Investigating The Human Brainstem With Structural And Functional Mri

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Investigating the human brainstem with structural and functional MRI

Florian Beissner, Simon Baudrexel
Investigating the human brainstem with structural and functional MRI Book PDF

Author : Florian Beissner, Simon Baudrexel
Publisher : Frontiers E-books
Page : 93 pages
File Size : 47,5 Mb
Release : 2014-07-30
Category : Neurosciences. Biological psychiatry. Neuropsychiatry
ISBN : 9782889192472

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Investigating the human brainstem with structural and functional MRI by Florian Beissner, Simon Baudrexel Pdf

The brainstem is one of the least understood parts of the human brain despite its prime importance for the maintenance of basic vital functions. Owing to its role as a relay station between spinal cord, cerebellum and neocortex, the brainstem contains vital nodes of all functional systems in the central nervous system, including the visual, auditory, gustatory, vestibular, somatic and visceral senses, and the somatomotor as well as autonomic nervous systems. While the brainstem has been extensively studied in animals using invasive methods, human studies remain scarce. Magnetic resonance imaging (MRI) as a non-invasive and widely available method is one possibility to access the brainstem in humans and measure its structure as well as function. The close vicinity of the brainstem to large arteries and ventricles and the small size of the anatomical structures, however, place high demands on imaging as well as data analysis methods. Nevertheless, the field of brainstem-(f)MRI has significantly advanced in the past few years, largely due to the development of several new tools that facilitate studying this critical part of the human brain. Within this scope, the goal of this Research Topic is to compile work representing the state of the art in functional and structural MRI of the human brainstem.

Neuroimaging of Pain

Luca Saba
Neuroimaging of Pain Book PDF

Author : Luca Saba
Publisher : Springer
Page : 508 pages
File Size : 46,6 Mb
Release : 2017-06-08
Category : Medical
ISBN : 9783319480466

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Neuroimaging of Pain by Luca Saba Pdf

Authored by world renowned scientists, this book expertly reviews all the imaging techniques and exciting new methods for the analysis of the pain, including novel tracers, biomarker, metabolomic and gene-array profiling, together with cellular, genetic, and molecular approaches. Recent advances in human brain imaging techniques have allowed a better understand of the functional connectivity in pain pathways, as well as the functional and anatomical alterations that occur in chronic pain patients. Modern imaging techniques have permitted rapid progress in the understanding of networks in the brain related to pain processing and those related to different types of pain modulation. Neuroimaging of Pain is designed to be a valuable resource for radiologists, neuroradiologists, neurologists and neuroscientists, working in hospitals and universities from junior trainees to consultants.

Atlas of the Human Brainstem

George Paxinos,Xu-Feng Huang
Atlas of the Human Brainstem Book PDF

Author : George Paxinos,Xu-Feng Huang
Publisher : Elsevier
Page : 150 pages
File Size : 42,6 Mb
Release : 2013-10-22
Category : Science
ISBN : 9780080925219

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Atlas of the Human Brainstem by George Paxinos,Xu-Feng Huang Pdf

Work on the human brainstem has been impeded by the unavailability of a comprehensive diagrammatic and photographic atlas. In the authors' preliminary work on the morphology of the human brainstem (The Human Nervous System, 1990), Paxinos et al demonstrated that it is possible to use chemoarchitecture to establish a number of human homologs in structures known to exist in the rat, the most extensively studied species. Now, with the first detailed atlas on the human brainstem in more than forty years, the authors present an accurate, comprehensive, and convenient reference for students, researchers, and pathologists. Key Features * The first detailed atlas on the human brainstem in more than forty years * Delineated as accurately as The Rat Brain in Stereotaxic Coordinates, Second Edition (Paxinos/Watson, 1986), the most cited book in neuroscience * Based on a single brain from a 59-year-old male with no medical history of neurological or psychiatric illness * Represents all areas of the medulla, pons, and midbrain in the plane transverse to the longitudinal axis of the brainstem * Consists of 64 plates and 64 accompanying diagrams with an interplate distance of half a millimeter * The photographs are of Nissl and acetylcholinesterase (AChE) stained sections at alternate levels * Establishes systematically the human homologs to nuclei identified in the brainstem of the rat Reviewed by leading neuroanatomists * An accurate and convenient guide for students, researchers, and pathologists

Duvernoy's Atlas of the Human Brain Stem and Cerebellum

Thomas P. Naidich,Henri M. Duvernoy,Bradley N. Delman,A. Gregory Sorensen,Spyros S. Kollias,E. Mark Haacke
Duvernoy s Atlas of the Human Brain Stem and Cerebellum Book PDF

