Liver Proteomics

Author : Djuro Josic,Douglas C. Hixson
Publisher : Humana Press
Page : 346 pages
File Size : 52,8 Mb
Release : 2016-08-23
Category : Science
ISBN : 1493962140

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Liver Proteomics by Djuro Josic,Douglas C. Hixson Pdf

The liver is responsible for a wide range of critical functions essential to life, and is composed of several different cell types. In Liver Proteomics: Methods and Protocols, expert researchers in the field detail many of the methods that are used to study the live. These methods include the most up-to-date strategies being used to characterize the liver proteome at the global, cellular, subcellular, post translational and functional level.Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Liver Proteomics: Methods and Protocols seeks to aid scientists in the further study of this crucially important organ.

Author : Aleksander Krag,Torben Hansen
Publisher : Springer
Page : 294 pages
File Size : 48,8 Mb
Release : 2018-11-09
Category : Medical
ISBN : 9783319988900

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The Human Gut-Liver-Axis in Health and Disease by Aleksander Krag,Torben Hansen Pdf

The book brings together the current knowledge and future perspectives of the complex physiology and pathophysiology of gut-liver interactions in health and disease. It provides readers with a unique overview and access to knowledge that cannot be obtained elsewhere. The structure is logical and covers all aspect including the normal physiology, changes in various liver diseases, technology, sample collection and various interventions. Thus suitable for general reading, lookup for specific questions or as a reference book within the area. The book allows the reader to access all the knowledge that has been generated within the last 10 years in this field.

Author : Philip Whitfield,David Eckersall
Publisher : John Wiley & Sons
Page : 464 pages
File Size : 51,7 Mb
Release : 2011-09-13
Category : Science
ISBN : 9780813817910

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Methods in Animal Proteomics by Philip Whitfield,David Eckersall Pdf

The study of proteomics provides researchers with a better understanding of disease and physiological processes in animals. Methods in Animal Proteomics will provide animal scientists and veterinarians currently researching these topics in domestic animals a firm foundation in the basics of proteomics methodology, while also reviewing important advances that will be of interest to established researchers in the field. Chapters will provide practical information on a range of topics including protein identification and separation, bioinformatics, and applications to disease and reproduction research. This text will be written by leading international proteomics experts and essential for researchers in the fields of animal biology and veterinary medicine.

Author : Sanjeeva Srivastava
Publisher : CRC Press
Page : 272 pages
File Size : 54,6 Mb
Release : 2022-12-29
Category : Medical
ISBN : 9781000648676

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From Proteins to Proteomics by Sanjeeva Srivastava Pdf

Proteomics aims to study all the proteins of human and other living systems, as well as their properties to provide an integrated view of cellular processes. The study of proteomics involves the application of rapidly evolving high-throughput technologies and new platforms that are coming forward regularly, providing versatile novel tools for biomedical and pharmaceutical applications. This book provides a detailed understanding of the basics of proteins and proteomics, gel based-proteomics techniques, basics of mass spectrometry and quantitative proteomics, interactomics: basics and applications, and advancements in proteomics. It also covers basic knowledge about sample preparation, mass spectrometry workflow, different chromatography technologies and quantitative proteomics. The text highlights the application and challenges of various high-throughput integrated proteomics technologies capable of fast and accurate screening of thousands of biomolecules, which are found to be very effective for studying disease pathobiology and identification of next-generation biomarkers and potential drug/vaccine targets; and are therefore considered valuable tools for multidisciplinary research. Features Basics of proteins and proteomics techniques In-depth understanding of mass spectrometry and quantitative proteomics An overview of interactomics and its application for translational research Advancement in the field of proteomics and challenges in clinical applications We hope the knowledge gained from reading this book will intrigue and motivate young minds to explore future opportunities in the constantly evolving field of proteomics.

Author : Anonim
Publisher : Unknown
Page : 750 pages
File Size : 51,9 Mb
Release : 2012-11-07
Category : Electronic
ISBN : 3527317147

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The Liver Proteome by Anonim Pdf

Author : Fidel Toldrá,Leo M. L. Nollet
Publisher : Springer Science & Business Media
Page : 589 pages
File Size : 46,9 Mb
Release : 2012-12-16
Category : Technology & Engineering
ISBN : 9781461456261

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Proteomics in Foods by Fidel Toldrá,Leo M. L. Nollet Pdf

Food proteomics is one of the most dynamic and fast-developing areas in food science. The goal of this book is to be a reference guide on the principles and the current and future potential applications of proteomics in food science and technology. More specifically, the book will discuss recent developments and the expected trends of the near future in food proteomics. The book will be divided into two parts. The first part (7 chapters) will focus on the basic principles for proteomics, e.g., sample preparation, such as extraction and separation techniques, analytical instrumentation currently in use, and available databases for peptide and protein identification. The second part of the book (26 chapters) will focus on applications in foods. It will deal with quality issues related to post-mortem processes in animal foods and quality traits for all foods in general, as well as the identification of bioactive peptides and proteins, which are very important from the nutritional point of view. Furthermore, consumers are now extremely susceptible to food safety issues, and proteomics can provide reassurance with different safety aspects, such as food authenticity, detection of animal species in the food, and identification of food allergens. All of these issues will be covered in this book. It is also worth noting that both editors are internationally recognized experts in the field of food science, and both have edited numerous food science books and handbooks.

