Issues In Discovery Experimental And Laboratory Medicine 2012 Edition

Author : Anonim
Publisher : ScholarlyEditions
Page : 440 pages
File Size : 46,8 Mb
Release : 2013-01-10
Category : Medical
ISBN : 9781481645904

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Issues in Discovery, Experimental, and Laboratory Medicine: 2012 Edition by Anonim Pdf

Issues in Discovery, Experimental, and Laboratory Medicine: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Medical Research. The editors have built Issues in Discovery, Experimental, and Laboratory Medicine: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Medical Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Discovery, Experimental, and Laboratory Medicine: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Anonim
Publisher : ScholarlyEditions
Page : 1142 pages
File Size : 40,9 Mb
Release : 2013-05-01
Category : Medical
ISBN : 9781490109169

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Issues in Discovery, Experimental, and Laboratory Medicine: 2013 Edition by Anonim Pdf

Issues in Discovery, Experimental, and Laboratory Medicine: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Free Radical Research. The editors have built Issues in Discovery, Experimental, and Laboratory Medicine: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Free Radical Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Discovery, Experimental, and Laboratory Medicine: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Anonim
Publisher : ScholarlyEditions
Page : 5507 pages
File Size : 52,8 Mb
Release : 2012-01-09
Category : Medical
ISBN : 9781464963506

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Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition by Anonim Pdf

Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Discovery, Experimental, and Laboratory Medicine. The editors have built Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Discovery, Experimental, and Laboratory Medicine in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Anonim
Publisher : ScholarlyEditions
Page : 3455 pages
File Size : 52,6 Mb
Release : 2012-01-09
Category : Medical
ISBN : 9781464963513

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Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition by Anonim Pdf

Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Discovery, Experimental, and Laboratory Medicine. The editors have built Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Discovery, Experimental, and Laboratory Medicine in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Jason Baron
Publisher : Elsevier Health Sciences
Page : 161 pages
File Size : 54,5 Mb
Release : 2023-02-10
Category : Medical
ISBN : 9780323939843

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Artificial Intelligence in the Clinical Laboratory: Current Practice and Emerging Opportunities, An Issue of the Clinics in Laboratory Medicine, E-Book by Jason Baron Pdf

In this issue, guest editors bring their considerable expertise to this important topic. Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize

Author : Institute of Medicine,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders
Publisher : National Academies Press
Page : 118 pages
File Size : 53,6 Mb
Release : 2014-02-06
Category : Medical
ISBN : 9780309292498

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Improving and Accelerating Therapeutic Development for Nervous System Disorders by Institute of Medicine,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders Pdf

Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials.

Author : P. Michael Conn
Publisher : Academic Press
Page : 1108 pages
File Size : 48,8 Mb
Release : 2013-05-29
Category : Science
ISBN : 9780124159129

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Animal Models for the Study of Human Disease by P. Michael Conn Pdf

Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine.The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders, cancer, hypertension, genetic diseases, and diseases of abuse. Organized by disease orientation for ease of searchability Provides information on locating resources, animal alternatives and animal ethics Covers a broad range of animal models used in research for human disease

Author : National Academies of Sciences, Engineering, and Medicine,Policy and Global Affairs,Committee on Science, Engineering, Medicine, and Public Policy,Board on Research Data and Information,Division on Engineering and Physical Sciences,Committee on Applied and Theoretical Statistics,Board on Mathematical Sciences and Analytics,Division on Earth and Life Studies,Nuclear and Radiation Studies Board,Division of Behavioral and Social Sciences and Education,Committee on National Statistics,Board on Behavioral, Cognitive, and Sensory Sciences,Committee on Reproducibility and Replicability in Science
Publisher : National Academies Press
Page : 257 pages
File Size : 40,9 Mb
Release : 2019-10-20
Category : Science
ISBN : 9780309486163

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Reproducibility and Replicability in Science by National Academies of Sciences, Engineering, and Medicine,Policy and Global Affairs,Committee on Science, Engineering, Medicine, and Public Policy,Board on Research Data and Information,Division on Engineering and Physical Sciences,Committee on Applied and Theoretical Statistics,Board on Mathematical Sciences and Analytics,Division on Earth and Life Studies,Nuclear and Radiation Studies Board,Division of Behavioral and Social Sciences and Education,Committee on National Statistics,Board on Behavioral, Cognitive, and Sensory Sciences,Committee on Reproducibility and Replicability in Science Pdf

One of the pathways by which the scientific community confirms the validity of a new scientific discovery is by repeating the research that produced it. When a scientific effort fails to independently confirm the computations or results of a previous study, some fear that it may be a symptom of a lack of rigor in science, while others argue that such an observed inconsistency can be an important precursor to new discovery. Concerns about reproducibility and replicability have been expressed in both scientific and popular media. As these concerns came to light, Congress requested that the National Academies of Sciences, Engineering, and Medicine conduct a study to assess the extent of issues related to reproducibility and replicability and to offer recommendations for improving rigor and transparency in scientific research. Reproducibility and Replicability in Science defines reproducibility and replicability and examines the factors that may lead to non-reproducibility and non-replicability in research. Unlike the typical expectation of reproducibility between two computations, expectations about replicability are more nuanced, and in some cases a lack of replicability can aid the process of scientific discovery. This report provides recommendations to researchers, academic institutions, journals, and funders on steps they can take to improve reproducibility and replicability in science.

