Introduction To Enzymology

Author : Alan H. Mehler
Publisher : Elsevier
Page : 434 pages
File Size : 41,8 Mb
Release : 2014-05-12
Category : Science
ISBN : 9781483258478

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Introduction to Enzymology by Alan H. Mehler Pdf

Introduction to Enzymology focuses on the processes, methodologies, reactions, and approaches involved in enzyme chemistry. The book first offers information on the hydrolysis of peptides and proteins and fermentation and oxidation of major metabolic fuels. Discussions focus on oxidation of fatty acids, alternative pathways of carbohydrate metabolism, Krebs citric acid cycle, free energy and the concept of bond energy, pyruvate oxidation and acetyl coenzyme A formation, and glycolysis. The text then elaborates on the transfer of oxygen, hydrogen, and electrons and sugars and sugar derivatives. The publication takes a look at polynucleotides and their components, amino acids, and acids and acid derivatives. Topics include carbonic anhydrase, mechanism of action of pyridoxal phosphate enzymes, aromatic ring biosynthesis and metabolism of phenylalanine and tyrosine, metabolism of sulfur-containing amino acids, and oxidation of amino acids. The book is a valuable reference for chemists and researchers interested in enzymology.

Author : Paul Engel
Publisher : Oxford University Press
Page : 193 pages
File Size : 49,5 Mb
Release : 2020-11-26
Category : Science
ISBN : 9780192558817

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Enzymes: A Very Short Introduction by Paul Engel Pdf

Enzymes are the astonishing, tiny molecular machines that make life possible. Each one of these small proteins speeds up a single chemical reaction inside a living organism many millionfold. Working together, teams of enzymes carry out all the processes that collectively we recognise as life, from making DNA to digesting food. This Very Short Introduction explains the why and the how of speeding up these reactions - catalysis - before going on to reveal how we have evolved these catalysts of such extraordinary power and exquisite selectivity. Paul Engel shows how X-ray crystallography has revealed the complex molecular shapes that allow enzymes to function at an extraordinarily sophisticated level. He also examines medical aspects of enzymes, both in the way faulty enzymes cause disease and in the way enzymes can be used for diagnosis and therapy. Finally, he looks at the many varied ways in which individual enzymes, taken out of their biological context, are used nowadays as tools - in washing powders, food production, waste treatment, and chemical synthesis. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Author : Robert A. Copeland
Publisher : John Wiley & Sons
Page : 416 pages
File Size : 44,5 Mb
Release : 2004-04-07
Category : Science
ISBN : 9780471461852

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Enzymes by Robert A. Copeland Pdf

Fully updated and expanded-a solid foundation for understandingexperimental enzymology. This practical, up-to-date survey is designed for a broadspectrum of biological and chemical scientists who are beginning todelve into modern enzymology. Enzymes, Second Editionexplains the structural complexities of proteins and enzymes andthe mechanisms by which enzymes perform their catalytic functions.The book provides illustrative examples from the contemporaryliterature to guide the reader through concepts and data analysisprocedures. Clear, well-written descriptions simplify the complexmathematical treatment of enzyme kinetic data, and numerouscitations at the end of each chapter enable the reader to accessthe primary literature and more in-depth treatments of specifictopics. This Second Edition of Enzymes: A Practical Introductionto Structure, Mechanism, and Data Analysis features refinedand expanded coverage of many concepts, while retaining theintroductory nature of the book. Important new featuresinclude: A new chapter on protein-ligand binding equilibria Expanded coverage of chemical mechanisms in enzyme catalysisand experimental measurements of enzyme activity Updated and refined discussions of enzyme inhibitors andmultiple substrate reactions Coverage of current practical applications to the study ofenzymology Supplemented with appendices providing contact information forsuppliers of reagents and equipment for enzyme studies, as well asa survey of useful Internet sites and computer software forenzymatic data analysis, Enzymes, Second Edition isthe ultimate practical guide for scientists and students inbiochemical, pharmaceutical, biotechnical, medicinal, andagricultural/food-related research.

