History Of Organ And Cell Transplantation

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History Of Organ And Cell Transplantation

Author : Nadey S Hakim,Vassilios E Papalois
Publisher : World Scientific
Page : 464 pages
File Size : 46,8 Mb
Release : 2003-03-12
Category : Medical
ISBN : 9781783261802

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History Of Organ And Cell Transplantation by Nadey S Hakim,Vassilios E Papalois Pdf

Organ transplantation is the greatest therapeutic advancement of the second half of the 20th century. Of all medical specialities, the pioneers of transplantation make up the largest number of experts awarded with, or nominated for the Nobel Prize.Over the years, transplantation has fascinated the scientific community as well as the general public for a variety of reasons:• The development of transplantation has involved almost all medical specialities. In the history of medicine, there is perhaps no other example of such extensive co-operation and exchange of knowledge and experience among basic scientists, surgeons and physicians in achieving a common goal.• The progress of transplantation has forced doctors to “rewrite” medical textbooks dealing with a great spectrum of post-transplantation issues, such as the physiology of transplanted organs, the recurrence of initial disease in the transplanted organs, and the complications arising from immunosuppressive drugs, infectious diseases and cancer. Other issues raised concern maternity, child development, geriatric medicine and ethical issues.However, the history of this amazing field of modern medicine has never been thoroughly reported in a detailed textbook. History of Organ and Cell Transplantation covers this area of modern literature. It includes a foreword written by Lady Jean Medawar who is the wife of the late Sir Peter Medawar, Nobel Prize winner and first president of the International Transplantation Society.

The Origins of Organ Transplantation

Author : Thomas Schlich
Publisher : University Rochester Press
Page : 368 pages
File Size : 49,8 Mb
Release : 2010
Category : History
ISBN : 9781580463539

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The Origins of Organ Transplantation by Thomas Schlich Pdf

This book investigates a crucial-but forgotten-episode in the history of medicine. In it, Thomas Schlich systematically documents and analyzes the earliest clinical and experimental organ transplant surgeries. In so doing he lays open the historical origins of modern transplantation, offering a new and original analysis of its conceptual basis within a broader historical context. This first comprehensive account of the birth of modern transplant medicine examines how doctors and scientists between 1880 and 1930 developed the technology and rationale for performing surgical organ replacement within the epistemological and social context of experimental university medicine. The clinical application of organ replacement, however, met with formidable obstacles even as the procedure became more widely recognized. Schlich highlights various attempts to overcome these obstacles, including immunological explanations and new technologies of immune suppression, and documents the changes in surgical technique and research standards that led to the temporary abandonment of organ transplantation by the 1930s. Thomas Schlich is professor and Canada Research Chair in the History of Medicine at McGill University.

A History of Organ Transplantation

Author : David Hamilton
Publisher : University of Pittsburgh Pre
Page : 577 pages
File Size : 41,7 Mb
Release : 2013-12-21
Category : Medical
ISBN : 9780822977841

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A History of Organ Transplantation by David Hamilton Pdf

A History of Organ Transplantation is a comprehensive and ambitious exploration of transplant surgery—which, surprisingly, is one of the longest continuous medical endeavors in history. Moreover, no other medical enterprise has had so many multiple interactions with other fields, including biology, ethics, law, government, and technology. Exploring the medical, scientific, and surgical events that led to modern transplant techniques, Hamilton argues that progress in successful transplantation required a unique combination of multiple methods, bold surgical empiricism, and major immunological insights in order for surgeons to develop an understanding of the body's most complex and mysterious mechanisms. Surgical progress was nonlinear, sometimes reverting and sometimes significantly advancing through luck, serendipity, or helpful accidents of nature. The first book of its kind, A History of Organ Transplantation examines the evolution of surgical tissue replacement from classical times to the medieval period to the present day. This well-executed volume will be useful to undergraduates, graduate students, scholars, surgeons, and the general public. Both Western and non-Western experiences as well as folk practices are included.

