Isolated Adult Cardiomyocytes

Author : Hans Michael Piper,Gerrit Isenberg
Publisher : CRC-Press
Page : 304 pages
File Size : 54,8 Mb
Release : 1989-03-31
Category : Medical
ISBN : 0849347424

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Isolated Adult Cardiomyocytes by Hans Michael Piper,Gerrit Isenberg Pdf

Written with contributions from experts who have critically evaluated the state of the art and the prospects of isolated adults cardiac myocytes in cardiological research, this two-volume publication summarizes the current knowledge of this technology. The methodology, structure, and metabolism of cardiomyocytes are presented, along with metabolism and cation homeostasis and energy metabolism and hypoxic injury. Additionally, cell isolation and culture and the structure and biochemistry of the sarcolemma is explained. Electrophysiology and contractile function with ionic currents and membrane channels is discussed. Also, the electro-physiological effects of transmitters and hormones are presented, with excitation-contraction coupling and the use of cardiomyocytes in drug design and research explained.

Author : Hans Michael Piper,Gerrit Isenberg
Publisher : CRC Press
Page : 470 pages
File Size : 43,9 Mb
Release : 2019-07-17
Category : Medical
ISBN : 9781000697469

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Isolated Adult Cardiomyocytes by Hans Michael Piper,Gerrit Isenberg Pdf

First published in 1989, written with contributions from experts who have critically evaluated the state of the art and the prospects of isolated adults cardiac myocytes in cardiological research, this two-volume publication summarizes the current knowledge of this technology. The methodology, structure, and metabolism of cardiomyocytes are presented, along with metabolism and cation homeostasis and energy metabolism and hypoxic injury. Additionally, cell isolation and culture and the structure and biochemistry of the sarcolemma is explained. Electrophysiology and contractile function with ionic currents and membrane channels is discussed. Also, the electro-physiological effects of transmitters and hormones are presented, with excitation-contraction coupling and the use of cardiomyocytes in drug design and research explained.

Author : Hans Michael Piper,Gerrit Isenberg
Publisher : CRC-Press
Page : 312 pages
File Size : 49,6 Mb
Release : 1989-03-31
Category : Medical
ISBN : 0849347424

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Isolated Adult Cardiomyocytes by Hans Michael Piper,Gerrit Isenberg Pdf

Written with contributions from experts who have critically evaluated the state of the art and the prospects of isolated adults cardiac myocytes in cardiological research, this two-volume publication summarizes the current knowledge of this technology. The methodology, structure, and metabolism of cardiomyocytes are presented, along with metabolism and cation homeostasis and energy metabolism and hypoxic injury. Additionally, cell isolation and culture and the structure and biochemistry of the sarcolemma is explained. Electrophysiology and contractile function with ionic currents and membrane channels is discussed. Also, the electro-physiological effects of transmitters and hormones are presented, with excitation-contraction coupling and the use of cardiomyocytes in drug design and research explained.

Author : H.M. Piper,P.G. Spieckermann
Publisher : Springer Science & Business Media
Page : 271 pages
File Size : 46,5 Mb
Release : 2013-04-17
Category : Medical
ISBN : 9783662110416

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Adult heart muscle cells by H.M. Piper,P.G. Spieckermann Pdf

With this volume results become generally available of a recent conference that was the first to discuss properties of isolated heart muscle cells from the adult myocardium as a new cardio logical research tool. The conference was held as an International Erwin Riesch Symposium un der the auspices of the Deutsche Gesellschaft fUr Herz- und Kreislaufforschung at Spangenberg Castle, March 22-25, 1984. It was made possible through funding by the Erwin Riesch Foun dation and the Bayer AG which deserve our gratitude for their generosity. It may not be fully reflected in this collection of papers that the atmosphere of this meeting was unique. The reason for this resided apparently in the still rudimentary experiences with the adult cardiocyte model that is now widely acknowledged to be very promising. Thus, quite basic inter ests brought together experts from different biological disciplines who in respect to this new mod el were all still "beginners". It was noteworthy that such common interests exerted a unifying effect upon otherwise rather separated fields of science. The main task of the years to come will certainly consist in improving isolation and culturing conditions for adult myocytes in order to fully establish the isolated cell model in heart research

