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Interaction Of Biomolecules And Bioactive Compounds With The Sars Cov 2 Proteins Molecular Simulations For The Fight Against Covid 19 Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Interaction Of Biomolecules And Bioactive Compounds With The Sars Cov 2 Proteins Molecular Simulations For The Fight Against Covid 19 book. This book definitely worth reading, it is an incredibly well-written.
Author : Mattia Falconi,Arvind Ramanathan,James Leland Olds
Publisher : Frontiers Media SA
Page : 129 pages
File Size : 46,6 Mb
Release : 2022-07-18
Category : Science
ISBN : 9782889765751
Author : Jen-Tsung Chen
Publisher : CRC Press
Page : 681 pages
File Size : 52,7 Mb
Release : 2023-09-26
Category : Medical
ISBN : 9781000909098
Coronaviruses can cause illness, severe disease, and death; for example, Middle East respiratory syndrome (MERS), severe acute respiratory syndrome (SARS), and COVID-19. Vaccine development and antiviral drugs are challenged by the propensity for viral mutations allowing these viruses to evade such therapies. There are a number of bioactive compounds from natural sources, which can exert health benefits and act as antiviral therapies such as anti-inflammation, antioxidative stress, and immune regulation. This book summarizes research on the potential efficacy and underlying mechanisms of bioactive compounds and traditional medicines against SARS-CoV-2. Key Features Summarizes the potential benefits of bioactive therapies for coronaviruses Focuses on COVID-19, but also covers MERS and SARS Provides alternatives to vaccines and other antiviral drugs whose efficacy is reduced by viral mutations Relevant for clinicians and public health officials
Author : Emilia Pedone,Domenica Capasso,Sonia Di Gaetano,Chandrabose Selvaraj
Publisher : Frontiers Media SA
Page : 251 pages
File Size : 40,6 Mb
Release : 2021-10-20
Category : Science
ISBN : 9782889715053
Author : Da’san Mahmoud Mousa Jaradat,Munir Al-Zeer,Balakumar Chandrasekaran,Saeid Abu-Romman
Publisher : Frontiers Media SA
Page : 419 pages
File Size : 52,9 Mb
Release : 2021-11-16
Category : Science
ISBN : 9782889716470
Topic Editor Dr. Balakumar Chandrasekaran holds patents relating to N-substituted isatin hydrazones as antimycobacterial and antimicrobial agents, and Pharmaceutical Compounds. Topic Editor Dr. Munir Al-Zeer holds a patent relating to Method for the Preparation of an Influenza Virus. All other Topic Editors declare no competing interests.
Author : Hifzur Siddique,Maryam Sarwat
Publisher : Academic Press
Page : 720 pages
File Size : 48,9 Mb
Release : 2022-02-14
Category : Medical
ISBN : 9780323906999
Herbal Medicines: A Boon for Healthy Human Life provides a comprehensive overview of the role of herbal medicines for treating a broad variety of human diseases, from neurological disorders to cancer and major disorders such as infectious diseases, metabolic disorders, and more. Each chapter summarizes the current state and future direction of the use of herbal medicines against multiple diseases from a translational point-of-view, making this reference a valuable source of information for a large audience, including researchers and healthcare providers interested in the field of herbal remedies. Discusses essential evidence-based information about herbal medicines Provides an update to new discoveries and recent advances on the use of herbal medicines to treat multiple human diseases Includes information on clinical studies and covers all major medicinal compounds, including alkaloids, glycosides, polyphenols and terpenes
Author : Andrzej Joachimiak
Publisher : Frontiers Media SA
Page : 206 pages
File Size : 40,8 Mb
Release : 2023-03-10
Category : Science
ISBN : 9782832517031
Author : Siddhartha Pati,Tanmay Sarkar,Dibyajit Lahiri
Publisher : Elsevier
Page : 706 pages
File Size : 51,5 Mb
Release : 2023-04-26
Category : Science
ISBN : 9780443158087
