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Author : Walter George Bradley
Publisher : Unknown
Page : 1672 pages
File Size : 47,5 Mb
Release : 2004
Category : Medical
ISBN : 0750674695
New edition, completely rewritten, with new chapters on endovascular surgery and mitochrondrial and ion channel disorders.
Author : National Academies of Sciences Engineering and Medicine,Division of Behavioral and Social Sciences and Education,Board on Behavioral Cognitive and Sensory Sciences,Committee on the Decadal Survey of Behavioral and Social Science Research on Alzheimer's Disease and Alzheimer's Disease-Related Dementias
Publisher : Unknown
Page : 128 pages
File Size : 50,8 Mb
Release : 2022-04-26
Category : Electronic
ISBN : 0309495032
As the largest generation in U.S. history - the population born in the two decades immediately following World War II - enters the age of risk for cognitive impairment, growing numbers of people will experience dementia (including Alzheimer's disease and related dementias). By one estimate, nearly 14 million people in the United States will be living with dementia by 2060. Like other hardships, the experience of living with dementia can bring unexpected moments of intimacy, growth, and compassion, but these diseases also affect people's capacity to work and carry out other activities and alter their relationships with loved ones, friends, and coworkers. Those who live with and care for individuals experiencing these diseases face challenges that include physical and emotional stress, difficult changes and losses in their relationships with life partners, loss of income, and interrupted connections to other activities and friends. From a societal perspective, these diseases place substantial demands on communities and on the institutions and government entities that support people living with dementia and their families, including the health care system, the providers of direct care, and others. Nevertheless, research in the social and behavioral sciences points to possibilities for preventing or slowing the development of dementia and for substantially reducing its social and economic impacts. At the request of the National Institute on Aging of the U.S. Department of Health and Human Services, Reducing the Impact of Dementia in America assesses the contributions of research in the social and behavioral sciences and identifies a research agenda for the coming decade. This report offers a blueprint for the next decade of behavioral and social science research to reduce the negative impact of dementia for America's diverse population. Reducing the Impact of Dementia in America calls for research that addresses the causes and solutions for disparities in both developing dementia and receiving adequate treatment and support. It calls for research that sets goals meaningful not just for scientists but for people living with dementia and those who support them as well. By 2030, an estimated 8.5 million Americans will have Alzheimer's disease and many more will have other forms of dementia. Through identifying priorities social and behavioral science research and recommending ways in which they can be pursued in a coordinated fashion, Reducing the Impact of Dementia in America will help produce research that improves the lives of all those affected by dementia.
Author : Uday Kishore
Publisher : BoD – Books on Demand
Page : 642 pages
File Size : 50,5 Mb
Release : 2013-05-15
Category : Medical
ISBN : 9789535110880
This book highlights the pathophysiological complexities of the mechanisms and factors that are likely to be involved in a range of neuroinflammatory and neurodegenerative diseases including Alzheimer's disease, other Dementia, Parkinson Diseases and Multiple Sclerosis. The spectrum of diverse factors involved in neurodegeneration, such as protein aggregation, oxidative stress, caspases and secretase, regulators, cholesterol, zinc, microglia, astrocytes, oligodendrocytes, etc, have been discussed in the context of disease progression. In addition, novel approaches to therapeutic interventions have also been presented. It is hoped that students, scientists and clinicians shall find this very informative book immensely useful and thought-provoking.
Author : Ruth M. Tappen
Publisher : Health Professions Press
Page : 266 pages
File Size : 47,7 Mb
Release : 1997
Category : Alzheimer's disease
ISBN : UOM:39015041763064
This book is written for professionals who find themselves responsible for the planning, administrations, or provision of services for the increasing number of older people with Alzheimer's disease and the related dementing diseases. It provides a background for understanding the disease itself and suggests a wide range of potentially effective interventions for people in the early, middle, and late stages of Alzheimer's disease. Most important, this information is provided within a framework of care and concern for the person with the disease and an emphasis on honoring the person's rights to respect, privacy, and preservation of dignity. This compregensive, easy-to-read volume distills the critical information you need from current research and translates it into effective methods of care that can improve individual's functional abilities and well-being from the early to the end stages of the disease.
