Management Of Spastic Conditions Of The Upper Extremity An Issue Of Hand Clinics E Book

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Management of Spastic Conditions of the Upper Extremity, An Issue of Hand Clinics E-Book

Joshua M Adkinson
Management of Spastic Conditions of the Upper Extremity An Issue of Hand Clinics E Book Book PDF

Author : Joshua M Adkinson
Publisher : Elsevier Health Sciences
Page : 128 pages
File Size : 54,9 Mb
Release : 2018-10-05
Category : Medical
ISBN : 9780323641524

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Management of Spastic Conditions of the Upper Extremity, An Issue of Hand Clinics E-Book by Joshua M Adkinson Pdf

This issue of Hand Clinics, guest edited by Dr. Joshua Adkinson, will cover several import aspects of the Management of Spastic Conditions of the Upper Extremity. At the invitation of consulting editor Dr. Kevin Chung, Dr. Adkinson put together a comprehensive issue, which covers: Etiologies; Assessment measures and motion analysis; Non-surgical treatment options; Surgical management of spasticity of the thumb and fingers, wrist and forearm, elbow, and shoulder; Management of spastic upper extremity joint contractures; Technical pearls of tendon transfers; Selective neurotomy; Neurosurgical management; Outcomes after surgical treatment; The future of upper extremity spasticity management; and Management of spinal cord injury-induced upper limb spasticity, among others.

Rehabilitation of the Hand and Upper Extremity, E-Book

Terri M. Skirven,A. Lee Osterman,Jane Fedorczyk,Peter C. Amadio,Sheri Felder,Eon K Shin
Rehabilitation of the Hand and Upper Extremity E Book Book PDF

Author : Terri M. Skirven,A. Lee Osterman,Jane Fedorczyk,Peter C. Amadio,Sheri Felder,Eon K Shin
Publisher : Elsevier Health Sciences
Page : 2091 pages
File Size : 47,5 Mb
Release : 2020-01-14
Category : Medical
ISBN : 9780323547154

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Rehabilitation of the Hand and Upper Extremity, E-Book by Terri M. Skirven,A. Lee Osterman,Jane Fedorczyk,Peter C. Amadio,Sheri Felder,Eon K Shin Pdf

Long recognized as an essential reference for therapists and surgeons treating the hand and the upper extremity, Rehabilitation of the Hand and Upper Extremity helps you return your patients to optimal function of the hand, wrist, elbow, arm, and shoulder. Leading hand surgeons and hand therapists detail the pathophysiology, diagnosis, and management of virtually any disorder you’re likely to see, with a focus on evidence-based and efficient patient care. Extensively referenced and abundantly illustrated, the 7th Edition of this reference is a "must read" for surgeons interested in the upper extremity, hand therapists from physical therapy or occupational therapy backgrounds, anyone preparing for the CHT examination, and all hand therapy clinics. Offers comprehensive coverage of all aspects of hand and upper extremity disorders, forming a complete picture for all members of the hand team—surgeons and therapists alike. Provides multidisciplinary, global guidance from a Who’s Who list of hand surgery and hand therapy editors and contributors. Includes many features new to this edition: considerations for pediatric therapy; a surgical management focus on the most commonly used techniques; new timing of therapeutic interventions relative to healing characteristics; and in-print references wherever possible. Features more than a dozen new chapters covering Platelet-Rich Protein Injections, Restoration of Function After Adult Brachial Plexus Injury, Acute Management of Upper Extremity Amputation, Medical Management for Pain, Proprioception in Hand Rehabilitation, Graded Motor Imagery, and more. Provides access to an extensive video library that covers common nerve injuries, hand and upper extremity transplantation, surgical and therapy management, and much more. Helps you keep up with the latest advances in arthroscopy, imaging, vascular disorders, tendon transfers, fingertip injuries, mobilization techniques, traumatic brachial plexus injuries, and pain management—all clearly depicted with full-color illustrations and photographs.