Author : Luis A. del Río,Michael Schrader
Publisher : Springer
Page : 493 pages
File Size : 50,6 Mb
Release : 2018-10-30
Category : Science
ISBN : 9789811322334

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Proteomics of Peroxisomes by Luis A. del Río,Michael Schrader Pdf

This new edited volume in the Springer Subcellular Biochemistry Series presents a comprehensive, state-of-the-art overview of the proteomics of peroxisomes derived from mammalian, Drosophila, fungal, and plant origin, and contains contributions from leading experts in the field. The development of sensitive proteomics and mass spectrometry technologies, combined with bioinformatics approaches now allow the identification of low-abundance and transient peroxisomal proteins and permits to identify the complete proteome of peroxisomes, with the consequent increase of our knowledge of the metabolic and regulatory networks of these important cellular organelles. The book lines-up with these developments and is organized in four sections including: (i) mass spectrometry-based organelle proteomics; (ii) prediction of peroxisomal proteomes; (iii) analysis of peroxisome proteome interaction networks; and (iv) peroxisomes in relation to other subcellular compartments. The editor Luis A. del Río is Professor ad honorem of the Spanish National Research Council (CSIC) in the Group of Antioxidants, Free Radicals and Nitric Oxide in Biotechnology, Food and Agriculture, Department of Biochemistry and Cell & Molecular Biology of Plants, at the Estación Experimental del Zaidín, Granada, Spain. Del Río’s research group focuses on the metabolism of reactive oxygen species (ROS), reactive nitrogen species (RNS) and antioxidants in plant peroxisomes, and the ROS- and RNS-dependent role of peroxisomes in plant cell signalling. The editor Michael Schrader is Professor of Cell Biology & Cytopathology in the Department of Biosciences at the University of Exeter, UK. Using mammalian peroxisomes as model organelles, Prof. Schrader and his team aim to unravel the molecular machinery and signalling pathways that mediate and regulate the formation, dynamics and abundance of these medically relevant cellular compartments.

Author : Jennifer E. Van Eyk,Michael J. Dunn
Publisher : John Wiley & Sons
Page : 694 pages
File Size : 53,6 Mb
Release : 2008-09-08
Category : Science
ISBN : 9783527622160

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Clinical Proteomics by Jennifer E. Van Eyk,Michael J. Dunn Pdf

Unparalleled in its scope and depth, this book brings together proteomic approaches in diagnosis and treatment from all clinical fields, including clinical toxicology. The result is a new discipline in molecular medicine that will revolutionize the treatment and prevention of cancer, stroke and other severe diseases. Following an overview of clinical proteomics, the authors look at the technologies available, before moving on to cancer, cardiopulmonary disease, diabetes and stroke. A whole section is devoted to toxicity and the work is rounded off with a discussion of the future of clinical proteomics.

Author : Oscar Alzate
Publisher : CRC Press
Page : 356 pages
File Size : 41,8 Mb
Release : 2009-10-26
Category : Medical
ISBN : 9781420076264

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Neuroproteomics by Oscar Alzate Pdf

In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we beg

Author : Michelle Lisa Colgrave
Publisher : Academic Press
Page : 538 pages
File Size : 50,7 Mb
Release : 2017-04-03
Category : Technology & Engineering
ISBN : 9780128040577

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Proteomics in Food Science by Michelle Lisa Colgrave Pdf

Proteomics in Food Science: From Farm to Fork is a solid reference providing concepts and practical applications of proteomics for those in various disciplines of food science. The book covers a range of methods for elucidating the identity or composition of specific proteins in foods or cells related to food science, from spoilage organisms, to edible components. A variety of analytical platforms are described, ranging from the usage of simple electrophoresis, to more sophisticated mass spectrometry and bio-informatic platforms. The book is designed for food scientists, technologists, food industry workers, microbiologists, and public health workers, and can also be a valuable reference book for students. Includes a variety of analytical platforms, ranging from simple electrophoresis to more sophisticated mass spectrometry and bio-informatic platforms Presents analytical techniques for each food domain, including beverages, meats, dairy and eggs, fruit, fish/seafood, cereals, nuts, and grains that range from sample collection, proportion, and storage analysis Provides applications of proteomics in hot topics area of food safety, including food spoilage, pathogenic organisms, and allergens Covers major pathogens of concern e.g., Salmonella and applications to animal husbandry

