Implication Of Quorum Sensing System In Biofilm Formation And Virulence

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Implication of Quorum Sensing System in Biofilm Formation and Virulence

Author : Pallaval Veera Bramhachari
Publisher : Springer
Page : 381 pages
File Size : 43,9 Mb
Release : 2019-01-28
Category : Medical
ISBN : 9789811324291

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Implication of Quorum Sensing System in Biofilm Formation and Virulence by Pallaval Veera Bramhachari Pdf

This book illustrates the importance and significance of Quorum sensing (QS), it’s critical roles in regulating diverse cellular functions in microbes, including bioluminescence, virulence, pathogenesis, gene expression, biofilm formation and antibiotic resistance. Microbes can coordinate population behavior with small molecules called autoinducers (AHL) which serves as a signal of cellular population density, triggering new patterns of gene expression for mounting virulence and pathogenesis. Therefore, these microbes have the competence to coordinate and regulate explicit sets of genes by sensing and communicating amongst themselves utilizing variety of signals. This book descry emphasizes on how bacteria can coordinate an activity and synchronize their response to external signals and regulate gene expression. The chapters of the book provide the recent advancements on various functional aspects of QS systems in different gram positive and gram negative organisms. Finally, the book also elucidates a comprehensive yet a representative description of a large number of challenges associated with quorum sensing signal molecules viz. virulence, pathogenesis, antibiotic synthesis, biosurfactants production, persister cells, cell signaling and biofilms, intra and inter-species communications, host-pathogen interactions, social interactions & swarming migration in biofilms.

Implication of Quorum Sensing and Biofilm Formation in Medicine, Agriculture and Food Industry

Author : Pallaval Veera Bramhachari
Publisher : Springer Nature
Page : 327 pages
File Size : 41,5 Mb
Release : 2019-11-26
Category : Medical
ISBN : 9789813294097

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Implication of Quorum Sensing and Biofilm Formation in Medicine, Agriculture and Food Industry by Pallaval Veera Bramhachari Pdf

The book illustrates the role of quorum sensing in the food industry, agriculture, veterinary sciences, and medicine. It highlights the importance of quorum sensing in regulating diverse cellular functions in microbes, including virulence, pathogenesis, controlled-gene expression systems, and antibiotic resistance. This book also describes the role of quorum sensing in survival behavior and antibiotic resistance in bacteria. Further, it reviews the major role played by quorum sensing in food spoilage, biofilm formation, and food-related pathogenesis. It also explores the methods for the detection and quantification of quorum sensing signals. It also presents antimicrobial and anti-quorum sensing activities of medicinal plants. Finally, the book elucidates a comprehensive yet representative description of basic and applied aspects of quorum sensing inhibitors. This book serves an ideal guide for researchers to understand the implications of quorum sensing in the food industry, medicine, and agriculture.

Implication of Quorum Sensing and Biofilm Formation in Medicine, Agriculture and Food Industry

Author : Pallaval Veera Bramhachari
Publisher : Unknown
Page : 0 pages
File Size : 44,7 Mb
Release : 2019
Category : Agriculture
ISBN : 9813294108

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Implication of Quorum Sensing and Biofilm Formation in Medicine, Agriculture and Food Industry by Pallaval Veera Bramhachari Pdf

The book illustrates the role of quorum sensing in the food industry, agriculture, veterinary sciences, and medicine. It highlights the importance of quorum sensing in regulating diverse cellular functions in microbes, including virulence, pathogenesis, controlled-gene expression systems, and antibiotic resistance. This book also describes the role of quorum sensing in survival behavior and antibiotic resistance in bacteria. Further, it reviews the major role played by quorum sensing in food spoilage, biofilm formation, and food-related pathogenesis. It also explores the methods for the detection and quantification of quorum sensing signals. It also presents antimicrobial and anti-quorum sensing activities of medicinal plants. Finally, the book elucidates a comprehensive yet representative description of basic and applied aspects of quorum sensing inhibitors. This book serves an ideal guide for researchers to understand the implications of quorum sensing in the food industry, medicine, and agriculture.