Use of Sonography in Hand/Upper Extremity Surgery - Innovative Concepts and Techniques, An Issue of Hand Clinics, E-Book

Frederic Schuind,Fabian Moungondo,Luc Van Overstraeten
Use of Sonography in Hand Upper Extremity Surgery Innovative Concepts and Techniques An Issue of Hand Clinics E Book Book PDF

Author : Frederic Schuind,Fabian Moungondo,Luc Van Overstraeten
Publisher : Elsevier Health Sciences
Page : 240 pages
File Size : 42,8 Mb
Release : 2021-11-26
Category : Medical
ISBN : 9780323835794

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Use of Sonography in Hand/Upper Extremity Surgery - Innovative Concepts and Techniques, An Issue of Hand Clinics, E-Book by Frederic Schuind,Fabian Moungondo,Luc Van Overstraeten Pdf

In this issue of Hand Clinics, guest editors Frédéric Schuind, Fabian Moungondo, and Luc Van Overstraeten bring their considerable expertise to the topic of The Use of Sonography in Hand/Upper Extremity Surgery. Top experts in the field cover key topics such as Flexor Tendons Sonography, Sonographic Diagnosis of Carpal Tunnel Syndrome, Atlas of Sonographic Anatomy of the Hand and Wrist, and more. Contains 9 relevant, practice-oriented topics including Nerve Ultrasound-Assisted Surgery for Neuropathic Pain and Joint Denervation; Preoperative Evaluation of Thenar Muscles in Carpal Tunnel Syndrome by Ultrasonograph; Shear Wave Ultrasound Elastography for Hand Soft Tissue Assessment; and more. Provides in-depth clinical reviews on the use of sonography in Hand/Upper Extremity Surgery, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Introduction to Splinting- E-Book

Brenda M. Coppard,Helene Lohman
Introduction to Splinting E Book Book PDF

Author : Brenda M. Coppard,Helene Lohman
Publisher : Elsevier Health Sciences
Page : 540 pages
File Size : 50,8 Mb
Release : 2013-08-07
Category : Medical
ISBN : 9780323266437

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Introduction to Splinting- E-Book by Brenda M. Coppard,Helene Lohman Pdf

The third edition of Introduction to Splinting: A Clinical Reasoning and Problem-Solving Approach helps readers master the basic theory, principles, and techniques of splinting needed for clinical practice. Using a combination textbook/workbook format, it integrates theory and technical knowledge with hands-on learning features that equip readers with essential clinical knowledge, critical thinking skills, and problem-solving skills associated with splinting. This title includes additional digital media when purchased in print format. For this digital book edition, media content may not be included.

Muscle Over-activity in Upper Motor Neuron Syndrome: Assessment and Problem Solving for Complex Cases, An Issue of Physical Medicine and Rehabilitation Clinics of North America E-Book

Miriam Segal
Muscle Over activity in Upper Motor Neuron Syndrome Assessment and Problem Solving for Complex Cases An Issue of Physical Medicine and Rehabilitation Clinics of North America E Book Book PDF

Author : Miriam Segal
Publisher : Elsevier Health Sciences
Page : 128 pages
File Size : 51,8 Mb
Release : 2018-07-15
Category : Medical
ISBN : 9780323614092

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Muscle Over-activity in Upper Motor Neuron Syndrome: Assessment and Problem Solving for Complex Cases, An Issue of Physical Medicine and Rehabilitation Clinics of North America E-Book by Miriam Segal Pdf

This issue of Physical Medicine and Rehabilitation Clinics, guest edited by Dr. Miriam Segal, will cover the important topic of Muscle Overactivity in Upper Motor Neuron Syndrome, including assessment and problem-solving for complex cases. Topics discussed in the volume will include: Functional/problem based assessment in patients with spinal cord injury; Special considerations in pediatric assessment; Special considerations and assessment of spasticity and multiple sclerosis; Pharmacologic treatment tools; Peripheral neurolysis; The role of physical and occupational therapy; Neurosurgical approaches; The neuro-orthopedic approach; Upper extremity problem-solving: Challenging cases; Lower extremity problem-solving: Challenging cases; and Emerging therapies.

