Health Effects Of Lead Exposure

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Lead Toxicity

Author : Sarah E. Royce
Publisher : Unknown
Page : 60 pages
File Size : 50,9 Mb
Release : 2000
Category : Lead
ISBN : UOM:39015051606617

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Lead Toxicity by Sarah E. Royce Pdf

Potential Health Risks to DOD Firing-Range Personnel from Recurrent Lead Exposure

Author : National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on Toxicology,Committee on Potential Health Risks from Recurrent Lead Exposure of DOD Firing Range Personnel
Publisher : National Academies Press
Page : 199 pages
File Size : 51,5 Mb
Release : 2013-04-20
Category : Medical
ISBN : 9780309267366

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Potential Health Risks to DOD Firing-Range Personnel from Recurrent Lead Exposure by National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on Toxicology,Committee on Potential Health Risks from Recurrent Lead Exposure of DOD Firing Range Personnel Pdf

Lead is a ubiquitous metal in the environment, and its adverse effects on human health are well documented. Lead interacts at multiple cellular sites and can alter protein function in part through binding to amino acid sulfhydryl and carboxyl groups on a wide variety of structural and functional proteins. In addition, lead mimics calcium and other divalent cations, and it induces the increased production of cytotoxic reactive oxygen species. Adverse effects associated with lead exposure can be observed in multiple body systems, including the nervous, cardiovascular, renal, hematologic, immunologic, and reproductive systems. Lead exposure is also known to induce adverse developmental effects in utero and in the developing neonate. Lead poses an occupational health hazard, and the Occupational Safety and Health Administration (OSHA) developed a lead standard for general industry that regulates many workplace exposures to this metal. The standard was promulgated in 1978 and encompasses several approaches for reducing exposure to lead, including the establishment of a permissible exposure limit (PEL) of 50 μg/m3 in air (an 8-hour time-weighted average [TWA]), exposure guidelines for instituting medical surveillance, guidelines for removal from and return to work, and other risk-management strategies. An action level of 30 μg/m3 (an 8-hour TWA) for lead was established to trigger medical surveillance in employees exposed above that level for more than 30 days per year. Another provision is that any employee who has a blood lead level (BLL) of 60 μg/dL or higher or three consecutive BLLs averaging 50 μg/dL or higher must be removed from work involving lead exposure. An employee may resume work associated with lead exposure only after two BLLs are lower than 40 μg/dL. Thus, maintaining BLLs lower than 40 μg/dL was judged by OSHA to protect workers from adverse health effects. The OSHA standard also includes a recommendation that BLLs of workers who are planning a pregnancy be under 30μg/dL. In light of knowledge about the hazards posed by occupational lead exposure, the Department of Defense (DOD) asked the National Research Council to evaluate potential health risks from recurrent lead exposure of firing-range personnel. Specifically, DOD asked the National Research Council to determine whether current exposure standards for lead on DOD firing ranges protect its workers adequately.The committee also considered measures of cumulative lead dose. Potential Health Risks to DOD Firing-Range Personnel from Recurrent Lead Exposure will help to inform decisions about setting new air exposure limits for lead on firing ranges, about whether to implement limits for surface contamination, and about how to design lead-surveillance programs for range personnel appropriately.

Measuring Lead Exposure in Infants, Children, and Other Sensitive Populations

Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Measuring Lead in Critical Populations
Publisher : National Academies Press
Page : 356 pages
File Size : 42,6 Mb
Release : 1993-02-01
Category : Science
ISBN : 9780309049276

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Measuring Lead Exposure in Infants, Children, and Other Sensitive Populations by National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Measuring Lead in Critical Populations Pdf

Lead is a ubiquitous toxic agent that is especially damaging to the young child and the developing fetus. Unlike many environmental health risks, the risks associated with lead are no longer theoretical but have been observed for many years. Indeed, the first regulation of lead in paint was enacted in the 1920s. Currently, because of growing evidence of lead toxicity at lower concentrations, the U.S. Centers for Disease Control and Prevention recently lowered its lead-exposure guideline to 10 ug/dl lead in blood from 25 ug/dl. Measuring Lead Exposure in Infants, Children, and Other Sensitive Populations addresses the public health concern about the logistics and feasibility of lead screening in infants and children at such low concentrations. This book will serve as the basis for all U.S. Public Health Service activities and for all state and local programs in monitoring lead.

