Hematopoietic Stem Cell Transplantation Research Advances

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Hematopoietic Stem Cell Transplantation Research Advances

Karl B. Neumann
Hematopoietic Stem Cell Transplantation Research Advances Book PDF

Author : Karl B. Neumann
Publisher : Nova Publishers
Page : 262 pages
File Size : 42,8 Mb
Release : 2008
Category : Hematopoietic stem cells
ISBN : 1604560428

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Hematopoietic Stem Cell Transplantation Research Advances by Karl B. Neumann Pdf

Hematopoietic stem cell transplantation (HSCT) is the transplantation of blood stem cells derived from the bone marrow (that is, bone marrow transplantation) or blood. Stem cell transplantation is a medical procedure in the fields of haematology and oncology, most often performed for people with diseases of the blood, bone marrow, or certain types of cancer. Stem cell transplantation was pioneered using bone-marrow-derived stem cells by a team at the Fred Hutchinson Cancer Research Center from the 1950s through the 1970s led by E. Donnall Thomas, whose work was later recognised with a Nobel Prize in Physiology and Medicine. Thomas' work showed that bone marrow cells infused intravenously could repopulate the bone marrow and produce new blood cells. His work also reduced the likelihood of developing a life-threatening complication called Graft-versus-host disease. With the availability of the stem cell growth factors GM-CSF and G-CSF, most hematopoeitic stem cell transplantation procedures are now performed using stem cells collected from the peripheral blood, rather than from the bone marrow. Collecting stem cells provides a bigger graft, and does not require that the donor be subjected to general anaesthesia to collect the graft. Hematopoeitic stem cell transplantation remains a risky procedure with many possible complications; it has always been reserved for patients with life-threatening diseases. This book presents recent leading research in the field.

Advances in Hematopoietic Stem Cell Research

Rosana Pelayo
Advances in Hematopoietic Stem Cell Research Book PDF

Author : Rosana Pelayo
Publisher : BoD – Books on Demand
Page : 480 pages
File Size : 45,7 Mb
Release : 2012-01-27
Category : Science
ISBN : 9789533079301

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Advances in Hematopoietic Stem Cell Research by Rosana Pelayo Pdf

This book provides a comprehensive overview in our understanding of the biology and therapeutic potential of hematopoietic stem cells, and is aimed at those engaged in stem cell research: undergraduate and postgraduate science students, investigators and clinicians. Starting from fundamental principles in hematopoiesis, Advances in Hematopoietic Stem Cell Research assemble a wealth of information relevant to central mechanisms that may regulate differentiation, and expansion of hematopoietic stem cells in normal conditions and during disease.

Advances in Transplantation Research and Application: 2013 Edition

Anonim
Advances in Transplantation Research and Application 2013 Edition Book PDF

Author : Anonim
Publisher : ScholarlyEditions
Page : 283 pages
File Size : 43,6 Mb
Release : 2013-06-21
Category : Medical
ISBN : 9781481672108

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Advances in Transplantation Research and Application: 2013 Edition by Anonim Pdf

Advances in Transplantation Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Cell Transplantation. The editors have built Advances in Transplantation Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cell Transplantation in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Transplantation Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Advances in Allogeneic Hematopoietic Stem Cell Transplantation

Richard K. Burt,Mary M. Brush
Advances in Allogeneic Hematopoietic Stem Cell Transplantation Book PDF

Author : Richard K. Burt,Mary M. Brush
Publisher : Springer
Page : 419 pages
File Size : 40,8 Mb
Release : 2012-11-28
Category : Medical
ISBN : 9781461549871

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Advances in Allogeneic Hematopoietic Stem Cell Transplantation by Richard K. Burt,Mary M. Brush Pdf

The field of hematopoietic stem cell transplantation is rapidly evolving. Realization that hematopoietic stem cells give rise to the immune compartment has resulted in clinical trials of hematopoietic stem cell transplantation for patients with autoimmune diseases. Allogeneic hematopoietic transplants are a form of adoptive immunotherapy resulting in beneficial graft versus tumor effects. Large numbers of hematopoietic cells can be collected with ease. Therefore, a renewable source of cells for ex vivo genetic manipulations is readily available. Multiple trials combining hematopoietic transplants and gene therapy are in progress. One such application is the infusion of allogeneic lymphocytes containing a suicide gene to abort graft versus host disease. Hematopoietic stem cell transplantation is in reality the clinical and practical application of cellular therapy. Hematopoietic transplant physicians are by design or by practical application evolving into cell and gene therapy specialists. The excitement and enthusiasm in hematopoietic transplantation is that it offers a door to the future. A future not of drugs or titrating poisonous chemotherapy but rather of cellular and gene therapy. 1 ALLOGENEIC PERIPHERAL BLOOD STEM CELL TRANSPLANTATION FOR HEMATOLOGIC DISEASES Martin Korbling University o/Texas MD. Anderson Cancer Center, Houston, Texas 77030 INTRODUCTION Circulating hematopoietic stem cells have emerged as an alternative to bone marrow (BM) stem cells for allografting. For many years the reconstitutive potential of circulating stem cells was questioned; peripheral blood stem cells (PBSC) were even characterized a waste product (1).