Botulinum Toxin E-Book

Joseph Jankovic,Alberto Albanese,M. Zouhair Atassi,J. Oliver Dolly,Mark Hallett,Nathaniel H. Mayer
Botulinum Toxin E Book Book PDF

Author : Joseph Jankovic,Alberto Albanese,M. Zouhair Atassi,J. Oliver Dolly,Mark Hallett,Nathaniel H. Mayer
Publisher : Elsevier Health Sciences
Page : 527 pages
File Size : 46,6 Mb
Release : 2009-02-18
Category : Medical
ISBN : 9781437711196

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Botulinum Toxin E-Book by Joseph Jankovic,Alberto Albanese,M. Zouhair Atassi,J. Oliver Dolly,Mark Hallett,Nathaniel H. Mayer Pdf

The new, therapeutically-focused Botulinum Toxin presents comprehensive, cross-disciplinary guidance on current practices, covering more than 100 non-cosmetic conditions that occur in neurology, physical medicine and rehabilitation, pain medicine, ophthalmology, gastroenterology, urology, orthopedics, and surgery. International contributors review the current understanding of the biology and cellular mechanisms along with relevant research so you can easily apply them to the pathophysiology of the numerous disorders that botulinum toxin is used to treat—such as botulinum toxin applications for the treatment of cranial-cervical dystonias, motor disorders in cerebral palsy, bruxism and temporomandibular disorders, headache, overactive bladder, chronic pelvic pain syndromes, arthritis joint pain, and wound healing. With discussions of the latest in approved treatment practices as well as new and emerging uses, you’ll get in-depth management guidance on the application of the toxin. Provides clinical applications of botulinum toxin for over 100 disorders for immediate access and easy reference during practice and treatment. Covers a broad array of hot topics, including botulinum toxin applications for the treatment of cranial-cervical dystonias, motor disorders in cerebral palsy, bruxism and temporomandibular disorders, headache, overactive bladder, chronic pelvic pain syndromes, arthritis joint pain, and wound healing. Focuses on approved uses with expert advice on thoroughly tested applications but also discusses new and emerging applications to expose you to additional treatment options. Presents the most comprehensive and up-to-date material available so you get all the information you need from this one resource. Offers the cross-disciplinary guidance of the best world-class expertise through an authoritative, international group of authors who demonstrate the applications of botulinum toxin across various specialties.

Brain Neurotrauma

Firas H. Kobeissy
Brain Neurotrauma Book PDF

Author : Firas H. Kobeissy
Publisher : CRC Press
Page : 725 pages
File Size : 54,6 Mb
Release : 2015-02-25
Category : Science
ISBN : 9781466565999

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Brain Neurotrauma by Firas H. Kobeissy Pdf

Every year, an estimated 1.7 million Americans sustain brain injury. Long-term disabilities impact nearly half of moderate brain injury survivors and nearly 50,000 of these cases result in death. Brain Neurotrauma: Molecular, Neuropsychological, and Rehabilitation Aspects provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma, including brain injury pathophysiology, biomarker research, experimental models of CNS injury, diagnostic methods, and neurotherapeutic interventions as well as neurorehabilitation strategies in the field of neurotraum research. The book includes several sections on neurotrauma mechanisms, biomarker discovery, neurocognitive/neurobehavioral deficits, and neurorehabilitation and treatment approaches. It also contains a section devoted to models of mild CNS injury, including blast and sport-related injuries. Over the last decade, the field of neurotrauma has witnessed significant advances, especially at the molecular, cellular, and behavioral levels. This progress is largely due to the introduction of novel techniques, as well as the development of new animal models of central nervous system (CNS) injury. This book, with its diverse coherent content, gives you insight into the diverse and heterogeneous aspects of CNS pathology and/or rehabilitation needs.

Introduction to Orthotics E-Book

Brenda M. Coppard,Helene Lohman
Introduction to Orthotics E Book Book PDF

Author : Brenda M. Coppard,Helene Lohman
Publisher : Elsevier Health Sciences
Page : 528 pages
File Size : 52,5 Mb
Release : 2019-02-21
Category : Medical
ISBN : 9780323549707

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Introduction to Orthotics E-Book by Brenda M. Coppard,Helene Lohman Pdf