Author : Callum G. Fraser
Publisher : Amer. Assoc. for Clinical Chemistry
Page : 172 pages
File Size : 53,5 Mb
Release : 2001
Category : Medical
ISBN : 1890883492

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Biological Variation by Callum G. Fraser Pdf

Author : Anol Bhattacherjee
Publisher : CreateSpace
Page : 156 pages
File Size : 42,7 Mb
Release : 2012-04-01
Category : Science
ISBN : 1475146124

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Social Science Research by Anol Bhattacherjee Pdf

This book is designed to introduce doctoral and graduate students to the process of conducting scientific research in the social sciences, business, education, public health, and related disciplines. It is a one-stop, comprehensive, and compact source for foundational concepts in behavioral research, and can serve as a stand-alone text or as a supplement to research readings in any doctoral seminar or research methods class. This book is currently used as a research text at universities on six continents and will shortly be available in nine different languages.

Author : National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee for the Update of the Guide for the Care and Use of Laboratory Animals
Publisher : National Academies Press
Page : 246 pages
File Size : 40,6 Mb
Release : 2011-01-27
Category : Science
ISBN : 9780309154000

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Guide for the Care and Use of Laboratory Animals by National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee for the Update of the Guide for the Care and Use of Laboratory Animals Pdf

A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

Author : Anonim
Publisher : Unknown
Page : 900 pages
File Size : 50,5 Mb
Release : 2013
Category : Communicable diseases
ISBN : STANFORD:36105214546512

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Emerging Infectious Diseases by Anonim Pdf

Author : Michael Bliss
Publisher : University of Toronto Press
Page : 320 pages
File Size : 49,5 Mb
Release : 2017-06-22
Category : Medical
ISBN : 9781487516741

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The Discovery of Insulin by Michael Bliss Pdf

The discovery of insulin at the University of Toronto in 1921-22 was one of the most dramatic events in the history of the treatment of disease. Insulin was a wonder-drug with ability to bring patients back from the very brink of death, and it was no surprise that in 1923 the Nobel Prize for Medicine was awarded to its discoverers, the Canadian research team of Banting, Best, Collip, and Macleod. In this engaging and award-winning account, historian Michael Bliss recounts the fascinating story behind the discovery of insulin – a story as much filled with fiery confrontation and intense competition as medical dedication and scientific genius. Originally published in 1982 and updated in 1996, The Discovery of Insulin has won the City of Toronto Book Award, the Jason Hannah Medal of the Royal Society of Canada, and the William H. Welch Medal of the American Association for the History of Medicine.

Author : Donald T. Campbell,Julian C. Stanley
Publisher : Ravenio Books
Page : 84 pages
File Size : 54,8 Mb
Release : 2015-09-03
Category : Psychology
ISBN : 8210379456XXX

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Experimental and Quasi-Experimental Designs for Research by Donald T. Campbell,Julian C. Stanley Pdf

We shall examine the validity of 16 experimental designs against 12 common threats to valid inference. By experiment we refer to that portion of research in which variables are manipulated and their effects upon other variables observed. It is well to distinguish the particular role of this chapter. It is not a chapter on experimental design in the Fisher (1925, 1935) tradition, in which an experimenter having complete mastery can schedule treatments and measurements for optimal statistical efficiency, with complexity of design emerging only from that goal of efficiency. Insofar as the designs discussed in the present chapter become complex, it is because of the intransigency of the environment: because, that is, of the experimenter’s lack of complete control.

Author : Alberto M. Marchevsky,Mark Wick
Publisher : Springer Science & Business Media
Page : 364 pages
File Size : 43,6 Mb
Release : 2011-07-01
Category : Medical
ISBN : 9781441910301

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Evidence Based Pathology and Laboratory Medicine by Alberto M. Marchevsky,Mark Wick Pdf

Focusing on practical, patient related issues, this volume provides the basic concepts of Evidence Based Medicine (EBM) as they relate to Pathology and Laboratory Medicine and presents various practical applications. It includes EBM concepts for use in the identification of cost-effective panels of immunostains and other laboratory tests and for improvement of diagnostic accuracy based on the identification of selected diagnostic features for particular differential diagnosis. EBM concepts are also put forth for use in Meta-analysis to integrate the results of conflicting literature reports and use of novel analytical tools such as Bayesian belief networks, neural networks, multivariate statistics and decision tree analysis for the development of new diagnostic and prognostic models for the evaluation of patients. This volume will be of great value to pathologists who will benefit from the concepts being promoted by EBM, such as levels of evidence, use of Bayesian statistics to develop diagnostic and other rules and stronger reliance on "hard data" to support therapeutic and diagnostic modalities.