Author : Thomas P. Naidich,Henri M. Duvernoy,Bradley N. Delman,A. Gregory Sorensen,Spyros S. Kollias,E. Mark Haacke
Publisher : Springer Science & Business Media
Page : 872 pages
File Size : 54,6 Mb
Release : 2009-06-25
Category : Medical
ISBN : 9783211739716

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Duvernoy's Atlas of the Human Brain Stem and Cerebellum by Thomas P. Naidich,Henri M. Duvernoy,Bradley N. Delman,A. Gregory Sorensen,Spyros S. Kollias,E. Mark Haacke Pdf

This atlas instills a solid knowledge of anatomy by correlating thin-section brain anatomy with corresponding clinical magnetic resonance images in axial, coronal, and sagittal planes. The authors correlate advanced neuromelanin imaging, susceptibility-weighted imaging, and diffusion tensor tractography with clinical 3 and 4 T MRI. Each brain stem region is then analyzed with 9.4 T MRI to show the anatomy of the medulla, pons, midbrain, and portions of the diencephalonin with an in-plane resolution comparable to myelin- and Nissl-stained light microscopy. The book’s carefully organized diagrams and images teach with a minimum of text.

The Circuitry of the Human Spinal Cord

Emmanuel Pierrot-Deseilligny,David Burke
The Circuitry of the Human Spinal Cord Book PDF

Author : Emmanuel Pierrot-Deseilligny,David Burke
Publisher : Unknown
Page : 666 pages
File Size : 49,8 Mb
Release : 2006-05-23
Category : Medical
ISBN : 9780511124167

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The Circuitry of the Human Spinal Cord by Emmanuel Pierrot-Deseilligny,David Burke Pdf

Surveys the control of human spinal cord circuits, in normal movement and in disease states.

The Circuitry of the Human Spinal Cord

Emmanuel Pierrot-Deseilligny,David Burke
The Circuitry of the Human Spinal Cord Book PDF

Author : Emmanuel Pierrot-Deseilligny,David Burke
Publisher : Cambridge University Press
Page : 631 pages
File Size : 43,5 Mb
Release : 2012-04-26
Category : Medical
ISBN : 9780521192583

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The Circuitry of the Human Spinal Cord by Emmanuel Pierrot-Deseilligny,David Burke Pdf

A comprehensive review of the corticospinal and spinal contributions to the control of movement in human subjects.

Translational Pain Research

Lawrence Kruger,Alan R Light
Translational Pain Research Book PDF

Author : Lawrence Kruger,Alan R Light
Publisher : CRC Press
Page : 432 pages
File Size : 53,6 Mb
Release : 2009-11-24
Category : Health & Fitness
ISBN : 9781439812105

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Translational Pain Research by Lawrence Kruger,Alan R Light Pdf

One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practicality of clinical trials, Translational Pain Research: From Mouse to Man effectively bridges the gap between basic research and patient care by humanely examining rodent models for pain associated with bone cancer, osteoarthritis, fibromyalgia, and cardiac episodes. Distinguished Team of International Contributors In addition to addressing the groundbreaking technical advances in tract tracing, endocannabinoids, cannabis, gene therapy, siRNA gene studies, and the role of glia, cytokines, P2X receptors and ATP, this book also presents cutting-edge information on: Nociceptor sensitization Muscle nociceptors and metabolite detection Visceral afferents in disease Innovative rodent model for bone cancer pain Highly specific receptor cloning Modular molecular mechanisms relevant to painful neuropathies This sharply focused work also discusses unexpected discoveries derived from brain-imaging studies related to thalamic pain. Translational Pain Research covers the progress made toward bringing laboratory science (much of it at the molecular level) to our understanding of pain phenomena in humans, with the ultimate goal of reducing the suffering that often accompanies pain and its indirect consequences.

The Claustrum

John R. Smythies,Lawrence Edelstein,Vilayanur S. Ramachandran
The Claustrum Book PDF

Author : John R. Smythies,Lawrence Edelstein,Vilayanur S. Ramachandran
Publisher : Academic Press
Page : 408 pages
File Size : 48,9 Mb
Release : 2013-11-11
Category : Science
ISBN : 9780124047228

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The Claustrum by John R. Smythies,Lawrence Edelstein,Vilayanur S. Ramachandran Pdf