Develop the critical thinking skills you need to choose and fit effective orthoses for patients with hand injuries and functional deficits. As a combination workbook/textbook, Introduction to Orthotics, 5th Edition uses reader friendly language to cover the theory, design, and fabrication of orthopedic devices. Ideal for use in the classroom or in the clinical setting, it emphasizes upper extremity versus hand orthoses, with additional coverage of lower extremity orthotics and upper extremity prosthetics, and offers case studies promoting clinical reasoning and problem solving as well as an occupation-based approach. This new edition also demonstrates the fine detail of orthotics and equips you with a repertoire of skills and knowledge related to orthoses. Updated content, references, grading forms and self-evaluation, and case studies provide students and practitioners with the most current and up-to-date information they need to prepare to serve their clients’ needs. Combined textbook/workbook format makes it easier to develop fundamental skills in the theory, design, and fabrication of orthoses Numerous case studies in each chapter show how concepts relate to real-life clinical practice. How-To videos on the Evolve companion website let students watch the construction of orthotics again and again to increase their proficiency. Integration of patient safety addresses this important aspect of patient care. Spiral binding lets the book lay flat when opened for convenient use while on the job. Self-evaluation forms allow you to analyze personal strengths and weaknesses related to new orthotic intervention techniques. Review questions and self-quizzes reinforce your comprehension of the material. Laboratory exercises test your clinical reasoning and technical skills. NEW! chapter covering Casting techniques provides guidance regarding current advances. NEW! Chapter for Professional Issues Related to Orthotic Provision. NEW! Elbow, Forearm, and Shoulder Immobilization Orthoses expands the content that previously only addressed elbow and forearm orthoses to include shoulder immobilization orthoses. NEW! Photos and illustrations for pre-fabrication, fitting, and fabrication techniques appear throughout the text. NEW! Evidence-based practice charts

Pedretti's Occupational Therapy - E-Book

Heidi McHugh Pendleton,Winifred Schultz-Krohn
Pedretti s Occupational Therapy E Book Book PDF

Author : Heidi McHugh Pendleton,Winifred Schultz-Krohn
Publisher : Elsevier Health Sciences
Page : 1325 pages
File Size : 46,8 Mb
Release : 2011-12-20
Category : Medical
ISBN : 9780323266451

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Pedretti's Occupational Therapy - E-Book by Heidi McHugh Pendleton,Winifred Schultz-Krohn Pdf

Chapter on polytrauma, post-traumatic stress disorder, and injuries related to the War on Terror teaches you how to provide OT services to this unique population. Content covers new advances in prosthetics and assistive technologies, and provides more up-to-date assessment and interventions for TBI problems related to cognitive and visual perception. Full-color design visually clarifies important concepts. Video clips on the companion Evolve website vividly demonstrate a variety of OT interventions.

Clinical Pathways in Stroke Rehabilitation

Thomas Platz
Clinical Pathways in Stroke Rehabilitation Book PDF

Author : Thomas Platz
Publisher : Springer Nature
Page : 284 pages
File Size : 41,5 Mb
Release : 2021-01-14
Category : Medical
ISBN : 9783030585051

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Clinical Pathways in Stroke Rehabilitation by Thomas Platz Pdf

This open access book focuses on practical clinical problems that are frequently encountered in stroke rehabilitation. Consequences of diseases, e.g. impairments and activity limitations, are addressed in rehabilitation with the overall goal to reduce disability and promote participation. Based on the available best external evidence, clinical pathways are described for stroke rehabilitation bridging the gap between clinical evidence and clinical decision-making. The clinical pathways answer the questions which rehabilitation treatment options are beneficial to overcome specific impairment constellations and activity limitations and are well acceptable to stroke survivors, as well as when and in which settings to provide rehabilitation over the course of recovery post stroke. Each chapter starts with a description of the clinical problem encountered. This is followed by a systematic, but concise review of the evidence (RCTs, systematic reviews and meta-analyses) that is relevant for clinical decision-making, and comments on assessment, therapy (training, technology, medication), and the use of technical aids as appropriate. Based on these summaries, clinical algorithms / pathways are provided and the main clinical-decision situations are portrayed. The book is invaluable for all neurorehabilitation team members, clinicians, nurses, and therapists in neurology, physical medicine and rehabilitation, and related fields. It is a World Federation for NeuroRehabilitation (WFNR) educational initiative, bridging the gap between the rapidly expanding clinical research in stroke rehabilitation and clinical practice across societies and continents. It can be used for both clinical decision-making for individuals and as well as clinical background knowledge for stroke rehabilitation service development initiatives.