A Small Dose of Toxicology

Author : Steven G. Gilbert
Publisher : CRC Press
Page : 279 pages
File Size : 46,7 Mb
Release : 2004-02-18
Category : Medical
ISBN : 9780203461730

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A Small Dose of Toxicology by Steven G. Gilbert Pdf

Everyday, we come into contact with many relatively harmless substances that could, at certain concentrations, be toxic. This applies not only to obvious candidates such as asbestos, lead, and gasoline, but also to compounds such as caffeine and headache tablets. While the field of toxicology has numerous texts devoted to aspects of biology, chemis

Health Effects of Lead

Author : Commission on Lead in the Environment
Publisher : Royal Society of Canada, Commission on Lead in the Environment
Page : 536 pages
File Size : 48,7 Mb
Release : 1986
Category : Lead
ISBN : UCSD:31822002286755

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Health Effects of Lead by Commission on Lead in the Environment Pdf

Toxicological Profile for Lead

Author : Anonim
Publisher : Unknown
Page : 584 pages
File Size : 53,6 Mb
Release : 2007
Category : Lead
ISBN : UOM:39015074067839

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Toxicological Profile for Lead by Anonim Pdf

Lead Poisoning

Author : Joseph J. Breen,Cindy R. Stroup
Publisher : CRC Press
Page : 304 pages
File Size : 55,8 Mb
Release : 1995-03-23
Category : Science
ISBN : 1566701139

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Lead Poisoning by Joseph J. Breen,Cindy R. Stroup Pdf

Lead Poisoning discusses one of the most critical and preventable environmentally induced illnesses. The actual toll lead poisoning takes on society cannot be measured fully due to the "silent" nature of health effects, such as subtle intellectual deficits and neurological damage, caused by chronic low-level exposures. This book covers every major topic on the subject, including lead poisoning in children, sources of contamination, state-of-the-art sampling and analytical measurement methods, the newest studies on low-cost abatement methods, and much more. This reference is the most comprehensive presentation of issues currently available under one cover. The text is divided into three major parts. Part I provides insights from studies assessing lead exposures from paint, dust, soil, and lead battery recycling operations. The second part is a unique collection of strategic federal policy statements from the U.S. EPA, HUD, and HEW-CDC. It details the National Implementation Plan as well as a local government's efforts to provide low-cost effective risk communication and public outreach to the community. The next part offers seven chapters on analytical issues in the measurement of lead in blood, paint, dust, and soils. Part IV, Sampling Methods and Statistical Issues, rounds out the technical portion of the volume. The relationships among lead levels in biological and environmental media are investigated and the interpretive problems discussed. The use of multi-element analysis of environmental samples as an approach to investigate sources is described. The book finishes with its most unique feature-OPPT's Check Our Kids for Lead Program, one organization's effort to empower its employees to make a personal difference in confronting the problem of lead poisoning in children. The Program serves as a model for other government organizations (federal, state, and local), university and community organizations, and corporations to educate them and take personal and corporate responsibility for addressing this important and environmental health problem.

Lead Pollution

Author : Roger Harrison
Publisher : Springer Science & Business Media
Page : 152 pages
File Size : 40,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461597056

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Lead Pollution by Roger Harrison Pdf

At the time of writing, the topic of lead pollution is the subject of an intense and sometimes heated debate. The argument centres upon possible adverse health effects arising from exposure of children to current environmental levels of lead. Such arguments now appear little closer to resolution than they did five years ago, although the development of ever more sophisticated biochemical and epidemiological techniques may eventually provide an answer. Over the past five to ten years, as the general public has become aware of the lead issue, pressure has been put upon governments to limit emissions of lead, and hence limit or reduce the exposure of the population to the metal. Govern ments and governmental agencies have responded in several ways, varying between those who prefer to take little or no action on the basis that they see no cause for concern, and those who have taken firm action after concluding that the scientific and medical evidence warrants this approach. Any effective control strategy for lead requires knowledge of the sources of environmental exposure and an understanding of the pathways of this metal in the environment. This book aims to provide such information and to explain the methods available for limiting emissions of lead from the most important sources. To put this information in context a chapter on the routes of human exposure to lead and the health effects is included.

