Immunoregulation In Health And Disease

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Immunoregulation in Health and Disease

Miodrag L. Lukic,Miodrag Colic,Marija Mostarica-Stojkovic,Kosta Cuperlovic
Immunoregulation in Health and Disease Book PDF

Author : Miodrag L. Lukic,Miodrag Colic,Marija Mostarica-Stojkovic,Kosta Cuperlovic
Publisher : Academic Press
Page : 468 pages
File Size : 47,8 Mb
Release : 1997-05-14
Category : Medical
ISBN : 0080534570

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Immunoregulation in Health and Disease by Miodrag L. Lukic,Miodrag Colic,Marija Mostarica-Stojkovic,Kosta Cuperlovic Pdf

Immunoregulation in Health and Disease, edited by Lukic, Colic, Mostarica-Stojkovic and Cuperlovic is a multi-authored volume covering the field of Immunoregulation, and will be essential reading for all researchers working in Immunology. Each section includes at least 10 papers contributed by experts from around the World, and covers in detail the wealth of knowledge relating to immunoregulation, both in health and disease. This book will provide an invaluable overview of immune system behaviour. The book is divided into four sections: Regulatory, effectory, and accessory cells of the immune response Molecular and cellular immunoregulatory mechanisms Hypersensitivity and autoimmunity Host reactivity to graft, tumour and infection

T–cell Activation in Health and Disease

M Feldmann,R Maini,J. N. Woody
T cell Activation in Health and Disease Book PDF

Author : M Feldmann,R Maini,J. N. Woody
Publisher : Academic Press
Page : 271 pages
File Size : 53,6 Mb
Release : 2017-05-04
Category : Health & Fitness
ISBN : 9781483275581

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T–cell Activation in Health and Disease by M Feldmann,R Maini,J. N. Woody Pdf

T-cell Activation in Health and Disease is a collection of papers presented at the "T-cell Activation in Health and Disease—Disorders of Immune Regulation—Infection and Autoimmunity" workshop held in Oxford on September 25-29, 1988. This book discusses the progress occurring in T-cell immunity research. One paper discusses the effects of two interaction clones of T-cells that can define the T-cell immunoregulatory network. Another paper discusses the relationship between connectivity and tolerance of the immune network. This paper then suggests the possibility that autoimmunity arises because self-reactive clones are inadequately connected to the network. Another paper reviews the cell-mediated responses in the synovial fluids, as well as the interaction of rheumatoid arthritis synovial fluid dendritic cells and T lymphocytes. The book also examines why attempts for protective immunity to the HIV virus have not been successful. One article then discusses the goals of immunologic intervention in autoimmune disease by using an approach involving the cellular and cytokine targets and their deployment. This text can prove significant for scientists in the field of pharmacology, cellular biology, and researchers in the field of immunology and infectious diseases.

Immunoregulation

Nicola Fabris
Immunoregulation Book PDF

Author : Nicola Fabris
Publisher : Springer Science & Business Media
Page : 473 pages
File Size : 40,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781468445473

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Immunoregulation by Nicola Fabris Pdf

Immunoregulation is one of the areas which has witnessed the most explosive advances of immunology during the past decade. It is in this area that the current view of the immune system has arisen and developed. There is indeed little doubt that immune reactions are primarily determined by messages which are genera ted within the immune system and passed among different types of immunologie cells. This cell communication not only determines the type, intensity and duration of the response after perturbation of the immune system by exogenous antigens, but it is also essential for preventing autoimmune reactions and their clinical conse quences. In order to assure aperfect balance within the enormous com plexity of the immune system, it is not surprising that multiple self-regulatory mechanisms are organized at different levels, such as antibody feedback, idiotypic-anti-idiotypic responses, suppres sor and helper T cells, lymphokine signals and genetic require ments. A nu mb er of observations in recent years have, however, demonstrated that consistent contributions to the immunological homeostasis are given also by signals generated outside of the immune system, namely,in the central and autonomous nervous system as weIl as in the endocrine apparatus. Furthermore, the interactions between the immune system and the other body homestatic mechanisms seem to be bidirectional: if immunological cells may be targets of neuroendocrinological factors, immunological products seem in turn to contribute to the neuro endocrine homeostasis.