Quorum Sensing vs Quorum Quenching: A Battle with No End in Sight

Author : Vipin Chandra Kalia
Publisher : Springer
Page : 0 pages
File Size : 46,5 Mb
Release : 2016-08-23
Category : Science
ISBN : 8132235487

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Quorum Sensing vs Quorum Quenching: A Battle with No End in Sight by Vipin Chandra Kalia Pdf

Microbial relationships with all life forms can be as free living, symbiotic or pathogenic. Human beings harbor 10 times more microbial cells than their own. Bacteria are found on the skin surface, in the gut and other body parts. Bacteria causing diseases are the most worrisome. Most of the infectious diseases are caused by bacterial pathogens with an ability to form biofilm. Bacteria within the biofilm are up to 1000 times more resistant to antibiotics. This has taken a more serious turn with the evolution of multiple drug resistant bacteria. Health Departments are making efforts to reduce high mortality and morbidity in man caused by them. Bacterial Quorum sensing (QS), a cell density dependent phenomenon is responsible for a wide range of expressions such as pathogenesis, biofilm formation, competence, sporulation, nitrogen fixation, etc. Majority of these organisms that are important for medical, agriculture, aquaculture, water treatment and remediation, archaeological departments are: Aeromonas, Acinetobacter, Bacillus, Clostridia, Enterococcus, Pseudomonas, Vibrio and Yersinia spp. Biosensors and models have been developed to detect QS systems. Strategies for inhibiting QS system through natural and synthetic compounds have been presented here. The biotechnological applications of QS inhibitors (QSIs) in diverse areas have also been dealt with. Although QSIs do not affect growth and are less likely to impose selective pressure on bacteria, however, a few reports have raised doubts on the fate of QSIs. This book addresses a few questions. Will bacteria develop mechanisms to evade QSIs? Are we watching yet another defeat at the hands of bacteria? Or will we be acting intelligently and survive the onslaughts of this Never Ending battle?

Quorum Sensing

Author : Giuseppina Tommonaro
Publisher : Academic Press
Page : 310 pages
File Size : 41,7 Mb
Release : 2019-04-15
Category : Medical
ISBN : 9780128149058

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Quorum Sensing by Giuseppina Tommonaro Pdf

Quorum sensing (QS) is a process of bacterial cooperative behaviour that has an effect on gene regulation. This cell-to-cell communication system involves the production of signalling molecules according to cell density and growth stage. Virulence, the ability to infest a habitat and cause disease, is also governed by such communication signals. Quorum Sensing: Molecular mechanism and biotechnological application collects, describes and summarizes the most interesting results obtained from experts working on QS mechanisms. It contributes to the understanding of the molecular basis that regulates this mechanism, and describes new findings in fields of application. This volume describes the QS mechanism from its molecular basis to medical applications such as antibiotic therapy and involvement of QS in pathologies. This reference also analyzes its potential use in biotechnological applications such as food packaging, drug delivery, and marine biofilm. The broad scope of this title will be of significant use to researchers across several fields with interest in QS, including to microbiologists, chemists, biochemists and ecologists. Describes Quorum Sensing (QS) mechanisms from their molecular basis, to their clinical applications Spans several fields in relation to QS, including microbiology, chemistry, biochemistry and ecology Considers QS as an approach to the discovery of new antibiotics Looks at QS as a means to understand the microbial world and towards use of bacteria and their products in biotechnological applications Summarizes key results on QS mechanisms' molecular basis and fields of application

Fundamentals of, and Applications Based on, Quorum Sensing and Quorum Sensing Interference 

Author : Cristina García-Aljaro,Ana Otero,Tom Defoirdt
Publisher : Frontiers Media SA
Page : 269 pages
File Size : 44,7 Mb
Release : 2020-01-23
Category : Electronic
ISBN : 9782889633814

