Icrf Handbook Of Genome Analysis

Author : N. S. Spurr,S. Bryant,Bryan Young
Publisher : John Wiley & Sons
Page : 1038 pages
File Size : 41,8 Mb
Release : 2009-06-03
Category : Science
ISBN : 9781444313475

Get Book

ICRF Handbook of Genome Analysis by N. S. Spurr,S. Bryant,Bryan Young Pdf

The combined power of genetic analysis and recombinant DNA technology to analyse entire genomes has moved biomedical research into a new and revolutionary phase. The complete sequencing and mapping of the human genome, as well as the genomes of other model organisms, will be the basis for our future understanding of human disease, and will allow us to answer fundamental questions about development and evolution. T The new ICRF Handbook of Genome Analysis is the essential guide to the enormous range of techniques available to the researcher for both the genetic and physical mapping of the genome, as well as the sequencing and analysis of DNA. It is both a protocol manual and a comprehensive information resource. Written by international experts, each chapter presents a state-of-the-art review of a methodology. Methods are fully described and evaluated; their advantages and disadvantages discussed; and their suitability for different investigations considered. Step-by-step protocols, including computer analyses, are given for 123 essential experimental procedures. 'Troubleshooting' sections discuss possible reasons for failure and offer remedies. The primary focus is on human genetics and the benefits of an understanding of the genome for the diagnosis and treatment of human disease. The book also considers the current state of progress in the analysis of genomes of many model organisms, including plants. A major part of the work provides detail on Internet resources as well as basic data on human and other genomes, including mapped disease genes and mouse knockouts. Covers not only the human genome in relation to cancers and other human diseases, but also the genomes of all important model organisms Contains 123 easy-to-follow protocols for essential experimental procedures Reviews a vast range of other information resources, including journals and the Internet * provides an invaluable listing of suppliers of laboratory materials Has been written by international experts from their own practical experience Is mandated by the Imperial Cancer Research Fund - a leader in research in this field Has a sturdy spiral binding within a hardback case for ease of use in the lab

Author : Eric D. Green
Publisher : CSHL Press
Page : 532 pages
File Size : 42,6 Mb
Release : 1997
Category : DNA
ISBN : 0879695153

Get Book

Genome Analysis by Eric D. Green Pdf

A complement to the bible of recombinant DNA, Molecular Cloning, these manuals are essential for every laboratory in which genes are being studied.

Author : Anonim
Publisher : Unknown
Page : 688 pages
File Size : 40,7 Mb
Release : 1997
Category : Gene mapping
ISBN : STANFORD:36105023633170

Get Book

Genome Analysis by Anonim Pdf

A complement to the bible of recombinant DNA, Molecular Cloning, these manuals are essential for every laboratory in which genes are being studied.

Author : Bruce Birren
Publisher : Unknown
Page : 648 pages
File Size : 43,7 Mb
Release : 2006
Category : Electronic
ISBN : OCLC:770845047

Get Book

Genome Analysis by Bruce Birren Pdf

Author : Manuel Hallen,Andreas Klepsch
Publisher : IOS Press
Page : 306 pages
File Size : 51,9 Mb
Release : 1995
Category : Medical
ISBN : 9051991754

Get Book

Human Genome Analysis Programme by Manuel Hallen,Andreas Klepsch Pdf

The first Human Genome Analysis Programme (HGAP) was launched for the years 1990-1992. The aim of this programme has been to ensure a significant European contribution to the worldwide effort to map the human genome and, in the long term, to set a basis for support of European research activities in future wide-ranging medical applications.

Author : Bruce Birren
Publisher : Unknown
Page : 675 pages
File Size : 46,9 Mb
Release : 2006
Category : Electronic
ISBN : OCLC:770852379

Get Book

Genome Analysis by Bruce Birren Pdf

Author : Bruce Birren,Eric D. Green,Sue Klapholz,Richard M. Myers,Jane Roskams
Publisher : Unknown
Page : 536 pages
File Size : 50,5 Mb
Release : 1997
Category : Medical
ISBN : 0879694963

Get Book

Analyzing DNA by Bruce Birren,Eric D. Green,Sue Klapholz,Richard M. Myers,Jane Roskams Pdf

MIT Center for Genome Research, Cambridge, MA. First in a four-volume set. Lab manual describing the theoretical background, lab protocols, and resource materials for applying genome analysis techniques to the study of genes and genomes. Plastic-comb spiral binding.

Author : Bruce Birren
Publisher : Unknown
Page : 463 pages
File Size : 53,7 Mb
Release : 2006
Category : Electronic
ISBN : OCLC:770845044

Get Book

Genome Analysis by Bruce Birren Pdf

Author : Michael Donnenberg
Publisher : Elsevier
Page : 453 pages
File Size : 54,5 Mb
Release : 2002-10-09
Category : Science
ISBN : 9780080494814

Get Book

E. coli by Michael Donnenberg Pdf

Although most strains of E. coli bacteria are harmless and live in the intestines of healthy humans and animals, several strains can produce powerful toxins and cause severe illness in humans. This versatile pathogen is best known for being transmitted to humans through contaminated foods — such as undercooked meat and unpasteurized fruit juice — and has attracts much attention when serious outbreaks occur. E. coli is capable of causing a wide variety of diseases — from urinary tract infections to meningitis. A considerable amount of media coverage has recently been devoted to one particular strain of E. coli, responsible for an estimated 73,000 cases of infection and 61 deaths in the United States each year. Knowing more about the biology, the evolution, and the genetic basis of this pathogen is crucial to future prevention of infection and illness. Pathogenic E. coli is a unique, comprehensive analysis of the biology and molecular mechanisms that enable this ubiquitous organism to thrive. Leading investigators in the field discuss the molecular basis of E. coli pathogenesis followed by chapters on genomics and evolution. Detailed descriptions of distinct strains reveal the molecular pathogenesis of each and the causes of intestinal and extra-intestinal infections in humans. Pathogenic E. coli concludes with a presentation of virulance factors, common to two or more pathotypes. This unique collection presents timely and vital information on understanding the inner workings of E. coli, which will lend key insights into disease prevention research. Single source of information of E. coli pathogenesis Expert authors Comprehensive coverage Molecular mechanisms Biology, evolution and genomics Recent advances