Author : Hans Michael Piper,Gerrit Isenberg
Publisher : CRC Press
Page : 332 pages
File Size : 55,9 Mb
Release : 2019-07-17
Category : Medical
ISBN : 9781000694383

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Isolated Adult Cardiomyocytes by Hans Michael Piper,Gerrit Isenberg Pdf

First published in 1989, written with contributions from experts who have critically evaluated the state of the art and the prospects of isolated adults cardiac myocytes in cardiological research, this two-volume publication summarizes the current knowledge of this technology. The methodology, structure, and metabolism of cardiomyocytes are presented, along with metabolism and cation homeostasis and energy metabolism and hypoxic injury. Additionally, cell isolation and culture and the structure and biochemistry of the sarcolemma is explained. Electrophysiology and contractile function with ionic currents and membrane channels is discussed. Also, the electro-physiological effects of transmitters and hormones are presented, with excitation-contraction coupling and the use of cardiomyocytes in drug design and research explained.

Author : P. G. Spieckermann,H. M. Piper
Publisher : Springer
Page : 208 pages
File Size : 43,7 Mb
Release : 1985
Category : Calcium
ISBN : 3798506701

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Isolated Adult Cardiac Myocytes by P. G. Spieckermann,H. M. Piper Pdf

Author : William A. Clark,Robert S. Decker,Thomas Keith Borg
Publisher : Elsevier Publishing Company
Page : 464 pages
File Size : 40,5 Mb
Release : 1988
Category : Medical
ISBN : UOM:39015012580331

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Biology of Isolated Adult Cardiac Myocytes by William A. Clark,Robert S. Decker,Thomas Keith Borg Pdf

Author : Fernando Vivanco
Publisher : Springer Science & Business Media
Page : 412 pages
File Size : 46,8 Mb
Release : 2008-02-05
Category : Science
ISBN : 9781597452144

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Cardiovascular Proteomics by Fernando Vivanco Pdf

This cutting-edge book presents protocols and strategies for proteomic evaluation of cardiovascular disease written by pioneering researchers in the field. Topics explored in this comprehensive volume include obtaining specific heart proteins, techniques for identifying risk biomarkers of atherome plaque rupture, analyzing the secretome of explanted endarterectomies cultured in vitro, and phage display techniques for deciphering the molecular diversity of blood vessels.

Author : Nair Sreejayan,Jun Ren
Publisher : Springer Science & Business Media
Page : 370 pages
File Size : 55,9 Mb
Release : 2008-07-25
Category : Science
ISBN : 9781588295743

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Vascular Biology Protocols by Nair Sreejayan,Jun Ren Pdf

Over the past decades, the pathogenesis, diagnosis, treatment and prevention of cardiovascular diseases have been benefited significantly from intensive research activities. In order to provide a comprehensive “manual” in a field that has become as broad and deep as cardiovascular medicine, this volume of “Methods in Molecular Medicine” covers a wide spectrum of in vivo and in vitro techniques encompassing biochemical, pharmacological and molecular biology disciplines which are currently used to assess vascular disease progression. Each chapter included in this volume focuses on a specific vascular biology technique and describes various applications as well as caveats of these techniques. The protocols included here are described in detail, allowing beginners with little experience in the field of vascular biology to embark on new research projects.

Author : Ivan Bertoncello
Publisher : Unknown
Page : 315 pages
File Size : 43,6 Mb
Release : 2019
Category : Electronic
ISBN : 1493990861

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Mouse Cell Culture by Ivan Bertoncello Pdf

Author : G. Michael Felker,Douglas L. Mann
Publisher : Elsevier Health Sciences
Page : 784 pages
File Size : 55,7 Mb
Release : 2019-02-06
Category : Medical
ISBN : 9780323609883

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Heart Failure: A Companion to Braunwald's Heart Disease E-Book by G. Michael Felker,Douglas L. Mann Pdf

