Immunotoxicity Of Metals And Immunotoxicology

Author : International Program on Chemical Safety
Publisher : Springer
Page : 344 pages
File Size : 52,6 Mb
Release : 1990-11-30
Category : Health & Fitness
ISBN : UOM:39015019579732

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Immunotoxicity of Metals and Immunotoxicology by International Program on Chemical Safety Pdf

Considerable scientific and political interest has been expressed, parallelling public concern about the effects of chemicals on the immune system and the implications of those effects for health. Coupled with speculation about the magnitude and extent of the problem is discussion of needs for predictive testing and regulatory control measures. The first international seminar on the immunological system as a target for toxic damage was held in Luxembourg in 1984. It was organized by the International Programme on Chemical Safety (United Nations Environment Programme-International Labour Office World Health Organization) and the Commission of the European Communities with the support of the US Environmental Protection Agency and the National Institute of Environmental Health Sciences (USA) and the participation of the International Society of Immunopharmacology. In view of the perceived importance of imrnunotoxicity, it was considered necessary to organize a follow-up meeting. Thus, an international workshop on the immunotoxicity of metals and immuno toxicology was held in Hanover, Federal Republic of Germany, on 6-10 November 1989.

Author : Anthony Dayan,R.F. Hertel,E. Heseltine,G. Kazantis,E.B. Smith
Publisher : Springer
Page : 330 pages
File Size : 54,7 Mb
Release : 2012-12-02
Category : Medical
ISBN : 1468484451

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Immunotoxicity of Metals and Immunotoxicology by Anthony Dayan,R.F. Hertel,E. Heseltine,G. Kazantis,E.B. Smith Pdf

Considerable scientific and political interest has been expressed, parallelling public concern about the effects of chemicals on the immune system and the implications of those effects for health. Coupled with speculation about the magnitude and extent of the problem is discussion of needs for predictive testing and regulatory control measures. The first international seminar on the immunological system as a target for toxic damage was held in Luxembourg in 1984. It was organized by the International Programme on Chemical Safety (United Nations Environment Programme-International Labour Office World Health Organization) and the Commission of the European Communities with the support of the US Environmental Protection Agency and the National Institute of Environmental Health Sciences (USA) and the participation of the International Society of Immunopharmacology. In view of the perceived importance of imrnunotoxicity, it was considered necessary to organize a follow-up meeting. Thus, an international workshop on the immunotoxicity of metals and immuno toxicology was held in Hanover, Federal Republic of Germany, on 6-10 November 1989.

Author : Judith T Zelicoff,Peter Thomas
Publisher : CRC Press
Page : 385 pages
File Size : 49,9 Mb
Release : 1998-02-20
Category : Science
ISBN : 9780748403905

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Immunotoxicology Of Environmental And Occupational Metals by Judith T Zelicoff,Peter Thomas Pdf

Provides an overview of the effects of environmentally and occupationally important metals on the immune system and host defence. The fist ten chapters in the text focus on particular metals or groups of metals, including arsenic, beryllium, cadmium, chromium, lead, mercury, nickel and vanadium. Subsequent chapters examine the immunotoxicological effects of trace metals such as indium and platinum and essential metals such as iron, zinc and copper. The main emphasis is on the in vivo and in vitro effects of these metals on host immune responses in a variety of mammalian species including humans. Each chapter also briefly reviews the history, use, occurrence, biology and toxicology of the metals.

