Handbook Of Human Tissue Sources A National Resource Of Human Tissue Samples
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Handbook of Human Tissue Sources. A National Resource of Human Tissue Samples by Anonim Pdf
One aspect of the recent and rapid advances in biological and medical research is that human tissue is being used in an increasing variety of new ways. Now that techniques exist to extract DNA from minuscule archival samples, Including frozen blood or tissue samples and even paraffin-embedded tissue blocks, genetic tests could potentially be performed on virtually any size stored tissue sample. These technological advances, which have been so instrumental in recent biomedical discoveries, have also raised several legal, ethical, and societal issues, including concerns about privacy and informed consent.
Case Studies of Existing Human Tissue Repositories by Elisa Eiseman,Gabrielle Bloom,Jennifer Brower,Noreen Clancy,Stuart S. Olmsted Pdf
Case studies of twelve existing human biospecimen repositories performed to evaluate their utility for genomics- and proteomics-based cancer research and to identify "best practices" in collection, processing, annotation, storage, privacy, ethical concerns, informed consent, business plans, operations, intellectual property rights, public relations, marketing, and education that would be useful in designing a national biospecimen network.
Author : Robert F. Weir,Robert S. Olick,Jeffrey C. Murray Publisher : Oxford University Press Page : 358 pages File Size : 53,6 Mb Release : 2004-05-20 Category : Medical ISBN : 9780195123685
The Stored Tissue Issue by Robert F. Weir,Robert S. Olick,Jeffrey C. Murray Pdf
This book provides a thorough, well-balanced analysis of common research practices with banked tissues, DNA, and genetic data. Describing many examples of beneficial tissue research, the authors focus on problematic research practices, controversial cases, and federal and institutional policies that limit the informed choices of patients and research participants. They offer a series of recommendations to help overcome these problems.
With Biotechnology and Society, Hallam Stevens offers an up-to-date primer to help us understand the interactions of biotechnology and society and the debates, controversies, fears, and hopes that have shaped how we think about bodies, organisms, and life in the twenty-first century. Stevens addresses such topics as genetically modified foods, cloning, and stem cells; genetic testing and the potential for discrimination; fears of (and, in some cases, hopes for) designer babies; personal genomics; biosecurity; and biotech art. Taken as a whole, the book presents a clear, authoritative picture of the relationship between biotechnology and society today, and how our conceptions (and misconceptions) of it could shape future developments. It is an essential volume for students and scholars working with biotechnology, while still being accessible to the general reader interested in the truth behind breathless media accounts about biotech’s promise and perils.
Ethical Issues of Human Genetic Databases by Bernice Elger Pdf
Following the boom in population databases in recent years there has been sustained and intense international debate about political processes and legal and ethical issues surrounding the protection and use of genetic data. As a result, several national and international organizations and committees have published widely differing guidelines and statements concerning genetic databases and biobanks. Ethical Issues of Human Genetic Databases compares the new area of biobanking with the tradition of ethically accepted classical research and highlights the distinctive features of existing databases and guidelines. The volume identifies areas of consensus and controversy while investigating the challenges posed to classical health research ethics by the existence of genetic databases, analyzing the reasons for such varying guidelines. The book will be essential to academics, biobankers, policy-makers and researchers in the field of medical ethics.