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Fundamentals of, and Applications Based on, Quorum Sensing and Quorum Sensing Interference  by Cristina García-Aljaro,Ana Otero,Tom Defoirdt Pdf

Background Bacteria use quorum sensing (QS) circuits to coordinate various activities (among which biofilm formation and the expression of virulence factors) based on the presence of signaling molecules. Different families of signal molecules have been identified in Gram positive and Gram negative bacteria (e.g. autoinducer peptides and acyl homoserine lactones). Similarly, different quorum sensing antagonists interfering with these system have been found in nature, promoting a new and promising field of research, quorum sensing interference. One of the most intensively studied applications of quorum sensing interference is its use as an alternative or synergycally with antibiotics to fight (antibiotic-resistant) bacterial pathogens. Many studies have been published claiming quorum sensing inhibitory activity of natural and synthetic compounds. However, after decades of research, several questions regarding the suitability of this approach to fight bacterial pathogens remain unanswered, including the risk that pathogens will develop resistance against quorum quenching. Meanwhile, the interest in quorum sensing has increased considerably, and this has broadened the fields where it can find biotechnological, environmental and industrial applications, such as anti biofouling, steering fermentations, bioremediation and wastewater treatment. Goal and scope The goal of this Research Topic is to broaden the knowledge of the phenotypes regulated by quorum sensing and the advances in quorum sensing interference. Deciphering microorganism language and the different phenotypes regulated by microbial signalling systems is a frontier for the development of new tools for the management of microorganisms to fulfil human needs with a broad application in different areas such as medicine, environmental sciences and industry.

Bacterial Signal Transduction: Networks and Drug Targets

Author : Ryutaro Utsumi
Publisher : Springer Science & Business Media
Page : 257 pages
File Size : 47,6 Mb
Release : 2008-12-05
Category : Medical
ISBN : 9780387788852

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Bacterial Signal Transduction: Networks and Drug Targets by Ryutaro Utsumi Pdf

This fascinating book encourages many microbiologists and students to enter the new world of signal transduction in microbiology. Over the past decade, a vast amount of exciting new information on the signal transduction pathway in bacteria has been unearthed.

Trends in Quorum Sensing and Quorum Quenching

Author : V. Ravishankar Rai,Jamuna A Bai
Publisher : CRC Press
Page : 628 pages
File Size : 53,6 Mb
Release : 2020-05-04
Category : Science
ISBN : 9781000051490

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Trends in Quorum Sensing and Quorum Quenching by V. Ravishankar Rai,Jamuna A Bai Pdf

The book on Trends in Quorum Sensing and Quorum Quenching: New Perspectives and Applications focuses on the recent advances in the field of quorum sensing in bacteria and the novel strategies developed for quorum sensing inhibition. The topics covered are multidisciplinary and wide-ranging,and includes quorum sensing phenomenon in pathogenic bacteria, food spoilers, and agriculturally relevant bacteria. The applications of quorum sensing inhibitors such as small molecules, bioactives, natural compounds, and quorum quenching enzymes in controlling bacterial infections in clinical settings, agriculture and aquaculture are discussed. The potential use of quorum quenching enzymes for mitigating biofouling is also covered. Special focus is given to exploring quorum sensing inhibitors from microbes and flora inhabiting biodiversity rich regions including tropical rain forests and marine environments. Key features: Covers the fundamental aspects, the progress and challenges in the field of quorum sensing and quorum quenching Reviews quorum sensing in Gram-positive and Gram-negative bacteria of clinical, agricultural, and industrial relevance Discusses the application and future trends of quorum sensing inhibitors from lab to clinical and environmental settings Provides comprehensive coverage on molecular mechanisms in bacterial signaling

Bacterial Biofilms

Author : Tony Romeo
Publisher : Springer Science & Business Media
Page : 302 pages
File Size : 43,9 Mb
Release : 2008-02-26
Category : Medical
ISBN : 9783540754183

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Bacterial Biofilms by Tony Romeo Pdf