Author : Magisetty Obulesu
Publisher : Academic Press
Page : 80 pages
File Size : 48,6 Mb
Release : 2019-01-20
Category : Medical
ISBN : 9780128167397
Alzheimer’s Disease Theranostics discusses the latest information on recent theranostic avenues for both the diagnosis and treatment of Alzheimer’s patients. It presents the pros and cons of the probable mechanistic role of nanoparticles in crossing the blood-brain barrier and improving disease symptoms. Finally, it highlights the merits of existing maneuvers and suggests perspectives to aid in future developments. Despite the difficulty of drug delivery to the brain, there are some nanoparticulate platforms demonstrating promise in treating neurodegenerative disorders such as Alzheimer’s disease. Manifold theranostic maneuvers include antioxidants, natural bioactive compounds, gene therapy, and nanotechnological approaches, all of which are discussed in this important work. Examines various theranostic applications for the diagnosis and treatment of Alzheimer’s disease Features a comprehensive overview of nanoparticle therapeutics in the area and use of antioxidants Assesses the common challenges and lessons learned from blood-brain barrier challenges, viral vector approaches and mitochondria-targeted therapeutics
Author : National Academies of Sciences Engineering and Medicine,Health and Medicine Division,Board on Health Care Services,Board on Health Sciences Policy,Committee on Care Interventions for Individuals with Dementia and Their Caregivers
Publisher : Unknown
Page : 128 pages
File Size : 48,8 Mb
Release : 2021-11-23
Category : Electronic
ISBN : 0309154294
Author : Dale Bredesen
Publisher : Penguin
Page : 320 pages
File Size : 41,5 Mb
Release : 2017-08-22
Category : Health & Fitness
ISBN : 9780735216228
The instant New York Times and Wall Street Journal bestseller A groundbreaking plan to prevent and reverse Alzheimer’s Disease that fundamentally changes how we understand cognitive decline. Everyone knows someone who has survived cancer, but until now no one knows anyone who has survived Alzheimer's Disease. In this paradigm shifting book, Dale Bredesen, MD, offers real hope to anyone looking to prevent and even reverse Alzheimer's Disease and cognitive decline. Revealing that AD is not one condition, as it is currently treated, but three, The End of Alzheimer’s outlines 36 metabolic factors (micronutrients, hormone levels, sleep) that can trigger "downsizing" in the brain. The protocol shows us how to rebalance these factors using lifestyle modifications like taking B12, eliminating gluten, or improving oral hygiene. The results are impressive. Of the first ten patients on the protocol, nine displayed significant improvement with 3-6 months; since then the protocol has yielded similar results with hundreds more. Now, The End of Alzheimer’s brings new hope to a broad audience of patients, caregivers, physicians, and treatment centers with a fascinating look inside the science and a complete step-by-step plan that fundamentally changes how we treat and even think about AD.
Author : Jeffrey Cummings,Jefferson Kinney,Howard Fillit
Publisher : Cambridge University Press
Page : 575 pages
File Size : 43,6 Mb
Release : 2022-03-31
Category : Business & Economics
ISBN : 9781108838665
Provides a definitive overview of the complex ecosystem facilitating Alzheimer's Disease drug research and development. Demonstrates a drug's journey from in the lab, clinical trial testing, regulatory review, and marketing by pharmaceutical companies. Details the use of artificial intelligence, clinical trial management, and financing models.
Author : American Psychiatric Association
Publisher : American Psychiatric Pub
Page : 220 pages
File Size : 54,6 Mb
Release : 2016
Category : Antipsychotic drugs
ISBN : 9780890426777
The guideline offers clear, concise, and actionable recommendation statements to help clinicians to incorporate recommendations into clinical practice, with the goal of improving quality of care. Each recommendation is given a rating that reflects the level of confidence that potential benefits of an intervention outweigh potential harms.
Author : Ann Louise Barrick PhD,Joanne Rader RN, MN, PMHNP,Beverly Hoeffer DNSc, RN, FAAN,Philip D. Sloane MD, MPH,Stacey Biddle COTA/L
Publisher : Springer Publishing Company
Page : 180 pages
File Size : 55,8 Mb
Release : 2008-03-10
Category : Medical
ISBN : 0826115071
2008 AJN Book of the Year Winner! Like its popular predecessor, the new edition of Bathing Without a Battle presents an individualized, problem-solving approach to bathing and personal care of individuals with dementia. On the basis of extensive original research and clinical experience, the editors have developed strategies and techniques that work in both institution and home settings. Their approach is also appropriate for caregiving activities other than bathing, such as morning and evening care, and for frail elders not suffering from dementia. For this second edition, the authors have included historical material on bathing and substantially updated the section on special concerns, including: Pain Skin care Determining the appropriate level of assistance Transfers The environment An enhanced final section addresses ways to support caregivers by increasing their understanding of the care recipient's needs and their knowledge of interventions to improve care and comfort. It also emphasizes self-care and system-level changes to promote person-directed care. Several chapters include specific insights and wisdom from direct caregivers.
