Integrative Neuroscience And Personalized Medicine

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Integrative Neuroscience and Personalized Medicine

Evian Gordon,Stephen Koslow, PhD
Integrative Neuroscience and Personalized Medicine Book PDF

Author : Evian Gordon,Stephen Koslow, PhD
Publisher : Oxford University Press
Page : 346 pages
File Size : 42,5 Mb
Release : 2011
Category : Language Arts & Disciplines
ISBN : 9780195393804

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Integrative Neuroscience and Personalized Medicine by Evian Gordon,Stephen Koslow, PhD Pdf

This book takes an in depth and hard look at the current status and future direction of treatment predictive markers in Personalized Medicine for the brain from the perspectives of the researchers on the cutting edge and those involved in healthcare implementation. The contents provide a comprehensive text suitable as both a pithy introduction to and a clear summary of the "science to solutions" continuum in this developing field of Personalized Medicine and Integrative Neuroscience. The science includes both measures of genes using whole genome approaches and SNIPS as well as BRAINmarkers of direct brain function such as brain imaging, biophysical changes and objective cognitive and behavioral measurements. Personalized Medicine for Brain Disorders will soon be a reality using the comprehensive quantitative and standardized approaches to genomics, BRAINmarkers and cognitive function. Each chapter provides a review of recent relevant literature; show the solutions achieved through integrative neuroscience and applications in patient care thus providing a practical guide to the reader. The timeliness of this book's content is propitious providing bottom line information to educate practicing clinicians, health care workers and researchers, and also a pathway for undergraduate and graduates interested in further their understanding of and involvement in tailored personal solutions.

Personalized Medicine in Neuroscience: Molecular to System Approach

Ali Yadollahpour,Ti-Fei Yuan,Sergio Machado
Personalized Medicine in Neuroscience Molecular to System Approach Book PDF

Author : Ali Yadollahpour,Ti-Fei Yuan,Sergio Machado
Publisher : Frontiers Media SA
Page : 169 pages
File Size : 45,7 Mb
Release : 2024-04-17
Category : Science
ISBN : 9782832541272

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Personalized Medicine in Neuroscience: Molecular to System Approach by Ali Yadollahpour,Ti-Fei Yuan,Sergio Machado Pdf

Personalized or precision medicine (PM) is developing and adopting of the safest and most cost-effective therapeutic approach for each patient. PM approach aims to identify phenotypic and genotypic individual characteristics, observe how these parameters are correlated with the disease status, severity, and intervention responsiveness to predict the best personalized clinical protocol. On the other hand, the risk of severe toxicity and adverse effects might be related to the patient-specific characteristics.

Pediatricians and Pharmacologically Trained Psychologists

George M. Kapalka
Pediatricians and Pharmacologically Trained Psychologists Book PDF

Author : George M. Kapalka
Publisher : Springer Science & Business Media
Page : 303 pages
File Size : 42,8 Mb
Release : 2011-01-20
Category : Medical
ISBN : 9781441977809

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Pediatricians and Pharmacologically Trained Psychologists by George M. Kapalka Pdf

Many factors affect treatment options for children and adolescents with mental health problems, including age, severity of symptoms, financial and time constraints, and access to qualified professionals. With the limitations of managed care plans and the shrinking pool of pediatric psychiatrists, the trend is toward pediatricians prescribing psychotropic medicines. Pharmacologically trained psychologists can offer valuable assistance to pediatricians caught in this predicament. Tackling fundamental questions of when to treat as well as when and why to refer young patients, the Pediatricians and Pharmacologically Trained Psychologists examines commonly occurring pediatric conditions requiring joint treatment; reviews theoretical models of consultation and collaboration; and spotlights professional issues typically arising from these team efforts. With pertinent clarity and detail, this volume offers in-depth discussion in these key areas: Collaborative treatment of mental health conditions, including mood, disruptive, anxiety, and eating disorders. Collaborative treatment of medical conditions, focusing on gastrointestinal disorders and diabetes. Changing clinical procedures in states that have enacted prescriptive authority for psychologists. Expanding roles for pharmacologically trained psychologists practicing in states that have not enacted prescriptive authority for psychologists. Medical psychology in the pediatric hospital. Integrative care in rural settings and on the reservation. The collaborative future: brain marker technology, training paradigms, and more. Pediatricians and Pharmacologically Trained Psychologists is a must-have reference for a broad range of researchers, professionals, and graduate students, including psychologists, pediatricians and other child mental health clinicians as well as nonphysician prescribers, such as nurses, physician assistants, and pharmacists.