Introduction to Organ Transplantation

Author : Nadey Hakim
Publisher : World Scientific
Page : 265 pages
File Size : 40,8 Mb
Release : 2012
Category : Medical
ISBN : 9781848168541

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Introduction to Organ Transplantation by Nadey Hakim Pdf

This second edition of the introduction to the field of organ transplantation provides an excellent overview of the tremendous progress made in recent decades, and gives a clear description of the current status of transplant surgery for students and trainees with an interest in this field. It opens with introductory chapters on the history of transplantation and the basic science of immunobiology, and then examines through an organ-based structure the practice of transplantation in each major system, from skin to intestine. There is a 13-year gap between the first and second edition, and this is highlighted in the new collection of chapters of this updated version. This is a timely publication produced in line with the rapidly advancing field of transplantation. The editor, Nadey S Hakim, is a consultant transplant and general surgeon at Imperial College Healthcare NHS Trust, London, England, and has put together this second volume that will serve as an invaluable guide for transplant surgeons as well as trainees.

Organ Transplants

Author : Henry Wouk
Publisher : Cavendish Square Publishing, LLC
Page : 74 pages
File Size : 47,9 Mb
Release : 2013-08-01
Category : Juvenile Nonfiction
ISBN : 9781608705955

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Organ Transplants by Henry Wouk Pdf

Every ten minutes, a new name is added to the ever-growing national organ transplant waiting list. Readers will explore the history of organ transplants and its current state. Readers will learn about how organ donor and registry works, as well as what it's like to be a patient waiting for this life-saving medicine.

The Graft

Author : Edmund O. Lawler
Publisher : Anthem Press
Page : 141 pages
File Size : 53,8 Mb
Release : 2021-08-17
Category : Medical
ISBN : 9781785278365

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The Graft by Edmund O. Lawler Pdf

The first human organ transplant in 1950 at a suburban hospital is the focus of The Graft: How a Pioneering Operation Sparked the Modern Age of Organ Transplants. The book examines the controversies the operation generated and the progress medicine has made in organ transplantation.

Contemporary Bioethics

Author : Mohammed Ali Al-Bar,Hassan Chamsi-Pasha
Publisher : Springer
Page : 267 pages
File Size : 45,7 Mb
Release : 2015-05-27
Category : Medical
ISBN : 9783319184289

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Contemporary Bioethics by Mohammed Ali Al-Bar,Hassan Chamsi-Pasha Pdf

This book discusses the common principles of morality and ethics derived from divinely endowed intuitive reason through the creation of al-fitr' a (nature) and human intellect (al-‘aql). Biomedical topics are presented and ethical issues related to topics such as genetic testing, assisted reproduction and organ transplantation are discussed. Whereas these natural sources are God’s special gifts to human beings, God’s revelation as given to the prophets is the supernatural source of divine guidance through which human communities have been guided at all times through history. The second part of the book concentrates on the objectives of Islamic religious practice – the maqa' sid – which include: Preservation of Faith, Preservation of Life, Preservation of Mind (intellect and reason), Preservation of Progeny (al-nasl) and Preservation of Property. Lastly, the third part of the book discusses selected topical issues, including abortion, assisted reproduction devices, genetics, organ transplantation, brain death and end-of-life aspects. For each topic, the current medical evidence is followed by a detailed discussion of the ethical issues involved.

Guide to Safety and Quality Assurance for the Transplantation of Organs, Tissues and Cells

Author : Council of Europe Publishing
Publisher : Council of Europe
Page : 184 pages
File Size : 45,9 Mb
Release : 2009-01-01
Category : Medical
ISBN : 9287165688

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Guide to Safety and Quality Assurance for the Transplantation of Organs, Tissues and Cells by Council of Europe Publishing Pdf

Organ transplantation saves thousands of lives each day but raises some questions of principle. This guide, which is published on a biennial basis, provides guidance for all those involved in transplantation and other clinical applications of organs, tissues and cells, with the aim of optimising quality and reducing risks. The topics covered are: quality management, principles for ensuring the quality of organs, tissues and cells; selection of donors; organ procurement and preservation; tissue and cell procurement; tissue establishment; transplantation practices.

Organ Transplants

Author : Carol Ballard
Publisher : Gareth Stevens Publishing LLLP
Page : 68 pages
File Size : 47,7 Mb
Release : 2007-01-12
Category : Juvenile Nonfiction
ISBN : 083687868X

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Organ Transplants by Carol Ballard Pdf

Discusses organ transplants, including the history and development of the surgery, which organs can be transplanted, the steps involved in the surgery, and the problems with transplanting organs.