Co-signal Molecules in T Cell Activation

Miyuki Azuma,Hideo Yagita
Co signal Molecules in T Cell Activation Book PDF

Author : Miyuki Azuma,Hideo Yagita
Publisher : Springer Nature
Page : 326 pages
File Size : 55,7 Mb
Release : 2019-11-22
Category : Medical
ISBN : 9789813297173

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Co-signal Molecules in T Cell Activation by Miyuki Azuma,Hideo Yagita Pdf

This book equips young immunologists and health professionals with a clear understanding of the fundamental concepts and roles of co-signal molecules and in addition presents the latest information on co-stimulation. The first part of the book is devoted to co-signal molecules and the regulation of T cells. Following an initial overview, subsequent chapters examine each co-signal molecule in turn and discuss the mechanisms by which co-signal molecules regulate the different types of T cell. The second part covers various clinical applications, including in autoimmune disease, neurological disorders, transplantation, graft-versus-host disease, and cancer immunotherapy. To date, co-stimulation blockade and co-inhibition blockade have shown beneficial effects and many additional clinical trials targeting co-signal molecules are ongoing. The mechanisms underlying these successful treatments are explained and the future therapeutic potential in the aforementioned diseases is evaluated. Co-signal Molecules in T Cell Activation will be a valuable reference guide to co-stimulation for basic and clinical researchers in the fields of both immunology and pharmaceutical science.

Co-signal Molecules in T Cell Activation

Miyuki Azuma,Hideo Yagita
Co signal Molecules in T Cell Activation Book PDF

Author : Miyuki Azuma,Hideo Yagita
Publisher : Springer
Page : 0 pages
File Size : 54,8 Mb
Release : 2020-12-31
Category : Medical
ISBN : 9813297190

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Co-signal Molecules in T Cell Activation by Miyuki Azuma,Hideo Yagita Pdf

This book equips young immunologists and health professionals with a clear understanding of the fundamental concepts and roles of co-signal molecules and in addition presents the latest information on co-stimulation. The first part of the book is devoted to co-signal molecules and the regulation of T cells. Following an initial overview, subsequent chapters examine each co-signal molecule in turn and discuss the mechanisms by which co-signal molecules regulate the different types of T cell. The second part covers various clinical applications, including in autoimmune disease, neurological disorders, transplantation, graft-versus-host disease, and cancer immunotherapy. To date, co-stimulation blockade and co-inhibition blockade have shown beneficial effects and many additional clinical trials targeting co-signal molecules are ongoing. The mechanisms underlying these successful treatments are explained and the future therapeutic potential in the aforementioned diseases is evaluated. Co-signal Molecules in T Cell Activation will be a valuable reference guide to co-stimulation for basic and clinical researchers in the fields of both immunology and pharmaceutical science.

T-cell Activation in Health and Disease

Marc Feldmann,R. N. Maini
T cell Activation in Health and Disease Book PDF

Author : Marc Feldmann,R. N. Maini
Publisher : Unknown
Page : 264 pages
File Size : 51,6 Mb
Release : 1989-01
Category : Autoimmunity
ISBN : 0122526821

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T-cell Activation in Health and Disease by Marc Feldmann,R. N. Maini Pdf

T-cell Activation in Health and Disease is a collection of papers presented at the ""T-cell Activation in Health and Disease-Disorders of Immune Regulation-Infection and Autoimmunity"" workshop held in Oxford on September 25-29, 1988. This book discusses the progress occurring in T-cell immunity research. One paper discusses the effects of two interaction clones of T-cells that can define the T-cell immunoregulatory network. Another paper discusses the relationship between connectivity and tolerance of the immune network. This paper then suggests the possibility that autoimmunity arises becaus...

Immunoregulatory Aspects of Immunotherapy

Seyyed Shamsadin Athari
Immunoregulatory Aspects of Immunotherapy Book PDF

Author : Seyyed Shamsadin Athari
Publisher : Unknown
Page : 240 pages
File Size : 42,7 Mb
Release : 2018
Category : Microbiology
ISBN : 178923509X

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Immunoregulatory Aspects of Immunotherapy by Seyyed Shamsadin Athari Pdf

Immunotherapy is an innovative, leading and valuable approach to the treatment and control of many diseases. It can solve many problems of public health worldwide. Many people in numerous countries are suffering from a wide range of diseases (communicable and non-communicable) that can be cured or controlled by the immune system and immunotherapy. Some immunological diseases (i.e. allergic reactions and asthma, autoimmune disease, immunodeficiency disease, hypersensitivity reactions, etc.) have immune response pathophysiology and by controlling immune system mechanisms, these diseases can be controlled and cured. Immunoregulatory Aspects of Immunotherapy focuses on immune system mechanism, diagnosis, treatment and other related problems. The chapters have applicable and scientific data in immunotherapeutic approaches based on medical sciences, and would be of benefit to all researchers in immunology, allergy and asthma fields. The book discusses the prevention, diagnosis, treatment and follow-up of patients who have dangerous diseases. We hope this book will be a new approach to the immunotherapy of diseases and will improve public health and wellbeing.