Psychoneuroimmunology

Qing Yan
Psychoneuroimmunology Book PDF

Author : Qing Yan
Publisher : Springer
Page : 136 pages
File Size : 44,7 Mb
Release : 2016-10-03
Category : Medical
ISBN : 9783319451114

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Psychoneuroimmunology by Qing Yan Pdf

This book provides a comprehensive overview of the cutting-edge discoveries and the systems approaches related to the multi-disciplinary field of psychoneuroimmunology (PNI), which may provide the scientific basis for mind-body relationships, and aid in the development of personalized medicine. Specifically, the book focuses on the systems biology studies of complex mechanisms, such as stress and inflammation. There is strong evidence supporting the close relationship between stress, inflammation, and disorders including obesity, cardiovascular disease, diabetes, skin diseases, and sleep disorders. As inflammation is a critical connection among different diseases, further elucidating this connection may contribute to the findings of systemic therapeutic targets. Translational medicine is also addressed, by applying PNI approaches in clinical practice. A major challenge in current bioscience is the translation of basic scientific discoveries into better clinical outcomes. With the understanding of the translational implications of PNI, integrative interventions can be applied to modulate stress responses and to promote healthier behaviors. As an important feature of this book, a broad overview of the PNI-associated integrative interventions is provided. These interventions include nutritional supplements, meditation, and other mind-body strategies. From basic concepts to systems methodologies, from theoretical sources to clinical applications, Psychoneuroimmunology contributes to the understanding and development of PNI toward the establishment of personalized and mind-body medicine.

Neurodegenerative Diseases: Integrative PPPM Approach as the Medicine of the Future

Silvia Mandel
Neurodegenerative Diseases Integrative PPPM Approach as the Medicine of the Future Book PDF

Author : Silvia Mandel
Publisher : Springer Science & Business Media
Page : 402 pages
File Size : 48,5 Mb
Release : 2013-03-12
Category : Medical
ISBN : 9789400758667

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Neurodegenerative Diseases: Integrative PPPM Approach as the Medicine of the Future by Silvia Mandel Pdf

This book will compile a collection of chapters dedicated to varied aspects of PPPM in neuropsychiatric and neurodegenerative diseases. Among the topics to be covered are: Recent advances in ALS research News about Clinical aspects and advanced therapy approaches in personalized treatment of ALS Schizophrenia: New treatments and clinical aspects Predictive, Preventive and Personalised Medicine in aging macular degeneration Advances in Multiple Sclerosis Pharmacogenetics, Tailoring Treatment Efficacy, Safety and Regimen Selection Multiple sclerosis related biomarkers: perspectives for clinical application Preventive clinical trials in brain aging: new trends & the need of guidelines MCI_ clinical guidelines in early diagnosis of dementia Alzheimer's disease: diagnostics, prognostics and the road to prevention Biomarkers for early diagnosis of Parkinson's and Alzheimer's diseases Synucleinopathies, tauopathies, TDP-43 proteinopathies and amyloidosis PSP, MSA and other parkinsonisms

Engineering-Medicine

Lawrence S. Chan,William C. Tang
Engineering Medicine Book PDF

Author : Lawrence S. Chan,William C. Tang
Publisher : CRC Press
Page : 420 pages
File Size : 44,9 Mb
Release : 2019-05-15
Category : Medical
ISBN : 9781351012256

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Engineering-Medicine by Lawrence S. Chan,William C. Tang Pdf

This transformative textbook, first of its kind to incorporate engineering principles into medical education and practice, will be a useful tool for physicians, medical students, biomedical engineers, biomedical engineering students, and healthcare executives. The central approach of the proposed textbook is to provide principles of engineering as applied to medicine and guide the medical students and physicians in achieving the goal of solving medical problems by engineering principles and methodologies. For the medical students and physicians, this proposed textbook will train them to “think like an engineer and act as a physician”. The textbook contains a variety of teaching techniques including class lectures, small group discussions, group projects, and individual projects, with the goals of not just helping students and professionals to understand the principles and methods of engineering, but also guiding students and professionals to develop real-life solutions. For the biomedical engineers and biomedical engineering students, this proposed textbook will give them a large framework and global perspective of how engineering principles could positively impact real-life medicine. To the healthcare executives, the goal of this book is to provide them general guidance and specific examples of applying engineering principles in implementing solution-oriented methodology to their healthcare enterprises. Overall goals of this book are to help improve the overall quality and efficiency of healthcare delivery and outcomes.

