Intercellular Communication Through Gap Junctions

Author : Y. Kanno,K. Kataoka,Y. Shiba,Y. Shibata,T. Shimazu
Publisher : Newnes
Page : 474 pages
File Size : 45,6 Mb
Release : 1995-02-09
Category : Science
ISBN : 9780444599520

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Intercellular Communication through Gap Junctions by Y. Kanno,K. Kataoka,Y. Shiba,Y. Shibata,T. Shimazu Pdf

Research on intercellular communication through gap junctions has continued to expand, and the meeting on which this book is based brought together many scientists from many different countries and disciplines. In line with the objective of the meeting, this volume focuses on the biological meaning of intercellular communication through gap junctions in various organs. The most recent up-to-date findings have been included in this extensive volume, valuable to all those interested in this rapidly expanding field.

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 48,6 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : František Baluška,Dieter Volkmann,Peter W. Barlow
Publisher : Springer Science & Business Media
Page : 331 pages
File Size : 46,5 Mb
Release : 2006-08-28
Category : Science
ISBN : 9780387360584

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Cell-Cell Channels by František Baluška,Dieter Volkmann,Peter W. Barlow Pdf

This book covers cell-cell channels at all levels of biological organization. The purpose of this book is to document that cells are not physically separated and fully autonomous units of biological life as stated by the currently valid Cell Theory. If not the cell then some lower level unit must fulfill this role. The book deals also with the identity of this elusive unit of biological life.

Author : Gail Cardew
Publisher : John Wiley & Sons
Page : 296 pages
File Size : 41,5 Mb
Release : 2008-04-30
Category : Science
ISBN : 9780470515594

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Gap Junction-Mediated Intercellular Signalling in Health and Disease by Gail Cardew Pdf

Gap junctions are key elements in communication between cells in multicellular organisms. It is clear that their activity is essential for normal embryonic development and normal function in adult organs, although the individual roles of the proteins that form the channels (connexins) are not yet fully understood. The last few years have seen considerable progress in this field and exciting new issues concerning gap junctional intercellular communication are being raised. Perturbed gap junction activity is beginning to be linked to certain pathologies, e.g. mutations in the major connexin of the heart have been found in human patients suffering from visceroatrial heterotaxia syndrome and mutations in the gene encoding another connexin have been found in patients with Charcot-Marie-Tooth disease. This book is the first to highlight the recent progress in understanding gap junction structure and to discuss the specific roles of individual connexins. It features contributions from an interdisciplinary group of experts who review the role of gap junctions in the heart, the retina and lens, the auditory system, the reproductive system, and in cell proliferation and cancer. The book will appeal to people interested in cell and molecular biology, embryonic development, neurobiology, cardiology, gynaecology and oncology.

Author : Rudolf Werner
Publisher : IOS Press
Page : 412 pages
File Size : 51,6 Mb
Release : 1998
Category : Gap junctions (Cell biology)
ISBN : 9051993749

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Gap Junctions by Rudolf Werner Pdf

This monograph contains research articles from the leading laboratories around the world on gap junctions, the intercellular channels that allow communication between neighbouring cells. It describes the latest results in gap junctions research, the structural and functional characterization of cell-cell channels, the assembly and degradation of gap junctions, the expression and function of gap junctions in different tissues, knockout studies of gap junction genes, the regulation of connexin gene expression, and the functions of gap junctions in development and cancer. Any laboratory interested in intercellular communications and gap junction research will find this monograph an indispensable source of information and reference.

Author : E.L. Hertzberg,Elliot L. Hertzberg
Publisher : Elsevier
Page : 432 pages
File Size : 52,8 Mb
Release : 2000-01-10
Category : Science
ISBN : 0762305991

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Gap Junctions by E.L. Hertzberg,Elliot L. Hertzberg Pdf

The objective in editing this volume was twofold: to provide a reasoned overview of the field as well as to furnish one that provided this overview within the context of the intellectual boundaries of those who initially attempted to define the purview of gap junction research. The latter objective has been realized by selecting the topics for review in this volume. The former objective was achieved by securing the cooperation of leaders in their fields as chapter co-authors.