Author : T. D. H. Bugg
Publisher : John Wiley & Sons
Page : 310 pages
File Size : 42,8 Mb
Release : 2012-05-29
Category : Science
ISBN : 9781118348994

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Introduction to Enzyme and Coenzyme Chemistry by T. D. H. Bugg Pdf

Enzymes are giant macromolecules which catalyse biochemical reactions. They are remarkable in many ways. Their three-dimensional structures are highly complex, yet they are formed by spontaneous folding of a linear polypeptide chain. Their catalytic properties are far more impressive than synthetic catalysts which operate under more extreme conditions. Each enzyme catalyses a single chemical reaction on a particular chemical substrate with very high enantioselectivity and enantiospecificity at rates which approach “catalytic perfection”. Living cells are capable of carrying out a huge repertoire of enzyme-catalysed chemical reactions, some of which have little or no precedent in organic chemistry. The popular textbook Introduction to Enzyme and Coenzyme Chemistry has been thoroughly updated to include information on the most recent advances in our understanding of enzyme action, with additional recent examples from the literature used to illustrate key points. A major new feature is the inclusion of two-colour figures, and the addition of over 40 new figures of the active sites of enzymes discussed in the text, in order to illustrate the interplay between enzyme structure and function. This new edition provides a concise but comprehensive account from the perspective of organic chemistry, what enzymes are, how they work, and how they catalyse many of the major classes of enzymatic reactions, and will continue to prove invaluable to both undergraduate and postgraduate students of organic, bio-organic and medicinal chemistry, chemical biology, biochemistry and biotechnology.

Author : Robert Allen Copeland
Publisher : Wiley-VCH
Page : 336 pages
File Size : 43,8 Mb
Release : 1996
Category : Medical
ISBN : UOM:39015037847798

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Enzymes by Robert Allen Copeland Pdf

Supplemented with appendices providing contact information for suppliers of reagents and equipment for enzyme studies, as well as a survey of useful Internet sites and computer software for enzymatic data analysis, Enzymes, Second Edition is the ultimate practical guide for scientists and students in biochemical, pharmaceutical, biotechnical, medicinal, and agricultural/food-related research.

Author : T Palmer,P L Bonner
Publisher : Elsevier
Page : 434 pages
File Size : 46,6 Mb
Release : 2007-04-04
Category : Technology & Engineering
ISBN : 9780857099921

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Enzymes by T Palmer,P L Bonner Pdf

In recent years, there have been considerable developments in techniques for the investigation and utilisation of enzymes. With the assistance of a co-author, this popular student textbook has been updated to include techniques such as membrane chromatography, aqueous phase partitioning, engineering recombinant proteins for purification and due to the rapid advances in bioinformatics/proteomics, a discussion of the analysis of complex protein mixtures by 2D-electrophoresis and RPHPLC prior to sequencing by mass spectroscopy. Written with the student firmly in mind, no previous knowledge of biochemistry, and little of chemistry, is assumed. It is intended to provide an introduction to enzymology, and a balanced account of all the various theoretical and applied aspects of the subject which are likely to be included in a course. Provides an introduction to enzymology and a balanced account of the theoretical and applied aspects of the subject Discusses techniques such as membrane chromatography, aqueous phase partitioning and engineering recombinant proteins for purification Includes a discussion of the analysis of complex protein mixtures by 2D-electrophoresis and RPHPLC prior to sequencing by mass spectroscopy

Author : Karl-Erich Jaeger
Publisher : Springer Nature
Page : 467 pages
File Size : 41,5 Mb
Release : 2024-07-02
Category : Electronic
ISBN : 9783031429996

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Introduction to Enzyme Technology by Karl-Erich Jaeger Pdf

Author : N.S. Punekar
Publisher : Springer
Page : 562 pages
File Size : 44,7 Mb
Release : 2018-11-11
Category : Science
ISBN : 9789811307850

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ENZYMES: Catalysis, Kinetics and Mechanisms by N.S. Punekar Pdf

This enzymology textbook for graduate and advanced undergraduate students covers the syllabi of most universities where this subject is regularly taught. It focuses on the synchrony between the two broad mechanistic facets of enzymology: the chemical and the kinetic, and also highlights the synergy between enzyme structure and mechanism. Designed for self-study, it explains how to plan enzyme experiments and subsequently analyze the data collected. The book is divided into five major sections: 1] Introduction to enzymes, 2] Practical aspects, 3] Kinetic Mechanisms, 4] Chemical Mechanisms, and 5] Enzymology Frontiers. Individual concepts are treated as stand-alone chapters; readers can explore any single concept with minimal cross-referencing to the rest of the book. Further, complex approaches requiring specialized techniques and involved experimentation (beyond the reach of an average laboratory) are covered in theory with suitable references to guide readers. The book provides students, researchers and academics in the broad area of biology with a sound theoretical and practical knowledge of enzymes. It also caters to those who do not have a practicing enzymologist to teach them the subject.