Textbook of Organ Transplantation Set

Author : Allan D. Kirk,Stuart J. Knechtle,Christian P. Larsen,Joren C. Madsen,Thomas C. Pearson,Steven A. Webber
Publisher : John Wiley & Sons
Page : 0 pages
File Size : 46,5 Mb
Release : 2014-09-15
Category : Medical
ISBN : 9781118870143

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Textbook of Organ Transplantation Set by Allan D. Kirk,Stuart J. Knechtle,Christian P. Larsen,Joren C. Madsen,Thomas C. Pearson,Steven A. Webber Pdf

Brought to you by the world’s leading transplant clinicians, Textbook of Organ Transplantation provides a complete and comprehensive overview of modern transplantation in all its complexity, from basic science to gold-standard surgical techniques to post-operative care, and from likely outcomes to considerations for transplant program administration, bioethics and health policy. Beautifully produced in full color throughout, and with over 600 high-quality illustrations, it successfully: Provides a solid overview of what transplant clinicians/surgeons do, and with topics presented in an order that a clinician will encounter them. Presents a holistic look at transplantation, foregrounding the interrelationships between transplant team members and non-surgical clinicians in the subspecialties relevant to pre- and post-operative patient care, such as gastroenterology, nephrology, and cardiology. Offers a focused look at pediatric transplantation, and identifies the ways in which it significantly differs from transplantation in adults. Includes coverage of essential non-clinical topics such as transplant program management and administration; research design and data collection; transplant policy and bioethical issues. Textbook of Organ Transplantation is the market-leading and definitive transplantation reference work, and essential reading for all transplant surgeons, transplant clinicians, program administrators, basic and clinical investigators and any other members of the transplantation team responsible for the clinical management or scientific study of transplant patients.

A Gift of Life

Author : R.Y. Carne
Publisher : Springer Science & Business Media
Page : 122 pages
File Size : 43,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401158930

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A Gift of Life by R.Y. Carne Pdf

In the past few years the transplantation of organs in man has received publicity unprecedented in medical history. The first heart grafts were covered by press, radio, and television on a scal~ equiva lent to the news of the outbreak of a major war. Unwarranted and extravagant optimism has been followed by bitter criticism. This has undermined public confidence in the medical profession and seriously impeded progress in an important endeavour aimed at reducing human suffering. This unfortunate situation has arisen from widespread ignorance amongst the public and the medical profession of the background, present achievements, and future potential of organ grafting. Short statements by experts, frequently misquoted or cut short by television interviewers, and misinformed derogatory pronouncements by prejudiced medically qualified men, with no knowledge of the field, have produced a sorry state of confusion. It is the purpose of this book to attempt to clarify organ transplantation. The principles of organ transplantation are common to all organs but I will confine most of the discussion to transplantation of four vital organs, namely the kidney, liver, heart, and lung. ROY CALNE Cambridge January 1970 CONTENTS Preface IX List of Illustrations Xlll Acknowledgements XVll I. THE IDEA I II. THE SURGERY 7 III. REJECTION 15 IV. PREVENTION OF REJECTION 23 v. TISSUEMATCHING 39 VI. ORGAN PRESERVATION 47 VII. SUITABLE DONORS 53 VIII. ORGAN TRANSPLANTS 57 IX. ETHICS AND THE LAW 81 X.

Organ and Body Donation

Author : Hal Marcovitz
Publisher : ABDO
Page : 116 pages
File Size : 44,6 Mb
Release : 2010-09-01
Category : Juvenile Nonfiction
ISBN : 1616135247

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Organ and Body Donation by Hal Marcovitz Pdf

This title gives readers a balanced look at the arguments surrounding organ and body donation. Readers will learn the history of organ and body donation, as well as the pros and cons of organ transplants and harvesting organs. Color photos and informative sidebars accompany easy-to-follow text. Features include a table of contents, timeline, facts, additional resources, web sites, a glossary, a bibliography, and an index. Essential Viewpoints is a series in Essential Library, an imprint of ABDO Publishing Company.