The Road from Nanomedicine to Precision Medicine

Shaker. A Mousa,Raj Bawa,Gerald F. Audette
The Road from Nanomedicine to Precision Medicine Book PDF

Author : Shaker. A Mousa,Raj Bawa,Gerald F. Audette
Publisher : CRC Press
Page : 646 pages
File Size : 45,5 Mb
Release : 2020-01-06
Category : Medical
ISBN : 9781000043327

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The Road from Nanomedicine to Precision Medicine by Shaker. A Mousa,Raj Bawa,Gerald F. Audette Pdf

The enormous advances in nanomedicine and precision medicine in the past two decades necessitated this comprehensive reference, which can be relied upon by researchers, clinicians, pharmaceutical scientists, regulators, policymakers, and lawyers alike. This standalone, full-color resource broadly surveys innovative technologies and advances pertaining to nanomedicine and precision medicine. In addition, it addresses often-neglected yet crucial areas such as translational medicine, intellectual property law, ethics, policy, FDA regulatory issues, nano-nomenclature, and artificial nano-machines—all accomplished in a user-friendly, broad yet interconnected format. The book is essential reading for the novice and the expert alike in diverse fields such as medicine, law, pharmacy, genomics, biomedical sciences, ethics, and regulatory science. The book’s multidisciplinary approach will attract a global audience and serve as a valuable reference resource for industry, academia, and government.

Integrative Neuroscience

Evian Gordon
Integrative Neuroscience Book PDF

Author : Evian Gordon
Publisher : CRC Press
Page : 269 pages
File Size : 50,5 Mb
Release : 2003-09-02
Category : Science
ISBN : 9780203304761

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Integrative Neuroscience by Evian Gordon Pdf

Most brain related activity has focussed on specialized interests within individual disciplines. Recent multidisciplinary activity has provided the impetus to break down these boundaries and encourage a freer exchange of information across disciplines. This text reflects these developments. It spans the landscape of brain science to provide core information from 12 disciplines (including evolution, philosophy, anatomy, chemistry, computer science, brain dynamics, psychology, neurology, psychiatry, psychotherapy and brain imaging). In outlining how and why it is now possible to realistically model aspects of the brain's dynamics from such a wide range of intellectual endeavors, this book will prove itself useful to undergraduates, postgraduates and all those seeking a contemporary perspective and evaluation of the current status and future directions in the brain sciences.

Personalized Medicine

Gloria Gronowicz
Personalized Medicine Book PDF

Author : Gloria Gronowicz
Publisher : CRC Press
Page : 212 pages
File Size : 46,6 Mb
Release : 2016-04-05
Category : Medical
ISBN : 9781498714921

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Personalized Medicine by Gloria Gronowicz Pdf

Personalized Medicine: Promises and Pitfalls broadly explores the tailoring of medical treatment to a patient’s characteristics, needs, and preferences during all stages of care, including prevention, diagnosis, treatment, and follow-up. The book’s goal is to explain the science behind personalized medicine, what impact it may have on specific diseases, and some of the repercussions of a personalized medical approach on our medical institutions. Novel personalized therapeutic treatments and their scientific basis are discussed by covering topics as diverse as genomics, proteomics, epigenetics, integrative medicine, stem cells, and the factors that influence personal health. A personalized medical system also requires patient involvement in developing a healthy lifestyle, and so this book touches on topics such as the individual’s family history, present and past lifestyle, nutrition, exercise levels, and stress factors. By explaining these broad topics in personalized medicine and the science behind them, we discover how personalized medicine can have a positive impact on an individual’s health.

Middleton's Allergy E-Book

A Wesley Burks,Stephen T Holgate,Robyn E O'Hehir,Leonard B. Bacharier,David H. Broide,Gurjit K. Khurana Hershey,R. Stokes Peebles, Jr.
Middleton s Allergy E Book Book PDF

Author : A Wesley Burks,Stephen T Holgate,Robyn E O'Hehir,Leonard B. Bacharier,David H. Broide,Gurjit K. Khurana Hershey,R. Stokes Peebles, Jr.
Publisher : Elsevier Health Sciences
Page : 1840 pages
File Size : 45,6 Mb
Release : 2019-09-25
Category : Medical
ISBN : 9780323546980