Genetic Dissection of Complex Traits by D.C. Rao,C. Charles Gu Pdf
The field of genetics is rapidly evolving and new medical breakthroughs are occuring as a result of advances in knowledge of genetics. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. * Five sections on the latest advances in complex traits * Methods for testing with ethical, legal, and social implications * Hot topics include discussions on systems biology approach to drug discovery; using comparative genomics for detecting human disease genes; computationally intensive challenges, and more
Biobanking of Human Biospecimens by Pierre Hainaut,Jim Vaught,Kurt Zatloukal,Markus Pasterk Pdf
Over the past 25 years, biobanks of human specimens have become a cornerstone for research on human health and have empowered the “omics “revolution that characterizes biomedical science in the XXIst Century. Today, biobanking of human specimens is a critical component of the interface between clinical practice and translational research, supporting the discovery and validation of new biomarkers of disease etiology, risk, early detection, diagnosis, prognosis, prediction and relapse. With the development of personalized medicine, biobanking of cryopreserved specimens has become standard practice in order to investigate genetic, transcriptomic, proteomic, metabolomics and immunological biomarkers useful to inform caregivers for therapeutic decisions. Data generated from biobanked specimens represent a rapidly growing and highly valuable resource, participating in the emergence of Big Data Medicine. With the development of large computing capabilities and artificial intelligence, data associated with biobanked specimens constitute a unique resource for the discovery and validation of new biomarkers and therapeutically actionable targets. Interconnecting, interoperating and sharing this data have become major issues for national health systems, raising enormous stakes as well as major societal, legal and cybersecurity challenges in terms of compliance with the protection of personal sensitive information. This book project is the second part of an initiative launched in 2012 to produce a published corpus of knowledge encompassing all aspects of human biobanking as a central practice for research and medicine. The first volume, published in 2017, is entitled: Human Biobanking: Principles and Practice. This first volume compiled a series of high level contributions overseeing the main developments that carried the progression of human biobanking as a research and biotechnological field over the past two decades. This new book project will constitute de facto Volume 2 of the same initiative, under the title: Biobanking of Human Biospecimens: lessons from 25 years of biobanking experience. Hence, the two volumes will share the same generic title (Biobanking of Human Biospecimens), with different subtitles, making clear that the two volumes are interrelated while highlighting their specificities in terms of what they actually cover. As a result, the two books are “twins” but can also be used independently of each other. The overarching aim of the two volumes of Biobanking of Human Biospecimens is to provide a published “one-stop shop” for state-of-the-art information on what constitutes the field of human biobanking, from conception of a biobank, standard operating procedures, ethical and societal aspects, governance, networking, interoperability and economic sustainability. This inclusive publication concept meets the needs of a vast readership, including scientists, doctors and technical staffs who are directly involved in biobanking operations, scientists in other disciplines that heavily rely on biobanking (such as genomics or proteomics), stakeholders and policy makers, and of course students for whom biobanking is becoming an important part of the training curriculum. So far, there has been a lack of major textbooks on biobanking. Documentation for biobanking is widely available through numerous publications, regulatory documents published by International or Governmental Agencies, and sets of recommendations essentially accessible through the Internet. However, it is difficult to access a single, top-of-the shelf reference that provides at a glance a large coverage of all aspects of human biobanking. Fulfilling this need is the main origin of the concept for this back-to-back publication project. To our knowledge, there is currently no other publication project with the same breath and scope as this one in the field of biobanking.
Author : Peter A. Humphrey,Louis P. Dehner,John D. Pfeifer Publisher : Lippincott Williams & Wilkins Page : 1001 pages File Size : 41,8 Mb Release : 2012-05-28 Category : Medical ISBN : 9781451114362
The Washington Manual of Rheumatology Subspecialty Consult by Peter A. Humphrey,Louis P. Dehner,John D. Pfeifer Pdf
"The aim of this book is to provide a practical manual that is helpful to pathologists and residents in the daily practice of surgical pathology. The text encompasses all anatomic sites in the human body. Each chapter covers tissue handling, gross examination, gross dissection and diagnosis, processing, slide preparation, microscopic diagnosis, special studies, and diagnostic reporting. The format of the book would be modeled after the Washington Manuals for other specialties (such as Medical Therapeutics, Oncology, and Surgery)"--Provided by publisher.
The National Bioethics Advisory Commission by Elisa Eiseman Pdf
The National Bioethics Advisory Commission (NBAC) was established in 1995 to advise various government entities on issues arising from research on human biology and behavior. During its five-year tenure, NBAC submitted six reports to the White House containing 120 recommendations on several complex bioethical issues including the cloning of human beings and embryonic stem cell research. This study assesses NBAC's contribution to policymaking by tracking the response to NBAC's recommendations from the president, Congress, government, societies and foundations, other countries, and international groups.
Stem Cell Century by Russell Korobkin,Stephen R. Munzer Pdf
"Stem Cell Century provides a very clear analysis of the policy issues around cloning and stem cells in biomedicine, on the basis of a sound scientific understanding of the underlying biology." Ian Wilmut, director, Edinburgh University Centre for Regenerative Medicine, and creator of "Dolly" the lamb, the world's first cloned mammal. From the bookjacket.