Green's Operative Hand Surgery

Scott W. Wolfe,William C. Pederson,Scott H. Kozin,Mark S. Cohen
Green s Operative Hand Surgery Book PDF

Author : Scott W. Wolfe,William C. Pederson,Scott H. Kozin,Mark S. Cohen
Publisher : Elsevier Health Sciences
Page : 2617 pages
File Size : 50,7 Mb
Release : 2021-12-03
Category : Medical
ISBN : 9780323697941

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Green's Operative Hand Surgery by Scott W. Wolfe,William C. Pederson,Scott H. Kozin,Mark S. Cohen Pdf

Widely recognized as the gold standard reference in the field, Green's Operative Hand Surgery, 8th Edition, provides complete coverage of the surgical and nonsurgical management of the full range of upper extremity conditions. In a clearly written and well-illustrated format, it contains both foundational content for residents and fellows as well as new approaches, case-based controversies, and outcomes-based solutions for practitioners. Drs. Scott W. Wolfe, William C. Pederson, Scott H. Kozin, and Mark S Cohen, along with new, international contributing authors, provide expert perspectives and preferred methods for all aspects of today’s hand, wrist, and elbow surgery. Contains thoroughly revised and updated indications and techniques to treat the full spectrum of upper extremity disorders. Highlights the latest advances and approaches, such as wide-awake local anesthesia no tourniquet (WALANT) hand surgery, nerve transfer techniques, tendon transfer and tendon avulsion repairs, skin grafting techniques, and more. Offers nearly 140 innovative and high-resolution videos (99 are NEW) that provide real-life, step-by-step guidance on key procedures. Provides state-of-the-art information on wrist arthritis, hand trauma, new arthroplasties, targeted muscle reinnervation, wrist instability surgeries, fracture management, rehabilitation, congenital disorders, orthotic interventions, and more. Includes newly updated, high-resolution illustrations, images, and photos throughout. Presents case-based controversies and unique solutions, plus current views on what works and what does not, based on recent science and outcome measures.

Stroke Rehabilitation - E-Book

Glen Gillen
Stroke Rehabilitation E Book Book PDF

Author : Glen Gillen
Publisher : Elsevier Health Sciences
Page : 806 pages
File Size : 43,5 Mb
Release : 2010-10-25
Category : Medical
ISBN : 9780323067751

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Stroke Rehabilitation - E-Book by Glen Gillen Pdf

Three new chapters broaden your understanding of stroke intervention in the areas of Using Technology to Improve Limb Function, Managing Speech and Language Deficits after Stroke, and Parenting after Stroke. Learning activities and interactive references on a companion Evolve Resources website help you review textbook content and locate additional information.

Physical Therapy for Children - E-Book

Robert J. Palisano,Suzann K. Campbell,Margo Orlin
Physical Therapy for Children E Book Book PDF

Author : Robert J. Palisano,Suzann K. Campbell,Margo Orlin
Publisher : Elsevier Health Sciences
Page : 1105 pages
File Size : 46,8 Mb
Release : 2014-04-25
Category : Medical
ISBN : 9780323290944

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Physical Therapy for Children - E-Book by Robert J. Palisano,Suzann K. Campbell,Margo Orlin Pdf

Used as both a core textbook in PT programs and as a clinical reference, Physical Therapy for Children, 4th Edition, provides the essential information needed by PTs, both student and professional, when working with children. Like the previous bestselling editions, the 4th edition follows the practice pattern categories of the Guide to Physical Therapist Practice and uses the IFC model of the disabling process as it presents up-to-date evidence-based coverage of treatment. In this latest edition, Suzann Campbell DeLapp, Robert J. Palisano, and Margo N. Orlin have added more case studies and video clips, additional chapters and Medline-linked references online, and Evidence to Practice boxes to make it easy to find and remember important information. Provides comprehensive foundational knowledge in decision making, screening, development, motor control, and motor learning, the impairments of body function and structure, and the PT management of pediatric disorders. Reflects a family-centered care model throughout to help you understand how to involve children and their caregivers in developing and implementing intervention plans. Emphasizes an evidence-based approach that incorporates the latest research for the best outcomes. Follows the practice pattern guidelines of the Guide to Physical Therapist Practice, 2nd Edition which sets the standard for physical therapy practice. Features the International Classification of Function, Disability, and Health (ICF) of the World Health Organization (WHO) as the model for the disabling process, emphasizing activity rather than functional limitations and participation rather than disability in keeping with the book’s focus on prevention of disability. Provides extensive case studies that show the practical application of material covered in the text and are often accompanied by online video clips illustrating the condition and its management. Makes it easy to access key information with plenty of tables and boxes that organize and summarize important points. Clearly demonstrates important concepts and clinical conditions you’ll encounter in practice with over 800 illustrations. Takes learning to a deeper level with additional resources on the Evolve website featuring: Over 40 video clips that correspond to case studies and demonstrate conditions found in each chapter Helpful resources, including web links Questions and exercises you’ll find helpful when preparing for the pediatric specialist certification exam