Throughout the biological world, bacteria thrive predominantly in surface-attached, matrix-enclosed, multicellular communities or biofilms, as opposed to isolated planktonic cells. This choice of lifestyle is not trivial, as it involves major shifts in the use of genetic information and cellular energy, and has profound consequences for bacterial physiology and survival. Growth within a biofilm can thwart immune function and antibiotic therapy and thereby complicate the treatment of infectious diseases, especially chronic and foreign device-associated infections. Modern studies of many important biofilms have advanced well beyond the descriptive stage, and have begun to provide molecular details of the structural, biochemical, and genetic processes that drive biofilm formation and its dispersion. There is much diversity in the details of biofilm development among various species, but there are also commonalities. In most species, environmental and nutritional conditions greatly influence biofilm development. Similar kinds of adhesive molecules often promote biofilm formation in diverse species. Signaling and regulatory processes that drive biofilm development are often conserved, especially among related bacteria. Knowledge of such processes holds great promise for efforts to control biofilm growth and combat biofilm-associated infections. This volume focuses on the biology of biofilms that affect human disease, although it is by no means comprehensive. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental, and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth.

Bacterial Cell-to-Cell Communication

Author : Donald R. Demuth,Richard Lamont
Publisher : Cambridge University Press
Page : 340 pages
File Size : 45,5 Mb
Release : 2006-02-23
Category : Science
ISBN : 1139447971

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Bacterial Cell-to-Cell Communication by Donald R. Demuth,Richard Lamont Pdf

Many bacterial diseases are caused by organisms growing together as communities or biofilms. These microorganisms have the capacity to coordinately regulate specific sets of genes by sensing and communicating amongst themselves utilizing a variety of signals. This book examines the mechanisms of quorum sensing and cell-to-cell communication in bacteria and the roles that these processes play in regulating virulence, bacterial interactions with host tissues, and microbial development. Recent studies suggest that microbial cell-to-cell communication plays an important role in the pathogenesis of a variety of disease processes. Furthermore, some bacterial signal molecules may possess immunomodulatory activity. Thus, understanding the mechanisms and outcomes of bacterial cell-to-cell communication has important implications for appreciating host-pathogen interactions and ultimately may provide new targets for antimicrobial therapies that block or interfere with these communication networks.

Advances in Aquaculture Hatchery Technology

Author : Geoff Allan,Gavin Burnell
Publisher : Elsevier
Page : 682 pages
File Size : 52,8 Mb
Release : 2013-02-19
Category : Technology & Engineering
ISBN : 9780857097460

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Advances in Aquaculture Hatchery Technology by Geoff Allan,Gavin Burnell Pdf

Aquaculture is the fastest-growing food production sector in the world. With demand for seafood increasing at astonishing rates, the optimization of production methods is vital. One of the primary restrictions to continued growth is the supply of juveniles from hatcheries. Addressing these constraints, Advances in aquaculture hatchery technology provides a comprehensive, systematic guide to the use of current and emerging technologies in enhancing hatchery production.Part one reviews reproduction and larval rearing. Aquaculture hatchery water supply and treatment systems, principles of finfish broodstock management, genome preservation, and varied aspects of nutrition and feeding are discussed in addition to larval health management and microbial management for bacterial pathogen control. Closing the life-cycle and overcoming challenges in hatchery production for selected invertebrate species are the focus of part two, and advances in hatchery technology for spiny lobsters, shrimp, blue mussel, sea cucumbers and cephalopods are all discussed. Part three concentrates on challenges and successes in closing the life-cycle and hatchery production for selected fish species, including tuna, striped catfish, meagre, and yellowtail kingfish. Finally, part four explores aquaculture hatcheries for conservation and education.With its distinguished editors and international team of expert contributors, Advances in aquaculture hatchery technology is an authoritative review of the field for hatchery operators, scientists, marine conservators and educators. Provides a comprehensive guide to the use of technologies in enhancing hatchery production Examines reproduction and larval rearing, including genetic improvement and microdiets Discusses challenges in hatchery production of specific species