Author : Anonim
Publisher : Academic Press
Page : 648 pages
File Size : 51,8 Mb
Release : 1999-12-22
Category : Science
ISBN : 0080585205

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Gap Junctions: Molecular Basis of Cell Communication in Health and Disease by Anonim Pdf

Since the first gap junction protein (connexin) was cloned over a decade ago, more than a dozen connexin genes have been cloned. Consequently, a wealth of information on the molecular basis of gap junctional communication has been accumulated. This book pays tribute to this exciting era in the history of cell communication research by documenting the great strides made in this field as a result of the merging of biophysics and molecular biology, two of the most powerful approaches to studying the molecular basis of membrane channel behavior. Twenty-eight comprehensive chapters, authored by internationally recognized leaders in the field, discuss the biophysical, physiological, and molecular characteristics of cell-to-cell communication via gap junctions. Key aspects of molecular structure, formation, gating, conductance, and permeability of vertebrate and invertebrate gap junction channels are highlighted. In addition, a number of chapters focus on recent discoveries that implicate connexin mutations and alterations of gap junctional communication in the pathogenesis of several diseases, including the X-linked Charcot Marie Tooth demyelinating disease, some forms of inherited sensorineural deafness, malignant transformation, cardiac malformations and arrhythmia, eye lens cataract, and Chagas' disease.

Author : Elke Winterhager
Publisher : Springer Science & Business Media
Page : 312 pages
File Size : 54,6 Mb
Release : 2005-07-19
Category : Health & Fitness
ISBN : 3540261567

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Gap Junctions in Development and Disease by Elke Winterhager Pdf

Communication between cells via intercellular channels – gap junctions – appears essential to certain developmental processes and appropriate organ function. Gap Junctions in Development and Disease aims to describe the molecular events underlying impaired development and disease. Beginning with a comprehensive review of various mouse and human genes encoding the channel-forming connexins, later chapters describe several connexin mutations associated with human diseases such as hereditary deafness and female infertility. Erroneous signaling mediated by the interaction of mutant connexins with other proteins, thought to be responsible for dysfunction of organs such as heart, muscle, brain, skin, lens, placenta, and endocrine tissue in both mice and men, is also addressed. Although the question of why some mutations in gap-junction proteins lead to specific phenotypes remains to be answered, the reviews in this book provide an intriguing insight into the future direction of this research field.

Author : J.E. Hall,Guido Zampighi,R.M. Davis
Publisher : Elsevier
Page : 356 pages
File Size : 41,9 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780444599841

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Gap Junctions by J.E. Hall,Guido Zampighi,R.M. Davis Pdf

Gap junctions are present in nearly all tissues, regardless of their embronic origin and have long been of great interest to scientists from many different disciplines. The international meeting on which this book is based brought together 157 scientists from 12 countries and almost as many scientific disciplines. The papers presented at the meeting were reviewed and updated prior to publication in this book. The seven parts of the book progress from general topics to the more specific ones (role of gap junctions in various tissues, regulation and biochemistry, and cancer).

Author : A.W. Robards,W.J. Lucas,John D. Pitts,H.J. Jongsma,D.C. Spray
Publisher : Springer Science & Business Media
Page : 282 pages
File Size : 47,9 Mb
Release : 2013-06-29
Category : Science
ISBN : 9783642839719

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Parallels in Cell to Cell Junctions in Plants and Animals by A.W. Robards,W.J. Lucas,John D. Pitts,H.J. Jongsma,D.C. Spray Pdf

Intracellular junctions provide routes for direct cell-to-cell signalling in both plants and animals. The present volume treats the parallels and differences between such junctions in animals and plants and discusses the most recent methods of examining the physiological functions and regulation of intracellular communication. Strong evidence of both molecular as well as functional simi§ larities between plasmodesmata and gap junctions is increasing. Even more interesting is the discovery that animal gap junction proteins cross-react immunologically with some proteins in plant cells. Thus the molecular construction and function of these crucially important ultrastructural cell components is now open to a concerted research effort to understand how cells, both plant and animal, facilitate and regulate intercellular transport.