Advances in Stem Cell Transplantation Research and Application: 2012 Edition

Anonim
Advances in Stem Cell Transplantation Research and Application 2012 Edition Book PDF

Author : Anonim
Publisher : ScholarlyEditions
Page : 28 pages
File Size : 52,9 Mb
Release : 2012-12-26
Category : Medical
ISBN : 9781481636087

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Advances in Stem Cell Transplantation Research and Application: 2012 Edition by Anonim Pdf

Advances in Stem Cell Transplantation Research and Application / 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Stem Cell Transplantation in a compact format. The editors have built Advances in Stem Cell Transplantation Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Stem Cell Transplantation in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Stem Cell Transplantation Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Advances in Transplantation Research and Application: 2012 Edition

Anonim
Advances in Transplantation Research and Application 2012 Edition Book PDF

Author : Anonim
Publisher : ScholarlyEditions
Page : 547 pages
File Size : 52,5 Mb
Release : 2012-12-26
Category : Medical
ISBN : 9781464992513

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Advances in Transplantation Research and Application: 2012 Edition by Anonim Pdf

Advances in Transplantation Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Transplantation. The editors have built Advances in Transplantation Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Transplantation in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Transplantation Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation

Gerard Socie,Robert Zeiser,Bruce R. Blazar
Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation Book PDF

Author : Gerard Socie,Robert Zeiser,Bruce R. Blazar
Publisher : Academic Press
Page : 430 pages
File Size : 55,7 Mb
Release : 2018-11-22
Category : Science
ISBN : 9780128134399

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Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation by Gerard Socie,Robert Zeiser,Bruce R. Blazar Pdf

Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation: Models in Discovery and Translation, Second Edition once again provides clinical and scientific researchers with a deep understanding of the current research in this field and the implications for translational practice. By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemia effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes, and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future. The second edition is fully revised and includes new chapters on microbiome, metabolism, kinase targets, micro-RNA and mRNA regulatory mechanisms, signaling pathways in GVHD, innate lymphoid system development, recovery and function in GVHD, genetically engineered T-cell therapies, immune system engagers for GVHD and graft-versus-tumor, and hematopoietic cell transplant for tolerance induction in solid organ grafts. Brings together perspectives from leading laboratories and clinical research groups to highlight advances from bench to the bedside Guides readers through the caveats that must be considered when drawing conclusions from studies with animal models before correlating to clinical allogeneic hematopoietic stem cell transplantation (HSCT) scenarios Categorizes the published advances in various aspects of immune biology of allogeneic HSCT to illustrate opportunities for clinical applications

Advances in Hematopoietic Stem Cell Transplantation and Molecular Therapy

Rainer Haas,Ralf Kronenwett,Georg Sczakiel
Advances in Hematopoietic Stem Cell Transplantation and Molecular Therapy Book PDF

Author : Rainer Haas,Ralf Kronenwett,Georg Sczakiel
Publisher : Springer Science & Business Media
Page : 159 pages
File Size : 51,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642468360

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Advances in Hematopoietic Stem Cell Transplantation and Molecular Therapy by Rainer Haas,Ralf Kronenwett,Georg Sczakiel Pdf

Blood stem cell transplantation has become an established therapeutic option in the treatment of malignant diseases. At the same time molecular therapeutic approaches (i.e. gene therapy) are promising alternatives to the classical treatment of cancer. The proceedings give an overview of the biology of hematopoietic progenitor cells, peripheral stem cell transplantation in patients with hematological malignancies, recent developments in molecular diagnosis and gene therapeutic concepts, and show that successful future developments require cooperative research connecting basic science with clinical application.

Hematopoietic Stem Cell Transplantation

Michael R. Bishop
Hematopoietic Stem Cell Transplantation Book PDF

Author : Michael R. Bishop
Publisher : Springer Science & Business Media
Page : 592 pages
File Size : 55,6 Mb
Release : 2009-09-25
Category : Medical
ISBN : 9780387785806

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Hematopoietic Stem Cell Transplantation by Michael R. Bishop Pdf

The dogmas of the quiet past are inadequate to the stormy present. The occasion is piled high with difficulty, and we must rise with the occasion. As our case is new, so we must think anew and act anew. Abraham Lincoln, 1862 When I came across this quote, it made me recall my first participation at an international meeting on bone marrow transplantation, at a time when this was the only term that was used to describe the field. During a particular session there was a presentation on the use of peripheral blood as the sole source of stem cells for transplantation, and a member of the audience rose to state that it was medically unethical to consider such treatment, as it certainly could not contain stem cells. Now nearly twenty years later, peripheral blood is the predominant source of stem cells used for hematopoietic stem cell transplantation. In the same period of time there have been several other dogmatic opinions, which permeate all of medicine, that have come and gone in the field of hematopoietic stem cell transplantation, and will continue to do so with advancements from basic and clinical research. It is within this context that the format of this book was devised. Traditionally reviews on specific topics related to hematopoietic stem cell transplantation reflect the views of a single author or a research group.