Phytochemicals have been present in human diet and life since the birth of mankind, including the consuming of plant foods and the application of herbal treatments. This coevolutionary interaction of plants and people has resulted in humans' reliance on food and medicinal plants as sources of macronutrients, micronutrients, and bioactive phytochemicals. Phytochemicals can be used as adjuvant agents and sensitizers in traditional antibiotic and anticancer therapy, reducing the potential of selecting resistant microbial strains and cancer cells. Recent Frontiers of Phytochemicals addresses the many processes of potential phytochemical evaluation of known sources, with a focus on phytochemical and pharmacological evaluations, and computational research into the structures and pharmacological mechanisms of natural products and their applications in medicine, food and biotech. Novel extraction, characterization, and application method for phytochemicals in food, pharmacology, and biotechnology Colour illustrations and extensive tables with state-of-art information Covers potential sources of phytochemicals, their extraction and characterization techniques
Author : Douglas D. Richman,Richard J. Whitley,Frederick G. Hayden
Publisher : John Wiley & Sons
Page : 1489 pages
File Size : 41,9 Mb
Release : 2020-07-10
Category : Medical
ISBN : 9781555819439
The essential reference of clinical virology Virology is one of the most dynamic and rapidly changing fields of clinical medicine. For example, sequencing techniques from human specimens have identified numerous new members of several virus families, including new polyomaviruses, orthomyxoviruses, and bunyaviruses. Clinical Virology, Fourth Edition, has been extensively revised and updated to incorporate the latest developments and relevant research. Chapters written by internationally recognized experts cover novel viruses, pathogenesis, epidemiology, diagnosis, treatment, and prevention, organized into two major sections: Section 1 provides information regarding broad topics in virology, including immune responses, vaccinology, laboratory diagnosis, principles of antiviral therapy, and detailed considerations of important organ system manifestations and syndromes caused by viral infections. Section 2 provides overviews of specific etiologic agents and discusses their biology, epidemiology, pathogenesis of disease causation, clinical manifestations, laboratory diagnosis, and management. Clinical Virology provides the critical information scientists and health care professionals require about all aspects of this rapidly evolving field.
Author : Dmitri Fedorov,Kazuo Kitaura
Publisher : CRC Press
Page : 304 pages
File Size : 45,5 Mb
Release : 2009-05-14
Category : Science
ISBN : 9781420078497
Answering the need to facilitate quantum-chemical calculations of systems with thousands of atoms, Kazuo Kitaura and his coworkers developed the Fragment Molecular Orbital (FMO) method in 1999. Today, the FMO method can be applied to the study of whole proteins and protein-ligand interactions, and is extremely effective in calculating the propertie
Author : Tatsuya Sugawara,Takashi Maoka
Publisher : MDPI
Page : 744 pages
File Size : 46,5 Mb
Release : 2021-01-22
Category : Science
ISBN : 9783039431908
Carotenoids represent a large group of isoprenoid structures with many different structural characteristics and biological activities. They are the most important of the naturally occurring pigments and are responsible for the various colors of different fruits, vegetables, and plant parts. Marine carotenoids and their unique structures are responsible for the color of many fish, shellfish, and algae. However, while there have been many papers and reviews on carotenoids of terrestrial origin, there has been relatively little research conducted on the impact of marine carotenoids on human health. Recent research efforts have revealed that marine carotenoids have strong biological activity affecting human health and are candidates for nutraceuticals. This Topical Collection of Marine Drugs is dedicated to marine carotenoids, and will focus on the benefits of carotenoids for human beings. For a better understanding of the physiological effects of marine carotenoids, this collection should include the most recent developments in the presence, analysis, chemistry, and biochemistry of marine carotenoids.