Stress Challenges and Immunity in Space

Alexander Choukèr
Stress Challenges and Immunity in Space Book PDF

Author : Alexander Choukèr
Publisher : Springer Nature
Page : 756 pages
File Size : 42,6 Mb
Release : 2019-11-27
Category : Medical
ISBN : 9783030169961

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Stress Challenges and Immunity in Space by Alexander Choukèr Pdf

This book explains how stress – either psychological or physical – can activate and/or paralyse human innate or adaptive immunity. Adequate immunity is crucial for maintaining health, both on Earth and in space. During space flight, human physiology is specifically challenged by complex environmental stressors, which are most pronounced during lunar or interplanetary missions. Adopting an interdisciplinary approach, the book identifies the impact of these stressors – the space exposome – on immunity as a result of (dys-)functions of specific cells, organs and organ networks. These conditions (e.g. gravitation changes, radiation, isolation/confinement) affect immunity, but at the same time provide insights that may help to prevent, diagnose and address immune-related health alterations. Written by experts from academia, space agencies and industry, the book is a valuable resource for professionals, researchers and students in the field of medicine, biology and technology. The chapters “The Impact of Everyday Stressors on the Immune System and Health”, “Stress and Radiation Responsiveness” and “Assessment of Radiosensitivity and Biomonitoring of Exposure to Space adiation” are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Mechanisms of Immune Regulation

Richard D. Granstein
Mechanisms of Immune Regulation Book PDF

Author : Richard D. Granstein
Publisher : S. Karger AG (Switzerland)
Page : 360 pages
File Size : 54,9 Mb
Release : 1994
Category : Medical
ISBN : PURD:32754064505856

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Mechanisms of Immune Regulation by Richard D. Granstein Pdf

Among the topics reviewed are T and B cell tolerance, clonal deletion, suppressor cells, mechanisms of immune privileged sites and experimental models of tumor immunity. Oral tolerance, ultraviolet radiation and photosensitized effects on immunity, allograft management, T cell vaccination and regulation of immunity with T cell epitopes are discussed from the point of view of possible therapeutic application.

Essential Aspects of Immunometabolism in Health and Disease

Niels Olsen Saraiva Camara,Jose C Alves-Filho,Pedro Manoel Mendes de Moraes-Vieira,Vinicius Andrade-Oliveira
Essential Aspects of Immunometabolism in Health and Disease Book PDF

Author : Niels Olsen Saraiva Camara,Jose C Alves-Filho,Pedro Manoel Mendes de Moraes-Vieira,Vinicius Andrade-Oliveira
Publisher : Springer Nature
Page : 285 pages
File Size : 41,9 Mb
Release : 2021-10-21
Category : Medical
ISBN : 9783030866846

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Essential Aspects of Immunometabolism in Health and Disease by Niels Olsen Saraiva Camara,Jose C Alves-Filho,Pedro Manoel Mendes de Moraes-Vieira,Vinicius Andrade-Oliveira Pdf

Immunometabolism has emerged as an intersectional crossroad between metabolism and immune response. Over the past decade, it has become clear that most - if not all - immune cell functions are not separated from cellular metabolism. Although seminal works have addressed the metabolic fate of immune cells during differentiation and function, the physiological status of a given tissue is also dependent on the cell metabolism. The dialogue between immune cells and their microenvironment can also modulate cellular metabolism, which can trigger the onset and progression of a multitude of inflammation-mediated diseases. Thus, uncovering the specific characteristics of the metabolism in different immune cells types and in different conditions, can shed light into the molecular mechanisms of disease and help develop new drugs and therapeutic strategies to treat immune diseases. The edited volume Essentials aspects of Immunometabolism will give the readers a broad view on how metabolic pathways can influence many types of immune cells during activation, differentiation and function, in health and disease. Of note, the structure of the book was created thinking not only on the experienced immunologist but also on undergraduate and graduate students, physicians, and all members of the scientific community interested in this exciting field of research.