Advances in Stem Cell Transplantation Research and Application: 2011 Edition

Anonim
Advances in Stem Cell Transplantation Research and Application 2011 Edition Book PDF

Author : Anonim
Publisher : ScholarlyEditions
Page : 21 pages
File Size : 52,5 Mb
Release : 2012-01-09
Category : Science
ISBN : 9781464957574

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Advances in Stem Cell Transplantation Research and Application: 2011 Edition by Anonim Pdf

Advances in Stem Cell Transplantation Research and Application: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Stem Cell Transplantation in a compact format. The editors have built Advances in Stem Cell Transplantation Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Stem Cell Transplantation in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Stem Cell Transplantation Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Hematopoietic Stem Cell Transplantation

Anthony D. Ho,Rainer Haas,Richard E. Champlin
Hematopoietic Stem Cell Transplantation Book PDF

Author : Anthony D. Ho,Rainer Haas,Richard E. Champlin
Publisher : CRC Press
Page : 610 pages
File Size : 52,6 Mb
Release : 2000-07-25
Category : Medical
ISBN : 9780824741815

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Hematopoietic Stem Cell Transplantation by Anthony D. Ho,Rainer Haas,Richard E. Champlin Pdf

This book integrates recent advances in molecular and cell biology of hematopoietic stem cells (HSC) with developments in clinical research in stem cell-based therapy-providing an up-to-date review of novel cytokines and cellular components; animal models; cell preparation, selection, and collection; minimal residual disease and purging; expansion

New Advances in Stem Cell Transplantation

Taner Demirer
New Advances in Stem Cell Transplantation Book PDF

Author : Taner Demirer
Publisher : BoD – Books on Demand
Page : 598 pages
File Size : 44,9 Mb
Release : 2012-02-24
Category : Science
ISBN : 9789535100133

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New Advances in Stem Cell Transplantation by Taner Demirer Pdf

This book documents the increased number of stem cell-related research, clinical applications, and views for the future. The book covers a wide range of issues in cell-based therapy and regenerative medicine, and includes clinical and preclinical chapters from the respected authors involved with stem cell studies and research from around the world. It complements and extends the basics of stem cell physiology, hematopoietic stem cells, issues related to clinical problems, tissue typing, cryopreservation, dendritic cells, mesenchymal cells, neuroscience, endovascular cells and other tissues. In addition, tissue engineering that employs novel methods with stem cells is explored. Clearly, the continued use of biomedical engineering will depend heavily on stem cells, and this book is well positioned to provide comprehensive coverage of these developments.

Advances in Cell Transplantation Research and Application: 2011 Edition

Anonim
Advances in Cell Transplantation Research and Application 2011 Edition Book PDF

Author : Anonim
Publisher : ScholarlyEditions
Page : 25 pages
File Size : 41,5 Mb
Release : 2012-01-09
Category : Science
ISBN : 9781464957420

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Advances in Cell Transplantation Research and Application: 2011 Edition by Anonim Pdf

Advances in Cell Transplantation Research and Application: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Cell Transplantation in a compact format. The editors have built Advances in Cell Transplantation Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cell Transplantation in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Cell Transplantation Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Advances in Stem Cell Research

Hossein Baharvand,Nasser Aghdami
Advances in Stem Cell Research Book PDF

Author : Hossein Baharvand,Nasser Aghdami
Publisher : Springer Science & Business Media
Page : 398 pages
File Size : 53,7 Mb
Release : 2012-05-26
Category : Science
ISBN : 9781617799402

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Advances in Stem Cell Research by Hossein Baharvand,Nasser Aghdami Pdf

Advances in Stem Cell Research discusses recent advances in stem cell science, including therapeutic applications. This volume covers such topics as biomanufacturing iPS cells for therapeutic applications, techniques for controlling stem cell fate decisions, as well as current basic research in such areas as germ line stem cells, genomics and proteomics in stem cell research. It is a useful book for biology and clinical scientists, especially young investigators and stem cell biology students who are newly entering the world of stem cells research. The editors hope that the new knowledge and research outlined in this book will help contribute to new therapies for a wide variety of diseases that presently afflict humanity.

Advances in Hematopoietic System Research and Application: 2013 Edition

Anonim
Advances in Hematopoietic System Research and Application 2013 Edition Book PDF

Author : Anonim
Publisher : ScholarlyEditions
Page : 272 pages
File Size : 43,8 Mb
Release : 2013-06-21
Category : Medical
ISBN : 9781481670623

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Advances in Hematopoietic System Research and Application: 2013 Edition by Anonim Pdf

Advances in Hematopoietic System Research and Application: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about ZZZAdditional Research in a concise format. The editors have built Advances in Hematopoietic System Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ZZZAdditional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Hematopoietic System Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.