Up-to-date, authoritative and comprehensive, Heart Failure, 4th Edition, provides the clinically relevant information you need to effectively manage and treat patients with this complex cardiovascular problem. This fully revised companion to Braunwald’s Heart Disease helps you make the most of new drug therapies such as angiotensin receptor neprilysin inhibitors (ARNIs), recently improved implantable devices, and innovative patient management strategies. Led by internationally recognized heart failure experts Dr. G. Michael Felker and Dr. Douglas Mann, this outstanding reference gives health care providers the knowledge to improve clinical outcomes in heart failure patients. Focuses on a clinical approach to treating heart failure, resulting from a broad variety of cardiovascular problems. Covers the most recent guidelines and protocols, including significant new updates to ACC, AHA, and HFSA guidelines. Covers key topics such as biomarkers and precision medicine in heart failure and new data on angiotensin receptor neprilysin inhibitors (ARNIs). Contains four new chapters: Natriuretic Peptides in Heart Failure; Amyloidosis as a Cause of Heart Failure; HIV and Heart Failure; and Neuromodulation in Heart Failure. Covers the pathophysiological basis for the development and progression of heart failure. Serves as a definitive resource to prepare for the ABIM’s Heart Failure board exam. 2016 British Medical Association Award: First Prize, Cardiology (3rd Edition).

Author : Chandrasekharan C. Kartha
Publisher : Springer Nature
Page : 356 pages
File Size : 54,8 Mb
Release : 2021-09-13
Category : Science
ISBN : 9783030855369

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Cardiomyocytes in Health and Disease by Chandrasekharan C. Kartha Pdf

This book is a treatise on cardiomyocytes, the most important cell for the contractile function of the heart. There has been significant progress in our understanding of the function-related structure, developmental processes and their determinants, mechanisms of cell cycle regulation, post-natal growth, energy metabolism, and reversible and irreversible response of cardiomyocytes to diverse forms of physiological stress and injury. There is also more clarity on the alterations in the biological mechanisms in cardiomyocytes that lead to pathological states and the changes in the cells that occur secondary to disease conditions. Thanks to these advances in knowledge, there have been great gains in attempts to identify disease biomarkers and therapeutic targets for better management of patients with heart diseases. Possibilities to induce regeneration or proliferation of cardiomyocytes and thus repair and or regenerate the damaged heart are also on the horizon.

Author : Paul Delgado-Olguin
Publisher : Humana Press
Page : 193 pages
File Size : 41,6 Mb
Release : 2018-03-22
Category : Science
ISBN : 149397713X

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Mouse Embryogenesis by Paul Delgado-Olguin Pdf

This volume explores protocols for identifying mutant mice and characterizing parts of their anatomical, functional, cellular, and molecular phenotypes. The chapters in this book look at anatomical and functional phenotyping using quantitative imaging, isolation of specific embryonic cell types for cell culture, analysis of gene expression, and how to define chromatin structure. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Mouse Embryogenesis: Methods and Protocols is a valuable resource for experimentalists interested in discovering new aspects of embryogenesis control, organ function, and the origin of disease.

Author : Hossein Ardehali,Roberto Bolli,Douglas W. Losordo
Publisher : John Wiley & Sons
Page : 1 pages
File Size : 42,6 Mb
Release : 2013-12-16
Category : Medical
ISBN : 9781118495131

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Manual of Research Techniques in Cardiovascular Medicine by Hossein Ardehali,Roberto Bolli,Douglas W. Losordo Pdf

While some research methods or techniques are applicable in several areas of medicine, research in cardiovascular diseases requires knowledge of an increasing array of procedures, techniques and measurements that are highly specialized and unique to this area of investigation. Edited by senior clinical investigators who are recognized leaders in cardiovascular medicine worldwide, this book provides readers with a comprehensive, practical “how-to-do-it” review of best-practice techniques for cardiovascular research.

Author : Joanna Gruszczynska-Biegala,Francisco Javier Martin-Romero,Agnese Secondo,Tarik Smani
Publisher : Frontiers Media SA
Page : 199 pages
File Size : 44,5 Mb
Release : 2021-12-01
Category : Science
ISBN : 9782889717569

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Molecular Components of Store-Operated Calcium Entry in Health and Disease by Joanna Gruszczynska-Biegala,Francisco Javier Martin-Romero,Agnese Secondo,Tarik Smani Pdf