Long Circulating Liposomes Old Drugs New Therapeutics
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Long Circulating Liposomes: Old Drugs, New Therapeutics by Martin C. Woodle,Gerrit Storm Pdf
This book provides an up-to-date evaluation of clinical aspects of newly available "long-circulating liposome" formulations. Based on results from numerous clinical studies, the book describes the fundamentals of this new technology, discusses how it may influence the pharmacology of existing well-known agents reformulated in this manner, and elaborates on future expectations. It provides the practicing clinician - in particular, oncologists and critical care infectious disease physicians - with the tools needed to use these new formulations towards the best outcome for the patient.
Long Circulating Liposomes: Old Drugs, New Therapeutics by Martin C. Woodle,Gerrit Storm Pdf
This book provides an up-to-date evaluation of clinical aspects of newly available "long-circulating liposome" formulations. Based on results from numerous clinical studies, the book describes the fundamentals of this new technology, discusses how it may influence the pharmacology of existing well-known agents reformulated in this manner, and elaborates on future expectations. It provides the practicing clinician - in particular, oncologists and critical care infectious disease physicians - with the tools needed to use these new formulations towards the best outcome for the patient.
Cancer Treatment: Conventional and Innovative Approaches is an attempt to integrate into a book volume the various aspects of cancer treatment, compiling comprehensive reviews written by an international team of experts in the field. The volume is presented in six sections: i) Section 1: Cancer treatment: Conventional and innovative pharmacological approaches; ii) Section 2: Combinatorial strategies to fight cancer: Surgery, radiotherapy, backytherapy, chemotherapy, and hyperthermia; iii) Section 3: The immunotherapy of cancer; iv) Section 4: Multidisciplinarity in cancer therapy: nutrition and beyond; v) Section 5: Supportive care for cancer patients; vi) Section 6: Perspectives in cancer biology and modeling. Ultimately, we hope this book can enlighten important issues involved in the management of cancer, summarizing the state-of-the-art knowledge regarding the disease control and treatment; thus, providing means to improve the overall care of patients that daily battle against this potentially lethal condition.
Stealth Liposomes by Danilo D. Lasic,Francis J. Martin Pdf
This book examines stealth liposomes from a multidisciplinary approach, which includes theoretical polymer physics, organic synthesis, colloid science, and biology. Discussions include theory, chemistry, biochemistry, pharmacology, preclinical studies in model systems, and medical applications in humans.
Liposome Technology, Volume III: Interactions of Liposomes with the Biological Milieu, Third Edition, is a comprehensively updated and expanded new edition of a classic text in the field. Including step-by-step technical details, Volume III describes technologies for yielding liposomes that can function in a targeted fashion, and highlights methods
Drug Delivery Nanoparticles Formulation and Characterization by Yashwant Pathak,Deepak Thassu Pdf
Exploring fundamental concepts, Drug Delivery Nanoparticles Formulation and Characterization presents key aspects of nanoparticulate system development for various therapeutic applications and provides advanced methods used to file for regulatory approval.This comprehensive guide features:Process Analytical Techniques (PAT) used in manufacturing Na
Liposomes by Madhumati Bhaskarwar,Anjulika Joshi,Ashok N. Bhaskarwar Pdf
This book throws light on the various methods of preparation and characterization of liposomes. With the advancements in technology since their discovery, newer methods of generating liposomes have been developed. Needless to say, over time liposomes have been modified to a large extent and engineered to suit many of our growing needs. This book throws light on the various methods of preparation and characterization of liposomes. It also discusses the several biochemical and indirect methods that have made it possible to understand the biological and physicochemical mechanisms of liposomes that decide their fate in vivo. In spite of certain limitations, liposomes have proved to be more suitable for a number of unconventional applications. This versatility of liposomes outlined in the book brings out the importance of these nanoparticles in the future applications of nanotechnology besides targeted drug delivery. Overall, this book provides the necessary information about the various aspects of liposomes for beginners.
Nanoparticulate Drug Delivery by Vandana Patravale,Prajakta Dandekar,Ratnesh Jain Pdf
Nanotechnology-based therapeutics, operating at scales of billionths of a metre, have great potential for future expansion in altering the scale and methods of drug delivery. The availability of these novel formulations to once-inaccessible areas of the body has greatly expanded the therapeutic window of existing drug molecules. Nanoparticulate drug delivery highlights and examines the transition of nanoparticulate drug delivery systems from the laboratory into a commercially viable sector. The first chapters of the book provide an overview of the use and characterization of nanoparticulate systems as drug carriers, including the assessment of their morphology, sterility and potential toxicity. In the latter part of the book, chapters cover nanotoxicology, regulatory aspect and clinical trials, ending with an overview of several case studies and a look towards future developments. Discusses the issues surrounding nanoparticulate products, based on personal experience of their formulation Provides an overview of new application areas, including RNA interference Outlines the pros and cons of nanoparticulate products, and discusses how these may influence their route into the commercial sector
Liposomes have received increased attention in recent years. Nevertheless, liposomes, due to their various forms and applications, require further investigation. These structures can deliver both hydrophilic and hydrophobic drugs. Preparation of liposomes results in different properties for these systems. In addition, there are many factors and difficulties that affect the development of liposome drug delivery structure. The purpose of this book is to concentrate on recent developments on liposomes. The articles collected in this book are contributions by invited researchers with a long-standing experience in different research areas. We hope that the material presented here is understandable to a broad audience, not only scientists but also people with general background in many different biological sciences. This volume offers you up-to-date, expert reviews of the fast-moving field of liposomes.