Author : Helen Tryphonas,Michel Fournier,Barry R. Blakley,Judit Smits,Pauline Brousseau
Publisher : CRC Press
Page : 788 pages
File Size : 47,7 Mb
Release : 2005-01-27
Category : Medical
ISBN : 9781134393992

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Investigative Immunotoxicology by Helen Tryphonas,Michel Fournier,Barry R. Blakley,Judit Smits,Pauline Brousseau Pdf

Investigative Immunotoxicology provides a critical evaluation of proposed experimental animal models and approaches, and discusses the contribution that immunotoxicity can make to the overall assessment of chemical-induced adverse health effects on humans and the ecosystem. Following a review of general concepts in immunotoxicology, the book discus

Author : Jacques Descotes
Publisher : Elsevier
Page : 400 pages
File Size : 44,5 Mb
Release : 2004-10-14
Category : Medical
ISBN : 9780080472997

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Principles and Methods of Immunotoxicology by Jacques Descotes Pdf

This is a review of clinical adverse effects on the human immune system that may occur following drug treatments and chemcical exposures. Current and prospective models and assays that can be used to predict these adverse effects in animal toxicity studies or in human beings are described.

Author : Jacques Descotes
Publisher : CRC Press
Page : 206 pages
File Size : 54,7 Mb
Release : 1998-12-09
Category : Medical
ISBN : 0748403078

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Introduction To Immunotoxicology by Jacques Descotes Pdf

This text provides a concise and comprehensive introduction to key immunotoxicological issues for all those interested in, but with no prior knowledge of, this area of toxicology. The first section explores the health consequences of immunotoxicity, namely the adverse effects related to chemically-induced immunosuppression and immunostimulation, hypersensitivity reactions and autoimmune diseases, with an overview of major immunotoxicants. The second part describes the latest methods used to detect and evaluate, preclinically and clinically, the unexpected immunotoxic effects of xenobiotics. Trends in implementing strategies and recent changes to the regulatory aspects are also considered. The third section examines possible future developments, including In Vitro methods, biomarkers of immunotixicity and risk assessment.

Author : Ralph J. Smialowicz,Michael P. Holsapple
Publisher : CRC Press
Page : 518 pages
File Size : 43,6 Mb
Release : 1996
Category : Business & Economics
ISBN : UOM:39015037261222

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Experimental Immunotoxicology by Ralph J. Smialowicz,Michael P. Holsapple Pdf

Immunotoxicology has emerged as a vital and expanding discipline over the past several years. Although the field of human immunotoxicology is arguably still in its infancy, a number of animal model systems have been well established and validated. Experimental Immunotoxicology provides an update on the recent advances in the field as it relates to animals and provokes discussion on approaches to the evaluation of human immunotoxicology. It is an important reference source for professionals in immunology and toxicology. The book begins with an overview of the mammalian immune system and covers the important role played by animal host susceptibility models. It also gives an update on immunotoxicolgy in sub-human primates. Vulnerability of bone marrow and the consequences of damage to immune function as well as chemical-induced immunosuppression as a consequence of exposure to chemicals are covered. Most of the chapters are organized to include a description of the profile of immunotoxicity, mechanisms of immunotoxicity, species comparisons and research needs.

Author : Jacques Descotes
Publisher : Elsevier Publishing Company
Page : 430 pages
File Size : 43,7 Mb
Release : 1986
Category : Medical
ISBN : UOM:39015010143694

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Immunotoxicology of Drugs and Chemicals by Jacques Descotes Pdf

Author : Monica Nordberg,Gunnar F. Nordberg,Bruce A. Fowler,Lars Friberg
Publisher : Elsevier
Page : 1024 pages
File Size : 51,5 Mb
Release : 2011-04-28
Category : Science
ISBN : 9780080546100

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Handbook on the Toxicology of Metals by Monica Nordberg,Gunnar F. Nordberg,Bruce A. Fowler,Lars Friberg Pdf

Handbook of the Toxicology of Metals is the standard reference work for physicians, toxicologists and engineers in the field of environmental and occupational health. This new edition is a comprehensive review of the effects on biological systems from metallic elements and their compounds. An entirely new structure and illustrations represent the vast array of advancements made since the last edition. Special emphasis has been placed on the toxic effects in humans with chapters on the diagnosis, treatment and prevention of metal poisoning. This up-to-date reference provides easy access to a broad range of basic toxicological data and also gives a general introduction to the toxicology of metallic compounds. * Covers up-to-date toxicological information on 31 metallic elements and their compounds, each in a separate chapter * New chapters on general chemistry, biological monitoring and biomarkers, essential metals, principles for prevention of the toxic effects of metals, and more