The present day is witnessing an explosion of our understanding of how the brain works at all levels, in which complexity is piled on complexity, and mechanisms of astonishing elegance are being continually discovered. This process is most developed in the major areas of the brain, such as the cortex, thalamus, and striatum. The Claustrum instead focuses on a small, remote, and, until recently, relatively unknown area of the brain. In recent years, researchers have come to believe that the claustrum is concerned with consciousness, a bold hypothesis supported by the claustrum’s two-way connections with nearly every other region of the brain and its seeming involvement with multisensory integrations—the hallmark of consciousness. The claustrum, previously in a humble position at the back of the stage, might in fact be the conductor of the brain’s orchestra. The Claustrum brings together leading experts on the claustrum from the varied disciplines of neuroscience, providing a state-of-the-art presentation of what is currently known about the claustrum, promising lines of current research (including epigenetics), and projections of new lines of investigation on the horizon. Develops a unifying hypothesis about the claustrum’s role in consciousness, as well as the integration of sensory information and other higher brain functions. Discusses the involvement of the claustrum with autism, schizophrenia, epilepsy, Alzheimer’s disease, and Parkinson’s disease Coverage of all aspects of the claustrum, from its evolution and development to promising new lines of research, including epigenetics, provides a platform and point of reference for future investigative efforts

Neuroscience in the 21st Century

Donald W. Pfaff,Nora D. Volkow
Neuroscience in the 21st Century Book PDF

Author : Donald W. Pfaff,Nora D. Volkow
Publisher : Springer
Page : 0 pages
File Size : 47,6 Mb
Release : 2016-10-27
Category : Medical
ISBN : 1493934732

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Neuroscience in the 21st Century by Donald W. Pfaff,Nora D. Volkow Pdf

Edited and authored by a wealth of international experts in neuroscience and related disciplines, this key new resource aims to offer medical students and graduate researchers around the world a comprehensive introduction and overview of modern neuroscience. Neuroscience research is certain to prove a vital element in combating mental illness in its various incarnations, a strategic battleground in the future of medicine, as the prevalence of mental disorders is becoming better understood each year. Hundreds of millions of people worldwide are affected by mental, behavioral, neurological and substance use disorders. The World Health Organization estimated in 2002 that 154 million people globally suffer from depression and 25 million people from schizophrenia; 91 million people are affected by alcohol use disorders and 15 million by drug use disorders. A more recent WHO report shows that 50 million people suffer from epilepsy and 24 million from Alzheimer’s and other dementias. Because neuroscience takes the etiology of disease—the complex interplay between biological, psychological, and sociocultural factors—as its object of inquiry, it is increasingly valuable in understanding an array of medical conditions. A recent report by the United States’ Surgeon General cites several such diseases: schizophrenia, bipolar disorder, early-onset depression, autism, attention deficit/ hyperactivity disorder, anorexia nervosa, and panic disorder, among many others. Not only is this volume a boon to those wishing to understand the future of neuroscience, it also aims to encourage the initiation of neuroscience programs in developing countries, featuring as it does an appendix full of advice on how to develop such programs. With broad coverage of both basic science and clinical issues, comprising around 150 chapters from a diversity of international authors and including complementary video components, Neuroscience in the 21st Century in its second edition serves as a comprehensive resource to students and researchers alike.

The Human Nervous System

Charles R. Noback,David A. Ruggiero,Norman L. Strominger,Robert J. Demarest
The Human Nervous System Book PDF

Author : Charles R. Noback,David A. Ruggiero,Norman L. Strominger,Robert J. Demarest
Publisher : Springer Science & Business Media
Page : 500 pages
File Size : 55,9 Mb
Release : 2005
Category : Medical
ISBN : 1588290409

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The Human Nervous System by Charles R. Noback,David A. Ruggiero,Norman L. Strominger,Robert J. Demarest Pdf

In this work, the authors integrate three major basic themes of neuroscience to serve as an introduction and review of the subject.

Neuroimaging in Developmental Clinical Neuroscience

Judith M. Rumsey,Monique Ernst
Neuroimaging in Developmental Clinical Neuroscience Book PDF

Author : Judith M. Rumsey,Monique Ernst
Publisher : Cambridge University Press
Page : 473 pages
File Size : 54,8 Mb
Release : 2009-02-19
Category : Medical
ISBN : 9781139476751

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Neuroimaging in Developmental Clinical Neuroscience by Judith M. Rumsey,Monique Ernst Pdf

Modern neuroimaging offers tremendous opportunities for gaining insights into normative development and a wide array of developmental neuropsychiatric disorders. Focusing on ontogeny, this text covers basic processes involved in both healthy and atypical maturation, and also addresses the range of neuroimaging techniques most widely used for studying children. This book will enable you to understand normative structural and functional brain maturation and the mechanisms underlying basic developmental processes; become familiar with current knowledge and hypotheses concerning the neural bases of developmental neuropsychiatric disorders; and learn about neuroimaging techniques, including their unique strengths and limitations. Coverage includes normal developmental processes, atypical processing in developmental neuropsychiatric disorders, ethical issues, neuroimaging techniques and their integration with psychopharmacologic and molecular genetic research approaches, and future directions. This comprehensive volume is an essential resource for neurologists, neuropsychologists, psychiatrists, pediatricians, and radiologists concerned with normal development and developmental neuropsychiatric disorders.