Author : Bruce Birren
Publisher : Unknown
Page : 648 pages
File Size : 47,8 Mb
Release : 2006
Category : Electronic
ISBN : OCLC:770845046

Get Book

Genome Analysis by Bruce Birren Pdf

Author : Diane Schmidt,Elisabeth B. Davis
Publisher : CRC Press
Page : 484 pages
File Size : 51,9 Mb
Release : 2001-12-06
Category : Language Arts & Disciplines
ISBN : 9780824741716

Get Book

Using The Biological Literature by Diane Schmidt,Elisabeth B. Davis Pdf

"Provides an in-depth review of current print and electronic tools for research in numerous disciplines of biology, including dictionaries and encyclopedias, method guides, handbooks, on-line directories, and periodicals. Directs readers to an associated Web page that maintains the URLs and annotations of all major Inernet resources discussed in th

Author : David Moore,LilyAnn Novak Frazer
Publisher : Springer Science & Business Media
Page : 358 pages
File Size : 51,7 Mb
Release : 2007-06-14
Category : Science
ISBN : 9780387224572

Get Book

Essential Fungal Genetics by David Moore,LilyAnn Novak Frazer Pdf

Most genetics textbooks deal adequately with plant and animal genetics, but tend to neglect fungi. The authors have produced a book that will compensate for this imbalance. This book discusses the genetics of fungi in a way that is attractive and challenging, succinct yet comprehensive, sensitive to commercial and applied aspects, yet also theoretical, dealing with their genetics from molecules to individuals to population. This short text will be an ideal supplement to the established basic genetics texts or can be used as the sole text for an advanced course devoted to fungal genetics.

Author : Stephen A. Krawetz,David D. Womble
Publisher : Springer Science & Business Media
Page : 720 pages
File Size : 47,9 Mb
Release : 2003-01-31
Category : Science
ISBN : 9781592593354

Get Book

Introduction to Bioinformatics by Stephen A. Krawetz,David D. Womble Pdf

to Bioinformatics A Theoretical and Practical Approach Edited by Stephen A. Krawetz, PhD Wayne State University School of Medicine, Detroit MI and David D. Womble, PhD Wayne State University School of Medicine, Detroit, MI ~ Springer Science+ ~ Business Media, LLC © 2003 Springer Science+Business Media New York Originally published by Humana Press !ne. in 2003 Softcover reprint of the hardcover 1 st edition 2003 humanapress.com Ali rights reserved. No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise without written permission from the Publisher. Ali papers, comments, opinions, conclusions, or recommendations are those of the author(s), and do not necessarily reflect the views of the publisher. This publication is printed on acid-free paper. G) ANSI Z39.48-1984 (American Standards Institute) Permanence of Paper for Printed Library Materials. Production Editor: Mark J. Breaugh. Cover design by Patricia F. Cleary and Paul A. Thiessen. Cover illustration by Paul A. Thiessen, chemicalgraphics.com.

Author : S Jeffery,Prof Steven Myint,J Booth
Publisher : Taylor & Francis
Page : 118 pages
File Size : 51,9 Mb
Release : 2023-05-31
Category : Science
ISBN : 9781000951073

Get Book

Molecular Diagnosis by S Jeffery,Prof Steven Myint,J Booth Pdf

There has been a rapid introduction of nucleic acid-based analysis techniques into diagnostic laboratories and routine screening procedures. This timely book presents a concise overview of the molecular diagnosis of human disease. It focuses on the techn

Author : Wendy Bickmore
Publisher : OUP Oxford
Page : 234 pages
File Size : 40,9 Mb
Release : 1999-05-20
Category : Science
ISBN : 9780191565809

Get Book

Chromosome Structural Analysis by Wendy Bickmore Pdf

The DNA of eukaryotes is packaged into chromosomes - each chromosome consisting of a very long molecule of DNA and various proteins (e.g. histones), and the number of chromosomes being characteristic for the species concerned. Chromosome analysis can provide a great deal of information for many aspects of cellular genetics such as DNA replication, protein:DNA interactions and genetic manipulation. The book is structured in a methodical fashion - the introductory chapters are centred around analysis of chromatin with chapters on the mapping of protein:DNA interactions in vivo using ligation-mediated PCR and the mapping of chromatin-associated proteins by formaldehyde cross-linking. The next chapters concentrate on the study of whole chromosome structure, including: fission yeast chromosome analysis using FISH and CHIP, isolation of vertebrate metaphase chromosomes and their analysis by FISH, the study of vertebrate chromosome progression through mitosis, and the analysis of mammalian interphase chromosomes by immunofluorescence and FISH. There then follow chapters on FISH in whole-mount tissues and the analysis of the sub-structure of mammalian nuclei in vitro. The final two chapters deal with the experimental manipulation of chromosome structure, including: chromosome assembly in vitro using Xenopus egg extracts and chromosome fragmentation in vertebrate cell lines. This comprehensive and informative laboratory manual includes a diverse range of experimental models for the analysis of chromosomes - such as vertebrates, Drosophila, yeast and Xenopus. Fully illustrated, it focuses on modern techniques and approaches to the study of chromosome structure and will be invaluable to researchers and academic staff in genetics, biomedical science and molecular biology.