Author : Rajeshwar P. Sinha,h.c. Donat-P. Häder
Publisher : Academic Press
Page : 502 pages
File Size : 51,5 Mb
Release : 2020-10-06
Category : Science
ISBN : 9780128206591
Natural Bioactive Compounds: Technological Advancements deals with the latest breakthroughs in the field of screening, characterization and novel applications of natural bioactive compounds from diverse group of organisms ranging from bacteria, viruses, cyanobacteria, algae, fungi, bryophytes, higher plants, sponges, corals and fishes. Written by some of the most reputed scientists in the field, this book introduces the reader to strategies and methods in the search for bioactive natural products. It is an essential read for researchers and students interested in bioactive natural products, their biological and pharmacological properties, their possible use as chemopreventive or chemotherapeutic agents, and other future potential applications. Explores natural sources of bioactive compounds, including cyanobacteria, bacteria, viruses, fungi and higher plants Discusses the potential applications of biological products, such as their use in medicine (antibiotics, cancer research, immunology), as food additives, supplements and technological substances Analyzes the contributions of emerging or developing technologies for the study of bioactive natural compounds (characterization and purification)
Author : Alexander Heifetz
Publisher : Humana
Page : 360 pages
File Size : 45,5 Mb
Release : 2021-02-18
Category : Medical
ISBN : 1071602845
This volume looks at applications of quantum mechanical (QM) methods in drug discovery. The chapters in this book describe how QM approaches can be applied to address key drug discovery issues, such as characterizing protein-water-ligand and protein-protein interactions, providing estimates of binding affinities, determining ligand energies and bioactive conformations, refinement of molecular geometries, scoring docked protein–ligand poses, describing molecular similarity, structure–activity-relationship (SAR) analysis, and ADMET prediction. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary software and tools, step-by-step, readily reproducible modeling protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and unique, Quantum Mechanics in Drug Discovery is a valuable resource for structural and molecular biologists, computational and medicinal chemists, pharmacologists, and drug designers.
Author : Rafael Trindade Maia,Rômulo Maciel de Moraes Filho,Magnólia De Araújo Campos
Publisher : BoD – Books on Demand
Page : 147 pages
File Size : 50,9 Mb
Release : 2021-03-10
Category : Science
ISBN : 9781839628054
Homology modeling is an extremely useful and versatile technique that is gaining more and more space and demand in research in computational and theoretical biology. This book, “Homology Molecular Modeling - Perspectives and Applications”, brings together unpublished chapters on this technique. In this book, 7 chapters are intimately related to the theme of molecular modeling, carefully selected and edited for academic and scientific readers. It is an indispensable read for anyone interested in the areas of bioinformatics and computational biology. Divided into 4 sections, the reader will have a didactic and comprehensive view of the theme, with updated and relevant concepts on the subject. This book was organized from researchers to researchers with the aim of spreading the fascinating area of molecular modeling by homology.
Author : Anne E. Osbourn,Virginia Lanzotti
Publisher : Springer Science & Business Media
Page : 588 pages
File Size : 48,6 Mb
Release : 2009-07-07
Category : Science
ISBN : 9780387854984
Plants produce a huge array of natural products (secondary metabolites). These compounds have important ecological functions, providing protection against attack by herbivores and microbes and serving as attractants for pollinators and seed-dispersing agents. They may also contribute to competition and invasiveness by suppressing the growth of neighboring plant species (a phenomenon known as allelopathy). Humans exploit natural products as sources of drugs, flavoring agents, fragrances and for a wide range of other applications. Rapid progress has been made in recent years in understanding natural product synthesis, regulation and function and the evolution of metabolic diversity. It is timely to bring this information together with contemporary advances in chemistry, plant biology, ecology, agronomy and human health to provide a comprehensive guide to plant-derived natural products. Plant-derived natural products: synthesis, function and application provides an informative and accessible overview of the different facets of the field, ranging from an introduction to the different classes of natural products through developments in natural product chemistry and biology to ecological interactions and the significance of plant-derived natural products for humans. In the final section of the book a series of chapters on new trends covers metabolic engineering, genome-wide approaches, the metabolic consequences of genetic modification, developments in traditional medicines and nutraceuticals, natural products as leads for drug discovery and novel non-food crops.
Author : Vishwanath Gaitonde,Partha Karmakar,Ashit Trivedi
Publisher : BoD – Books on Demand
Page : 166 pages
File Size : 44,6 Mb
Release : 2020-03-11
Category : Medical
ISBN : 9781789239751
The process of drug discovery and development is a complex multistage logistics project spanned over 10-15 years with an average budget exceeding 1 billion USD. Starting with target identification and synthesizing anywhere between 10k to 15k synthetic compounds to potentially obtain the final drug that reaches the market involves a complicated maze with multiple inter- and intra-operative fields. Topics described in this book emphasize the progresses in computational applications, pharmacokinetics advances, and molecular modeling developments. In addition the book also contains special topics describing target deorphaning in Mycobacterium tuberculosis, therapy treatment of some rare diseases, and developments in the pediatric drug discovery process.