Advanced Brain Neuroimaging Topics in Health and Disease

Dorina Papageorgiou,George Christopoulos,Stelios Smirnakis
Advanced Brain Neuroimaging Topics in Health and Disease Book PDF

Author : Dorina Papageorgiou,George Christopoulos,Stelios Smirnakis
Publisher : BoD – Books on Demand
Page : 682 pages
File Size : 55,6 Mb
Release : 2014-05-31
Category : Science
ISBN : 9789535112037

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Advanced Brain Neuroimaging Topics in Health and Disease by Dorina Papageorgiou,George Christopoulos,Stelios Smirnakis Pdf

The brain is the most complex computational device we know, consisting of highly interacting and redundant networks of areas, supporting specific brain functions. The rules by which these areas organize themselves to perform specific computations have only now started to be uncovered. Advances in non-invasive neuroimaging technologies have revolutionized our understanding of the functional anatomy of cortical circuits in health and disease states, which is the focus of this book. The first section of this book focuses on methodological issues, such as combining functional MRI technology with other brain imaging modalities. The second section examines the application of brain neuroimaging to understand cognitive, visual, auditory, motor and decision-making networks, as well as neurological diseases. The use of non-invasive neuroimaging technologies will continue to stimulate an exponential growth in understanding basic brain processes, largely as a result of sustained advances in neuroimaging methods and applications.

Ultra High Field Magnetic Resonance Imaging

Pierre-Marie Robitaille,Lawrence Berliner
Ultra High Field Magnetic Resonance Imaging Book PDF

Author : Pierre-Marie Robitaille,Lawrence Berliner
Publisher : Springer Science & Business Media
Page : 475 pages
File Size : 43,5 Mb
Release : 2007-12-31
Category : Medical
ISBN : 9780387496481

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Ultra High Field Magnetic Resonance Imaging by Pierre-Marie Robitaille,Lawrence Berliner Pdf

The foundation for understanding the function and dynamics of biological systems is not only knowledge of their structure, but the new methodologies and applications used to determine that structure. This volume in Biological Magnetic Resonance emphasizes the methods that involve Ultra High Field Magnetic Resonance Imaging. It will interest researchers working in the field of imaging.

Advanced Imaging in Biology and Medicine

Ch.W. Sensen,Benedikt Hallgrimsson
Advanced Imaging in Biology and Medicine Book PDF

Author : Ch.W. Sensen,Benedikt Hallgrimsson
Publisher : Springer Science & Business Media
Page : 447 pages
File Size : 48,9 Mb
Release : 2008-12-03
Category : Medical
ISBN : 9783540689935

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Advanced Imaging in Biology and Medicine by Ch.W. Sensen,Benedikt Hallgrimsson Pdf

A picture says more than a thousand words. This is something that we all know to be true. Imaging has been important since the early days of medicine and bi- ogy, as seen in the anatomical studies of Leonardo Da Vinci or Andreas Vesalius. More than 100 years ago, the ?rst noninvasive imaging technologies, such as K- rad Roentgen’s X-ray technology,were applied to the medical ?eld—and while still crude—revolutionized medical diagnosis. Today, every patient will be exposed to some kind of advanced imaging technology such as medical resonance imaging, computed tomography or four-dimensional ultrasound during their lifetime. Many diseases, such as brain tumors, are initially diagnosed solely by imaging, and most of the surgical planning relies on the patient imagery. 4D ultrasound is available to expecting parents who wish to create unique early memories of the new baby, and it may soon be used for the morphometric diagnosis of malformations that may one day be treatable—inutero! Light and electron microscopy are unequal brethren, which have contributed to most of our knowledge about the existence and organization of cells, tissues and microorganisms. Every student of biology or medicine is introduced to the fascinating images of the microcosm. New advances have converted these im- ing technologies, which were considered by many to be antiquated, into powerful tools for research in systems biology and related ?elds.

Neuroimaging of Sleep and Sleep Disorders

Eric Nofzinger,Pierre Maquet,Michael J. Thorpy
Neuroimaging of Sleep and Sleep Disorders Book PDF

Author : Eric Nofzinger,Pierre Maquet,Michael J. Thorpy
Publisher : Cambridge University Press
Page : 445 pages
File Size : 43,5 Mb
Release : 2013-03-07
Category : Medical
ISBN : 9781107018631

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Neuroimaging of Sleep and Sleep Disorders by Eric Nofzinger,Pierre Maquet,Michael J. Thorpy Pdf

An up-to-date, superbly illustrated practical guide to the effective use of neuroimaging in the patient with sleep disorders. The only book to date to provide comprehensive coverage of this topic. A must for all healthcare workers interested in understanding the causes, consequences and treatment of sleep disorders.