Author : James Keener,James Sneyd
Publisher : Springer Science & Business Media
Page : 1067 pages
File Size : 40,7 Mb
Release : 2010-06-04
Category : Mathematics
ISBN : 9780387758473

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Mathematical Physiology by James Keener,James Sneyd Pdf

Divided into two volumes, the book begins with a pedagogical presentation of some of the basic theory, with chapters on biochemical reactions, diffusion, excitability, wave propagation and cellular homeostasis. The second, more extensive part discusses particular physiological systems, with chapters on calcium dynamics, bursting oscillations and secretion, cardiac cells, muscles, intercellular communication, the circulatory system, the immune system, wound healing, the respiratory system, the visual system, hormone physiology, renal physiology, digestion, the visual system and hearing. New chapters on Calcium Dynamics, Neuroendocrine Cells and Regulation of Cell Function have been included. Reviews from first edition: Keener and Sneyd's Mathematical Physiology is the first comprehensive text of its kind that deals exclusively with the interplay between mathematics and physiology. Writing a book like this is an audacious act! -Society of Mathematical Biology Keener and Sneyd's is unique in that it attempts to present one of the most important subfields of biology and medicine, physiology, in terms of mathematical "language", rather than organizing materials around mathematical methodology. -SIAM review

Author : David C. Spray,Rolf Dermietzel
Publisher : Springer Science & Business Media
Page : 321 pages
File Size : 40,7 Mb
Release : 2013-06-29
Category : Medical
ISBN : 9783662219355

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Gap Junctions in the Nervous System by David C. Spray,Rolf Dermietzel Pdf

This book deals with the types of gap junction proteins (connexins) and their distribution within the nervous system, the physiological properties of channels formed of each connexin, and the role of gap junction channels in functions of normal and pathological brain and peripheral nerve. Although glial tissue is emphasized, additional groups of chapters deal with neurons in the central nervous system and with the retina.

Author : J. Bereiter-Hahn,A.G. Matoltsy,K.S. Richards
Publisher : Springer Science & Business Media
Page : 858 pages
File Size : 49,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642515934

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Biology of the Integument by J. Bereiter-Hahn,A.G. Matoltsy,K.S. Richards Pdf

The integument plays an important role in the survival of meta zoans by separating and protecting them from a hostile environ ment. Its function ranges from protection against injury and in fection; partlcipation in the regulation of body temperature and water balance, to respiratory activity, monitoring of the environ ment and production of signals related to behaviour. All these result from specific structural, biochemical and physiological properties of intra-and extracellular components of the integu ment. Thus its characterization can be best accomplished by a multidisciplinary approach with authors specialized in different fields of science. This multi-author book, in two volumes, provides an up-to date survey of the literature. The first volume deals with the integument of invertebrates, the second with that of vertebrates, both organized primarily on a phylum basis. As the level of knowledge on the integument of phyla differs considerably, the information provided is correspondingly either limited or con densed. For some of the smaller groups of invertebrates little information is available, as often only a few electron micrographs are to be found in the literature; on the other hand, from the large body of knowledge existing for vertebrates, particularly for mammals, no complete overview can be provided, but publica tions giving access to further information have been reviewed critically.

Author : Walmor C. De Mello
Publisher : Springer Science & Business Media
Page : 383 pages
File Size : 42,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461319177

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Cell-to-Cell Communication by Walmor C. De Mello Pdf

Author : Ekrem Dere
Publisher : Academic Press
Page : 318 pages
File Size : 49,9 Mb
Release : 2012-08-30
Category : Medical
ISBN : 9780124159013

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Gap Junctions in the Brain by Ekrem Dere Pdf

In addition to chemical links across synapses, neurons can also form direct connections via electrical gap junctions. These channels play a key role in brain development and intercellular communication. Dere (pathophysiology of cerebral aging, U. Pierre et Marie Curie, Paris; AP-HP Hôpital Charles Foix, Centre de Recherche et Développement, Ivry-sur-Seine, France) introduces types of gap junctions, their structural aspects, expression patterns of connexins (transmembrane proteins), and gap junction-related diseases due to mutations in connexin genes. International researchers working in this emerging field discuss specific connexin genes and their mechanisms of action and function in the developing neocortx, behavior, and neurological and neuropsychiatric diseases. The text includes color and b&w illustrations including schematic representations and models. Academic Press is an imprint of Elsevier. Annotation ©2013 Book News, Inc., Portland, OR (booknews.com).