certified reference materials, calibration methods and statistical evaluation of the results. Problems concerning inorganic and bioinorganic speciation analysis, as well as special aspects such as trace analysis of noble metals, radionuclides and volatile organic compounds are also discussed. A significant part of the content presents applications of methods and procedures in medicine (metabolomics and therapeutic drug monitoring); pharmacy (the analysis of contaminants in drugs); studies of environmental samples; food samples and forensic analytics – essential examples that will also facilitate problem solving in related areas.

Author : Abhilasha Shourie
Publisher : The Energy and Resources Institute (TERI)
Page : 424 pages
File Size : 45,5 Mb
Release : 2005-01-01
Category : Science
ISBN : 9788179935293

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Bioanalytical Techniques by Abhilasha Shourie Pdf

Bioanalytical Techniques form an integral part of applied biology and biomedical sciences. The various principles of bioanalytical techniques used in biomedical sciences, environmental studies, life sciences, pharmaceutical analysis, molecular biology, and biotechnological research are comprehensively discussed in this book. Analytical instrumentation is also explained in as concise a manner as possible. Microscopy, centrifugation, chromatography, electrophoresis, spectroscopy, and radioisotope and immunodiagnostic techniques are the main topics focussed in this book. Techniques in molecular biology and recombinant DNA technology have also been described in detail.

Author : Friedrich Lottspeich,Joachim W. Engels
Publisher : John Wiley & Sons
Page : 450 pages
File Size : 53,6 Mb
Release : 2018-03-08
Category : Science
ISBN : 9783527694440

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Bioanalytics by Friedrich Lottspeich,Joachim W. Engels Pdf

Analytical methods are the essential enabling tools of the modern biosciences. This book presents a comprehensive introduction into these analytical methods, including their physical and chemical backgrounds, as well as a discussion of the strengths and weakness of each method. It covers all major techniques for the determination and experimental analysis of biological macromolecules, including proteins, carbohydrates, lipids and nucleic acids. The presentation includes frequent cross-references in order to highlight the many connections between different techniques. The book provides a bird's eye view of the entire subject and enables the reader to select the most appropriate method for any given bioanalytical challenge. This makes the book a handy resource for students and researchers in setting up and evaluating experimental research. The depth of the analysis and the comprehensive nature of the coverage mean that there is also a great deal of new material, even for experienced experimentalists. The following techniques are covered in detail: - Purification and determination of proteins - Measuring enzymatic activity - Microcalorimetry - Immunoassays, affinity chromatography and other immunological methods - Cross-linking, cleavage, and chemical modification of proteins - Light microscopy, electron microscopy and atomic force microscopy - Chromatographic and electrophoretic techniques - Protein sequence and composition analysis - Mass spectrometry methods - Measuring protein-protein interactions - Biosensors - NMR and EPR of biomolecules - Electron microscopy and X-ray structure analysis - Carbohydrate and lipid analysis - Analysis of posttranslational modifications - Isolation and determination of nucleic acids - DNA hybridization techniques - Polymerase chain reaction techniques - Protein sequence and composition analysis - DNA sequence and epigenetic modification analysis - Analysis of protein-nucleic acid interactions - Analysis of sequence data - Proteomics, metabolomics, peptidomics and toponomics - Chemical biology

Author : Richard B. M. Schasfoort
Publisher : Royal Society of Chemistry
Page : 555 pages
File Size : 43,6 Mb
Release : 2017-05-30
Category : Science
ISBN : 9781782627302

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Handbook of Surface Plasmon Resonance by Richard B. M. Schasfoort Pdf

Surface plasmon resonance (SPR) plays a dominant role in real-time interaction sensing of biomolecular binding events, this book provides a total system description including optics, fluidics and sensor surfaces for a wide researcher audience.

Author : Jürgen Popp,Valery V. Tuchin,Arthur Chiou,Stefan H. Heinemann
Publisher : John Wiley & Sons
Page : 1187 pages
File Size : 54,5 Mb
Release : 2011-11-30
Category : Science
ISBN : 9783527410484

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Handbook of Biophotonics by Jürgen Popp,Valery V. Tuchin,Arthur Chiou,Stefan H. Heinemann Pdf

This new handbook covers the world of biophotonics not only geographically -- with the editors coming from different continents -- but also in terms of content, since the authors come from the whole spectrum of biophotonic basic and applied research. Designed to set the standard for the scientific community, these three volumes break new ground by providing readers with the physics basics as well as the biological and medical background, together with detailed reports on recent technical advances. The Handbook also adopts an application-related approach, starting with the application and then citing the various tools to solve the scientific task, making it of particular value to medical doctors. Divided into several sections, the first part offers introductory chapters on the different fields of research, with subsequent parts focusing on the applications and techniques in various fields of industry and research. The result is a handy source for scientists seeking the basics in a condensed form, and equally a reference for quickly gathering the knowledge from neighboring disciplines. Absolutely invaluable for biophotonic scientists in their daily work.