Treating Infectious Diseases in a Microbial World

National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on New Directions in the Study of Antimicrobial Therapeutics: Immunomodulation,Committee on New Directions in the Study of Antimicrobial Therapeutics: New Classes of Antimicrobials
Treating Infectious Diseases in a Microbial World Book PDF

Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on New Directions in the Study of Antimicrobial Therapeutics: Immunomodulation,Committee on New Directions in the Study of Antimicrobial Therapeutics: New Classes of Antimicrobials
Publisher : National Academies Press
Page : 102 pages
File Size : 45,7 Mb
Release : 2006-01-03
Category : Medical
ISBN : 9780309180689

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Treating Infectious Diseases in a Microbial World by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on New Directions in the Study of Antimicrobial Therapeutics: Immunomodulation,Committee on New Directions in the Study of Antimicrobial Therapeutics: New Classes of Antimicrobials Pdf

Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.

Immune Regulation

Marc Feldmann,N. A. Mitchison
Immune Regulation Book PDF

Author : Marc Feldmann,N. A. Mitchison
Publisher : Springer Science & Business Media
Page : 384 pages
File Size : 55,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461249962

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Immune Regulation by Marc Feldmann,N. A. Mitchison Pdf

Leukocyte culture conferences have a long pedigree. This volume records some of the scientific highlights of the 16th such annual con ference, and is a witness to the continuing evolution and popularity of leukocyte culture and of immunology. There is strong evidence of the widening horizons of immunology, both technically, with the obviously major impact of molecular biology into our understanding of cellular processes, and also conceptually. Traditionally, the 'proceedings' of these conferences have been published. But have the books produced really recorded the major part of the conference, the informal, friendly, but intense and some times heated exchanges that take place between workers in tackling very similar problems and systems and which are at the heart of every successful conference? Unfortunately this essence cannot be incorpo rated by soliciting manuscripts. For this reason, we have changed the format of publication, retaining published versions of the symposium papers, but requesting the workshop chairmen to produce a summary of the major new observations and areas of controversy highlighted in their sessions, as a vehicle for defining current areas of interest and debate. Not an easy task, as the workshop topics were culled from the abstracts submitted by the participants, rather than being on predefined topics. The unseasonal warmth in Cambridge was reflected in the atmos phere of the conference, the organization of which benefited from the administrative skills of Jean Bacon, Philippa Wells, Mr. Peter Irving, and Mrs.

Cytokine Frontiers

Takayuki Yoshimoto,Tomohiro Yoshimoto
Cytokine Frontiers Book PDF

Author : Takayuki Yoshimoto,Tomohiro Yoshimoto
Publisher : Springer Science & Business Media
Page : 398 pages
File Size : 53,9 Mb
Release : 2013-10-28
Category : Medical
ISBN : 9784431544425

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Cytokine Frontiers by Takayuki Yoshimoto,Tomohiro Yoshimoto Pdf

This book guides the reader through the latest research on the cytokine network, covering signaling pathways, control of the immune response, and potential therapeutics. Different cytokines stimulate diverse responses in various phases of inflammation and immunity, including the innate immune response, the generation of effector T cells, and the development of antibodies by the humoral immune system. It is now clear that the pathophysiology of many infectious, autoimmune, allergic, and malignant diseases can be largely explained by which cytokines are induced and subsequently regulate the cellular responses. In clinical medicine, cytokines are involved in a wide spectrum of diseases. This book describes in three parts the properties and roles of 15 key cytokines under physiological and pathological conditions. Part I presents nine cytokines associated with inflammatory disorders, pro-inflammatory cytokines, and the recently identified new helper T (Th) subset: Th17 cells. Part II gives details of three cytokines associated with allergic disorders, including Th2 responses and recently identified types of innate cells. Part III describes three cytokines that are associated with immunological tolerance and anti-inflammation, including regulatory T (Treg) cells, IL-10-producing Treg (Tr1) cells, and inducible IL-35-producing Treg (iTr35) cells. Cytokines are considered to be important as therapeutic targets for specific agonists or antagonists in numerous immune and inflammatory diseases. The ultimate goal of this book is to facilitate the development of therapeutic treatments for such diseases which has been limited by an insufficient understanding of the biology of cytokines and the complicated network that they create.

Immunology and Evolution of Infectious Disease

Steven A. Frank
Immunology and Evolution of Infectious Disease Book PDF

Author : Steven A. Frank
Publisher : Princeton University Press
Page : 364 pages
File Size : 43,9 Mb
Release : 2002-07-21
Category : Medical
ISBN : 0691095957

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Immunology and Evolution of Infectious Disease by Steven A. Frank Pdf

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Janeway's Immunobiology

Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter
Janeway s Immunobiology Book PDF

Author : Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter
Publisher : Garland Science
Page : 128 pages
File Size : 52,5 Mb
Release : 2010-06-22
Category : Medical
ISBN : 0815344570

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Janeway's Immunobiology by Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter Pdf

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.