Quorum Sensing

Author : Saurabh Sudha Dhiman
Publisher : Unknown
Page : 308 pages
File Size : 48,9 Mb
Release : 2021
Category : Science
ISBN : 0841298602

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Quorum Sensing by Saurabh Sudha Dhiman Pdf

New developments in researching quorum sensing Microbial growth affects industries as diverse as agriculture, engineering, and medicine, to name a few. As more precise solutions are needed for modern challenges, researchers must understand the mechanisms of microbial growth. Quorum sensing (QS) is an essential part of microbial growth, and this work contains key areas such as signal molecules; mechanisms of signal transfer, role, and type of signal receptors; quorum quenching; characterization of microbial plasmids in quorum sensing; and novel and underexplored molecules involved in QS, along with therapeutic roles of quorum sensing inhibitors. This volume is perfect for researchers working on microbiology or biotechnology.

Bacterial Biofilms

Author : Sadik Dincer,Melis Sümengen Özdenefe,Afet Arkut
Publisher : BoD – Books on Demand
Page : 362 pages
File Size : 51,8 Mb
Release : 2020-10-07
Category : Science
ISBN : 9781789858990

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Bacterial Biofilms by Sadik Dincer,Melis Sümengen Özdenefe,Afet Arkut Pdf

This book examines biofilms in nature. Organized into four parts, this book addresses biofilms in wastewater treatment, inhibition of biofilm formation, biofilms and infection, and ecology of biofilms. It is designed for clinicians, researchers, and industry professionals in the fields of microbiology, biotechnology, ecology, and medicine as well as graduate and postgraduate students.

Microbial Biofilms

Author : Mahmoud Ghannoum,Matthew Parsek,Marvin Whiteley,Pranab K. Mukherjee
Publisher : John Wiley & Sons
Page : 608 pages
File Size : 55,6 Mb
Release : 2015-10-01
Category : Science
ISBN : 9781683673330

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Microbial Biofilms by Mahmoud Ghannoum,Matthew Parsek,Marvin Whiteley,Pranab K. Mukherjee Pdf

An examination of the research and translational application to prevent and treat biofilm-associated diseases In the decade since the first edition of Microbial Biofilms was published, the interest in this field has expanded, spurring breakthrough research that has advanced the treatment of biofilm-associated diseases. This second edition takes the reader on an exciting, extensive review of bacterial and fungal biofilms, ranging from basic molecular interactions to innovative therapies, with particular emphasis on the division of labor in biofilms, new approaches to combat the threat of microbial biofilms, and how biofilms evade the host defense. Chapters written by established investigators cover recent findings, and contributions from investigators new to the field provide unique and fresh insights. Specifically, Microbial Biofilms provides state-of-the-art research in the field of bacterial and fungal biofilms detailed descriptions of the in vitro and in vivo models available to evaluate microbial biofilms future areas of research and their translational and clinical applications Microbial Biofilms is a useful reference for researchers and clinicians. It will also provide insight in the dynamic field of microbial biofilms for graduate and postgraduate students.

Bacterial Signaling

Author : Reinhard Krämer,Kirsten Jung
Publisher : John Wiley & Sons
Page : 513 pages
File Size : 49,9 Mb
Release : 2009-12-09
Category : Science
ISBN : 9783527629244

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Bacterial Signaling by Reinhard Krämer,Kirsten Jung Pdf

Providing a comprehensive insight into cellular signaling processes in bacteria with a special focus on biotechnological implications, this is the first book to cover intercellular as well as intracellular signaling and its relevance for biofilm formation, host pathogen interactions, symbiotic relationships, and photo- and chemotaxis. In addition, it deals in detail with principal bacterial signaling mechanisms -- making this a valuable resource for all advanced students in microbiology. Dr. Krämer is a world-renowned expert in intracellular signaling and its implications for biotechnology processes, while Dr. Jung is an expert on intercellular signaling and its relevance for biomedicine and agriculture.