Author : Anonim
Publisher : Unknown
Page : 52 pages
File Size : 49,5 Mb
Release : 2004
Category : Chemical kinetics
ISBN : UIUC:30112104641862

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Issue Paper on the Human Health Effects of Metals by Anonim Pdf

Author : Jacques Descotes
Publisher : CRC Press
Page : 196 pages
File Size : 45,6 Mb
Release : 2003-09-02
Category : Medical
ISBN : 9780203362549

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Introduction To Immunotoxicology by Jacques Descotes Pdf

This text provides a concise and comprehensive introduction to key immunotoxicological issues for all those interested in, but with no prior knowledge of, this area of toxicology. The first section explores the health consequences of immunotoxicity, namely the adverse effects related to chemically-induced immunosuppression and immunostimulation, hypersensitivity reactions and autoimmune diseases, with an overview of major immunotoxicants. The second part describes the latest methods used to detect and evaluate, preclinically and clinically, the unexpected immunotoxic effects of xenobiotics. Trends in implementing strategies and recent changes to the regulatory aspects are also considered. The third section examines possible future developments, including In Vitro methods, biomarkers of immunotixicity and risk assessment.

Author : Michael J. Clarke,Peter J. Sadler
Publisher : Springer Science & Business Media
Page : 221 pages
File Size : 53,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642600616

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Metallopharmaceuticals II by Michael J. Clarke,Peter J. Sadler Pdf

Biological inorganic chemistry is a field of research at the interface of inorganic and biological chemistry. The rapidly developing insights into the role of metals in biological systems has far-reaching implications not only for biological science but also for related disciplines, ranging from molecular medicine to the environment. In each volume the reader, whether engaged in chemistry, biochemistry, biology or molecular medicine, receives a comprehensive summary and critical overview of a topic of hight current interest written by leading international experts.

Author : J. Turton,J. Hooson
Publisher : CRC Press
Page : 456 pages
File Size : 42,8 Mb
Release : 1997-10-06
Category : Medical
ISBN : 9780203481929

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Target Organ Pathology by J. Turton,J. Hooson Pdf

The major organs of the body are targets for chemically-induced effects in animals and humans. This book reviews the mechanisms of these toxic effects and the structure/functional changes which occur in the target organ tissues as a result.

Author : Robert A. Goyer
Publisher : Elsevier
Page : 550 pages
File Size : 46,6 Mb
Release : 2013-10-22
Category : Medical
ISBN : 9781483288567

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Metal Toxicology by Robert A. Goyer Pdf

Metal Toxicology addresses the effects of metals on human health, as well as their mechanisms of toxicity. Unlike most books on metal toxicity which are organized by individual metals, this book is arranged inan organ-by-organ basis. It deals with unifying mechanisms of metal toxicity within a given tissue, and with exposure of a tissue to more than one metal at a time. Unique aspect of organ-specific orientationWritten by leading authorities in metal toxicologyChapters of special interest include Risk Assessment, Emerging Technologies, and Molecular Biological TechniquesServes as an excellent sourcebook of generalized information on metal toxicology, allowing for specific tissue-system referencing

Author : D.J. Smith,William H. Gingerich,Maria G. Beconi-Barker
Publisher : Springer Science & Business Media
Page : 226 pages
File Size : 51,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461547037

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Xenobiotics in Fish by D.J. Smith,William H. Gingerich,Maria G. Beconi-Barker Pdf

Aquaculture is rapidly becoming a major source of fish protein used to meet the nutritional needs of humans. As the aquaculture industry grows, exposure of farmed fish to environmental contaminants, and the need for chemical therapeutic agents for fish, will increase. This book is designed to bring together authorities worldwide on the regulation of environmental contaminants and food chemicals and researchers investigating the metabolism and disposition of foreign chemicals (xenobiotics) in fish species.