Cellular Drug Delivery by D. Robert Lu,Svein Øie Pdf
An authoritative and up-to-date survey of the fundamental principles, and practice of drug delivery at the cellular level. On the principles side, the authors discuss the broad spectrum of cellular delivery, ranging from coverage of cell-mediated immunity, gene delivery, and protein targeting, to cellular drug transport, cellular drug permeability, and a variety of carrier system related to targeted drug delivery. On the practice side, the authors focus on technological developments in cellular drug delivery, including novel formulations for the delivery of DNA and antisense oligonucleotides ,as well as drug targeting with immunoglobulin formulations and antibody-mediated approaches.
Functional Informatics in Drug Discovery by Sergey Ilyin Pdf
Integrating various technologies with informational systems provides vast improvements to the overall research and development that occur in the biopharmaceutical industry. One of the first books to explore this area, Functional Informatics in Drug Discovery examines all aspects of technology integration and information flow in a biopharmaceutical
In the view of most experts pharmacology is on drugs, targets, and actions. In the context the drug as a rule is seen as an active pharmaceutical ingredient and not as a complex mixture of chemical entities of a well defined structure. Today, we are becoming more and more aware of the fact that delivery of the active compound to the target site is a key. The present volume gives a topical overview on various modern approaches to drug targeting covering today’s options for specific carrier systems allowing successful drug treatment at various sites of the body difficult to address and allowing to increase the benefit-risk-ratio to the optimum possible.
Characterization and Biology of Nanomaterials for Drug Delivery by Shyam Mohapatra,Shivendu Ranjan,Nandita Dasgupta,Raghvendra Kumar,Sabu Thomas Pdf
Characterization and Biology of Nanomaterials for Drug Delivery: Nanoscience and Nanotechnology in Drug Delivery describes the techniques successfully employed for the application of nanocarriers loaded with the antioxidant enzyme, catalase, and thus targeted to endothelial cells. Methods of nanocarrier synthesis, loading within various systems, and the characterization of nanocarriers for targeting activities are covered, as are their advantages, disadvantages and applications. Reflecting the interdisciplinary nature of the subject matter, this book includes contributions by experts from different fields, all with various backgrounds and expertise. It will appeal to researchers and students from different disciplines, such as materials science, technology and various biomedical fields. Enables readers from different fields to access recent research and protocols across traditional boundaries Focuses on protocols and techniques, as well as the knowledge base of the field, thus enabling those in R&D to learn about, and successfully deploy, cutting-edge techniques Explores both current and emerging classes of nanomaterials, along with their fundamentals and applications
Engineered Biomaterials: Progress And Prospects by P A Hassan,Biji Balakrishnan,A K Tyagi Pdf
Engineered Biomaterials: Progress and Prospects presents state-of-the-art developments in the area of biomaterials research exemplified by experts in the fields of tissue engineering, wound healing, bio-diagnostics, novel therapeutics and advanced drug delivery systems.It provides a comprehensive account of preparation, characterisation, properties, processing, biological and clinical evaluation of a large variety of materials for specific biomedical applications. Basic concepts related to wound healing, tissue engineering and drug delivery systems, and the principal role played by macro, micro and nano scaled structures in biomaterials are presented in a clear manner. Developments in the area of conventional and advanced wound care strategies, materials for periodontal therapeutics, in-situ gelling tissue adhesives, biodegradable composites etc are illustrated in a lucid manner. Advanced processing techniques explored for the fabrication of micro-needles for vaccine delivery, 3D printing of personalized pharmaceuticals, bio-resorbable coatings, metallosurfactants and surface engineering of nanosystems are depicted in a straightforward and reasonable way.This book also discusses various advanced therapeutic and diagnostic systems such as magnetic nanoparticle based hyperthermia and their surface functionalization techniques. Lipid-based nano delivery systems for psoriasis, irritable bowel syndrome and pain management, polyrotaxane polymers, wearable devices for sensing etc are also depicted in this book. The contents are designed in a manner that will be highly suited for academic researchers, clinicians and industrialists who wish to explore in the versatile field of biomaterials as it contains a wealth of valuable information that will be equally useful to both beginners as well as established researchers.
Fundamentals and Applications of Controlled Release Drug Delivery by Juergen Siepmann,Ronald A. Siegel,Michael J. Rathbone Pdf
Pitched at a level comprehensible to those new to the field, this authoritative text covers the scientific and technological fundamentals of drug delivery as well as clinical applications and the developmental potential in controlled release drug delivery.
