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Author : Anonim
Publisher : Kendall Hunt
Page : 572 pages
File Size : 54,9 Mb
Release : 2024-06-15
Category : Electronic
ISBN : 0787266094
Author : Peter H. Schur,Elena M. Massarotti
Publisher : Springer Science & Business Media
Page : 266 pages
File Size : 46,7 Mb
Release : 2012-07-06
Category : Medical
ISBN : 9781461411895
Often considered the prototypic autoimmune disease, Lupus is characterized by protean manifestations and affects a wide range of organ systems. Despite widespread availability of anti nuclear antibody testing and other technological diagnostic advances, the diagnosis of lupus can be elusive, difficult, and inexact. Treatment of the disease can also be challenging. Advances in immunology and biotechnology have led to a burgeoning world of new therapies in development that offer patients the real possibility of new therapies and physicians and scientists novel insights into the pathogenesis of this complicated immunological disease. Lupus Erythematosus: Clinical Evaluation and Treatment summarizes the clinical aspects of lupus facing the general clinician in the 21st century. In this invaluable, practical book, the reader will find introductory chapters regarding general diagnostic and treatment principles, followed by chapters addressing the lupus-specific organ manifestations. Special topics regarding pregnancy and comorbidities are also presented. Written by highly experienced physicians with special expertise in lupus, Lupus Erythematosus: Clinical Evaluation and Treatment is an indispensable reference for the common and not so common problems affecting patients with lupus.
Author : Sophia Lionaki
Publisher : BoD – Books on Demand
Page : 140 pages
File Size : 40,5 Mb
Release : 2020-03-25
Category : Medical
ISBN : 9781838801694
Systemic lupus erythematosus, the prototype of an autoimmune disorder, may affect several organs and may run a chronic course between relapse and remission. This book covers important aspects of the disease, including epidemiology, pathophysiology, and neuropsychiatric manifestations, including basic science and clinical features and management. In affected patients, the fundamental problem of fertility is reassessed including the risk of the disease, the possibility of fetal loss, the safety of drugs during pregnancy, and the current diagnostic and suggested therapeutic strategies of reproductive medicine. Finally, the issue of pathogenesis is revisited with a thorough description of animal models in relation to physiology and potential novel therapies.
Author : Graham Robert Vivian Hughes
Publisher : Oxford University Press, USA
Page : 148 pages
File Size : 52,6 Mb
Release : 2000
Category : Connective tissues
ISBN : 0192631454
Offers practical advice about a health condition which predominantly affects young women.
Author : Josef S. Smolen,Christoph C. Zielinski
Publisher : Springer Science & Business Media
Page : 358 pages
File Size : 49,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642716423
More than 140 years ago, lupus erythematosus (LE) was recognized as a disease entity by clinicians working in the field of dermatology, which had only recently become an independent medical discipline. Soon after cutaneous lupus was first reported, it was realized that, apart from the skin, the disease could involve other organs and thus be systemic in nature. The latter observations were first made by MORITZ KApOSI [1], whose work has attracted renewed attention re cently and who succeeded FERDINAND VON HEBRA to the chair of dermatology at the Medical Faculty in Vienna. The early description of lupus erythematosus in both its cutaneous and systemic manifes tations was thus intimately associated with Vienna and its Medical School. The next phase in the study of lupus was characterized by an in crease in knowledge of the type and extent of organ involvement. The work by OSLER [2], LIBMANN and SACKS [3], and KLEMPERER [4] best represents these advances. The increase in clinical knowledge of LE finally led to DUBOIS' famous monograph [5], which was pub lished at a time of renewed interest in SLE, elicited by the descrip tion by HARGRAVES et al. [6] of the LE-cell phenomenon. A more detailed analysis of this finding revealed that the disease was charac terized by an abnormal immune response, although its pathogenetic implications were still unclear.
Author : Peter A. Miescher
Publisher : Springer Science & Business Media
Page : 225 pages
File Size : 42,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642796227
During the past 50 years, systemic lupus erythematosus (SLE) has been the main subject in the field of immunopathology. Each individual discovery was followed by the discovery of a multitude of related immune phenomena. This book reflects the present status of our understanding of this protean disease. Various animal models clearly show that different gene combinations can lead to the final clinical expression of SLE, with HLA class II genes probably responsible for the targeting of the autoimmune response. Similarly, research on cytokines in SLE patients has shown that SLE is a syndrome depending on different pathways. Finally, the question of prognosis is discussed. Fortunately, with every passing decade, the prognosis for patients with SLE gets better and better.
Author : Daniel J. Wallace
Publisher : Oxford University Press
Page : 130 pages
File Size : 49,6 Mb
Release : 2014-03
Category : Medical
ISBN : 9780199361960
This book serves as a concise resource on the accurate diagnosis and appropriate management of lupus. It is a practical, evidence-based volume that describes the pathophysiology of the condition, diagnostic strategies and tools, as well as current and emergerging therapeutic options.