Handbook of Health Social Work by Sarah Gehlert,Teri Browne Pdf
Praise for HANDBOOK of HEALTH SOCIAL WORK SECOND EDITION "Handbook of Health Social Work, Second Edition is a crucial addition for seasoned practitioners' libraries, as well as an essential foundation for fledgling social workers ready to enter health as a practice and research area." –From the Foreword by Suzanne Heurtin-Roberts, U.S. Department of Health and Human Services "The book's strengths include the high quality of writing and the expertise of its contributors. It covers the field of health social work in significant depth and is sure to leave readers well informed." –Mary Sormanti, PhD, MSW, Associate Professor of Professional Practice, Columbia University School of Social Work "Quite simply, this is the definitive volume for health and social work. In this second edition, Gehlert and Browne and their expert contributors have confidently managed to keep pace with current theory and empirical research across a wide range of subject matter that will be of interest to practitioners, educators, and researchers." –Michael Vaughn, PhD, Assistant Professor, School of Social Work, School of Public Health, and Department of Public Policy Studies, Saint Louis University Thoroughly revised and updated, the only comprehensive handbook of its kind covering the diverse field of health social work Now in its Second Edition, Handbook of Health Social Work provides a comprehensive and evidence-based overview of contemporary social work practice in health care. Written from a wellness perspective, the chapters cover practice and research areas ranging from chronic disorders to infectious disease, from physical to mental disorders, and all areas in between. An excellent resource preparing social workers for the present and future challenges of practice in the field of health care, the Handbook of Health Social Work, Second Edition features discussion on: New trends in social work and health care, including genetics, transdisciplinary care, as well as national and state changes in policy Health social work and children The wide array of roles performed by social workers in health-care settings Ethical issues and decision making in a variety of arenas Understanding of community factors in health social work Edited by two respected leaders in the field of health social work, this second edition includes contributions from a diverse team of notable experts, researchers, and scholars addressing multiple theoretical foundations, models, issues, and dilemmas for the social worker in health care. The resulting resource offers both a foundation for social work practice in health care and a guide for strategy, policy, and program development in proactive and actionable terms.
Tietz Textbook of Laboratory Medicine - E-Book by Nader Rifai Pdf
Use THE definitive reference for laboratory medicine and clinical pathology! Tietz Textbook of Laboratory Medicine, 7th Edition provides the guidance necessary to select, perform, and evaluate the results of new and established laboratory tests. Comprehensive coverage includes the latest advances in topics such as clinical chemistry, genetic metabolic disorders, molecular diagnostics, hematology and coagulation, clinical microbiology, transfusion medicine, and clinical immunology. From a team of expert contributors led by Nader Rifai, this reference includes access to wide-ranging online resources on Expert Consult — featuring the comprehensive product with fully searchable text, regular content updates, animations, podcasts, over 1300 clinical case studies, lecture series, and more. Authoritative, current content helps you perform tests in a cost-effective, timely, and efficient manner; provides expertise in managing clinical laboratory needs; and shows how to be responsive to an ever-changing environment. Current guidelines help you select, perform, and evaluate the results of new and established laboratory tests. Expert, internationally recognized chapter authors present guidelines representing different practices and points of view. Analytical criteria focus on the medical usefulness of laboratory procedures. Use of standard and international units of measure makes this text appropriate for any user, anywhere in the world. Expert Consult provides the entire text as a fully searchable eBook, and includes regular content updates, animations, podcasts, more than 1300 clinical case studies, over 2500 multiple-choice questions, a lecture series, and more. NEW! 19 additional chapters highlight various specialties throughout laboratory medicine. NEW! Updated, peer-reviewed content provides the most current information possible. NEW! The largest-ever compilation of clinical cases in laboratory medicine is included on Expert Consult. NEW! Over 100 adaptive learning courses on Expert Consult offer the opportunity for personalized education.
Genetic Databases by Oonagh Corrigan,Richard Tutton Pdf
Genetic Databases offers a timely analysis of the underlying tensions, contradictions and limitations of the current regulatory frameworks for, and policy debates about, genetic databases. Drawing on original empirical research and theoretical debates in the fields of sociology, anthropology and legal studies, the contributors to this book challenge the prevailing orthodoxy of informed consent and explore the relationship between personal privacy and the public good. They also consider the multiple meanings attached to human tissue and the role of public consultations and commercial involvement in the creation and use of genetic databases. The authors argue that policy and regulatory frameworks produce a representation of participation that is often at odds with the experiences and understandings of those taking part. The findings present a serious challenge for public policy to provide mechanisms to safeguard the welfare of individuals participating in genetic databases.
