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Lymphoma and Leukemia of the Nervous System by Tracy Batchelor,Lisa M. DeAngelis Pdf
This is the second edition of a book called "Lymphoma of the Nervous System," which was published by Butterworth-Heinemann (B-H) in 2004. Lymphoma and Leukemia of the Nervous System is a comprehensive review of this challenging group of diseases and should be useful for the practicing neurologist, hematologist, oncologist and for any practitioner involved in the management of these patients.
Lymphoma of the Nervous System by Tracy Batchelor Pdf
This one-of-a-kind resource provides practical guidance on the recognition and treatment of lymphoma of the nervous system, including primary central nervous system lymphoma and neurological complications of systemic lymphoma. Leading experts in the field comprehensively cover the epidemiology, pathology, diagnosis, neuroimaging, and treatment for the full range of disorders.
Central Nervous System Leukemia by Renato Mastrangelo,D.G. Poplack,Riccardo Riccardi Pdf
In the past 10 to IS years there has been dramatic improvement in the survival of children with acute lymphoblastic leukemia. At the present time, over 50% of children with this disease will be alive and free of their disease at least 5 years from the time of their initial diagnosis. Although a number of factors have contributed to this improvement, perhaps none has been as important as the institution of central nervous system preventive therapy (eNS prophylaxis). However, despite the efficacy of eNS prophylaxis, the prevention and treatment of central nervous system leukemia continues to pose a formidable clinical challenge to the pediatric oncologist. Although successful in most cases, eNS preventive therapy remains ineffective for a small but significant subset of patients at high risk for developing eNS disease. Moreover, it has become increasingly evident that some methods of eNS preventive therapy are associated with long-term, adverse eNS sequelae. Thus, considerable controversy exists regarding the optimal method of eNS prophylaxis. Treatment of the patient who develops overt meningeal leukemia has not been as successful and continues to pose a major clinical challenge. Despite the ability of intrathecal chemotherapy and/or radiation therapy to induce eNS remission, most patients suffer subsequent relapse and ultimate survival is usually signifi cantly compromised. It is evident that newer approaches to treatment for this patient group must be identified before major improvement for this patient group is likely to occur.
Author : David Schiff,Santosh Kesari,Patrick C. Y. Wen Publisher : Springer Science & Business Media Page : 636 pages File Size : 47,6 Mb Release : 2008-07-11 Category : Medical ISBN : 9781597454124
Cancer Neurology in Clinical Practice by David Schiff,Santosh Kesari,Patrick C. Y. Wen Pdf
Neuro-oncology has evolved substantially as a clinical and research discipline over the past few decades. Cancer Neurology in Clinical Practice: Neurologic Complications of Cancer and its Treatment, Second Edition provides clinicians from various backgrounds and levels of training with a reference to help focus the differential diagnosis, treatment strategy, and management plan for the cancer patient with neurologic symptoms and findings. The volume begins with an overview of the field of neuro-oncology and a review of the role of neuroimaging in the diagnosis of neuro-oncologic disease. Several chapters on interpretation and management of common neuro-oncologic symptoms follow. Subsequent sections contain chapters on the direct and indirect neurologic complications of cancer as well as complications of therapy. The final section focuses on the spectrum and management of neurologic disease in patients with cancer of specific organs. Cancer Neurology in Clinical Practice: Neurologic Complications of Cancer and its Treatment, Second Edition is an important new work that aims to broaden and deepen the familiarity of clinicians with the range and management of neuro-oncologic diseases in order to improve the quality of care for cancer patients.
Malignant Lymphomas of the Nervous System by K. Jellinger,F. Seitelberger Pdf
More than 150 years have passed since involvement of the nervous system in leukemia was first reported by BURNS, while the possibility of the primary brain tumor derived from the lymphoreticular tissue was recognized much later. BAILEY in 1929 described such neoplasms under the term perithelial sarcoma. Later these tumors of the nervous system have been variously designated as "Perivascular of perithelial sarcomas, reticulum cell sarcomas or microgliomas", as controversy has evolved and still exists on the definition of this group of neoplasms and on the nature of their cells of origin. Much of the unfortunate confusion concerning the neoplastic lesions attributed to "microglia" and other derivations of the RE system arose because their close relationship to extra neural cells has been ignored. On the other hand, communication in the field of malignant lymphomas has become increasingly difficult because of the termino logic maze and conceptual diversities of traditional morphological classifica tions that have limited valid comparisons. Although at present we are still far from a precise recognition of the basic features of lymphoproliferative processes and from a fairly general agreement on the terminology of non-Hodgkin lymphomas, there is encouraging evidence recently of some enlightment on the nature of tumor cells that provides the basis for a reasonable and generally acceptable lymphoma classification.