Author : George Tsokos
Publisher : Academic Press
Page : 640 pages
File Size : 43,7 Mb
Release : 2015-12-23
Category : Medical
ISBN : 9780128020098
Systemic Lupus Erythematosus combines basic science with clinical science to provide a translational treatment of the disease and is a useful reference for specialists in the diagnosis and management of patients with SLE, a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease and a reference work for hospital libraries. Provides the very latest overview of the pathogenesis of SLE Distills current understanding of the cellular, molecular, genetic and environmental factors that instigate and drive the disease Includes comprehensive coverage of clinical features, including fatigue, organ system manifestations, overlap syndromes, infections, and more Conveys the very latest understanding of mechanisms of tissue damage, including immune complexes, antibodies, and other mechanisms that lead to organ damage Discusses the latest treatment options on disease modifying or disease controlling agents Provides 'one stop' coverage of all the latest scientific and clinical developments in SLE
Author : Zahi Touma,Alfred Kim
Publisher : Elsevier Health Sciences
Page : 257 pages
File Size : 47,5 Mb
Release : 2021-07-06
Category : Medical
ISBN : 9780323835572
This issue of Rheumatic Disease Clinics, guest edited by Dr. Alfred Kim and Zahi Touma, will discuss a number of key topics surrounding Lupus. This issue is one of four selected each year by series Consulting Editor, Dr. Michael Weisman. Topics discussed in this issue include, but are not limited to: Interferons in SLE, NETosis and neutrophils in SLE, AMP update in lupus nephritis, Patient-reported outcomes, Complement, T cells in SLE, B cells in SLE, Outcome measures for SLE clinical trials, Mitochondrial physiology in SLE, Pregnancy, Lupus cohorts, Innovative trials and new opportunities in SLE, Classification and diagnosis of SLE, and Updates on SLE Treatment.
Author : David Isenberg,Susan Manzi
Publisher : Oxford University Press
Page : 110 pages
File Size : 53,6 Mb
Release : 2008-01-17
Category : Health & Fitness
ISBN : 9780199213870
Reflects major developments in understanding of the causes of lupus and discusses treatment options, managing lupus on a day-to-day basis and offers advice for families, friends and carers.
Author : Peter H. Schur,Elena M. Massarotti
Publisher : Springer
Page : 260 pages
File Size : 48,9 Mb
Release : 2014-08-08
Category : Medical
ISBN : 1489994610
Often considered the prototypic autoimmune disease, Lupus is characterized by protean manifestations and affects a wide range of organ systems. Despite widespread availability of anti nuclear antibody testing and other technological diagnostic advances, the diagnosis of lupus can be elusive, difficult, and inexact. Treatment of the disease can also be challenging. Advances in immunology and biotechnology have led to a burgeoning world of new therapies in development that offer patients the real possibility of new therapies and physicians and scientists novel insights into the pathogenesis of this complicated immunological disease. Lupus Erythematosus: Clinical Evaluation and Treatment summarizes the clinical aspects of lupus facing the general clinician in the 21st century. In this invaluable, practical book, the reader will find introductory chapters regarding general diagnostic and treatment principles, followed by chapters addressing the lupus-specific organ manifestations. Special topics regarding pregnancy and comorbidities are also presented. Written by highly experienced physicians with special expertise in lupus, Lupus Erythematosus: Clinical Evaluation and Treatment is an indispensable reference for the common and not so common problems affecting patients with lupus.
Author : Zahi Touma
Publisher : Springer Nature
Page : 418 pages
File Size : 40,5 Mb
Release : 2021-07-22
Category : Medical
ISBN : 9783030733032
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that manifests with a myriad of clinical and laboratory features. The assessment of SLE is comprehensive and includes different core set domains; disease activity, damage, health-related quality of life, adverse events and economic impact. This comprehensive book is focused on the instruments and outcome measures utilized in the assessment of SLE. It targets different audiences including physicians, scientists/researchers and different health professionals interested in learning about the art of measurement in SLE. The book highlights the importance of measurement in the assessment of SLE in a clinical settings, research and clinical trials. Each of the chapters provide a systematic approach to the instruments utilized in the assessment of a specific construct in SLE (e.g., disease activity, fatigue, etc.) and incorporate a comprehensive coverage of disease specific and disease generic measures. It also discusses different patient-reported outcomes that are crucial to reflect patient perceptions of their health condition and cover constructs such as fatigue, pain, anxiety and depression, cognition, frailty, and many others.