Author : Enid Light,Barry Lebowitz
Publisher : Taylor & Francis
Page : 504 pages
File Size : 48,8 Mb
Release : 1990
Category : Medical
ISBN : 1560321377
Author : Adeboye Adejare
Publisher : Academic Press
Page : 316 pages
File Size : 55,7 Mb
Release : 2016-09-20
Category : Medical
ISBN : 9780128028117
Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimer’s Disease examines the drug discovery process for neurodegenerative diseases by focusing specifically on Alzheimer’s Disease and illustrating the paradigm necessary to ensure future research and treatment success. The book explores diagnosis, epidemiology, drug discovery strategies, current therapeutics, and much more to provide a holistic approach to the discovery, development, and treatment of Alzheimer’s Disease. Through its coverage of the latest research in targeted drug design, preclinical studies, and mouse and rat models, the book is a must-have resource for all pharmaceutical scientists, pharmacologists, neuroscientists, and clinical researchers working in this area. It illustrates why these drugs tend to fail at the clinical stage, and examines Alzheimer’s Disease within the overall context of improving the drug discovery process for the treatment of other neurodegenerative disorders. Provides a compilation of chemical considerations required in drug discovery for the treatment of neurodegenerative disorders Examines different classes of compounds currently being used in discovery and development stages Explores in vitro and in vivo models with respect to their ability to translate these models to human conditions Distills the most significant information across multiple areas of Alzheimer’s disease research to provide a single, comprehensive, and balanced resource
Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Family Caregiving for Older Adults
Publisher : National Academies Press
Page : 367 pages
File Size : 49,6 Mb
Release : 2016-11-08
Category : Medical
ISBN : 9780309448093
Family caregiving affects millions of Americans every day, in all walks of life. At least 17.7 million individuals in the United States are caregivers of an older adult with a health or functional limitation. The nation's family caregivers provide the lion's share of long-term care for our older adult population. They are also central to older adults' access to and receipt of health care and community-based social services. Yet the need to recognize and support caregivers is among the least appreciated challenges facing the aging U.S. population. Families Caring for an Aging America examines the prevalence and nature of family caregiving of older adults and the available evidence on the effectiveness of programs, supports, and other interventions designed to support family caregivers. This report also assesses and recommends policies to address the needs of family caregivers and to minimize the barriers that they encounter in trying to meet the needs of older adults.
Author : Institute of Medicine,Committee on Prevention of Mental Disorders
Publisher : National Academies Press
Page : 636 pages
File Size : 52,9 Mb
Release : 1994-01-01
Category : Medical
ISBN : 9780309049399
The understanding of how to reduce risk factors for mental disorders has expanded remarkably as a result of recent scientific advances. This study, mandated by Congress, reviews those advances in the context of current research and provides a targeted definition of prevention and a conceptual framework that emphasizes risk reduction. Highlighting opportunities for and barriers to interventions, the book draws on successful models for the prevention of cardiovascular disease, injuries, and smoking. In addition, it reviews the risk factors associated with Alzheimer's disease, schizophrenia, alcohol abuse and dependence, depressive disorders, and conduct disorders and evaluates current illustrative prevention programs. The models and examination provide a framework for the design, application, and evaluation of interventions intended to prevent mental disorders and the transfer of knowledge about prevention from research to clinical practice. The book presents a focused research agenda, with recommendations on how to develop effective intervention programs, create a cadre of prevention researchers, and improve coordination among federal agencies.
Author : Carole B. Cox, PhD
Publisher : Springer Publishing Company
Page : 456 pages
File Size : 47,9 Mb
Release : 2007-04-15
Category : Social Science
ISBN : 0826101089
"Practical coverage of driving, day care, support groups, and respite is particularly welcome. This is a good book to have available, not just for social work faculty and students, but also for those in the health sciences, psychology, and sociology. It will be a useful resource for professionals coping with the increasing problems for family and community that an aging population and the epidemic of Alzheimer's disease bring with them....Recommended. Lower-level undergraduate through professionals/practitioners."--Choice Beyond the immediate and devastating effects dementia can have on individuals and their quality of life are the strains that are placed on the families, caregivers, and communities that support them. Social workers are in a unique position to address all these issues at the same time that they provide care for individuals with dementia. To facilitate the entrance of social workers into this area of care, Carol B. Cox has edited a volume of expert articles on the biological, psychological, and social aspects of dementia. . Readers will learn the latest assessment instruments, as well as how to distinguish between Alzheimer's and non-Alzheimer's dementias. Intervention strategies for every stage of dementia are presented. The effects of culture and diversity on the treatment of persons with dementia are examined, including examples of successful programs from several countries. The benefits and drawbacks of adult day services, community care, and residential care are discussed. Finally, a discussion of the legal, financial, and psychological stresses faced by caregivers of those with dementia rounds out this much needed text.