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Author : United States. Department of Health, Education, and Welfare. Ethics Advisory Board
Publisher : Unknown
Page : 142 pages
File Size : 46,7 Mb
Release : 1979
Category : Fertilization in vitro, Human
ISBN : UOM:39015000854060
Author : Don P. Wolf,Martin M. Quigley
Publisher : Springer Science & Business Media
Page : 441 pages
File Size : 50,8 Mb
Release : 2013-06-29
Category : Psychology
ISBN : 9781468447125
The births of more than 100 apparently normal infants at term following pregnancies initiated by in vitro fertilization and embryo transfer testifies to the successful clinical application of insights obtained from studies in reproductive biology over the last 20 years. In women, these studies have included: 1) characterization of the changes in blood hormone profiles throughout ovulatory menstrual cycles; 2) documentation of the hormonal composition of antral fluid in developing and degenerating preovulatory follicles; 3) correlation of these observations with the state of oocyte maturation and the fertilizability of the oocyte; 4) application of pharmacologic agents for perturbing the normal hormone profiles to regulate the number of preovulatory follicles developing and the time of ovulation; and 5) development of non-invasi ve methods for monitoring follicular development. Optimizing methods for maturing and fertilizing eggs, for moni toring normal development in vi tro, and for transferring and achieving implantation of embryos are continuing concerns of physicians and scientists responsible for extant programs. In addition, all serious students of reproductive biology should critically examine every facet of the processes which must concatenate to assure birth of normal infants following pregnancies achieved by these methods. However, the literature which contains the informational substrate is dispersed widely in a plethora of journals not always readily accessible. Bringing the essentials together facilitates both rapid retrieval of data and access to relevant literature.
Author : United States. Department of Health, Education, and Welfare. Ethics Advisory Board
Publisher : Unknown
Page : 870 pages
File Size : 55,7 Mb
Release : 1979
Category : Embryology, Human
ISBN : IND:30000105866507
Author : Don P. Wolf,Martin M. Quigley
Publisher : Springer
Page : 440 pages
File Size : 46,5 Mb
Release : 2012-10-20
Category : Psychology
ISBN : 1468447130
The births of more than 100 apparently normal infants at term following pregnancies initiated by in vitro fertilization and embryo transfer testifies to the successful clinical application of insights obtained from studies in reproductive biology over the last 20 years. In women, these studies have included: 1) characterization of the changes in blood hormone profiles throughout ovulatory menstrual cycles; 2) documentation of the hormonal composition of antral fluid in developing and degenerating preovulatory follicles; 3) correlation of these observations with the state of oocyte maturation and the fertilizability of the oocyte; 4) application of pharmacologic agents for perturbing the normal hormone profiles to regulate the number of preovulatory follicles developing and the time of ovulation; and 5) development of non-invasi ve methods for monitoring follicular development. Optimizing methods for maturing and fertilizing eggs, for moni toring normal development in vi tro, and for transferring and achieving implantation of embryos are continuing concerns of physicians and scientists responsible for extant programs. In addition, all serious students of reproductive biology should critically examine every facet of the processes which must concatenate to assure birth of normal infants following pregnancies achieved by these methods. However, the literature which contains the informational substrate is dispersed widely in a plethora of journals not always readily accessible. Bringing the essentials together facilitates both rapid retrieval of data and access to relevant literature.
Author : Don P. Wolf
Publisher : Springer Science & Business Media
Page : 427 pages
File Size : 54,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461310051
The use of human in vitro fertilization in the management of infertility is the outgrowth of years of laboratory observations on in vitro sperm-egg interaction. "The editors of this work have themselves contributed significantly to basic knowledge of the mammalian fertilization process. The observations of Don Wolf on sperm penetration, the block to polyspermy and, most recently, sperm hyperactivation in the monkey and human, Gregory Kopf's elucidation of the mechanisms of sperm activation during penetration and the reciprocal dialogue between sperm and egg, and Barry Bavister's definition of culture conditions and requirements necessary for in vitro oocyte maturation, fertilization and development in model mammalian systems including nonhuman primates have contributed greatly to our understanding of the mammalian fertilization process. Wolf, Kopf and Gerrity have enjoyed substantial interaction with clinicians in Departments of Obstetrics and Gynecology and have been directly involved with successful IVF programs. Both Wolf and Kopf have served as research scientists in the Division of Reproductive Biology at the University of Pennsylvania, which, for more than 22 years, has fostered co-mingling of clinically oriented and basic science faculty. It is through such interaction, which clearly exists at many institutions including the University of Wisconsin, that the process of technology transfer is best served. Without an exquisitely coordinated laboratory, there can be no consistent success in human in vitro fertilization. Quality control is pivotal, but close collaboration between the laboratory and the clinic is also essential as information is shared and correlated.