Author : Hubert Hondermarck
Publisher : Springer Science & Business Media
Page : 396 pages
File Size : 49,6 Mb
Release : 2007-05-08
Category : Medical
ISBN : 9781402023231

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Proteomics: Biomedical and Pharmaceutical Applications by Hubert Hondermarck Pdf

Human biology has now entered into a phase of post-genomics and it might not be an exaggeration to say that the major outcome of the human genome sequencing has finally been to open the way to the exploration of the proteome-proteomics. Proteins are the functional output of genes and there are two main expected outcomes from human proteomics. The first is to discover new molecular markers for early diagnosis and profiling of pathologies. The second is to decipher the intracellular signaling pathways leading to the initiation and progression of pathologies, for the identification of new targets and the development of innovative therapeutic strategies. This is clearly a promising challenge that this book explores through a series of ongoing experiences and projects representative of the new era in which biology and medicine have now entered.

Author : Andrè de Almeida,Fabrizio Ceciliani,David Eckersall,Ingrid Miller,Jenny Renaut,Paola Roncada,Romana Turk
Publisher : BRILL
Page : 289 pages
File Size : 40,7 Mb
Release : 2023-09-04
Category : Technology & Engineering
ISBN : 9789086868100

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Farm animal proteomics 2014 by Andrè de Almeida,Fabrizio Ceciliani,David Eckersall,Ingrid Miller,Jenny Renaut,Paola Roncada,Romana Turk Pdf

Proteomics is the large-scale study of the proteome, i.e. a set of proteins being expressed in a certain fluid, tissue, organ or organism. The value of this advanced technology is being recognised in farm animal and veterinary sciences from 'farm to fork'. The potential of proteomics is unequivocal in holding a significant promise in applications such as vaccine and drug development, physiology, toxicology, animal product quality and food safety. Proteomics has been growing steadily during the last 3-4 years and, as time goes by, proteomics-based studies are more and more common, not just to scientists but to the general public as well, unravelling the full potential of this innovative technology. This book reflects the will of a group of multi-disciplinary scientists that merge innovation with excellence of research and to whom the dissemination of knowledge and discovery through cooperation is a key point. It is of interest to scientists at the early stages of their careers as well as to researchers well established in the field and to whom proteomics may be the necessary next step towards more in-depth research activities. By providing a collection of diverse scientific interests, 'Farm Animal Proteomics 2014' demonstrates the vitality of the area and the importance it holds to animal and food research, to science, industry, government agencies, the consumer and ultimately the society as a whole.

Author : Eric Bertrand,Michel Faupel
Publisher : Springer Science & Business Media
Page : 397 pages
File Size : 51,6 Mb
Release : 2007-08-29
Category : Science
ISBN : 9781402059438

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Subcellular Proteomics by Eric Bertrand,Michel Faupel Pdf

This volume summarizes the new developments that made subcellular proteomics a rapidly expanding area. It examines the different levels of subcellular organization and their specific methodologies. In addition, the book includes coverage of systems biology that deals with the integration of the data derived from these different levels to produce a synthetic description of the cell as a system.

Author : José-Luis Capelo-Martínez
Publisher : Springer
Page : 222 pages
File Size : 54,8 Mb
Release : 2019-06-24
Category : Science
ISBN : 9783030122980

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Emerging Sample Treatments in Proteomics by José-Luis Capelo-Martínez Pdf

Proteomics is a well-established area of Science; yet with a strong area in constant evolution, namely sample treatment. There few books that currently cover the field of emerging sample treatments in proteomics, this new volume will be the first to cover all emerging and existing studies. This unique book presents the latest advances in the field focusing on emerging trends linked to high-resolution mass spectrometry, technology addressed to treat samples faster and to attempts to simplify the proteome for the reader.

Author : Sudhir Srivastava
Publisher : CRC Press
Page : 474 pages
File Size : 54,5 Mb
Release : 2005-06-24
Category : Medical
ISBN : 9781420027624

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Informatics In Proteomics by Sudhir Srivastava Pdf

The handling and analysis of data generated by proteomics investigations represent a challenge for computer scientists, biostatisticians, and biologists to develop tools for storing, retrieving, visualizing, and analyzing genomic data. Informatics in Proteomics examines the ongoing advances in the application of bioinformatics to proteomics researc