Brain Metastases by Jeffrey Raizer,Lauren E. Abrey Pdf
Brain metastases are the most dreaded complication of systemic cancer, affecting some 170,000 people a year, a far greater incidence than primary brain tumors. This book presents current information on the presentation and management of patients with brain metastases, providing available data, giving guidelines that can be applied in day to day practice, updated information for neurosurgeons, radiation oncologists, medical oncologists, and neuron-oncologists, and as an overview for physicians in training.
Central Nervous System Metastases by Manmeet Ahluwalia,Philippe Metellus,Riccardo Soffietti Pdf
This book provides a comprehensive overview of brain metastases, from the molecular biology aspects to therapeutic management and perspectives. Due to the increasing incidence of these tumors and the urgent need to effectively control brain metastatic diseases in these patients, new therapeutic strategies have emerged in recent years. The volume discusses all these innovative approaches combined with new surgical techniques (fluorescence, functional mapping, integrated navigation), novel radiation therapy techniques (stereotactic radiosurgery) and new systemic treatment approaches such as targeted- and immunotherapy. These combination strategies represent a new therapeutic model in brain metastatic patients in which each medical practitioner (neurosurgeon, neurologist, medical oncologist, radiation oncologist) plays a pivotal role in defining the optimal treatment in a multidisciplinary approach. Written by recognized experts in the field, this book is a valuable tool for neurosurgeons, neuro-oncologists, neuroradiologists, medical oncologists, radiation oncologists, cognitive therapists, basic scientists and students working in the area of brain tumors.
Childhood Acute Lymphoblastic Leukemia by Ajay Vora Pdf
This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.
Author : L. E. Broder,Stephen K. Carter Publisher : Springer Page : 152 pages File Size : 42,5 Mb Release : 1972 Category : Medical ISBN : UOM:39015072219606
Meningeal Leukemia by L. E. Broder,Stephen K. Carter Pdf
Meningeal leukemia (ML) is a well-known and rather frequent complication of leukemia especially since the advent of chemotherapy. The first report of neurological complications of leukemia was in 1823 by Burnsl. Before leukemia chemotherapy, there had been only sporadic and relatively few case reports. However, since 1948, the incidence of meningeal leukemia has increased to where it is now one of the most frequent complications of the disease. This review will discuss in depth the pathology, clinical characteristics, and results of treatment of meningeal leukemia. An attempt will be made to assess the relative values of different modes of therapy and suggest new ones in light of animal studies and theoretical models for meningeal leukemia, and to define what parameters are necessary in evaluating the results of therapy, which would be helpful in future studies. This is especially cogent since many of the more recent chemotherapy proto cols are utilizing combinations of radiotherapy and intrathecal therapy both in treatment of meningeal leu kemia and as prophylaxis against its development.
Non-Hodgkin's Lymphoma in Childhood and Adolescence by Oussama Abla,Andishe Attarbaschi Pdf
This text provides a state-of-the-art overview on Non-Hodgkin's lymphoma (NHL) in children and adolescents. The volume is divided into seven sections, each of which focuses on a critical component of pediatric NHL, including history and epidemiology, pathology and molecular biology, disease evaluation and response, common and rare sub-types of NHL, and current and novel treatment strategies. The text also comprehensively reviews the late effects of treatment, quality of patient life, and NHL treatment in countries with limited resources. Written by experts in the field, Non-Hodgkin's Lymphoma in Childhood and Adolescence is a valuable resource for clinicians and practitioners who treat children and adolescents with NHL.
Author : Lisa M. DeAngelis,Lauren E. Abrey Publisher : W B Saunders Company Page : 240 pages File Size : 51,6 Mb Release : 2005 Category : Medical ISBN : 1416027750
Central Nervous System Lymphomas by Lisa M. DeAngelis,Lauren E. Abrey Pdf
The full spectrum of central nervous system lymphoma is coverered from patheology and genetics to clinical features, diagnosis and treatment. Also explored are new approches to therapy and unusual variants of central nervous system lymphoma.