Author : Robert A. Copeland
Publisher : John Wiley & Sons
Page : 581 pages
File Size : 50,7 Mb
Release : 2023-03-01
Category : Science
ISBN : 9781119793250

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Enzymes by Robert A. Copeland Pdf

ENZYMES A complete and approachable introduction to the study of enzymes, from theory to practice Enzymes catalyze the bulk of important biological processes, both metabolic and biochemical. They are specialized proteins whose function is determined by their structure, understanding which is therefore a key focus of biological, pharmacological, and agrarian research, among many others. A thorough knowledge of enzyme structure, pathways, and mechanisms is a fundamental building block of the life sciences and all others connected to them. Enzymes offers a detailed introduction to this critical subject. It analyzes enzyme proteins at the structural level and details the mechanisms by which they perform their catalyzing functions. The book’s in-depth engagement with primary literature and up-to-date research allows it to continuously deploy illustrative examples and connect readers with further research on key subjects. Fully updated after decades as the standard text, this book unlocks a thriving field of biological and biochemical research. Readers of the third edition of Enzymes will also find: Expanded chapters on steady-state and transient-state enzyme kinetics, structural components of enzymes, and more New chapters on enzyme regulation, enzyme-macromolecule interactions, enzyme evolution, and enzymes in human health Key Learning Points at the beginning of each chapter to assist students and instructors Enzymes promises to continue as the standard reference on this subject for practitioners of the life sciences and related fields in both academia and industry.

Author : Hans Bisswanger
Publisher : John Wiley & Sons
Page : 533 pages
File Size : 51,6 Mb
Release : 2019-11-06
Category : Science
ISBN : 9783527820801

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Practical Enzymology by Hans Bisswanger Pdf

A practice-oriented guide to assaying more than 100 of the most important enzymes, complete with the theoretical background and specific protocols for immediate use in the biochemical laboratory. Now expanded with a new section on metal ion determination.

Author : Richard P. Dick
Publisher : John Wiley & Sons
Page : 416 pages
File Size : 43,8 Mb
Release : 2020-01-22
Category : Technology & Engineering
ISBN : 9780891188544

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Methods of Soil Enzymology by Richard P. Dick Pdf

Methods of Soil Enzymology provides the first comprehensive set of vetted methods for studying enzymes in soils. Readers will especially benefit from the step-by-step explanation of the lab procedures, as well as background information for using these methods effectively and analyzing data. Main topics include activity assays, enzyme extraction, and synthetic enzyme complexes. Each method covered includes background informaton, step-by-step descriptions of the procedure, and special comments regarding nuances, pitfalls, and interpretation of the method. Learn the latest research methods, including enzyme extraction methods and procedures for creating synthetic enzyme complexes, as well as the newest ways to use small-scale and high-throughput methods for enzyme activity assays. Written for the researcher, but welcoming to those new to soil enzymology, the introduction includes conceptual information to orient those who are not familiar with these methods but want to use them. In the tradition of SSSA methods books, Methods of Soil Enzymology features a comprehensive approach with a focus on ease of use.

Author : Haruo Suzuki
Publisher : CRC Press
Page : 222 pages
File Size : 45,8 Mb
Release : 2019-08-22
Category : Medical
ISBN : 9781000681437

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How Enzymes Work by Haruo Suzuki Pdf

The first edition of this book covered the basic treatment of the enzyme reaction using the overall reaction kinetics and stopped-flow method, the general properties of protein and cofactors, the control of enzyme reaction, and the preparation of enzyme protein. These topics are the basis of enzyme research and thus suitable for the beginner in the field. The second edition presents the cofactors produced via the post-translational modification of the enzyme’s active site. These cofactors expand the function of enzymes and open a new research field. The carbonyl reagent phenylhydrazine and related compounds have been useful in finding some of the newly discovered cofactors and thus have been discussed in this edition. The topic of the control of enzyme activity through the channel of substrates and products in polyfunctional enzymes has also been expanded in this book.

Author : John C. Griffiths
Publisher : Unknown
Page : 232 pages
File Size : 40,7 Mb
Release : 1979
Category : Medical
ISBN : UOM:39015003808634

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Clinical Enzymology by John C. Griffiths Pdf

Author : Paul Engel
Publisher : Oxford University Press, USA
Page : 193 pages
File Size : 44,8 Mb
Release : 2020-11-11
Category : Medical
ISBN : 9780198824985

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Enzymes: a Very Short Introduction by Paul Engel Pdf

Enzymes are the molecular machines that make life possible. Working as catalysts, teams of enzymes carry out the processes that power the bodies of living things, from making DNA to digesting food. This book explains what enzymes are, what they do, and how they do it, from enzymes inside our cells to those in washing powders and food production.

Author : Alan Wiseman,Barry James Gould
Publisher : Hutchinson
Page : 136 pages
File Size : 40,5 Mb
Release : 1971
Category : Science
ISBN : UOM:39015000291750

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Enzymes, Their Nature and Role by Alan Wiseman,Barry James Gould Pdf

London : Hutchinson Educational, c1971.