Lead; Airborne Lead in Perspective

Author : National Research Council (U.S.). Committee on Biologic Effects of Atmospheric Pollutants
Publisher : Unknown
Page : 348 pages
File Size : 46,9 Mb
Release : 1972
Category : Medical
ISBN : NAP:13433

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Lead; Airborne Lead in Perspective by National Research Council (U.S.). Committee on Biologic Effects of Atmospheric Pollutants Pdf

Lead and Human Health: An Update

Author : Daland R. Juberg
Publisher : Am Cncl on Science, Health
Page : 64 pages
File Size : 40,5 Mb
Release : 1997
Category : Lead
ISBN : 8210379456XXX

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Lead and Human Health: An Update by Daland R. Juberg Pdf

Lead: Its Effects on Environment and Health

Author : Astrid Sigel,Helmut Sigel,Roland K.O. Sigel
Publisher : Walter de Gruyter GmbH & Co KG
Page : 633 pages
File Size : 43,5 Mb
Release : 2017-04-10
Category : Science
ISBN : 9783110433012

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Lead: Its Effects on Environment and Health by Astrid Sigel,Helmut Sigel,Roland K.O. Sigel Pdf

Volume 17, entitled Lead: Its Effects on Environment and Health of the series Metal Ions in Life Sciences centers on the interrelations between biosystems and lead. The book provides an up-to-date review of the bioinorganic chemistry of this metal and its ions; it covers the biogeochemistry of lead, its use (not only as gasoline additive) and anthropogenic release into the environment, its cycling and speciation in the atmosphere, in waters, soils, and sediments, and also in mammalian organs. The analytical tools to determine and to quantify this toxic element in blood, saliva, urine, hair, etc. are described. The properties of lead(II) complexes formed with amino acids, peptides, proteins (including metallothioneins), nucleobases, nucleotides, nucleic acids, and other ligands of biological relevance are summarized for the solid state and for aqueous solutions as well. All this is important for obtaining a coherent picture on the properties of lead, its effects on plants and toxic actions on mammalian organs. This and more is treated in an authoritative and timely manner in the 16 stimulating chapters of Volume 17, which are written by 36 internationally recognized experts from 13 nations. The impact of this recently again vibrant research area is manifested in nearly 2000 references, over 50 tables and more than 100 illustrations (half in color). Lead: Its Effects on Environment and Health is an essential resource for scientists working in the wide range from material sciences, inorganic biochemistry all the way through to medicine including the clinic ... not forgetting that it also provides excellent information for teaching.

Environmental Medicine

Author : Institute of Medicine,Committee on Curriculum Development in Environmental Medicine
Publisher : National Academies Press
Page : 988 pages
File Size : 50,5 Mb
Release : 1995-05-28
Category : Medical
ISBN : 9780309051408

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Environmental Medicine by Institute of Medicine,Committee on Curriculum Development in Environmental Medicine Pdf

People are increasingly concerned about potential environmental health hazards and often ask their physicians questions such as: "Is the tap water safe to drink?" "Is it safe to live near power lines?" Unfortunately, physicians often lack the information and training related to environmental health risks needed to answer such questions. This book discusses six competency based learning objectives for all medical school students, discusses the relevance of environmental health to specific courses and clerkships, and demonstrates how to integrate environmental health into the curriculum through published case studies, some of which are included in one of the book's three appendices. Also included is a guide on where to obtain additional information for treatment, referral, and follow-up for diseases with possible environmental and/or occupational origins.

Lead Wars

Author : Gerald Markowitz,David Rosner
Publisher : Univ of California Press
Page : 322 pages
File Size : 54,9 Mb
Release : 2014-08-15
Category : History
ISBN : 9780520283930

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Lead Wars by Gerald Markowitz,David Rosner Pdf

In this incisive examination of lead poisoning during the past half century, Gerald Markowitz and David Rosner focus on one of the most contentious and bitter battles in the history of public health. Lead Wars details how the nature of the epidemic has changed and highlights the dilemmas public health agencies face today in terms of prevention strategies and chronic illness linked to low levels of toxic exposure. The authors use the opinion by Maryland’s Court of Appeals—which considered whether researchers at Johns Hopkins University’s prestigious Kennedy Krieger Institute (KKI) engaged in unethical research on 108 African-American children—as a springboard to ask fundamental questions about the practice and future of public health. Lead Wars chronicles the obstacles faced by public health workers in the conservative, pro-business, anti-regulatory climate that took off in the Reagan years and that stymied efforts to eliminate lead from the environments and the bodies of American children.

Health Effects of Lead Exposure

Author : Alberta. Medical Services Branch
Publisher : Unknown
Page : 128 pages
File Size : 55,6 Mb
Release : 1987
Category : Electronic
ISBN : OCLC:148848873

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Health Effects of Lead Exposure by Alberta. Medical Services Branch Pdf