Author : Daniel Wallace,Bevra Hannahs Hahn
Publisher : Elsevier Health Sciences
Page : 752 pages
File Size : 46,8 Mb
Release : 2018-08-16
Category : Medical
ISBN : 9780323550642
For more than 50 years, Dubois’ Lupus Erythematosus and Related Syndromes has been recognized internationally as the go-to clinical reference on lupus and other connective tissue diseases. From basic scientific principles to practical points of clinical management, the updated 9th Edition provides extensive, authoritative coverage of systemic lupus erythematosus (SLE) and its related diseases in a logical, clearly written, user-friendly manner. It’s an ideal resource for rheumatologists and internal medicine practitioners who need a comprehensive clinical reference on all aspects of SLE, connective tissue diseases, and the antiphospholipid syndromes. Provides complete clinical coverage of every aspect of cutaneous and systemic lupus erythematosus, including definitions, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education. Contains an up-to-date overview of significant advances in cellular, molecular, and genetic technologies, including genetic advancements in identifying at-risk patients. Offers an increased focus on the clinical management of related disorders such as Sjogren’s syndrome, scleroderma, polymyositis, and antiphospholipid syndrome (APS). Presents the knowledge and expertise of more international contributors to provide new global perspectives on manifestations, diagnosis, and treatment. Features a vibrant, full-color format, with graphs, algorithms, differential diagnosis comparisons, and more schematic diagrams throughout.
Author : D P Lyle
Publisher : Medallion Media Group
Page : 406 pages
File Size : 53,6 Mb
Release : 2012-04-01
Category : Language Arts & Disciplines
ISBN : 9781605423975
This compilation of medical and forensic science questions from crime writers around the world provides insight into medical and forensic science as well as a glimpse into the writer’s creative mind. How do hallucinogenic drugs affect a blind person? Will snake venom injected into fruit cause death? How would you perform CPR in a helicopter? What happens when someone swallows razor blades? How long does it take blood to dry? Can DNA be obtained from a half-eaten bagel? D. P. Lyle, MD, answers these and many more intriguing questions. The book is a useful and entertaining resource for writers and screenwriters, helping them find the information they need to frame a situation and write a convincing description. TV viewers, readers who enjoy crime fiction, and those who want to know more about forensic science can keep up with the news and understand the science behind criminal investigation. From traumatic injuries to the coroner’s office, the questions and answers are divided into five parts, making it a compendium of the incredible information that lies within the world of medicine and forensics.
Author : Donald E. Thomas Jr.
Publisher : JHU Press
Page : 845 pages
File Size : 45,6 Mb
Release : 2023-09-05
Category : Health & Fitness
ISBN : 9781421446851
Now completely updated! The best-selling, most comprehensive guide to lupus, its complications, and management. Lupus is an autoimmune disease that can attack any body organ. It is three times more common in the United States today than it was in the 1980s, so there is an increased need for accurate, practical information on this potentially devastating disease. Lupus expert and clinician Donald E. Thomas, Jr., MD, provides all the helpful information patients need so they can understand and treat this disease. Highlighting amazing advancements in the diagnosis and treatment of lupus, this edition includes new and expanded information on: • The latest FDA-approved medications • How lupus affects different body parts • Advanced labs that improve lupus diagnosis and treatment • The role of the microbiome and anti-inflammatory diets • Updated recommendations for those who are pregnant or breastfeeding • Childhood-onset lupus • The interaction between COVID-19 and lupus • Non-drug treatments, complementary medicine, and medical cannabis The gold standard since it was first published and carefully reviewed by experts in the field, the latest edition of The Lupus Encyclopedia is essential for patients, health care providers, and families. Bonus content on insurance issues and information about working with lupus and disability is also available online. Endorsed by The Lupus Foundation of America Contributors: Jemima Albayda, MD; Divya Angra, MD; Alan N. Baer, MD; Sasha Bernatsky, MD, PhD; George Bertsias, MD, PhD; Ashira D. Blazer, MD; Ian Bruce, MD; Jill Buyon, MD; Yashaar Chaichian, MD; Maria Chou, MD; Sharon Christie, Esq; Angelique N. Collamer, MD; Ashté Collins, MD; Caitlin O. Cruz, MD; Mark M. Cruz, MD; Dana DiRenzo, MD; Jess D. Edison, MD; Titilola Falasinnu, PhD; Andrea Fava, MD; Cheri Frey, MD; Neda F. Gould, PhD; Nishant Gupta, MD; Sarthak Gupta, MD; Sarfaraz Hasni, MD; David Hunt, MD; Mariana J. Kaplan, MD; Alfred Kim, MD; Deborah Lyu Kim, DO; Rukmini Konatalapalli, MD; Fotios Koumpouras, MD; Vasileios C. Kyttaris, MD; Jerik Leung, MPH; Hector A. Medina, MD; Timothy Niewold, MD; Julie Nusbaum, MD; Ginette Okoye, MD; Sarah L. Patterson, MD; Ziv Paz, MD; Darryn Potosky, MD; Rachel C. Robbins, MD; Neha S. Shah, MD; Matthew A. Sherman, MD; Yevgeniy Sheyn, MD; Julia F. Simard, ScD; Jonathan Solomon, MD; Rodger Stitt, MD; George Stojan, MD; Sangeeta Sule, MD; Barbara Taylor, CPPM, CRHC; George Tsokos, MD; Ian Ward, MD; Emma Weeding, MD; Arthur Weinstein, MD; Sean A. Whelton, MD