Author : David K. Gardner,Carlos Simón
Publisher : CRC Press
Page : 495 pages
File Size : 53,5 Mb
Release : 2017-06-26
Category : Medical
ISBN : 9781498729475
The new edition of this text admirably fills the need for a primer on the central topics involved in Human In Vitro Fertilization (IVF). Supplying a comprehensive and hands-on approach to IVF, this source presents established state-of-the-art procedures and techniques, as well as the most current research in the field. Expert contributors also discuss the history of IVF and the potential of future research. Offering essential information for reproductive endocrinologists, IVF practitioners and embryologists, this book guides readers though every step of human assisted conception, from patient pre-treatment to monitoring of outcomes.
Author : Alan Trounson,Carl Wood
Publisher : Unknown
Page : 272 pages
File Size : 50,5 Mb
Release : 1984
Category : Medical
ISBN : UOM:39015009551766
Author : Wilfried Feichtinger,Peter Kemeter
Publisher : Springer Science & Business Media
Page : 299 pages
File Size : 50,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642714122
While the organization of an international congress on in vitro fertilization (IVF) was an entirely new venture for us in 1983, since we had no experience but were full of optimism, we approached the organization of a second Congress in Vien na in 1986 much more calmly. Our experience had increased as had the readiness of many of our friends to help and of people interested in cooperating. However, would our Congress not lose its originality on account of the increased routine? This was certainly a possible danger which we wanted to prevent by means of two counter measures. The first concerned the scientific program: the new and trend-setting aspects of IVF would be discussed primarily rather than the results of traditional methods. The second measure concerned the social program, aimed more at private contacts in the intimate and familiar atmosphere of homes and workplace rather than meetings in luxurious but impersonal public institu tions. We believe that both these measures achieved the desired effect. Although we could not avoid some events taking place at the same time, the most important problems were treated and discussed jointly. Thus, the Congress was easy to survey, and all topics were thoroughly discussed.
Author : Don P. Wolf,Richard L. Stouffer,Robert M. Brenner
Publisher : Springer Science & Business Media
Page : 403 pages
File Size : 50,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461227168
It is a genuine honor and a privilege of distinction to provide the foreword for the proceedings that follow. This marvelous symposium reflects the unique qualities of its two principal sponsors. Whenever the Oregon Regional Primate Research Center is involved in matters of science, we see a consistent record of exceptional quality in both the work is unequaled and the people who do it. Likewise, Serono Symposia, USA in assuring a world-class speakers' forum, utterly without taint of commercial influence. The proceedings published herein are a remarkable testimony, not only to the contributors, but to Drs. Brenner, Wolf, Stouffer, and Burnett, who have shepherded its conception, presentation, and publication. Readers will notice immediately one of the universal strengths of this total composition; that is, the diversity of investigational interests among attendees. Presentations on the core topic of primate in vitro fertilization and embryo transfer were joined by specialist presentations in related areas, including human-assisted reproductive technologies, reproductive physiology of the great apes, sperm biology, implantation mechanisms, cryobiology, coculture systems for embryogenesis, micromanipulation technologies, and genetic diagnosis of heritable diseases in the pre embryo. Even though pro-fertility issues understandably dominated this forum, there was significant attention given to fertility-control research, especially the role of primates in this endeavor (more on this subject below).