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Middleton's Allergy E-Book by A Wesley Burks,Stephen T Holgate,Robyn E O'Hehir,Leonard B. Bacharier,David H. Broide,Gurjit K. Khurana Hershey,R. Stokes Peebles, Jr. Pdf

Through eight outstanding editions, Middleton’s Allergy: Principles and Practice has been the reference of choice for both clinicians and researchers as both a practical reference and an effective self-assessment tool for board preparation. The 9th Edition continues the tradition of excellence with comprehensive coverage of all basic science and clinical applications regarding allergy practice and disease mechanisms. It brings you fully up to date with recent innovations in the diagnosis, prevention, and management of allergic disorders, including emerging global issues, the advent of precision medicine, and new immunologic therapies. Offers unparalleled depth and up-to-date guidance on the full spectrum of allergy across the lifespan, with significant updates throughout. Contains new chapters on Innate Lymphoid Cells, Systems Biology, and Treatment of Primary Immunodeficiency Diseases. Discusses emerging topics such as epidemic thunderstorm asthma and precision medicine in allergic disorders. Features more than 730 full-color illustrations, including many new cellular and molecular drawings of disease mechanisms. Includes new Summary of Important Concepts boxes, plus new multiple-choice questions online with explanations and answers. Features a new team of expert editors and more international contributors for a global perspective of this complex field.

Precision Medicine in Neurodegenerative Disorders

Anonim
Precision Medicine in Neurodegenerative Disorders Book PDF

Author : Anonim
Publisher : Elsevier
Page : 290 pages
File Size : 40,7 Mb
Release : 2023-02-14
Category : Medical
ISBN : 9780323900645

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Precision Medicine in Neurodegenerative Disorders by Anonim Pdf

Precision Medicine in Neurodegenerative Disorders, Part One, Volume 192 in the Handbook of Clinical Neurology deals with the "Why" in the approach to slow the progression of accelerated brain aging. This volume is intended to provide a scholarly background on the framework, basic science and conceptual pitfalls related to disease-modifying efforts in Parkinson's, Alzheimer's and other neurodegenerative disorders. Among topics covered are different models of precision medicine, the lumping-versus-splitting tension in biomarker development and therapeutics, and the rationale for replacing the convergence of the prevailing autopsy-based nosology of neurodegenerative diseases with the divergence of a systems biology approach to human diseases. Specific chapters are dedicated to the promise of genetic subtypes and the lessons in disease modification offered by the fields of oncology and cystic fibrosis that can be adapted to the field of neurodegeneration. Matching a biology-correcting therapy with those biologically suitable to benefit from such therapy represents the vision and mission of precision medicine, the highest level of personalized medicine. Summarizes theory and research on precision medicine in neurodegenerative disorders Covers basic biology, clinical trials and therapeutics Includes disease mechanisms, genetic subtypes, and more

Integrative Neuroscience

Evian Gordon
Integrative Neuroscience Book PDF

Author : Evian Gordon
Publisher : Unknown
Page : 272 pages
File Size : 53,8 Mb
Release : 2002
Category : MEDICAL
ISBN : 0367807661

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Integrative Neuroscience by Evian Gordon Pdf

Most brain related activity has focussed on specialized interests within individual disciplines. Recent multidisciplinary activity has provided the impetus to break down these boundaries and encourage a freer exchange of information across disciplines. This text reflects these developments. It spans the landscape of brain science to provide core information from 12 disciplines (including evolution, philosophy, anatomy, chemistry, computer science, brain dynamics, psychology, neurology, psychiatry, psychotherapy and brain imaging).In outlining how and why it is now possible to realistically model aspects of the brain's dynamics from such a wide range of intellectual endeavors, this book will prove itself useful to undergraduates, postgraduates and all those seeking a contemporary perspective and evaluation of the current status and future directions in the brain sciences.

Topics in Integrative Neuroscience

James R. Pomerantz
Topics in Integrative Neuroscience Book PDF

Author : James R. Pomerantz
Publisher : Cambridge University Press
Page : 0 pages
File Size : 51,9 Mb
Release : 2010-06-10
Category : Medical
ISBN : 0521143403

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Topics in Integrative Neuroscience by James R. Pomerantz Pdf

Neuroscience is progressing so rapidly that even expressions such as 'by leaps and bounds' fail to capture the pace of its growth. Questions that once were thought to be unanswerable - perhaps even unaskable - have been both asked and answered, and questions once unthinkable, are routine. Topics in Integrative Neuroscience has singled out four of the most important problems in neuroscience: higher order perception; language; memory systems; and sensory processes. The volume presents original contributions by many of the leading researchers in those fields, and with an initial chapter covering neuroethics. It is impossible to capture fully the sweep of discoveries that emerged from the 'Decade of the Brain' within the covers of a single volume. It is possible, however, to provide a sample, both in recognition of what has been accomplished and as a harbinger of what is surely to come.