Cellular Transplantation

Author : Craig Halberstadt,Dwaine F. Emerich
Publisher : Elsevier
Page : 696 pages
File Size : 54,8 Mb
Release : 2011-10-10
Category : Science
ISBN : 9780080469041

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Cellular Transplantation by Craig Halberstadt,Dwaine F. Emerich Pdf

There have been tremendous strides in cellular transplantation in recent years, leading to accepted practice for the treatment of certain diseases, and use for many others in trial phases. The long history of cellular transplantation, or the transfer of cells from one organism or region of the body to another, has been revolutionized by advances in stem cell research, as well as developments in gene therapy. Cellular Transplants: From Lab to Clinic provides a thorough foundation of the basic science underpinning this exciting field, expert overviews of the state-of-the-art, and detailed description of clinical success stories to date, as well as insights into the road ahead. As highlighted by this timely and authoritative survey, scale-up technologies and whole organ transplantation are among the hurdles representing the next frontier. The contents are organized into four main sections, with the first covering basic biology, including transplant immunology, the use of immunosuppressive drugs, stem cell biology, and the development of donor animals for transplantation. The next part looks at peripheral and reconstructive applications, followed by a section devoted to transplantation for diseases of the central nervous system. The last part presents efforts to address the key challenges ahead, such as identifying novel transplantable cells and integrating biomaterials and nanotechnology with cell matrices. Provides detailed description of clinical trials in cell transplantation Review of current therapeutic approaches Coverage of the broad range of diseases addressed by cell therapeutics Discussion of stem cell biology and its role in transplantation

Flesh and Blood

Author : Susan E. Lederer
Publisher : Oxford University Press
Page : 240 pages
File Size : 54,7 Mb
Release : 2008-04-24
Category : Medical
ISBN : 9780190289775

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Flesh and Blood by Susan E. Lederer Pdf

Organ transplantation is one of the most dramatic interventions in modern medicine. Since the 1950s thousands of people have lived with 'new' hearts, kidneys, lungs, corneas, and other organs and tissues transplanted into their bodies. From the beginning, though, there was simply a problem: surgeons often encountered shortages of people willing and able to give their organs and tissues. To overcome this problem, they often brokered financial arrangements. Yet an ethic of gift exchange coexisted with the 'commodification of the body'. The same duality characterized the field of blood transfusion, which was essential to the development of modern surgery. This book will be the first to bring together the histories of blood transfusion and organ transplantation. It will show how these two fields redrew the lines between self and non-self, the living and the dead, and humans and animals. Drawing on newspapers, magazines, legal cases, films and the papers and correspondence of physicians and surgeons, Lederer will challenge the assumptions of some bioethicists and policymakers that popular fears about organ transplantation necessarily reflect timeless human concerns and preoccupations with the body. She will show how notions of the body- intact, in parts, living and dead- are shaped by the particular culture in which they are embedded.

Marginal Donors

Author : Takehide Asano,Norihide Fukushima,Takashi Kenmochi,Naoto Matsuno
Publisher : Springer Science & Business Media
Page : 270 pages
File Size : 41,8 Mb
Release : 2014-03-17
Category : Medical
ISBN : 9784431544845

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Marginal Donors by Takehide Asano,Norihide Fukushima,Takashi Kenmochi,Naoto Matsuno Pdf

In response to persistent donor organ shortages, organs from marginal donors, such as expanded criteria donors (ECD) and donation after cardiac death (DCD) donors, are now accepted and have been successfully transplanted, reducing the waiting times for transplantation. Especially in Japan, transplantation of DCD kidneys has a relatively long history because of the difficulty or lack of national consensus in accepting brain death, which has made it possible to accumulate considerable clinical experience. Thus, the current organ shortage has stimulated interest in the use of marginal donors for transplantation. On the other hand, however, it is known that these organs have a high rate of delayed graft function and a more complicated postoperative course. These drawbacks have created the greatest clinical challenge in transplantation to date because of the current shortage and limitations of donors using ECD and DCD. This book, prepared by distinguished authorities in their fields, is intended for clinicians and researchers. It highlights the use of marginal donors as a comparatively novel source of transplantation organs and provides a thorough overview of marginal donors from their historical origins to recent clinical applications, including the state-of-the-art science of organ/donor management, procurement, and preservation. Also provided is valuable information on ABO-incompatible donors which extend the availability of donor sources. Each chapter offers an individual analysis of the optimal requirements for the safe management and preservation of organs, including the heart, lung, liver, kidney, pancreas, and pancreatic islets.