Author : United States. Department of Health, Education, and Welfare. Ethics Advisory Board
Publisher : Unknown
Page : 128 pages
File Size : 54,6 Mb
Release : 1979
Category : Fertilization in vitro, Human
ISBN : LCCN:79603344
Author : William H. Marshner
Publisher : Unknown
Page : 56 pages
File Size : 49,8 Mb
Release : 1979
Category : Embryology, Human
ISBN : CHI:51562020
Author : David K. Gardner,Michelle Lane
Publisher : Springer Science & Business Media
Page : 254 pages
File Size : 55,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461301493
The field of human artificial reproductive technology (ART) is continually advancing and has witnessed significant changes since the inception of Louise Brown in 1978. Though Louise Brown herself was conceived after the trans fer of a blastocyst, there remain significant confusion and debate regarding the stage at which the human embryo conceived in the laboratory should be replaced in the mother. Developments in culture media formulations, leading to the introduction of sequential media, have brought the role of the blasto cyst in human ART back into the spotlight. It was due to this resurgence of interest in the niche of extended culture in human infertility treatment that the symposium on "ART and the Human Blastocyst" was held. of this meeting within this volume bring to the forefront The proceedings the main issues raised with the transfer of embryos at the blastocyst stage. It is evident from the chapters that follow that ART needs to be perceived as a continuum of procedures, each one dependent on the preceding one, and all equally as important as each other. That is to say, the development of a com petent embryo is ultimately dependent on the quality of the gametes from which it was derived. With regard to the oocyte, this then places the emphasis on the physician to use a stimulation protocol that both produces quality oocytes and does not impair endometrial function. Maintenance of gamete and embryo quality is the laboratory's role.
Author : C. Wood,A. Trounson
Publisher : Springer Science & Business Media
Page : 215 pages
File Size : 53,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781447133179
Man is entering a new era as a result of advances in human reproduction. Techniques have been developed to assist in the creation of man-artificial insemination and, now, in vitro fertilization (IVF). Soon, other new methods, based upon current advances of the IVF procedure, will develop to improve the quality of human reproduction. The book describes the conceptual framework and details of technique concerned with in vitro fertilization and embryo transfer (ET). Edwards and Steptoe first described the technique of IVF and ET and the subsequent births of two normal babies. Since then, the success rate of the system has been improved by the use of fertility drugs to provide more oocytes and preincubation to mature the oocyte before fertilization. As a result of the continued research from Melbourne and Cambridge, more than 100 babies have been born. A free interchange of information between the Cambridge and Melbourne groups has led to a predictable success rate of 15%-20% per laparoscopy, and infertility centres all over the world are now copying the techniques. It is an appropriate time to inform doctors and scientists to help them understand the various procedures involved in IVF and ET. While many advances will occur in the future, the establishment of high success rates in several of the critical steps in the procedure-oocyte pick-up rate (90%), fertilization (>90%) and early embryo development (70%-90% )-signifies that some of the new techniques are stabilized sufficiently to warrant transmission of information by text, rather than scientific journal.
Author : Bin Wu
Publisher : BoD – Books on Demand
Page : 264 pages
File Size : 45,7 Mb
Release : 2012-03-14
Category : Medical
ISBN : 9789535103189
Embryo transfer has become one of the prominent high businesses worldwide. This book updates and reviews some new developed theories and technologies in the human embryo transfer and mainly focus on discussing some encountered problems during embryo transfer, which gives some examples how to improve pregnancy rate by innovated techniques so that readers, especially embryologists and physicians for human IVF programs, may acquire some new and usable information as well as some key practice techniques. Major contents include the optimal stimulation scheme for ovaries, advance in insemination technology, improved embryo transfer technology and endometrial receptivity and embryo implantation mechanism. Thus, this book will greatly add new information for readers to improve human embryo transfer pregnancy rate.
Author : Zsolt Peter Nagy,Alex C. Varghese,Ashok Agarwal
Publisher : Springer
Page : 962 pages
File Size : 41,6 Mb
Release : 2019-07-03
Category : Health & Fitness
ISBN : 9783319430119
Now in its revised and expanded second edition - including over 20 new chapters - this comprehensive textbook remains a unique and accessible description of the current and developing diagnostic and treatment techniques and technologies comprising in vitro fertilization (IVF). Arranged thematically in sections, each chapter covers a key topic in IVF in a sensible presentation. Parts one and two describe the planning, design and organization of an ART unit and IVF laboratory and equipment and systems, respectively. The sections that follow provide detailed descriptions of IVF techniques, embryo culture methods, sperm processing and selection, insemination procedures, micromanipulation, embryo evaluation, cryopreservation, and embryo transfer. Concluding sections address issues of management and regulation of ART labs across the globe, as well as special topics and emerging techniques and devices. Chapter authors, all experts in the field, contribute their expertise from around the world. With the addition of learning key points and review questions at the beginning and end of each chapter, this new edition of In Vitro Fertilization is a readily accessible, high quality instructional resource for reproductive medicine trainees at all levels. Practicing reproductive endocrinologists, urologists, and embryologists also will find value in the book, as will infertility researchers.