Maternal Child Nursing Care - E-Book

Shannon E. Perry,Marilyn J. Hockenberry,Kitty Cashion,Kathryn Rhodes Alden,Ellen Olshansky,Deitra Leonard Lowdermilk
Maternal Child Nursing Care E Book Book PDF

Author : Shannon E. Perry,Marilyn J. Hockenberry,Kitty Cashion,Kathryn Rhodes Alden,Ellen Olshansky,Deitra Leonard Lowdermilk
Publisher : Elsevier Health Sciences
Page : 1643 pages
File Size : 45,7 Mb
Release : 2022-03-05
Category : Medical
ISBN : 9780323825870

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Maternal Child Nursing Care - E-Book by Shannon E. Perry,Marilyn J. Hockenberry,Kitty Cashion,Kathryn Rhodes Alden,Ellen Olshansky,Deitra Leonard Lowdermilk Pdf

Master the essentials of maternity and pediatric nursing with this comprehensive, all-in-one text! Maternal Child Nursing Care, 7th Edition covers the issues and concerns of women during their childbearing years and children during their developing years. It uses a family-centered, problem-solving approach to patient care, with guidelines supported by evidence-based practice. New to this edition is an emphasis on clinical judgment skills and a new chapter on children with integumentary dysfunction. Written by a team of experts led by Shannon E. Perry and Marilyn J. Hockenberry, this book provides the accurate information you need to succeed in the classroom, the clinical setting, and on the Next Generation NCLEX-RN® examination. Focus on the family throughout the text emphasizes the influence of the entire family in health and illness. Expert authors of the market-leading maternity and pediatric nursing textbooks combine to ensure delivery of the most accurate, up-to-date content. Information on victims of sexual abuse as parents and human trafficking helps prepare students to handle these delicate issues. Nursing Alerts highlight critical information that could lead to deteriorating or emergency situations. Guidelines boxes outline nursing procedures in an easy-to-follow format. Evidence-Based Practice boxes include findings from recent clinical studies. Emergency Treatment boxes describe the signs and symptoms of emergency situations and provide step-by-step interventions. Atraumatic Care boxes teach students how to manage pain and provide competent care to pediatric patients with the least amount of physical or psychological stress. Community Focus boxes emphasize community issues, provide resources and guidance, and illustrate nursing care in a variety of settings. Patient Teaching boxes highlight important information nurses need to communicate to patients and families. Cultural Considerations boxes describe beliefs and practices relating to pregnancy, labor and birth, parenting, and women’s health. Family-Centered Care boxes draw attention to the needs or concerns of families that students should consider to provide family-centered care.

Multiple Sclerosis

Institute of Medicine,Board on Neuroscience and Behavioral Health,Committee on Multiple Sclerosis: Current Status and Strategies for the Future
Multiple Sclerosis Book PDF

Author : Institute of Medicine,Board on Neuroscience and Behavioral Health,Committee on Multiple Sclerosis: Current Status and Strategies for the Future
Publisher : National Academies Press
Page : 457 pages
File Size : 43,5 Mb
Release : 2001-08-10
Category : Medical
ISBN : 9780309072854

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Multiple Sclerosis by Institute of Medicine,Board on Neuroscience and Behavioral Health,Committee on Multiple Sclerosis: Current Status and Strategies for the Future Pdf

Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.