Integrative Medicine and the Health of the Public

Institute of Medicine
Integrative Medicine and the Health of the Public Book PDF

Author : Institute of Medicine
Publisher : National Academies Press
Page : 245 pages
File Size : 44,9 Mb
Release : 2009-10-16
Category : Medical
ISBN : 9780309147316

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Integrative Medicine and the Health of the Public by Institute of Medicine Pdf

The last century witnessed dramatic changes in the practice of health care, and coming decades promise advances that were not imaginable even in the relatively recent past. Science and technology continue to offer new insights into disease pathways and treatments, as well as mechanisms of protecting health and preventing disease. Genomics and proteomics are bringing personalized risk assessment, prevention, and treatment options within reach; health information technology is expediting the collection and analysis of large amounts of data that can lead to improved care; and many disciplines are contributing to a broadening understanding of the complex interplay among biology, environment, behavior, and socioeconomic factors that shape health and wellness. On February 25 - 27, 2009, the Institute of Medicine (IOM) convened the Summit on Integrative Medicine and the Health of the Public in Washington, DC. The summit brought together more than 600 scientists, academic leaders, policy experts, health practitioners, advocates, and other participants from many disciplines to examine the practice of integrative medicine, its scientific basis, and its potential for improving health. This publication summarizes the background, presentations, and discussions that occurred during the summit.

Toward Precision Assessment and Psychotherapy: Understanding Individual Differences Through Neurobiology, Genetics, and Epigenetics

Thomas G. Arizmendi, Ph.d.
Toward Precision Assessment and Psychotherapy Understanding Individual Differences Through Neurobiology Genetics and Epigenetics Book PDF

Author : Thomas G. Arizmendi, Ph.d.
Publisher : Unknown
Page : 128 pages
File Size : 50,5 Mb
Release : 2020-02-12
Category : Electronic
ISBN : 1536165360

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Toward Precision Assessment and Psychotherapy: Understanding Individual Differences Through Neurobiology, Genetics, and Epigenetics by Thomas G. Arizmendi, Ph.d. Pdf

This book provides a transformative approach to the understanding of mental health in the 21st century. It does so by encouraging the replacement of traditional subjective techniques with more precise and objective measures that are designed to discover individual differences in our patients. Just as in personalised medicine, where diagnostic and treatment techniques are becoming more targeted toward the specific conditions of a particular patient, so to in the mental health field we need to develop targeted and focused methods through the use of clinical science concepts and through the adoption of an agnostic, unassuming posture where the presentation of each patient is viewed as unique. For example, treatments may draw from an integrative approach that incorporates genomic and epigenomic analyses of the patient to inform a more targeted medication regimen or psychotherapy approach (some psychiatrists are beginning to use genomic analysis to aid in the choice of a specific antidepressant, for example, that would most likely be effective for a certain patient). Diagnostically, paper and pencil questionnaires leading to current diagnostic labels, long the standard, must be replaced, for the most part, by objective measures of stress that prioritise "reports from the body". Additionally, research methods of extremely complex psychological disorders can be enhanced by breaking them down into smaller subtypes (or endophenotypes) versus large phenomenologically-based symptom clusters (ie: DSM diagnoses). Individual differences, a consistent focus throughout the book, may be the product of genetic variants and/or epigenetic mechanisms. The latter mediate gene X environment interaction that is now the primary paradigmatic lens through which we investigate and seek to explain resultant behavioural profiles. A major focus of the book is on the effects of early adversity, particularly trauma, and how they contribute to a "re-programming" of the brain through epigenetic alterations of gene expression. This results in increased vulnerability to possible psychological disorders, such as various anxiety conditions, depression, and character disorders which may manifest later in life. By identifying the epigenetic effects caused by early stressors, that is, how gene expression is altered, we can eventually make significant advances in primary prevention. This book represents an attempt to move us into a transitional domain and beyond, where causes and the treatment of psychological disorders are re-conceptualized through our developing insights from neurobiology, genetics, and epigenetics.